Salvage of focal cerebral ischemic damage by transfusion of high O 2-affinity recombinant hemoglobin polymers in mouse

Journal of Applied Physiology

Volumn 100, Issue 5, 2006, Pages 1688-1691

  Nemoto, Masaaki ^a   Mito, Toshiaki ^a   Brinigar, William S ^b   Fronticelli, Clara ^a   Koehler, Raymond C ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Temple University   (United States)

^c DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

Blood substitute; Cerebral ischemia; Middle cerebral artery; Oxygen carrier

Indexed keywords

ALBUMIN; CYSTEINE; POLYMER; RECOMBINANT HEMOGLOBIN; TETRAMER;

ALPHA CHAIN; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA CHAIN; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL FREE SYSTEM; CONTROLLED STUDY; DISULFIDE BOND; ESCHERICHIA COLI; MALE; MIDDLE CEREBRAL ARTERY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OXYGEN AFFINITY; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIOXIDANTS; BLOOD SUBSTITUTES; BLOOD TRANSFUSION; BRAIN ISCHEMIA; CATTLE; CYSTEINE; ERYTHROCYTES; ESCHERICHIA COLI; HEMOGLOBINS; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; MICE; MICE, INBRED C57BL; OXYGEN; PLACEBOS; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; SALVAGE THERAPY;

EID: 33646403158     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01374.2005     Document Type: Article

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