Naproxen intercalates with DNA and causes photocleavage through ROS generation

FEBS Journal

Volumn 280, Issue 24, 2013, Pages 6569-6580

  Husain, Mohammed A ^a   Yaseen, Zahid ^a   Rehman, Sayeed U ^a   Sarwar, Tarique ^a   Tabish, Mohammad ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

DNA binding; docking; intercalation; naproxen; ROS

Indexed keywords

DOUBLE STRANDED DNA; ETHIDIUM BROMIDE; IODIDE; NAPROXEN; PLASMID DNA; REACTIVE OXYGEN METABOLITE; UREA;

AGAR GEL ELECTROPHORESIS; ARTICLE; CIRCULAR DICHROISM; DNA CLEAVAGE; DNA DRUG COMPLEX; DRUG DETERMINATION; DRUG DNA BINDING; DRUG MECHANISM; FLUORESCENCE RESONANCE ENERGY TRANSFER; INTERCALATION COMPLEX; IRRADIATION; MOLECULAR DOCKING; PHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL; SPECTROPHOTOMETRY; SPECTROSCOPY; VISCOSITY; WHITE LIGHT;

DNA BINDING; DOCKING; INTERCALATION; NAPROXEN; ROS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BINDING, COMPETITIVE; CATTLE; CIRCULAR DICHROISM; DNA; DNA CLEAVAGE; ETHIDIUM; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; INTERCALATING AGENTS; LIGHT; MODELS, MOLECULAR; NAPROXEN; POTASSIUM IODIDE; REACTIVE OXYGEN SPECIES;

EID: 84889665338     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12558     Document Type: Article

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