In vivo characterization of the role of tissue-specific translation elongation factor 1A2 in protein synthesis reveals insights into muscle atrophy

FEBS Journal

Volumn 280, Issue 24, 2013, Pages 6528-6540

  Doig, Jennifer ^a   Griffiths, Lowri A ^a   Peberdy, David ^a   Dharmasaroja, Permphan ^a,d   Vera, Maria ^b   Davies, Faith J C ^a   Newbery, Helen J ^a   Brownstein, David ^c   Abbott, Catherine M ^a,c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b Albert Einstein University   (United States)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d Mahidol University ^*  (Thailand)

Author keywords

motor neuron degeneration; muscle atrophy; transgenic mice; translation elongation

Indexed keywords

ATROGIN 1; ELONGATION FACTOR 1; MOLECULAR MARKER; RNA; TRANSLATION ELONGATION FACTOR 1A2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENERVATION; GENETIC REGULATION; GRIP STRENGTH; IN VIVO STUDY; MOUSE; MUSCLE ATROPHY; MUSCLE LEVEL; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RNA TRANSLATION; TIME OF DEATH; TISSUE SPECIFICITY; TRANSGENE; TRANSGENIC MOUSE; UPREGULATION; WEIGHT REDUCTION;

MUS; MUS MUSCULUS;

MOTOR NEURON DEGENERATION; MUSCLE ATROPHY; TRANSGENIC MICE; TRANSLATION ELONGATION;

ANIMALS; GENE EXPRESSION REGULATION; MICE; MICE, KNOCKOUT; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUSCULAR ATROPHY; NEURODEGENERATIVE DISEASES; NEURONS; ORGAN SPECIFICITY; PEPTIDE CHAIN ELONGATION, TRANSLATIONAL; PEPTIDE ELONGATION FACTOR 1; SKP CULLIN F-BOX PROTEIN LIGASES; UP-REGULATION;

EID: 84889656023     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12554     Document Type: Article

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