Progressive loss of motor neuron function in wasted mice: Effects of a spontaneous null mutation in the gene for the eEF1A2 translation factor

Journal of Neuropathology and Experimental Neurology

Volumn 64, Issue 4, 2005, Pages 295-303

  Newbery, Helen J ^a   Gillingwater, Thomas H ^a   Dharmasaroja, Permphan ^a   Peters, Josephine ^b   Wharton, Stephen B ^c,d   Thomson, Derek ^a   Ribchester, Richard R ^a   Abbott, Catherine M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Amyotrophic lateral sclerosis; EEF1A2; Motor neuron; Neuromuscular junction; Translation elongation; Wasted mouse

Indexed keywords

ELONGATION FACTOR; ELONGATION FACTOR EEF1A2; UNCLASSIFIED DRUG;

ABDOMINAL WALL MUSCULATURE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CELL VACUOLE; CERVICAL SPINAL CORD; DEATH; GAIT DISORDER; GENE MUTATION; GLIOSIS; HOMOZYGOTE; MOTOR NEURON DISEASE; MOTOR UNIT; MOUSE; MOUSE MUTANT; NERVE ENDING; NEUROFILAMENT; NEUROMUSCULAR SYNAPSE; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSLATION; SYNAPTIC TRANSMISSION; THORAX WALL; TREMOR;

EID: 16844380610     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/64.4.295     Document Type: Article

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