-
1
-
-
77953587132
-
Molecular markers to individualize adjuvant therapy for colon cancer
-
Gangadhar T, Schilsky RL. Molecular markers to individualize adjuvant therapy for colon cancer. Nat Rev Clin Oncol 2010;7:318-25.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 318-325
-
-
Gangadhar, T.1
Schilsky, R.L.2
-
2
-
-
80051580618
-
Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
-
Siegel R, Ward E, Brawley O, et al. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 2011;61:212-36.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 212-236
-
-
Siegel, R.1
Ward, E.2
Brawley, O.3
-
3
-
-
72449176846
-
Molecular origins of cancer: Molecular basis of colorectal cancer
-
Markowitz SD, Bertagnolli MM. Molecular origins of cancer: Molecular basis of colorectal cancer. N Engl J Med 2009;361:2449-60.
-
(2009)
N Engl J Med
, vol.361
, pp. 2449-2460
-
-
Markowitz, S.D.1
Bertagnolli, M.M.2
-
4
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988;319:525-32.
-
(1988)
N Engl J Med
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
-
5
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser AR, Pitot HC, Dove WF. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990;247:322-4.
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pitot, H.C.2
Dove, W.F.3
-
6
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006;127:469-80.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
7
-
-
0037205007
-
The promise and perils of Wnt signaling through β-catenin
-
DOI 10.1126/science.1071549
-
Moon RT, Bowerman B, Boutros M, et al. The promise and perils of Wnt signaling through beta-catenin. Science 2002;296:1644-6. (Pubitemid 34579151)
-
(2002)
Science
, vol.296
, Issue.5573
, pp. 1644-1646
-
-
Moon, R.T.1
Bowerman, B.2
Boutros, M.3
Perrimon, N.4
-
8
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
Bienz M, Clevers H. Linking colorectal cancer to Wnt signaling. Cell 2000;103:311-20.
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
9
-
-
67650379261
-
Can misfolded proteins be beneficial? the HAMLET case
-
Pettersson-Kastberg J, Aits S, Gustafsson L, et al. Can misfolded proteins be beneficial? The HAMLET case. Ann Med 2009;41:162-76.
-
(2009)
Ann Med
, vol.41
, pp. 162-176
-
-
Pettersson-Kastberg, J.1
Aits, S.2
Gustafsson, L.3
-
10
-
-
0037235684
-
HAMLET kills tumor cells by an apoptosis-like mechanism - Cellular, molecular, and therapeutic aspects
-
DOI 10.1016/S0065-230X(03)88302-1
-
Svanborg C, Agerstam H, Aronson A, et al. HAMLET kills tumor cells by an apoptosis-like mechanism-cellular, molecular, and therapeutic aspects. Adv Cancer Res 2003;88:1-29. (Pubitemid 36343277)
-
(2003)
Advances in Cancer Research
, vol.88
, pp. 1-29
-
-
Svanborg, C.1
Agerstam, H.2
Aronson, A.3
Bjerkvig, R.4
Duringer, C.5
Fischer, W.6
Gustafsson, L.7
Hallgren, O.8
Leijonhuvud, I.9
Linse, S.10
Mossberg, A.-K.11
Nilsson, H.12
Pettersson, J.13
Svensson, M.14
-
11
-
-
1542405871
-
Human α-Lactalbumin Made Lethal to Tumor Cells (HAMLET) Kills Human Glioblastoma Cells in Brain Xenografts by an Apoptosis-Like Mechanism and Prolongs Survival
-
DOI 10.1158/0008-5472.CAN-03-2661
-
Fischer W, Gustafsson L, Mossberg AK, et al. Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival. Cancer Res 2004;64:2105-12. (Pubitemid 38339460)
-
(2004)
Cancer Research
, vol.64
, Issue.6
, pp. 2105-2112
-
-
Fischer, W.1
Gustafsson, L.2
Mossberg, A.-K.3
Gronli, J.4
Mork, S.5
Bjerkvig, R.6
Svanborg, C.7
-
12
-
-
34548073069
-
Bladder cancers respond to intravesical instillation of HAMLET (human α-lactalbumin made lethal to tumor cells)
-
DOI 10.1002/ijc.22810
-
Mossberg AK, Wullt B, Gustafsson L, et al. Bladder cancers respond to intravesical instillation of HAMLET (human alpha-lactalbumin made lethal to tumor cells). IntJ Cancer 2007;121:1352-9. (Pubitemid 47293805)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.6
, pp. 1352-1359
-
-
Mossberg, A.-K.1
Wullt, B.2
Gustafsson, L.3
Mansson, W.4
Ljunggren, E.5
Svanborg, C.6
-
13
-
-
2942746332
-
Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid
-
Gustafsson L, Leijonhufvud I, Aronsson A, et al. Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid. N Engl J Med 2004;350:2663-72.
-
(2004)
N Engl J Med
, vol.350
, pp. 2663-2672
-
-
Gustafsson, L.1
Leijonhufvud, I.2
Aronsson, A.3
-
14
-
-
82455188049
-
Conserved features of cancer cells define their sensitivity to HAMLET-induced death; C-Myc and glycolysis
-
Storm P, Aits S, Puthia MK, et al. Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis. Oncogene 2011;30:4765-79.
-
(2011)
Oncogene
, vol.30
, pp. 4765-4779
-
-
Storm, P.1
Aits, S.2
Puthia, M.K.3
-
15
-
-
65349095292
-
Changes in proteasome structure and function caused by HAMLET in tumor cells
-
Gustafsson L, Aits S, Onnerfjord P, et al. Changes in proteasome structure and function caused by HAMLET in tumor cells. PloS One 2009;4:e5229.
-
(2009)
PloS One
, vol.4
-
-
Gustafsson, L.1
Aits, S.2
Onnerfjord, P.3
-
16
-
-
0034636156
-
Conversion of α-lactalbumin to a protein inducing apoptosis
-
DOI 10.1073/pnas.97.8.4221
-
Svensson M, Hakansson A, Mossberg AK, et al. Conversion of alpha-lactalbumin to a protein inducing apoptosis. Proc Natl Acad Sci USA 2000;97:4221-6. (Pubitemid 30226114)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.8
, pp. 4221-4226
-
-
Svensson, M.1
Hakansson, A.2
Mossberg, A.-K.3
Linse, S.4
Svanborg, C.5
-
17
-
-
77949425311
-
Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in ApcMin/+ mice
-
Koehl GE, Spitzner M, Ousingsawat J, et al. Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in ApcMin/+ mice. Oncogene 2010;29:1553-60.
-
(2010)
Oncogene
, vol.29
, pp. 1553-1560
-
-
Koehl, G.E.1
Spitzner, M.2
Ousingsawat, J.3
-
18
-
-
0030923587
-
β-Catenin mutations in cell lines established from human colorectal cancers
-
DOI 10.1073/pnas.94.19.10330
-
Ilyas M, Tomlinson IP, Rowan A, et al. Beta-catenin mutations in cell lines established from human colorectal cancers. Proc Natl Acad Sci USA 1997;94:10330-4. (Pubitemid 27407041)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.19
, pp. 10330-10334
-
-
Ilyas, M.1
Tomlinson, I.P.M.2
Rowan, A.3
Pignatelli, M.4
Bodmer, W.F.5
-
19
-
-
0028578064
-
Assembly of the cadherin-catenin complex in vitro with recombinant proteins
-
Aberle H, Butz S, Stappert J, et al. Assembly of the cadherin-catenin complex in vitro with recombinant proteins. J Cell Sci 1994;107:3655-63.
-
(1994)
J Cell Sci
, vol.107
, pp. 3655-3663
-
-
Aberle, H.1
Butz, S.2
Stappert, J.3
-
20
-
-
0034717270
-
Apoptosis-induced cleavage of β-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential
-
DOI 10.1074/jbc.M001458200
-
Steinhusen U, Badock V, Bauer A, et al. Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential. J Biol Chem 2000;275:16345-53. (Pubitemid 30366951)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.21
, pp. 16345-16353
-
-
Steinhusen, U.1
Badock, V.2
Bauer, A.3
Behrens, J.4
Wittman-Liebold, B.5
Dorken, B.6
Bommert, K.7
-
21
-
-
0034719170
-
GSK-3β-dependent phosphorylation of adenomatous polyposis cop gene product can be modulated by β-catenin and protein phosphatase 2A complexed with Axin
-
Ikeda S, Kishida M, Matsuura Y, et al. GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin. Oncogene 2000;19:537-45. (Pubitemid 30099367)
-
(2000)
Oncogene
, vol.19
, Issue.4
, pp. 537-545
-
-
Ikeda, S.1
Kishida, M.2
Matsuura, Y.3
Usui, H.4
Kikuchi, A.5
-
22
-
-
77951881189
-
AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of beta-catenin at ser 552
-
Zhao J, Yue W, Zhu MJ, et al. AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of beta-catenin at Ser 552. Biochem Biophys Res Commun 2010;395:146-51.
-
(2010)
Biochem Biophys Res Commun
, vol.395
, pp. 146-151
-
-
Zhao, J.1
Yue, W.2
Zhu, M.J.3
-
23
-
-
29144506662
-
Ion channels and cancer
-
DOI 10.1007/s00232-005-0781-4
-
Kunzelmann K. Ion channels and cancer. J Membr Biol 2005;205:159-73. (Pubitemid 41803693)
-
(2005)
Journal of Membrane Biology
, vol.205
, Issue.3
, pp. 159-173
-
-
Kunzelmann, K.1
-
24
-
-
33845373278
-
Colorectal cancer and genetic alterations in the Wnt pathway
-
DOI 10.1038/sj.onc.1210059, PII 1210059
-
Segditsas S, Tomlinson I. Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene 2006;25:7531-7. (Pubitemid 44885752)
-
(2006)
Oncogene
, vol.25
, Issue.57
, pp. 7531-7537
-
-
Segditsas, S.1
Tomlinson, I.2
-
25
-
-
0038783316
-
Secreted antagonists of the Wnt signalling pathway
-
DOI 10.1242/jcs.00623
-
Kawano Y, Kypta R. Secreted antagonists of the Wnt signalling pathway. J Cell Sci 2003;116:2627-34. (Pubitemid 36857216)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.13
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
26
-
-
1642512639
-
Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex
-
DOI 10.1016/S1535-6108(03)00334-9
-
Lepourcelet M, Chen YN, France DS, et al. Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cell 2004;5:91-102. (Pubitemid 38121599)
-
(2004)
Cancer Cell
, vol.5
, Issue.1
, pp. 91-102
-
-
Lepourcelet, M.1
Chen, Y.-N.P.2
France, D.S.3
Wang, H.4
Crews, P.5
Petersen, F.6
Bruseo, C.7
Wood, A.W.8
Shivdasani, R.A.9
-
28
-
-
78650840096
-
Ibuprofen inhibits activation of nuclear {beta}-catenin in human colon adenomas and induces the phosphorylation of GSK-3{beta}
-
Greenspan EJ, Madigan JP, Boardman LA, et al. Ibuprofen inhibits activation of nuclear {beta}-catenin in human colon adenomas and induces the phosphorylation of GSK-3{beta}. Cancer Prev Res (Phila) 2011;4:161-71.
-
(2011)
Cancer Prev Res (Phila)
, vol.4
, pp. 161-171
-
-
Greenspan, E.J.1
Madigan, J.P.2
Boardman, L.A.3
-
29
-
-
0033065458
-
Apoptosis-associated cleavage of β-catenin in human colon cancer and rat hepatoma cells
-
DOI 10.1016/S1357-2725(98)00119-8, PII S1357272598001198
-
Fukuda K. Apoptosis-associated cleavage of beta-catenin in human colon cancer and rat hepatoma cells. Int J Biochem Cell Biol 1999;31:519-29. (Pubitemid 29112912)
-
(1999)
International Journal of Biochemistry and Cell Biology
, vol.31
, Issue.3-4
, pp. 519-529
-
-
Fukuda, K.1
-
30
-
-
84934444496
-
Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells)
-
Hallgren O, Aits S, Brest P, et al. Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells). Adv Exp Med Biol 2008;606:217-40.
-
(2008)
Adv Exp Med Biol
, vol.606
, pp. 217-240
-
-
Hallgren, O.1
Aits, S.2
Brest, P.3
|