Changes in blood pressure and lipid levels in young women consuming a vitamin D-fortified skimmed milk: A randomised controlled trial

Nutrients

Volumn 5, Issue 12, 2013, Pages 4966-4977

  Toxqui, Laura ^a   Blanco Rojo, Ruth ^a   Wright, Ione ^a   Pérez Granados, Ana M ^a   Pilar Vaquero, M ^a  

^a INSTITUTE OF FOOD SCIENCE   (Spain)

Author keywords

Blood pressure; Cholesterol; Dairy product; Food fortification; Randomized controlled trial; Vitamin D; Women

Indexed keywords

25 HYDROXYVITAMIN D; CHOLESTEROL; COLECALCIFEROL; FERRIC PYROPHOSPHATE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MONOUNSATURATED FATTY ACID; PLACEBO; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; SUCRALOSE; SUGAR; TRIACYLGLYCEROL; VITAMIN D;

ADULT; ANTHROPOMETRIC PARAMETERS; ARTICLE; BLOOD PRESSURE VARIABILITY; BODY MASS; BODY WEIGHT; CALORIC INTAKE; CONTROLLED STUDY; DAIRY PRODUCT; DIASTOLIC BLOOD PRESSURE; DIETARY INTAKE; DOUBLE BLIND PROCEDURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FERRITIN BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; IRON STORAGE; LIPID BLOOD LEVEL; MASS SPECTROMETRY; MILK; NORMAL HUMAN; NUTRITIONAL ASSESSMENT; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE;

ADOLESCENT; ADULT; ANIMALS; ANTHROPOMETRY; BLOOD GLUCOSE; BLOOD PRESSURE; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; FOOD, FORTIFIED; HUMANS; IRON, DIETARY; MILK; QUESTIONNAIRES; TRIGLYCERIDES; VITAMIN D; YOUNG ADULT;

EID: 84889605202     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu5124966     Document Type: Article

References (44)

1. Jorde, R.; Grimnes, G. Vitamin D and metabolic health with special reference to the effect of vitamin D on serum lipids. Prog. Lipid Res. 2011, 50, 303-312.
2. Bikle, D. Nonclassic actions of vitamin D. J. Clin. Endocrinol. Metab. 2009, 94, 26-34.
3. Zhang, R.; Naughton, D.P. Vitamin D in health and disease: Current perspectives. Nutr. J. 2010, 9, 65.
4. Leu, M.; Giovannucci, E. Vitamin D: Epidemiology of cardiovascular risks and events. Best Pract. Res. Clin. Endocrinol. Metab. 2011, 25, 633-646.
5. Wang, T.J.; Pencina, M.J.; Booth, S.L.; Jacques, P.F.; Ingelsson, E.; Lanier, K.; Benjamin, E.J.; D'Agostino, R.B.; Wolf, M.; Vasan, R.S. Vitamin D deficiency and risk of cardiovascular disease. Circulation 2008, 117, 503-511.
6. Saliba, W.; Barnett, O.; Rennert, H.S.; Rennert, G. The risk of all-cause mortality is inversely related to serum 25(OH)D levels. J. Clin. Endocrinol. Metab. 2012, 97, 2792-2798.
7. Jorde, R.; Figenschau, Y.; Hutchinson, M.; Emaus, N.; Grimnes, G. High serum 25-hydroxyvitamin D concentrations are associated with a favorable serum lipid profile. Eur. J. Clin. Nutr. 2010, 64, 1457-1464.
8. Melamed, M.L.; Michos, E.D.; Post, W.; Astor, B. 25-Hydroxyvitamin D levels and the risk of mortality in the general population. Arch. Intern. Med. 2008, 168, 1629-1637.
9. Vaidya, A.; Forman, J.P. Vitamin D and hypertension: Current evidence and future directions. Hypertension 2010, 56, 774-779.
10. Pittas, A.G.; Lau, J.; Hu, F.B.; Dawson-Hughes, B. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J. Clin. Endocrinol. Metab. 2007, 92, 2017-2029.
11. Wang, H.; Xia, N.; Yang, Y.; Peng, D.Q. Influence of vitamin D supplementation on plasma lipid profiles: A meta-analysis of randomized controlled trials. Lipids Health Dis. 2012, 11, 42.
12. Sim, J.J.; Lac, P.T.; Liu, I.L.; Meguerditchian, S.O.; Kumar, V.A.; Kujubu, D.A.; Rasgon, S.A. Vitamin D deficiency and anemia: A cross-sectional study. Ann. Hematol. 2010, 89, 447-452.
13. Wright, I.; Blanco-Rojo, R.; Fernandez, M.C.; Toxqui, L.; Moreno, G.; Perez-Granados, A.M.; de la Piedra, C.; Remacha, A.F.; Vaquero, M.P. Bone remodelling is reduced by recovery from iron-deficiency anaemia in premenopausal women. J. Physiol. Biochem. 2013, 69, 889-896.
14. Toxqui, L.; Perez-Granados, A.M.; Blanco-Rojo, R.; Wright, I.; Gonzalez-Vizcayno, C.; Vaquero, M.P. Effects of an iron or iron-vitamin D fortified flavored skimmed milk on iron metabolism: A randomized controlled double-blind trial in iron-deficient women. J. Am. Coll. Nutr. 2013, 32, 312-320.
15. FESNAD. Ingestas Dietéticas de Referencia (IDR) para la Población Española. Act. Diet. 2010, 14, 196-197 (in Spanish).
16. Cuervo, M.; Corbalan, M.; Baladia, E.; Cabrerizo, L.; Formiguera, X.; Iglesias, C.; Lorenzo, H.; Polanco, I.; Quiles, J.; Romero de Avila, M.D., et al. Comparison of dietary reference intakes (DRI) between different countries of the European Union, The United States and the World Health Organization. Nutr. Hosp. 2009, 24, 384-414 (in Spanish).
17. Ross, A.C.; Taylor, C.L.; Yaktine, A.L.; Del Valle, H.B. Dietary Reference Intakes for Calcium Vitamin D; The National Academic Press: Washington, DC, USA, 2011.
18. González-Molero, I.; Morcillo, S.; Valdés, S.; Pérez-Valero, V.; Botas, P.; Delgado, E.; Hernández, D.; Olveira, G.; Rojo, G.; Gutierrez-Repiso, C., et al. Vitamin D deficiency in Spain: A population-based cohort study. Eur. J. Clin. Nutr. 2011, 65, 321-328.
19. Holick, M.F. Vitamin D deficiency. N. Engl. J. Med. 2007, 357, 266-281.
20. Calvo, M.S.; Whiting, S.J. Survey of current vitamin D food fortification practices in the United States and Canada. J. Steroid Biochem. Mol. Biol. 2013, 136, 211-213.
21. Schulz, K.F.; Altman, D.G.; Moher, D. CONSORT 2010 statement: Updated guidelines for reporting parallel group randomized trials. Ann. Intern. Med. 2010, 152, 726-732.
22. Institute of Medicine. Iron. In Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc; Institute of Medicine's Food and Nutrition Board, Ed.; National Academic Press: Washington, DC, USA, 2001; pp. 290-393.
23. Toxqui, L.; Perez-Granados, A.M.; Blanco-Rojo, R.; Wright, I.; de la Piedra, C.; Vaquero, M.P. Low iron status as a factor of increased bone resorption and effects of an iron and vitamin D-fortified skimmed milk on bone remodelling in young Spanish women. Eur. J. Nutr. 2013, in press.
24. Christakos, S.; Hewison, M.; Gardner, D.G.; Wagner, C.L.; Sergeev, I.N.; Rutten, E.; Pittas, A.G.; Boland, R.; Ferrucci, L.; Bikle, D.D. Vitamin D: Beyond bone. Ann. N. Y. Acad. Sci. 2013, 1287, 45-58.
25. George, P.S.; Pearson, E.R.; Witham, M.D. Effect of vitamin D supplementation on glycaemic control and insulin resistance: A systematic review and meta-analysis. Diabet. Med. 2012, 29, e142-e150.
26. Gaddipati, V.C.; Bailey, B.A.; Kuriacose, R.; Copeland, R.J.; Manning, T.; Peiris, A.N. The relationship of vitamin D status to cardiovascular risk factors and amputation risk in veterans with peripheral arterial disease. J. Am. Med. Dir. Assoc. 2011, 12, 58-61.
27. Karhapaa, P.; Pihlajamaki, J.; Porsti, I.; Kastarinen, M.; Mustonen, J.; Niemela, O.; Kuusisto, J. Diverse associations of 25-hydroxyvitamin D and 1,25-dihydroxy-vitamin D with dyslipidaemias. J. Intern. Med. 2010, 268, 604-610.
28. McLachlan, C.N. β-Casein A1, ischaemic heart disease mortality, and other illnesses. Med. Hypotheses 2001, 56, 262-272.
29. Tailford, K.A.; Berry, C.L.; Thomas, A.C.; Campbell, J.H. A casein variant in cows milk is atherogenic. Atherosclerosis 2003, 170, 13-19.
30. Giovannucci, E.; Liu, Y.; Hollis, B.W.; Rimm, E.B. 25-Hydroxyvitamin D and risk of myocardial infarction in men: A prospective study. Arch. Intern. Med. 2008, 168, 1174-1180.
31. Delvin, E.E.; Lambert, M.; Levy, E.; O'Loughlin, J.; Mark, S.; Gray-Donald, K.; Paradis, G. Vitamin D status is modestly associated with glycemia and indicators of lipid metabolism in French-Canadian children and adolescents. J. Nutr. 2010, 140, 987-991.
32. Ponda, M.P.; Dowd, K.; Finkielstein, D.; Holt, P.R.; Breslow, J.L. The short-term effects of vitamin D repletion on cholesterol: A randomized, placebo-controlled trial. Arterioscler. Thromb. Vasc. Biol. 2012, 32, 2510-2515.
33. Rice, B.H.; Cifelli, C.J.; Pikosky, M.A.; Miller, G.D. Dairy components and risk factors for cardiometabolic syndrome: Recent evidence and opportunities for future research. Adv. Nutr. 2011, 2, 396-407.
34. Wang, L.; Manson, J.E.; Buring, J.E.; Lee, I.M.; Sesso, H.D. Dietary intake of dairy products, calcium, and vitamin D and the risk of hypertension in middle-aged and older women. Hypertension 2008, 51, 1073-1079.
35. Alonso, A.; Beunza, J.J.; Delgado-Rodriguez, M.; Martinez, J.A.; Martinez-Gonzalez, M.A. Low-fat dairy consumption and reduced risk of hypertension: The Seguimiento Universidad de Navarra (SUN) cohort. Am. J. Clin. Nutr. 2005, 82, 972-979.
36. He, J.; Wofford, M.R.; Reynolds, K.; Chen, J.; Chen, C.S.; Myers, L.; Minor, D.L.; Elmer, P.J.; Jones, D.W.; Whelton, P.K. Effect of dietary protein supplementation on blood pressure: A randomized, controlled trial. Circulation 2011, 124, 589-595.
37. Pal, S.; Ellis, V. The chronic effects of whey proteins on blood pressure, vascular function, and inflammatory markers in overweight individuals. Obesity 2010, 18, 1354-1359.
38. Li, Y.C. Vitamin D regulation of the renin-angiotensin system. J. Cell. Biochem. 2003, 88, 327-331.
39. Tomaschitz, A.; Pilz, S.; Ritz, E.; Grammer, T.; Drechsler, C.; Boehm, B.O.; Marz, W. Independent association between 1,25-dihydroxyvitamin D, 25-hydroxyvitamin D and the renin-angiotensin system: The Ludwigshafen Risk and Cardiovascular Health (LURIC) study. Clin. Chim. Acta 2010, 411, 1354-1360.
40. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the substantiation of health claims related to vitamin D and maintenance of bone and teeth (ID 150, 151, 158), absorption and utilisation of calcium and phosphorus and maintenance of normal blood calcium concentrations (ID 152, 157), cell division (ID 153), and thyroid function (ID 156) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 2009, 7, 1227.
41. Wilson, P.W.; D'Agostino, R.B.; Levy, D.; Belanger, A.M.; Silbershatz, H.; Kannel, W.B. Prediction of coronary heart disease using risk factor categories. Circulation 1998, 97, 1837-1847.
42. National Heart Lung and Blood Institue. Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III); National Institutes of Health: Bethesda, MD, USA, 2002.
43. Perk, J.; de Backer, G.; Gohlke, H.; Graham, I.; Reiner, Z.; Verschuren, M.; Albus, C.; Benlian, P.; Boysen, G.; Cifkova, R., et al. European guidelines on cardiovascular disease prevention in clinical practice (version 2012). The fifth joint task force of the european society of cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). Eur. Heart J. 2012, 33, 1635-1701.
44. Moller, U.K.; Streym, S.V.; Jensen, L.T.; Mosekilde, L.; Schoenmakers, I.; Nigdikar, S.; Rejnmark, L. Increased plasma concentrations of vitamin D metabolites and vitamin D binding protein in women using hormonal contraceptives: A cross-sectional study. Nutrients 2013, 5, 3470-3480.