Perlecan domain v inhibits amyloid-β Induced brain endothelial cell toxicity and restores angiogenic function

Journal of Alzheimer's Disease

Volumn 38, Issue 2, 2014, Pages 415-423

  Parham, Christi ^a   Auckland, Lisa ^a   Rachwal, Jessica ^a   Clarke, Douglas ^a   Bix, Gregory ^b  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer's disease; amyloid 25 35; blood brain barrier; extracellular matrix; integrins; perlecan

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; INTEGRIN RECEPTOR; MATRIGEL; PERLECAN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; VERY LATE ACTIVATION ANTIGEN 5;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; BRAIN CELL; CELL ADHESION; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; IN VITRO STUDY; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; REDUCTION;

ALZHEIMER'S DISEASE; AMYLOID-$\BETA _{25-35}$; BLOOD-BRAIN BARRIER; EXTRACELLULAR MATRIX; INTEGRINS; PERLECAN;

AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; CELL DEATH; CELL LINE; CELL PROLIFERATION; DRUG INTERACTIONS; ENDOTHELIAL CELLS; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; MICE; MICE, INBRED C57BL; OLIGOSACCHARIDES; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING;

EID: 84889605157     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-130683     Document Type: Article

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