Alzheimer's β-amyloid peptide blocks vascular endothelial growth factor mediated signaling via direct interaction with VEGFR-2

Journal of Neurochemistry

Volumn 112, Issue 1, 2010, Pages 66-76

  Patel, Nikunj S ^a,b   Mathura, Venkatarajan S ^a   Bachmeier, Corbin ^a   Beaulieu Abdelahad, David ^a   Laporte, Vincent ^a   Weeks, Ophelia ^b   Mullan, Michael ^a   Paris, Daniel ^a  

^a ROSKAMP INSTITUTE   (United States)

^b FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

Alzheimer; Amyloid; Angiogenesis; Endothelial; Growth factor

Indexed keywords

AKT1 PROTEIN; AMYLOID BETA PROTEIN[1-42]; PROTEIN KINASE B; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN 165; VASCULOTROPIN RECEPTOR 2;

ALZHEIMER DISEASE; ANGIOGENESIS; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; BINDING COMPETITION; BLOOD BRAIN BARRIER; CELL FREE SYSTEM; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SENILE PLAQUE; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANGIOGENESIS INHIBITORS; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMANS; MICE; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PROTEIN BINDING; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 71649093560     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06426.x     Document Type: Article

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