Castration of male C57L/J mice increases susceptibility and estrogen treatment restores resistance to Theiler's virus-induced demyelinating disease

Journal of Neuroscience Research

Volumn 85, Issue 4, 2007, Pages 871-881

  Fuller, Alyson ^a   Yahikozawa, Hiroyuki ^a,d   Eui, Young So ^a   Dal Canto, Mauro ^a   Koh, Chang Sung ^b   Welsh, C Jane ^c   Kim, Byung S ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b SHINSHU UNIVERSITY   (Japan)

^c TEXAS A AND M UNIVERSITY   (United States)

^d NAGANO RED CROSS HOSPITAL   (Japan)

Author keywords

CNS; Demyelination; Estrogen; Infiltration; Viral

Indexed keywords

ESTROGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SEX HORMONE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ARTICLE; CASTRATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEMYELINATING DISEASE; DISEASE PREDISPOSITION; ENDOTHELIUM CELL; GLIA CELL; IMMUNE RESPONSE; IN VITRO STUDY; MACROPHAGE; MALE; MICROGLIA; MOUSE; MURINE ENCEPHALOMYELITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; VIRUS REPLICATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; CASTRATION; CELL PROLIFERATION; CYTOKINES; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; ENDOTHELIAL CELLS; ESTROGENS; FLOW CYTOMETRY; GENE EXPRESSION; MALE; MICE; MICE, INBRED C57BL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; THEILOVIRUS; TIME FACTORS;

EID: 33947238410     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21184     Document Type: Article

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