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Volumn 5, Issue 12, 2013, Pages 1313-1322

Employing an IL-23 p19 vaccine to block IL-23 ameliorates chronic murine colitis

Author keywords

Crohns disease; IL 23; inflammatory bowel disease; TNBS induced colitis; vaccine

Indexed keywords

HEPATITIS B CORE ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 23 P19 VACCINE; UNCLASSIFIED DRUG; VACCINE;

EID: 84889601193     PISSN: 1750743X     EISSN: 17507448     Source Type: Journal    
DOI: 10.2217/imt.13.141     Document Type: Article
Times cited : (11)

References (35)
  • 2
    • 79959216005 scopus 로고    scopus 로고
    • Genetics and pathogenesis of inflammatory bowel disease
    • Khor B, Gardet A, Xavier RJ. Genetics and pathogenesis of inflammatory bowel disease. Nature 474(7351), 307-317 (2011)
    • (2011) Nature 474 , vol.7351 , pp. 307-317
    • Khor, B.1    Gardet, A.2    Xavier, R.J.3
  • 4
    • 79955563439 scopus 로고    scopus 로고
    • Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases
    • Strober W, Fuss IJ. Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases. Gastroenterology 140(6), 1756-1767 (2011)
    • (2011) Gastroenterology , vol.140 , Issue.6 , pp. 1756-1767
    • Strober, W.1    Fuss, I.J.2
  • 5
    • 34047178588 scopus 로고    scopus 로고
    • Cytokine therapy for Crohn's disease: Advances in translational research
    • DOI 10.1146/annurev.med.58.121205.100607
    • Pizarro TT, Cominelli F. Cytokine therapy for Crohn's disease: advances in translational research. Annu. Rev. Med. 58, 433-444 (2007) (Pubitemid 46706525)
    • (2007) Annual Review of Medicine , vol.58 , pp. 433-444
    • Pizarro, T.T.1    Cominelli, F.2
  • 6
    • 33846036986 scopus 로고    scopus 로고
    • A master regulator in Crohn disease
    • Neurath MF. IL23: a master regulator in Crohn disease. Nat. Med. 13(1), 26-28 (2007)
    • (2007) Nat. Med , vol.13 , Issue.1 , pp. 26-28
    • Neurath, M.F.1
  • 7
    • 0030995575 scopus 로고    scopus 로고
    • Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
    • DOI 10.1016/S0016-5085(97)70128-8
    • Monteleone G, Biancone L, Marasco R et al. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 112(4), 1169-1178 (1997) (Pubitemid 27157528)
    • (1997) Gastroenterology , vol.112 , Issue.4 , pp. 1169-1178
    • Monteleone, G.1    Biancone, L.2    Marasco, R.3    Morrone, G.4    Marasco, O.5    Luzza, F.6    Pallone, F.7
  • 8
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • Neurath MF, Fuss I, Kelsall BL, Stuber E, Strober W. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J. Exp. Med. 182(5), 1281-1290 (1995)
    • (1995) J. Exp. Med , vol.182 , Issue.5 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Stuber, E.4    Strober, W.5
  • 9
    • 0033638507 scopus 로고    scopus 로고
    • Novel P19 Protein Engages IL12p40 to Form A Cytokine IL23, with biological activities similar as well as distinct from IL12
    • Oppmann B, Lesley R, Blom B et al. Novel p19 protein engages IL12p40 to form a cytokine, IL23, with biological activities similar as well as distinct from IL12. Immunity 13(5), 715-725 (2000)
    • (2000) Immunity , vol.13 , Issue.5 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3
  • 10
    • 33646397611 scopus 로고    scopus 로고
    • IL 23 is essential for T cell-mediated colitis and promotes inflammation via IL17 and IL 6
    • Yen D, Cheung J, Scheerens H et al. IL23 is essential for T cell-mediated colitis and promotes inflammation via IL17 and IL6. J. Clin. Invest. 116(5), 1310-1316 (2006)
    • (2006) J Clin Invest , vol.116 , Issue.5 , pp. 1310-1316
    • Yen, D.1    Cheung, J.2    Scheerens, H.3
  • 11
    • 33644774565 scopus 로고    scopus 로고
    • Evolving knowledge and therapy of inflammatory bowel disease
    • DOI 10.1038/nrd1986, PII N1986
    • Korzenik JR, Podolsky DK. Evolving knowledge and therapy of inflammatory bowel disease. Nat. Rev. Drug Discov. 5(3), 197-209 (2006) (Pubitemid 43336033)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.3 , pp. 197-209
    • Korzenik, J.R.1    Podolsky, D.K.2
  • 14
  • 15
    • 77955890952 scopus 로고    scopus 로고
    • Interleukin-23 drives intestinal inflammation through direct activity on T cells
    • Ahern PP, Schiering C, Buonocore S et al. Interleukin-23 drives intestinal inflammation through direct activity on T cells. Immunity 33(2), 279-288 (2010)
    • (2010) Immunity , vol.33 , Issue.2 , pp. 279-288
    • Ahern, P.P.1    Schiering, C.2    Buonocore, S.3
  • 18
    • 84865547366 scopus 로고    scopus 로고
    • Targeting IL23 by employing a p40 peptide-based vaccine ameliorates murine allergic skin and airway inflammation
    • Guan Q, Ma Y, Aboud L et al. Targeting IL23 by employing a p40 peptide-based vaccine ameliorates murine allergic skin and airway inflammation. Clin. Exp. Allergy 42(9), 1397-1405 (2012)
    • (2012) Clin. Exp. Allergy , vol.42 , Issue.9 , pp. 1397-1405
    • Guan, Q.1    Ma, Y.2    Aboud, L.3
  • 19
    • 35748966435 scopus 로고    scopus 로고
    • Anti-IL-17A autovaccination prevents clinical and histological manifestations of experimental autoimmune encephalomyelitis
    • DOI 10.1196/annals.1423.035, Autoimmunity, Part B Novel Applications of Basic Research
    • Uyttenhove C, Sommereyns C, Theate I, Michiels T, Van Snick J. Anti-IL17A autovaccination prevents clinical and histological manifestations of experimental autoimmune encephalomyelitis. Ann. NY Acad. Sci. 1110, 330-336 (2007) (Pubitemid 350043022)
    • (2007) Annals of the New York Academy of Sciences , vol.1110 , pp. 330-336
    • Uyttenhove, C.1    Sommereyns, C.2    Theate, I.3    Michiels, T.4    Van Snick, J.5
  • 20
    • 77952514447 scopus 로고    scopus 로고
    • Active immunization to tumor necrosis factor-alpha is effective in treating chronic established inflammatory disease: A long-term study in a transgenic model of arthritis
    • Delavallee L, Semerano L, Assier E et al. Active immunization to tumor necrosis factor-alpha is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis. Arthritis Res. Ther. 11(6), R195 (2009)
    • (2009) Arthritis Res. Ther , vol.11 , Issue.6
    • Delavallee, L.1    Semerano, L.2    Assier, E.3
  • 22
    • 43649107676 scopus 로고    scopus 로고
    • Active immunization with IL1 displayed on virus-like particles protects from autoimmune arthritis
    • Spohn G, Keller I, Beck M, Grest P, Jennings GT, Bachmann MF. Active immunization with IL1 displayed on virus-like particles protects from autoimmune arthritis. Eur. J. Immunol. 38(3), 877-887 (2008)
    • (2008) Eur. J. Immunol , vol.38 , Issue.3 , pp. 877-887
    • Spohn, G.1    Keller, I.2    Beck, M.3    Grest, P.4    Jennings, G.T.5    Bachmann, M.F.6
  • 23
    • 79960736362 scopus 로고    scopus 로고
    • Targeting IL12/IL23 by employing a p40 peptide-based vaccine ameliorates TNBS-induced acute and chronic murine colitis
    • Guan Q, Ma Y, Hillman CL et al. Targeting IL12/IL23 by employing a p40 peptide-based vaccine ameliorates TNBS-induced acute and chronic murine colitis. Mol. Med. 17(7-8), 646-656 (2011)
    • (2011) Mol. Med , vol.17 , Issue.7-8 , pp. 646-656
    • Guan, Q.1    Ma, Y.2    Hillman, C.L.3
  • 25
    • 77952678563 scopus 로고    scopus 로고
    • Targeting TGF-beta1 by employing a vaccine ameliorates fibrosis in a mouse model of chronic colitis
    • Ma Y, Guan Q, Bai A et al. Targeting TGF-beta1 by employing a vaccine ameliorates fibrosis in a mouse model of chronic colitis. Inflamm. Bowel Dis. 16, 1040-1050 (2010)
    • (2010) Inflamm. Bowel Dis , vol.16 , pp. 1040-1050
    • Ma, Y.1    Guan, Q.2    Bai, A.3
  • 26
    • 70350574143 scopus 로고    scopus 로고
    • Development of recombinant vaccines against IL12/IL23 p40 and in vivo evaluation of their effects in the downregulation of intestinal inflammation in murine colitis
    • Guan Q, Ma Y, Hillman CL et al. Development of recombinant vaccines against IL12/IL23 p40 and in vivo evaluation of their effects in the downregulation of intestinal inflammation in murine colitis. Vaccine 27(50), 7096-7104 (2009)
    • (2009) Vaccine , vol.27 , Issue.50 , pp. 7096-7104
    • Guan, Q.1    Ma, Y.2    Hillman, C.L.3
  • 27
    • 51249123523 scopus 로고    scopus 로고
    • Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody
    • Beyer BM, Ingram R, Ramanathan L et al. Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody. J. Mol. Biol. 382(4), 942-955 (2008)
    • (2008) J. Mol. Biol , vol.382 , Issue.4 , pp. 942-955
    • Beyer, B.M.1    Ingram, R.2    Ramanathan, L.3
  • 35
    • 80855131595 scopus 로고    scopus 로고
    • Active immunization against IL23p19 improves experimental arthritis
    • Ratsimandresy RA, Duvallet E, Assier E et al. Active immunization against IL23p19 improves experimental arthritis. Vaccine 29(50), 9329-9336 (2011)
    • (2011) Vaccine , vol.29 , Issue.50 , pp. 9329-9336
    • Ratsimandresy, R.A.1    Duvallet, E.2    Assier, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.