Immunogenicity of infliximab: How to handle the problem?

Acta Gastro-Enterologica Belgica

Volumn 70, Issue 2, 2007, Pages 163-170

  Baert, Filip ^b   De Vos, Martine ^b   Louis, Edouard ^b   Vermeire, Séverine ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ANTIBODY; ANTIHISTAMINIC AGENT; AZATHIOPRINE; CORTICOSTEROID; HYDROCORTISONE; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; METHOTREXATE; METHYLPREDNISOLONE; PARACETAMOL; PROMETHAZINE;

ADVERSE DRUG REACTION; ANTIBODY PRODUCTION; ARTICLE; CLINICAL PRACTICE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CROHN DISEASE; DRUG HYPERSENSITIVITY; DRUG RESPONSE; ENTERITIS; HEALTH SURVEY; HUMAN; IMMUNOGENICITY; IMMUNOSUPPRESSIVE TREATMENT; INFUSION REACTION; INFUSION SYSTEM; LONG TERM CARE; MAINTENANCE THERAPY; MONOTHERAPY; QUALITY OF LIFE;

ANTI-INFLAMMATORY AGENTS; ANTIBODIES; ANTIBODIES, MONOCLONAL; COLITIS, ULCERATIVE; CROHN DISEASE; HUMANS; IMMUNITY, CELLULAR; PROGNOSIS; RISK FACTORS;

EID: 34447519227     PISSN: 00015644     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. HANAUER S., WAGNER C., BALA M. et al. Incidence and importance of antibody responses to infliximab after maintenance of episodic treatment in Crohn's disease. Clin. Gastroenterol. Hepatol., 2004, 2 : 542-553.
2. PRESENT D.H., RUTGEERTS P., TARGAN S., HANAUER S.B., MAYER L., VAN HOGEZAND R.A., PODOLSKY D.K., SANDS B.E., BRAAKMAN T., DEWOODY K.L., SCHAIBLE T.F., VAN DEVENTER S.J. Infliximab for the treatment of fistulas in patients with Crohn's disease. N. Engl. J. Med., 1999, 340 : 1398-1405.
3. SANDS B.E., ANDERSON F.H., BERNSTEIN C.N. et al. Infliximab maintenance therapy for fistulizing Crohn's disease. N. Engl. J. Med., 2004, 350 : 876-85.
4. RUTGEERTS P., FEAGAN B.G., LICHTENSTEIN G.R., MAYER L.F., SCHREIBER S., COLOMBEL J.F., RACHMILEWITZ D., WOLF D.C., OLSON A., BAO W., HANAUER S.B. Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease. Gastroenterology, 2004, 126 : 402-13.