메뉴 건너뛰기




Volumn 104, Issue 12, 2013, Pages 1593-1599

Involvement of homologous recombination in the synergism between cisplatin and poly (ADP-ribose) polymerase inhibition

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINOBENZAMIDE; CISPLATIN; FLUOROURACIL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; RAD51 PROTEIN;

EID: 84889571439     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12281     Document Type: Article
Times cited : (25)

References (44)
  • 1
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers JH. Genome maintenance mechanisms for preventing cancer. Nature 2001; 411: 366-74.
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 2
    • 17244373777 scopus 로고    scopus 로고
    • Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
    • Farmer H, McCabe N, Lord CJ et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005; 434: 917-21.
    • (2005) Nature , vol.434 , pp. 917-921
    • Farmer, H.1    McCabe, N.2    Lord, C.J.3
  • 3
    • 0026507413 scopus 로고
    • Role of poly (ADP-ribose) formation in DNA repair
    • Satoh MS, Lindahl T. Role of poly (ADP-ribose) formation in DNA repair. Nature 1992; 356: 356-8.
    • (1992) Nature , vol.356 , pp. 356-358
    • Satoh, M.S.1    Lindahl, T.2
  • 4
    • 0028865245 scopus 로고
    • Post-translational modification of poly (ADP-ribose) polymerase induced by DNA strand breaks
    • Lindahl T, Satoh MS, Poirier GG, Klungland A. Post-translational modification of poly (ADP-ribose) polymerase induced by DNA strand breaks. Trends Biochem Sci 1995; 20: 405-11.
    • (1995) Trends Biochem Sci , vol.20 , pp. 405-411
    • Lindahl, T.1    Satoh, M.S.2    Poirier, G.G.3    Klungland, A.4
  • 5
    • 0033198919 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
    • D'Amours D, Desnoyers S, D'Silva I, Poirier GG. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem J 1999; 342: 249-68.
    • (1999) Biochem J , vol.342 , pp. 249-268
    • D'Amours, D.1    Desnoyers, S.2    D'Silva, I.3    Poirier, G.G.4
  • 6
    • 69849097500 scopus 로고    scopus 로고
    • PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination
    • Bryant HE, Petermann E, Schultz N et al. PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination. EMBO J 2009; 28: 2601-15.
    • (2009) EMBO J , vol.28 , pp. 2601-2615
    • Bryant, H.E.1    Petermann, E.2    Schultz, N.3
  • 7
    • 2342524565 scopus 로고    scopus 로고
    • Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks
    • Yang YG, Cortes U, Patnaik S, Jasin M, Wang ZQ. Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks. Oncogene 2004; 23: 3872-82.
    • (2004) Oncogene , vol.23 , pp. 3872-3882
    • Yang, Y.G.1    Cortes, U.2    Patnaik, S.3    Jasin, M.4    Wang, Z.Q.5
  • 8
    • 0344875495 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination
    • Schultz N, Lopez E, Saleh-Gohari N, Helleday T. Poly (ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination. Nucleic Acids Res 2003; 31: 4959-64.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4959-4964
    • Schultz, N.1    Lopez, E.2    Saleh-Gohari, N.3    Helleday, T.4
  • 9
    • 0035853295 scopus 로고    scopus 로고
    • DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells
    • Arnaudeau C, Lundin C, Helleday T. DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells. J Mol Biol 2001; 307: 1235-45.
    • (2001) J Mol Biol , vol.307 , pp. 1235-1245
    • Arnaudeau, C.1    Lundin, C.2    Helleday, T.3
  • 10
    • 84868221110 scopus 로고    scopus 로고
    • Trapping of PARP1 and PARP2 by clinical PARP inhibitors
    • Murai J, Huang SY, Das BB et al. Trapping of PARP1 and PARP2 by clinical PARP inhibitors. Cancer Res 2012; 72: 5588-99.
    • (2012) Cancer Res , vol.72 , pp. 5588-5599
    • Murai, J.1    Huang, S.Y.2    Das, B.B.3
  • 11
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • Hsiang YH, Lihou MG, Liu LF. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res 1989; 49: 5077-82.
    • (1989) Cancer Res , vol.49 , pp. 5077-5082
    • Hsiang, Y.H.1    Lihou, M.G.2    Liu, L.F.3
  • 12
    • 0023181174 scopus 로고
    • Topoisomerase II-mediated DNA breaks and cytotoxicity in relation to cell proliferation and the cell cycle in NIH 3T3 fibroblasts and L1210 leukemia cells
    • Markovits J, Pommier Y, Kerrigan D, Covey JM, Tilchen EJ, Kohn KW. Topoisomerase II-mediated DNA breaks and cytotoxicity in relation to cell proliferation and the cell cycle in NIH 3T3 fibroblasts and L1210 leukemia cells. Cancer Res 1987; 47: 2050-5.
    • (1987) Cancer Res , vol.47 , pp. 2050-2055
    • Markovits, J.1    Pommier, Y.2    Kerrigan, D.3    Covey, J.M.4    Tilchen, E.J.5    Kohn, K.W.6
  • 13
    • 0031032549 scopus 로고    scopus 로고
    • Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination
    • Sargent RG, Brenneman MA, Wilson JH. Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination. Mol Cell Biol 1997; 17: 267-77.
    • (1997) Mol Cell Biol , vol.17 , pp. 267-277
    • Sargent, R.G.1    Brenneman, M.A.2    Wilson, J.H.3
  • 14
    • 0025184272 scopus 로고
    • Inhibitor of poly (ADP-ribose)transferase potentiates the recombinogenic but not the mutagenic action of alkylating agents in somatic cells in vivo in Drosophila melanogaster
    • Magnusson J, Ramel C. Inhibitor of poly (ADP-ribose)transferase potentiates the recombinogenic but not the mutagenic action of alkylating agents in somatic cells in vivo in Drosophila melanogaster. Mutagenesis 1990; 5: 511-4.
    • (1990) Mutagenesis , vol.5 , pp. 511-514
    • Magnusson, J.1    Ramel, C.2
  • 15
    • 0026046440 scopus 로고
    • Stimulation of intrachromosomal homologous recombination in mammalian cells by an inhibitor of poly(ADP-ribosylation)
    • Waldman AS, Waldman BC. Stimulation of intrachromosomal homologous recombination in mammalian cells by an inhibitor of poly(ADP-ribosylation). Nucleic Acids Res 1991; 19: 5943-7.
    • (1991) Nucleic Acids Res , vol.19 , pp. 5943-5947
    • Waldman, A.S.1    Waldman, B.C.2
  • 16
    • 0029000890 scopus 로고
    • A dominant-negative mutant of human poly (ADP-ribose) polymerase affects cell recovery, apoptosis and sister chromatid exchange following DNA damage
    • Schreiber V, Hunting D, Trucco C et al. A dominant-negative mutant of human poly (ADP-ribose) polymerase affects cell recovery, apoptosis and sister chromatid exchange following DNA damage. Proc Natl Acad Sci USA 1995; 92: 4753-7.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4753-4757
    • Schreiber, V.1    Hunting, D.2    Trucco, C.3
  • 17
    • 0033570903 scopus 로고    scopus 로고
    • Inhibition of poly (ADP-ribose)polymerase stimulates extrachromosomal homologous recombination in mouse Ltk-fibroblasts
    • Semionov A, Cournoyer D, Chow TY. Inhibition of poly (ADP-ribose)polymerase stimulates extrachromosomal homologous recombination in mouse Ltk-fibroblasts. Nucleic Acids Res 1999; 27: 4526-31.
    • (1999) Nucleic Acids Res , vol.27 , pp. 4526-4531
    • Semionov, A.1    Cournoyer, D.2    Chow, T.Y.3
  • 18
    • 34249006299 scopus 로고    scopus 로고
    • ABT-888, an orally active poly (ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models
    • Donawho CK, Luo Y, Luo Y et al. ABT-888, an orally active poly (ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models. Clin Cancer Res 2007; 13: 2728-37.
    • (2007) Clin Cancer Res , vol.13 , pp. 2728-2737
    • Donawho, C.K.1    Luo, Y.2    Luo, Y.3
  • 19
    • 60549117554 scopus 로고    scopus 로고
    • Discovery of the Poly (ADP-ribose) polymerase (PARP) inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the treatment of cancer
    • Penning TD, Zhu GD, Gandhi VB et al. Discovery of the Poly (ADP-ribose) polymerase (PARP) inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the treatment of cancer. J Med Chem 2009; 52: 514-23.
    • (2009) J Med Chem , vol.52 , pp. 514-523
    • Penning, T.D.1    Zhu, G.D.2    Gandhi, V.B.3
  • 20
    • 52449111109 scopus 로고    scopus 로고
    • Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin
    • Evers B, Drost R, Schut E et al. Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin. Clin Cancer Res 2008; 14: 3916-25.
    • (2008) Clin Cancer Res , vol.14 , pp. 3916-3925
    • Evers, B.1    Drost, R.2    Schut, E.3
  • 21
    • 65949095892 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase-1 inhibitor treatment regresses autochthonous Brca2/p53-mutant mammary tumors in vivo and delays tumor relapse in combination with carboplatin
    • Hay T, Matthews JR, Pietzka L et al. Poly (ADP-ribose) polymerase-1 inhibitor treatment regresses autochthonous Brca2/p53-mutant mammary tumors in vivo and delays tumor relapse in combination with carboplatin. Cancer Res 2009; 69: 3850-5.
    • (2009) Cancer Res , vol.69 , pp. 3850-3855
    • Hay, T.1    Matthews, J.R.2    Pietzka, L.3
  • 22
    • 54549103449 scopus 로고    scopus 로고
    • 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly (ADP-ribose) polymerase-1
    • Menear KA, Adcock C, Boulter R et al. 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly (ADP-ribose) polymerase-1. J Med Chem 2008; 51: 6581-91.
    • (2008) J Med Chem , vol.51 , pp. 6581-6591
    • Menear, K.A.1    Adcock, C.2    Boulter, R.3
  • 23
    • 55949092708 scopus 로고    scopus 로고
    • High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
    • Rottenberg S, Jaspers JE, Kersbergen A et al. High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs. Proc Natl Acad Sci USA 2008; 105: 17079-84.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 17079-17084
    • Rottenberg, S.1    Jaspers, J.E.2    Kersbergen, A.3
  • 24
    • 70949086814 scopus 로고    scopus 로고
    • Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly (ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors
    • Jones P, Altamura S, Boueres J et al. Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly (ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. J Med Chem 2009; 52: 7170-85.
    • (2009) J Med Chem , vol.52 , pp. 7170-7185
    • Jones, P.1    Altamura, S.2    Boueres, J.3
  • 25
    • 77953373821 scopus 로고    scopus 로고
    • Sensitization to radiation and alkylating agents by inhibitors of poly (ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair
    • Löser DA, Shibata A, Shibata AK, Woodbine LJ, Jeggo PA, Chalmers AJ. Sensitization to radiation and alkylating agents by inhibitors of poly (ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair. Mol Cancer Ther 2010; 9: 1775-87.
    • (2010) Mol Cancer Ther , vol.9 , pp. 1775-1787
    • Löser, D.A.1    Shibata, A.2    Shibata, A.K.3    Woodbine, L.J.4    Jeggo, P.A.5    Chalmers, A.J.6
  • 27
    • 0038441637 scopus 로고    scopus 로고
    • Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma
    • Shimada H, Nabeya Y, Okazumi S et al. Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma. Surgery 2003; 133: 486-94.
    • (2003) Surgery , vol.133 , pp. 486-494
    • Shimada, H.1    Nabeya, Y.2    Okazumi, S.3
  • 28
    • 0033061496 scopus 로고    scopus 로고
    • Phase II trial of 5-fluorouracil and low-dose cisplatin in patients with squamous cell carcinoma of the esophagus
    • Sekiguchi H, Akiyama S, Fujiwara M et al. Phase II trial of 5-fluorouracil and low-dose cisplatin in patients with squamous cell carcinoma of the esophagus. Surg Today 1999; 29: 97-101.
    • (1999) Surg Today , vol.29 , pp. 97-101
    • Sekiguchi, H.1    Akiyama, S.2    Fujiwara, M.3
  • 29
    • 0022886092 scopus 로고
    • Biochemical basis for cisplatin and 5-fluorouracil synergism in human ovarian carcinoma cells
    • Scanlon KJ, Newman EM, Lu Y, Priest DG. Biochemical basis for cisplatin and 5-fluorouracil synergism in human ovarian carcinoma cells. Proc Natl Acad Sci USA 1986; 83: 8923-5.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 8923-8925
    • Scanlon, K.J.1    Newman, E.M.2    Lu, Y.3    Priest, D.G.4
  • 30
    • 40649089058 scopus 로고    scopus 로고
    • Oesophagectomy after definitive chemoradiation in patients with locally advanced oesophageal cancer
    • Borghesi S, Hawkins MA, Tait D. Oesophagectomy after definitive chemoradiation in patients with locally advanced oesophageal cancer. Clin Oncol (R Coll Radiol) 2008; 20: 221-6.
    • (2008) Clin Oncol (R Coll Radiol) , vol.20 , pp. 221-226
    • Borghesi, S.1    Hawkins, M.A.2    Tait, D.3
  • 31
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2-deficient tumours with inhibitors of poly (ADP-ribose) polymerase
    • Bryant HE, Schultz N, Thomas HD et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly (ADP-ribose) polymerase. Nature 2005; 434: 913-7.
    • (2005) Nature , vol.434 , pp. 913-917
    • Bryant, H.E.1    Schultz, N.2    Thomas, H.D.3
  • 32
    • 23344444636 scopus 로고    scopus 로고
    • Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
    • Saleh-Gohari N, Bryant HE, Schultz N, Parker KM, Cassel TN, Helleday T. Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol Cell Biol 2005; 25: 7158-69.
    • (2005) Mol Cell Biol , vol.25 , pp. 7158-7169
    • Saleh-Gohari, N.1    Bryant, H.E.2    Schultz, N.3    Parker, K.M.4    Cassel, T.N.5    Helleday, T.6
  • 33
    • 0029909565 scopus 로고    scopus 로고
    • A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53
    • Lim DS, Hasty P. A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol Cell Biol 1996; 16: 7133-43.
    • (1996) Mol Cell Biol , vol.16 , pp. 7133-7143
    • Lim, D.S.1    Hasty, P.2
  • 34
    • 0029987450 scopus 로고    scopus 로고
    • Targeted disruption of the Rad51 gene leads to lethality in embryonic mice
    • Tsuzuki T, Fujii Y, Sakumi K et al. Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc Natl Acad Sci USA 1996; 93: 6236-40.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6236-6240
    • Tsuzuki, T.1    Fujii, Y.2    Sakumi, K.3
  • 35
    • 0032518657 scopus 로고    scopus 로고
    • Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death
    • Sonoda E, Sasaki MS, Buerstedde JM et al. Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. EMBO J 1998; 17: 598-608.
    • (1998) EMBO J , vol.17 , pp. 598-608
    • Sonoda, E.1    Sasaki, M.S.2    Buerstedde, J.M.3
  • 36
    • 4944229642 scopus 로고    scopus 로고
    • Hallmarks of "BRCAness" in sporadic cancers
    • Turner N, Tutt A, Ashworth A. Hallmarks of "BRCAness" in sporadic cancers. Nat Rev Cancer 2004; 4: 814-9.
    • (2004) Nat Rev Cancer , vol.4 , pp. 814-819
    • Turner, N.1    Tutt, A.2    Ashworth, A.3
  • 37
    • 79953283583 scopus 로고    scopus 로고
    • The therapeutic ratio is preserved for radiotherapy or cisplatin treatment in BRCA2-mutated prostate cancers
    • Vesprini D, Narod SA, Trachtenberg J et al. The therapeutic ratio is preserved for radiotherapy or cisplatin treatment in BRCA2-mutated prostate cancers. Can Urol Assoc J 2011; 5: E31-5.
    • (2011) Can Urol Assoc J , vol.5
    • Vesprini, D.1    Narod, S.A.2    Trachtenberg, J.3
  • 38
    • 59449085305 scopus 로고    scopus 로고
    • Phase I study of the poly (ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors
    • Plummer R, Jones C, Middleton M et al. Phase I study of the poly (ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors. Clin Cancer Res 2008; 14: 7917-23.
    • (2008) Clin Cancer Res , vol.14 , pp. 7917-7923
    • Plummer, R.1    Jones, C.2    Middleton, M.3
  • 39
    • 84859864115 scopus 로고    scopus 로고
    • A phase I combination study of olaparib with cisplatin and gemcitabine in adults with solid tumors
    • Rajan A, Carter CA, Kelly RJ et al. A phase I combination study of olaparib with cisplatin and gemcitabine in adults with solid tumors. Clin Cancer Res 2012; 18: 2344-51.
    • (2012) Clin Cancer Res , vol.18 , pp. 2344-2351
    • Rajan, A.1    Carter, C.A.2    Kelly, R.J.3
  • 40
    • 77950974130 scopus 로고    scopus 로고
    • Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly (ADP-ribose) polymerase inhibitors
    • Mukhopadhyay A, Elattar A, Cerbinskaite A et al. Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly (ADP-ribose) polymerase inhibitors. Clin Cancer Res 2010; 16: 2344-51.
    • (2010) Clin Cancer Res , vol.16 , pp. 2344-2351
    • Mukhopadhyay, A.1    Elattar, A.2    Cerbinskaite, A.3
  • 41
    • 34447115757 scopus 로고    scopus 로고
    • Role for BLM in replication-fork restart and suppression of origin firing after replicative stress
    • Davies SL, North PS, Hickson ID. Role for BLM in replication-fork restart and suppression of origin firing after replicative stress. Nat Struct Mol 2007; 14: 677-9.
    • (2007) Nat Struct Mol , vol.14 , pp. 677-679
    • Davies, S.L.1    North, P.S.2    Hickson, I.D.3
  • 42
    • 76849109722 scopus 로고    scopus 로고
    • Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair
    • Petermann E, Orta ML, Issaeva N, Schultz N, Helleday T. Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair. Mol Cell 2010; 37: 492-502.
    • (2010) Mol Cell , vol.37 , pp. 492-502
    • Petermann, E.1    Orta, M.L.2    Issaeva, N.3    Schultz, N.4    Helleday, T.5
  • 44
    • 49249119415 scopus 로고    scopus 로고
    • A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair
    • Ashworth A. A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. J Clin Oncol 2008; 26: 3785-90.
    • (2008) J Clin Oncol , vol.26 , pp. 3785-3790
    • Ashworth, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.