High Content Analysis of Human Embryonic Stem Cell Growth and Differentiation

High Content Screening: Science, Techniques and Applications

Volumn , Issue , 2007, Pages 205-224

  Sammak, Paul J ^a   Abraham, Vivek ^b   Ghosh, Richik ^c   Haskins, Jeff ^c   Jane, Esther ^a   Petrosko, Patti ^a   Erb, Teresa M ^a   Kinney, Tia N ^a   Jefferys, Christopher ^d,e   Desai, Mukund ^d   Mangoubi, Rami ^d  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b Cellomics   (United States)

^c Cellomics Inc   (United States)

^d CHARLES STARK DRAPER LABORATORY   (United States)

^e Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Human embryonic stem cells (hESCs); Pluripotency, and cell proliferation and molecular analysis; Stem cell classification

Indexed keywords

EID: 84889385659     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470229866.ch9     Document Type: Chapter

References (62)

1. Carpenter MK, Rosler E, Rao MS. Characterization and differentiation of human embryonic stem cells. Cloning Stem Cells 2003;5(1):79-88.
2. Stoltz JF, et al. Cell and tissue engineering and clinical applications: an overview. Biomed. Mater. Eng. 2006;16(4 Suppl):S3-S18.
3. Caspi O, et al. Tissue engineering of vascularized cardiac muscle from human embryonic stem cells. Circ. Res. 2007;100(2):263-272.
4. Lavon N, Benvenisty N. Study of hepatocyte differentiation using embryonic stem cells. J. Cell Biochem. 2005;96(6):1193-2202.
5. Rambhatla L, et al. Generation of hepatocyte-like cells from human embryonic stem cells. Cell Transplant. 2003;12(1):1-11.
6. Schwartz RE, et al. Defined conditions for development of functional hepatic cells from human embryonic stem cells. Stem Cells Dev. 2005;14(6):643-655.
7. Foley A, Mercola M. Heart induction: embryology to cardiomyocyte regeneration. Trends Cardiovasc. Med. 2004;14(3):121-125.
8. Heng BC, et al. Strategies for directing the differentiation of stem cells into the cardiomyogenic lineage in vitro. Cardiovasc. Res. 2004;62(1):34-42.
9. Fijnvandraat AC, Lekanne Deprez RH, Moorman AF. Development of heart muscle-cell diversity: a help or a hindrance for phenotyping embryonic stem cell-derived cardiomyocytes. Cardiovasc. Res. 2003;58(2):303-312.
10. Xu C, et al. Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ. Res. 2002;91(6):501-508.
11. Lumelsky N, et al. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001;292(5520):1389-1394.
12. Levenberg S, et al. Endothelial cells derived from human embryonic stem cells. Proc. Natl Acad. Sci. USA 2002;99(7):4391-4396.
13. Munoz-Sanjuan I, Brivanlou AH. Neural induction, the default model and embryonic stem cells. Nat. Rev. Neurosci. 2002;3(4):271-280.
14. Gotz M, Barde YA. Radial glial cells defined and major intermediates between embryonic stem cells and CNS neurons. Neuron. 2005;46(3):369-372.
15. Perrier AL, et al. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc. Natl Acad. Sci. USA 2004;101(34):12543-12548.
16. Tabar V, et al. Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nature Biotechnology 2005;23(5):601-606.
17. Rao M. Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells. Dev. Biol. 2004;275(2):269-286.
18. Pera MF, Trounson AO. Human embryonic stem cells: prospects for development. Development 2004;131(22):5515-5525.
19. Meshorer E, et al. Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev. Cell 2006;10(1):105-116.
20. Azuara V, et al. Chromatin signatures of pluripotent cell lines. Nat. Cell. Biol. 2006;8(5):532-538.
21. Williams RR, et al. Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus. J. Cell. Sci. 2006;119(Pt 1):132-140.
22. Lee TI, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006;125(2):301-313.
23. Csoka AB, et al. Novel lamin A/C gene (LMNA) mutations in atypical progeroid syndromes. J. Med. Genet. 2004;41:304-308.
24. Constantinescu D, et al. Lamin A/C expression is a marker of mouse and human embryonic stem cell differentiation. Stem Cells 2006;24:117-185.
25. Wobus AM, Boheler KR. Embryonic stem cells: prospects for developmental biology and cell therapy. Physiol. Rev. 2005;85(2):635-678.
26. Chang KH, Zandstra PW. Quantitative screening of embryonic stem cell differentiation: endoderm formation as a model. Biotechnol. Bioeng. 2004;88(3):287-298.
27. Thomson JA, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282(5391):1145-1147.
28. Lavoir MC, Conaghan J, Pedersen RA. Culture of human embryos for studies on the derivation of human pluripotent cells: a preliminary investigation. Reprod. Fertil. Dev. 1998;10(7-8):557-561.
29. Amit M, et al. Human feeder layers for human embryonic stem cells. Biology of Reproduction 2003;68:2150-2156.
30. Hovatta O, et al. A culture system using human fibroblasts as feeder cells allows production of human embryonic stem cells. European Society of Human Reproduction and Embryology 2003;18(7):1404-1409.
31. Inzunza J, et al. Derivation of human embryonic stem cell lines in serum replacement medium using postnatal human fibroblasts as feeder cells. Stem Cells 2005;23:544-549.
32. Genbacev O, et al. Serum-free derivation of human embryonic stem cell lines on human placental fibroblast feeders. Fertil. Steril 2005;83(5):1517-1529.
33. Schatten G, et al. Culture of human embryonic stem cells. Nat. Methods 2005;2(6):455-463.
34. Shin S, et al. Long term proliferation of human embryonic stem cell-derived neuroepithelial cells using defined adherent culture conditions. Stem Cells 2006;29(1):125-138.
35. Ludwig TE, et al. Derivation of human embryonic stem cells in defined conditions. Nat. Biotechnol 2006;24(2):185-187.
36. Lu J, et al. Defined culture conditions of human embryonic stem cells. Proc. Natl. Acad. Sci. USA 2006;103(15):5688-5693.
37. Vallier L, Alexander M, Pedersen RA. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. J. Cell Sci. 2005;118(Pt 19): 4495-4509.
38. Ozolek JA, et al. Human embryonic stem cells (HSF-6) show greater proliferation and apoptoses when grown on glioblastoma cells than mouse embryonic fibroblasts at day 19 in culture: comparison of proliferation, survival, and neural differentiation on two different feeder cell types. Stem Cells and Development 2007;16(3):403-412.
39. Barberi T, et al. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat. Biotechnol. 2003;21(10):1200-1207.
40. Huang K, Murphy RF. Boosting accuracy of automated classification of fluorescence microscope images for location proteomics. BMC Bioinformatics 2004;5:78.
41. Rubegni P, et al. Differentiation between pigmented Spitz naevus and melanoma by digital dermoscopy and stepwise logistic discriminant analysis. Melanoma Res. 2001;11(1):37-44.
42. Handels H, et al. Feature selection for optimized skin tumor recognition using genetic algorithms. Artif. Intell. Med. 1999;16(3):283-297.
43. Gerger A, Pompl R, Smolle J. Automated epiluminescence microscopy-tissue counter analysis using CART and 1-NN in the diagnosis of melanoma. Skin. Res. Technol., 2003;9(2):105-110.
44. Rajpoot K, Rajpoot N, editors. Wavelet based segmentation of hyperspectral colon tissue imagery. 7th IEEE International Multitopic Conference; 2003 Dec 8-9; Islamabad, Pakistan: IEEE; 2003. p38-43.
45. Sivaramakrishna R, et al. Texture analysis of lesions in breast ultrasound images. Comput. Med. Imaging Graph. 2002;26(5):303-307.
46. Jeffreys C. Support vector machine and parmetric wavelet-based texture classification of stem cell images. Cambridge, Massachusetts: Massachusetts institute of Technology; 2004. Computer science.
47. Mangoubi RS, Jeffreys CG, Desai MN, Copeland A, Sammak PJ. Non-invasive image based support vector machine classification of human embryonic stem cells. Fourth IEEE International Symposium of Biomedical Imaging; 2007 April 12-15; Washington, DC: IEEE; 2007.
48. Do MN, Vetterli M.Wavelet-based texture retrieval using generalized Gaussian density and Kullback-Leibler distance. IEEE Transactions on Image Processing 2002;11(2):146-158.
49. Tuceryan M, Jain A. Texture analysis. In: Chen CH, Pau LF,Wang PSP, editors. The handbook of pattern recognition and computer vision. World Scientific Publishing Company; 1998. 207-248.
50. Haralick RM. Statistical and structural approaches to texture. Proceedings of the IEEE 1979;67:786-804.
51. Burges CJC. A tutorial on support vector machines for pattern recognition. Data Mining and Knowledge Discovery 1998;2:121-167.
52. Hubbard BB. The world according to wavelets: the story of a mathematical technique in the making. 2nd ed AK Peters Ltd; 1998.
53. Mallat SG. A wavelet tour of signal processing. Academic Press; 1998.
54. Ginis I, et al. Differences between human and mouse embryonic stem cells. Dev. Biol., 2004;269(2):360-380.
55. Carpenter MK, et al. Properties of four human embryonic stem cell lines maintained in a feeder-free culture system. Dev. Dyn. 2004;229(2):243-258.
56. Bhattacharya B, et al. Gene expression in human embryonic stem cell lines: unique molecular signature. Blood 2004;103(8):2956-2964.
57. Richards M, et al. Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nat. Biotechnol. 2002;20(9):933-936.
58. Pedersen RA. Embryonic stem cells for medicine. Sci. Am. 1999;280(4):68-73.
59. Rodda DJ, et al. Transcriptional regulation of nanog by OCT4 and SOX2. J. Biol. Chem. 2005;280(26):24731-24737.
60. Kuroda T, et al. Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol. Cell. Biol. 2005;25(6):2475-2485.
61. Taranger CK, et al. Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells. Mol. Biol. Cell 2005;16(12):5719-5735.
62. Yoshimizu T, et al. Germline-specific expression of the Oct-4/green fluorescent protein (GFP) transgene in mice. Dev. Growth Differ. 1999;41(6):675-684.