Application of Artificial Model Systems to Study the Interactions of Fluorinated Amino Acids within the Native Environment of Coiled Coil Proteins

Fluorine in Medicinal Chemistry and Chemical Biology

Volumn , Issue , 2009, Pages 389-409

  Salwiczek, Mario ^a   Vagt, Toni ^a   Koksch, Beate ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Antiparallel homodimeric model system; Artificial model system application; Artificial model systems studying interactions of fluorinated amino acids within native environment of coiled coil proteins; Do fluorine fluorine interactions interfere with coiled coil association and dissociation?; Effects of fluorination difficult to predict of spatial demand, hydrophobicity, and polarity on structural stability; Fluorinated analogues used as powerful analytical labels to investigate protein structure and protein ligand interactions; Helical wheel and sequence representation of antiparallel, dimeric model system; Hydrophobicity, spatial demand and polarity

Indexed keywords

EID: 84889282753     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781444312096.ch15     Document Type: Chapter

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