Inhibition of hepatitis C virus by the cyanobacterial protein microcystis viridis lectin: Mechanistic differences between the high-mannose specific lectins MVL, CV-N, and GNA

Molecular Pharmaceutics

Volumn 10, Issue 12, 2013, Pages 4590-4602

  Kachko, Alla ^a   Loesgen, Sandra ^b   Shahzad Ul Hussan, Syed ^b,c   Tan, Wendy ^a   Zubkova, Iryna ^a   Takeda, Kazuyo ^a   Wells, Frances ^a   Rubin, Steven ^a   Bewley, Carole A ^b   Major, Marian E ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

antiviral lectin; biolayer interferometry; cyanovirin N (CV N); HCV entry inhibitor; HCVcc; hepatitis C

Indexed keywords

ANTIVIRUS AGENT; CYANOVIRIN N; GALANTHUS NIVALIS AGGLUTININ; GLYCAN; MANNOSE BINDING LECTIN; MICROCYSTIS VIRIDIS LECTIN; PLANT LECTIN; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CONFOCAL MICROSCOPY; FLUORESCENCE ACTIVATED CELL SORTING; GALANTHUS; HEPATITIS C VIRUS; IC 50; INTERFEROMETRY; MICROCYSTIS; MICROCYSTIS VIRIDIS; NONHUMAN; PRIORITY JOURNAL; TARGET CELL; VIRUS INHIBITION; VIRUS PARTICLE;

ANTIVIRAL AGENTS; BACTERIAL PROTEINS; CARRIER PROTEINS; CELL LINE, TUMOR; CYANOBACTERIA; GLYCOPROTEINS; HEPACIVIRUS; HUMANS; MANNOSE-BINDING LECTINS; MICROCYSTIS; PLANT LECTINS; RECOMBINANT PROTEINS;

EID: 84889241787     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400399b     Document Type: Article

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