Rough titanium alloys regulate osteoblast production of angiogenic factors

Spine Journal

Volumn 13, Issue 11, 2013, Pages 1563-1570

  Olivares Navarrete, Rene ^a   Hyzy, Sharon L ^a   Gittens I, Rolando A ^b   Schneider, Jennifer M ^c   Haithcock, David A ^a   Ullrich, Peter F ^d   Slosar, Paul J ^e   Schwartz, Zvi ^a,f   Boyan, Barbara D ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b Georgia Institute of Technology   (United States)

^c Titan Spine LLC   (United States)

^d NeuroSpine Center of Wisconsin   (United States)

^e San Francisco Spine Institute   (United States)

^f UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Angiogenesis; Osteoblast; PEEK; Polyether ether ketone; Titanium aluminum vanadium alloy

Indexed keywords

ANGIOGENIC FACTOR; ANGIOPOIETIN 1; FIBROBLAST GROWTH FACTOR 2; INTEGRIN; MESSENGER RNA; OSTEOPROTEGERIN; POLYETHERETHERKETONE; TITANIUM; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; BONE GROWTH; BONE REGENERATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; OSSIFICATION; OSTEOBLAST; OSTEOCLAST ACTIVITY; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SPINE FUSION;

ANGIOGENESIS; OSTEOBLAST; PEEK; POLYETHER-ETHER-KETONE; TITANIUM-ALUMINUM-VANADIUM ALLOY;

ALLOYS; ANGIOPOIETIN-1; BIOCOMPATIBLE MATERIALS; CELL LINE; CELLS, CULTURED; FIBROBLAST GROWTH FACTOR 2; HUMANS; KETONES; OSTEOBLASTS; OSTEOPROTEGERIN; POLYETHYLENE GLYCOLS; TITANIUM; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84889094677     PISSN: 15299430     EISSN: 18781632     Source Type: Journal    
DOI: 10.1016/j.spinee.2013.03.047     Document Type: Article

References (48)

1. J.M. Toth, M. Wang, and B.T. Estes Polyetheretherketone as a biomaterial for spinal applications Biomaterials 27 2006 324 334
2. H.J. Bruner, Y. Guan, and N. Yoganandan Biomechanics of polyaryletherketone rod composites and titanium rods for posterior lumbosacral instrumentation. Presented at the 2010 Joint Spine Section Meeting. Laboratory investigation J Neurosurg Spine 13 2010 766 772
3. S.M. Kurtz, and J.N. Devine PEEK biomaterials in trauma, orthopedic, and spinal implants Biomaterials 28 2007 4845 4869
4. T.W. Bauer, and J. Schils The pathology of total joint arthroplasty. II. Mechanisms of implant failure Skeletal Radiol 28 1999 483 497
5. J.B. Brunski In vivo bone response to biomechanical loading at the bone/dental-implant interface Adv Dent Res 13 1999 99 119
6. V.F. Stenport, and C.B. Johansson Evaluations of bone tissue integration to pure and alloyed titanium implants Clin Implant Dent Relat Res 10 2008 191 199
7. D. De Leonardis, A.K. Garg, and G.E. Pecora Osseointegration of rough acid-etched titanium implants: 5-year follow-up of 100 minimatic implants Int J Oral Maxillofac Implants 14 1999 384 391
8. L. Linder Osseointegration of metallic implants. I. Light microscopy in the rabbit Acta Orthop Scand 60 1989 129 134
9. E.R. Santos, D.G. Goss, R.K. Morcom, and R.D. Fraser Radiologic assessment of interbody fusion using carbon fiber cages Spine 28 2003 997 1001
10. N.K. Anjarwalla, R.K. Morcom, and R.D. Fraser Supplementary stabilization with anterior lumbar intervertebral fusion - a radiologic review Spine 31 2006 1281 1287
11. J. Lincks, B.D. Boyan, and C.R. Blanchard Response of MG63 osteoblast-like cells to titanium and titanium alloy is dependent on surface roughness and composition Biomaterials 19 1998 2219 2232
12. Z. Schwartz, P. Raz, and G. Zhao Effect of micrometer-scale roughness of the surface of Ti6Al4V pedicle screws in vitro and in vivo J Bone Joint Surg Am 90 2008 2485 2498
13. B.D. Boyan, Z. Schwartz, and C.H. Lohmann Pretreatment of bone with osteoclasts affects phenotypic expression of osteoblast-like cells J Orthop Res 21 2003 638 647
14. J. Vlacic-Zischke, S.M. Hamlet, and T. Friis The influence of surface microroughness and hydrophilicity of titanium on the up-regulation of TGFbeta/BMP signalling in osteoblasts Biomaterials 32 2011 665 671
15. K. Kieswetter, Z. Schwartz, and T.W. Hummert Surface roughness modulates the local production of growth factors and cytokines by osteoblast-like MG-63 cells J Biomed Mater Res 32 1996 55 63
16. Z. Schwartz, R. Olivares-Navarrete, and M. Wieland Mechanisms regulating increased production of osteoprotegerin by osteoblasts cultured on microstructured titanium surfaces Biomaterials 30 2009 3390 3396
17. L. Geris, A. Gerisch, and J.V. Sloten Angiogenesis in bone fracture healing: a bioregulatory model J Theor Biol 251 2008 137 158
18. C.L. Duvall, W.R. Taylor, and D. Weiss Impaired angiogenesis, early callus formation, and late stage remodeling in fracture healing of osteopontin-deficient mice J Bone Miner Res 22 2007 286 297
19. K. Abshagen, I. Schrodi, T. Gerber, and B. Vollmar In vivo analysis of biocompatibility and vascularization of the synthetic bone grafting substitute NanoBone J Biomed Mater Res A 91 2009 557 566
20. L. Schweigerer, G. Neufeld, and J. Friedman Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth Nature 325 1987 257 259
21. D.T. Connolly, D.M. Heuvelman, and R. Nelson Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis J Clin Invest 84 1989 1470 1478
22. V.B. Mehta, and G.E. Besner HB-EGF promotes angiogenesis in endothelial cells via PI3-kinase and MAPK signaling pathways Growth Factors 25 2007 253 263
23. A.L. Raines, R. Olivares-Navarrete, and M. Wieland Regulation of angiogenesis during osseointegration by titanium surface microstructure and energy Biomaterials 31 2010 4909 4917
24. K. Anselme, and M. Bigerelle Topography effects of pure titanium substrates on human osteoblast long-term adhesion Acta Biomater 1 2005 211 222
25. K. Anselme, M. Bigerelle, and B. Noel Qualitative and quantitative study of human osteoblast adhesion on materials with various surface roughnesses J Biomed Mater Res 49 2000 155 166
26. R. Olivares-Navarrete, P. Raz, and G. Zhao Integrin alpha2beta1 plays a critical role in osteoblast response to micron-scale surface structure and surface energy of titanium substrates Proc Natl Acad Sci U S A 105 2008 15767 15772
27. P. Raz, C.H. Lohmann, and J. Turner 1Alpha,25(OH)2D3 regulation of integrin expression is substrate dependent J Biomed Mater Res A 71 2004 217 225
28. M.C. Siebers, P.J. ter Brugge, X.F. Walboomers, and J.A. Jansen Integrins as linker proteins between osteoblasts and bone replacing materials. A critical review Biomaterials 26 2005 137 146
29. B.D. Boyan, C.H. Lohmann, and M. Sisk Both cyclooxygenase-1 and cyclooxygenase-2 mediate osteoblast response to titanium surface roughness J Biomed Mater Res 55 2001 350 359
30. K. Bessho, D.L. Carnes, and R. Cavin BMP stimulation of bone response adjacent to titanium implants in vivo Clin Oral Implants Res 10 1999 212 218
31. R. Olivares-Navarrete, R.A. Gittens, and J.M. Schneider Osteoblasts exhibit a more differentiated phenotype and increased BMP production on titanium alloy substrates than on PEEK Spine J 12 2012 265 272
32. Z. Schwartz, E. Nasazky, and B.D. Boyan Surface microtopography regulates osteointegration: the role of implant surface microtopography in osteointegration Alpha Omegan 98 2005 9 19
33. R. Olivares-Navarrete, S.L. Hyzy, and R.A. Chaudhri Sex dependent regulation of osteoblast response to implant surface properties by systemic hormones Biol Sex Differ 1 2010 4
34. C.H. Lohmann, E.M. Tandy, and V.L. Sylvia Response of normal female human osteoblasts (NHOst) to 17beta-estradiol is modulated by implant surface morphology J Biomed Mater Res 62 2002 204 213
35. G.B. Schneider, H. Perinpanayagam, and M. Clegg Implant surface roughness affects osteoblast gene expression J Dent Res 82 2003 372 376
36. R.J. Dekker, C.A. van Blitterswijk, and I. Hofland Studying the effect of different macrostructures on in vitro cell behaviour and in vivo bone formation using a tissue engineering approach Novartis Found Symp 249 2003 148 167 discussion 67-69, 70-74, 239-241
37. J.Y. Martin, Z. Schwartz, and T.W. Hummert Effect of titanium surface roughness on proliferation, differentiation, and protein synthesis of human osteoblast-like cells (MG63) J Biomed Mater Res 29 1995 389 401
38. D.L. Cochran, P.V. Nummikoski, and F.L. Higginbottom Evaluation of an endosseous titanium implant with a sandblasted and acid-etched surface in the canine mandible: radiographic results Clin Oral Implants Res 7 1996 240 252
39. T.J. Heino, and T.A. Hentunen Differentiation of osteoblasts and osteocytes from mesenchymal stem cells Curr Stem Cell Res Ther 3 2008 131 145
40. H.M. Eilken, and R.H. Adams Dynamics of endothelial cell behavior in sprouting angiogenesis Curr Opin Cell Biol 22 2010 617 625
41. C.H. Chen, S.M. Poucher, J. Lu, and P.D. Henry Fibroblast growth factor 2: from laboratory evidence to clinical application Curr Vasc Pharmacol 2 2004 33 43
42. P. Saharinen, M. Bry, and K. Alitalo How do angiopoietins tie in with vascular endothelial growth factors? Curr Opin Hematol 17 2010 198 205
43. K.H. Tan, C.K. Chua, and K.F. Leong Fabrication and characterization of three-dimensional poly(ether- ether- ketone)/-hydroxyapatite biocomposite scaffolds using laser sintering Proc Inst Mech Eng H 219 2005 183 194
44. C.M. Han, E.J. Lee, and H.E. Kim The electron beam deposition of titanium on polyetheretherketone (PEEK) and the resulting enhanced biological properties Biomaterials 31 2010 3465 3470
45. H. Wang, M. Xu, and W. Zhang Mechanical and biological characteristics of diamond-like carbon coated poly aryl-ether-ether-ketone Biomaterials 31 2010 8181 8187
46. L.F. Bonewald, and S.L. Dallas Role of active and latent transforming growth factor beta in bone formation J Cell Biochem 55 1994 350 357
47. K. Janssens, P. ten Dijke, S. Janssens, and W. Van Hul Transforming growth factor-beta1 to the bone Endocrine Rev 26 2005 743 774
48. Y. Kobayashi, N. Udagawa, and N. Takahashi Action of RANKL and OPG for osteoclastogenesis Crit Rev Eukaryot Gene Expr 19 2009 61 72