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Volumn 2013, Issue , 2013, Pages

Microglial ion channels as potential targets for neuroprotection in Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 2 [4 (2,5 DIFLUOROBENZYLOXY)PHENOXY] 5 ETHOXYANILINE; 3 NITROTYROSINE; 7 NITROINDAZOLE; ALPHA SYNUCLEIN; ALPHA TOCOPHEROL; APOCYNIN; CALCIUM CHANNEL; CALPAIN; DEXTROMETHORPHAN; DIPHENYLIODONIUM SALT; GLYCERYL TRINITRATE; IBUPROFEN; INDUCIBLE NITRIC OXIDE SYNTHASE; ION CHANNEL; ISRADIPINE; MINOCYCLINE; NEUROMELANIN; NIFEDIPINE; NIMODIPINE; NITRIC OXIDE; PARAQUAT; POTASSIUM CHANNEL; PROTON CHANNEL HV1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIPARKINSON AGENT; ION; NEUROPROTECTIVE AGENT;

EID: 84889071254     PISSN: 20905904     EISSN: 16875443     Source Type: Journal    
DOI: 10.1155/2013/587418     Document Type: Article
Times cited : (25)

References (77)
  • 2
    • 0032748299 scopus 로고    scopus 로고
    • Free radicals, oxidative stress and the origin of Parkinson's disease
    • DOI 10.1016/S0022-510X(99)00191-4, PII S0022510X99001914
    • Bennett J. P., Free radicals, oxidative stress and the origin of Parkinson's disease. Journal of the Neurological Sciences 1999 170 2 75 76 2-s2.0-0032748299 10.1016/S0022-510X(99)00191-4 (Pubitemid 29528528)
    • (1999) Journal of the Neurological Sciences , vol.170 , Issue.2 , pp. 75-76
    • Bennett, J.P.1
  • 3
    • 0025220976 scopus 로고
    • Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
    • 2-s2.0-0025220976 10.1016/0306-4522(90)90229-W
    • Lawson L. J., Perry V. H., Dri P., Gordon S., Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 1990 39 1 151 170 2-s2.0-0025220976 10.1016/0306-4522(90)90229-W
    • (1990) Neuroscience , vol.39 , Issue.1 , pp. 151-170
    • Lawson, L.J.1    Perry, V.H.2    Dri, P.3    Gordon, S.4
  • 5
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • Jenner P., Olanow C. W., Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 1996 47 6, supplement 3 S161 S170 2-s2.0-0029751104 (Pubitemid 26422582)
    • (1996) Neurology , vol.47 , Issue.6 SUPPL. 3
    • Jenner, P.1    Olanow, C.W.2
  • 6
    • 0023789193 scopus 로고
    • Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
    • 2-s2.0-0023789193
    • McGeer P. L., Itagaki S., Boyes B. E., McGeer E. G., Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988 38 8 1285 1291 2-s2.0-0023789193
    • (1988) Neurology , vol.38 , Issue.8 , pp. 1285-1291
    • McGeer, P.L.1    Itagaki, S.2    Boyes, B.E.3    McGeer, E.G.4
  • 7
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
    • DOI 10.1002/1531-8249(199910)46:4<598::AID-ANA7>3.0.CO;2-F
    • Langston J. W., Forno L. S., Tetrud J., Reeves A. G., Kaplan J. A., Karluk D., Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine exposure. Annals of Neurology 1999 46 4 598 605 (Pubitemid 29466438)
    • (1999) Annals of Neurology , vol.46 , Issue.4 , pp. 598-605
    • Langston, J.W.1    Forno, L.S.2    Tetrud, J.3    Reeves, A.G.4    Kaplan, J.A.5    Karluk, D.6
  • 8
    • 0037402801 scopus 로고    scopus 로고
    • Selective microglial activation in the rat rotenone model of Parkinson's disease
    • DOI 10.1016/S0304-3940(03)00172-1
    • Sherer T. B., Betarbet R., Kim J.-H., Greenamyre J. T., Selective microglial activation in the rat rotenone model of Parkinson's disease. Neuroscience Letters 2003 341 2 87 90 2-s2.0-0037402801 10.1016/S0304-3940(03) 00172-1 (Pubitemid 36398476)
    • (2003) Neuroscience Letters , vol.341 , Issue.2 , pp. 87-90
    • Sherer, T.B.1    Betarbet, R.2    Kim, J.-H.3    Greenamyre, J.T.4
  • 9
    • 34548360527 scopus 로고    scopus 로고
    • Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1
    • DOI 10.1124/mol.107.038158
    • Hamill C. E., Caudle W. M., Richardson J. R., Yuan H., Pennell K. D., Greene J. G., Miller G. W., Traynelis S. F., Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1. Molecular Pharmacology 2007 72 3 653 664 2-s2.0-34548360527 10.1124/mol.107.038158 (Pubitemid 47347300)
    • (2007) Molecular Pharmacology , vol.72 , Issue.3 , pp. 653-664
    • Hamill, C.E.1    Caudle, W.M.2    Richardson, J.R.3    Yuan, H.4    Pennell, K.D.5    Greene, J.G.6    Miller, G.W.7    Traynelis, S.F.8
  • 10
    • 33846308531 scopus 로고    scopus 로고
    • Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration
    • DOI 10.1016/j.nbd.2006.10.008, PII S0969996106002579
    • Purisai M. G., McCormack A. L., Cumine S., Li J., Isla M. Z., di Monte D. A., Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration. Neurobiology of Disease 2007 25 2 392 400 2-s2.0-33846308531 10.1016/j.nbd.2006.10.008 (Pubitemid 46124019)
    • (2007) Neurobiology of Disease , vol.25 , Issue.2 , pp. 392-400
    • Purisai, M.G.1    McCormack, A.L.2    Cumine, S.3    Li, J.4    Isla, M.Z.5    Di Monte, D.A.6
  • 11
    • 0242384667 scopus 로고    scopus 로고
    • Presence of Reactive Microglia in Monkey Substantia Nigra Years after 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Administration
    • DOI 10.1002/ana.10728
    • McGeer P. L., Schwab C., Parent A., Doudet D., Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine administration. Annals of Neurology 2003 54 5 599 604 2-s2.0-0242384667 10.1002/ana.10728 (Pubitemid 37346066)
    • (2003) Annals of Neurology , vol.54 , Issue.5 , pp. 599-604
    • McGeer, P.L.1    Schwab, C.2    Parent, A.3    Doudet, D.4
  • 13
    • 0028170916 scopus 로고
    • Clinical trials of neuroprotection in Parkinson's disease: Long-term selegiline and alpha-tocopherol treatment
    • 2-s2.0-0028170916
    • LeWitt P. A., Clinical trials of neuroprotection in Parkinson's disease: long-term selegiline and alpha-tocopherol treatment. Journal of Neural Transmission, Supplement 1994 43 171 181 2-s2.0-0028170916
    • (1994) Journal of Neural Transmission, Supplement , vol.43 , pp. 171-181
    • Lewitt, P.A.1
  • 16
    • 79952941281 scopus 로고    scopus 로고
    • Use of ibuprofen and risk of Parkinson disease
    • 2-s2.0-79952941281 10.1212/WNL.0b013e31820f2d79
    • Gao X., Chen H., Schwarzschild M. A., Ascherio A., Use of ibuprofen and risk of Parkinson disease. Neurology 2011 76 10 863 869 2-s2.0-79952941281 10.1212/WNL.0b013e31820f2d79
    • (2011) Neurology , vol.76 , Issue.10 , pp. 863-869
    • Gao, X.1    Chen, H.2    Schwarzschild, M.A.3    Ascherio, A.4
  • 17
    • 84856583697 scopus 로고    scopus 로고
    • The promise of neuroprotective agents in Parkinson's disease
    • Seidl S. E., Potashkin J. A., The promise of neuroprotective agents in Parkinson's disease. Frontiers in Neurology 2011 2 68
    • (2011) Frontiers in Neurology , vol.2 , pp. 68
    • Seidl, S.E.1    Potashkin, J.A.2
  • 18
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
    • Wu D. C., Jackson-Lewis V., Vila M., Tieu K., Teismann P., Vadseth C., Choi D.-K., Ischiropoulos H., Przedborski S., Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. Journal of Neuroscience 2002 22 5 1763 1771 2-s2.0-0036522967 (Pubitemid 35386294)
    • (2002) Journal of Neuroscience , vol.22 , Issue.5 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3    Tieu, K.4    Teismann, P.5    Vadseth, C.6    Choi, D.-K.7    Ischiropoulos, H.8    Przedborski, S.9
  • 20
    • 3042755065 scopus 로고    scopus 로고
    • Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease
    • DOI 10.1111/j.0953-816X.2004.03372.x
    • Diguet E., Fernagut P.-O., Wei X., Du Y., Rouland R., Gross C., Bezard E., Tison F., Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease. European Journal of Neuroscience 2004 19 12 3266 3276 2-s2.0-3042755065 10.1111/j.0953-816X.2004.03372.x (Pubitemid 38859544)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.12 , pp. 3266-3276
    • Diguet, E.1    Fernagut, P.-O.2    Wei, X.3    Du, Y.4    Rouland, R.5    Gross, C.6    Bezard, E.7    Tison, F.8
  • 21
    • 33645123006 scopus 로고    scopus 로고
    • Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: Role of tumor necrosis factor- α
    • 2-s2.0-33645123006 10.1111/j.1471-4159.2005.03566.x
    • Sriram K., Miller D. B., O'Callaghan J. P., Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor- α Journal of Neurochemistry 2006 96 3 706 718 2-s2.0-33645123006 10.1111/j.1471-4159.2005.03566.x
    • (2006) Journal of Neurochemistry , vol.96 , Issue.3 , pp. 706-718
    • Sriram, K.1    Miller, D.B.2    O'Callaghan, J.P.3
  • 24
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
    • DOI 10.1038/nrn2038, PII NRN2038
    • Block M. L., Zecca L., Hong J.-S., Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nature Reviews Neuroscience 2007 8 1 57 69 2-s2.0-33845768784 10.1038/nrn2038 (Pubitemid 46011999)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.1 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.-S.3
  • 25
    • 52449115580 scopus 로고    scopus 로고
    • The lipopolysaccharide Parkinson's disease animal model: Mechanistic studies and drug discovery
    • 2-s2.0-52449115580 10.1111/j.1472-8206.2008.00616.x
    • Dutta G., Zhang P., Liu B., The lipopolysaccharide Parkinson's disease animal model: mechanistic studies and drug discovery. Fundamental and Clinical Pharmacology 2008 22 5 453 464 2-s2.0-52449115580 10.1111/j.1472-8206.2008. 00616.x
    • (2008) Fundamental and Clinical Pharmacology , vol.22 , Issue.5 , pp. 453-464
    • Dutta, G.1    Zhang, P.2    Liu, B.3
  • 26
    • 77950251171 scopus 로고    scopus 로고
    • Reactive microgliosis: Extracellular-calpain and microglia-mediated dopaminergic neurotoxicity
    • 2-s2.0-77950251171 10.1093/brain/awp333
    • Levesque S., Wilson B., Gregoria V., Thorpe L. B., Dallas S., Polikov V. S., Hong J.-S., Block M. L., Reactive microgliosis: extracellular-calpain and microglia-mediated dopaminergic neurotoxicity. Brain 2010 133 3 808 821 2-s2.0-77950251171 10.1093/brain/awp333
    • (2010) Brain , vol.133 , Issue.3 , pp. 808-821
    • Levesque, S.1    Wilson, B.2    Gregoria, V.3    Thorpe, L.B.4    Dallas, S.5    Polikov, V.S.6    Hong, J.-S.7    Block, M.L.8
  • 27
    • 0037366093 scopus 로고    scopus 로고
    • Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: Implications for Parkinson's disease
    • 2-s2.0-0037366093
    • Wilms H., Rosenstiel P., Sievers J., Deuschl G., Zecca L., Lucius R., Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease. The FASEB Journal 2003 17 3 500 502 2-s2.0-0037366093
    • (2003) The FASEB Journal , vol.17 , Issue.3 , pp. 500-502
    • Wilms, H.1    Rosenstiel, P.2    Sievers, J.3    Deuschl, G.4    Zecca, L.5    Lucius, R.6
  • 30
    • 62549133546 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: A target for neuroprotection?
    • 2-s2.0-62549133546 10.1016/S1474-4422(09)70062-6
    • Hirsch E. C., Hunot S., Neuroinflammation in Parkinson's disease: a target for neuroprotection? The Lancet Neurology 2009 8 4 382 397 2-s2.0-62549133546 10.1016/S1474-4422(09)70062-6
    • (2009) The Lancet Neurology , vol.8 , Issue.4 , pp. 382-397
    • Hirsch, E.C.1    Hunot, S.2
  • 31
    • 0036719568 scopus 로고    scopus 로고
    • Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: Implications for Parkinson's disease
    • 2-s2.0-0036719568
    • Sriram K., Matheson J. M., Benkovic S. A., Miller D. B., Luster M. I., O'Callaghan J. P., Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease. The FASEB Journal 2002 16 11 1474 1476 2-s2.0-0036719568
    • (2002) The FASEB Journal , vol.16 , Issue.11 , pp. 1474-1476
    • Sriram, K.1    Matheson, J.M.2    Benkovic, S.A.3    Miller, D.B.4    Luster, M.I.5    O'Callaghan, J.P.6
  • 32
    • 70349832717 scopus 로고    scopus 로고
    • Heterogeneity of microglia and TNF signaling as determinants for neuronal death or survival
    • 2-s2.0-70349832717 10.1016/j.neuro.2009.07.001
    • Kraft A. D., McPherson C. A., Harry G. J., Heterogeneity of microglia and TNF signaling as determinants for neuronal death or survival. NeuroToxicology 2009 30 5 785 793 2-s2.0-70349832717 10.1016/j.neuro.2009.07.001
    • (2009) NeuroToxicology , vol.30 , Issue.5 , pp. 785-793
    • Kraft, A.D.1    McPherson, C.A.2    Harry, G.J.3
  • 33
    • 0346463000 scopus 로고    scopus 로고
    • NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia
    • DOI 10.1074/jbc.M307657200
    • Qin L., Liu Y., Wang T., Wei S.-J., Block M. L., Wilson B., Liu B., Hong J.-S., NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. Journal of Biological Chemistry 2004 279 2 1415 1421 2-s2.0-0346463000 10.1074/jbc.M307657200 (Pubitemid 38082669)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.2 , pp. 1415-1421
    • Qin, L.1    Liu, Y.2    Wang, T.3    Wei, S.-J.4    Block, M.L.5    Wilson, B.6    Liu, B.7    Hong, J.-S.8
  • 34
    • 84864334644 scopus 로고    scopus 로고
    • Targeting microglia-mediated neurotoxicity: The potential of NOX2 inhibitors
    • 10.1007/s00018-012-1015-4
    • Surace M. J., Block M. L., Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors. Cellular and Molecular Life Sciences 2012 69 14 2409 2427 10.1007/s00018-012-1015-4
    • (2012) Cellular and Molecular Life Sciences , vol.69 , Issue.14 , pp. 2409-2427
    • Surace, M.J.1    Block, M.L.2
  • 35
    • 0034458228 scopus 로고    scopus 로고
    • The NADPH oxidase of endothelial cells
    • DOI 10.1080/15216540051080976
    • Babior B. M., The NADPH oxidase of endothelial cells. IUBMB Life 2000 50 4-5 267 269 2-s2.0-0034458228 10.1080/15216540051080976 (Pubitemid 32289084)
    • (2000) IUBMB Life , vol.50 , Issue.4-5 , pp. 267-269
    • Babior, B.M.1
  • 36
    • 0034617071 scopus 로고    scopus 로고
    • A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
    • Görlach A., Brandes R. P., Nguyen K., Amidi M., Dehghani F., Busse R., A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall. Circulation Research 2000 87 1 26 32 2-s2.0-0034617071 (Pubitemid 30456931)
    • (2000) Circulation Research , vol.87 , Issue.1 , pp. 26-32
    • Gorlach, A.1    Brandes, R.P.2    Nguyen, K.3    Amidi, M.4    Dehghani, F.5    Busse, R.6
  • 37
    • 0036954803 scopus 로고    scopus 로고
    • phox-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis
    • DOI 10.1161/01.RES.0000046227.65158.F8
    • Ushio-Fukai M., Tang Y., Fukai T., Dikalov S. I., Ma Y., Fujimoto M., Quinn M. T., Pagano P. J., Johnson C., Alexander R. W., Novel role of gp91phox-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. Circulation Research 2002 91 12 1160 1167 2-s2.0-0036954803 10.1161/01.RES.0000046227.65158.F8 (Pubitemid 36076365)
    • (2002) Circulation Research , vol.91 , Issue.12 , pp. 1160-1167
    • Ushio-Fukai, M.1    Tang, Y.2    Fukai, T.3    Dikalov, S.I.4    Ma, Y.5    Fujimoto, M.6    Quinn, M.T.7    Pagano, P.J.8    Johnson, C.9    Alexander, R.W.10
  • 38
    • 84855570853 scopus 로고    scopus 로고
    • NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration
    • 2-s2.0-84855570853 10.1186/1742-2094-9-5
    • Qin L., Crews F. T., NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration. Journal of Neuroinflammation 2012 9, article 5 2-s2.0-84855570853 10.1186/1742-2094-9-5
    • (2012) Journal of Neuroinflammation , vol.95
    • Qin, L.1    Crews, F.T.2
  • 39
    • 67651184281 scopus 로고    scopus 로고
    • NOX enzymes in the central nervous system: From signaling to disease
    • 2-s2.0-67651184281 10.1089/ars.2009.2578
    • Sorce S., Krause K.-H., NOX enzymes in the central nervous system: from signaling to disease. Antioxidants and Redox Signaling 2009 11 10 2481 2504 2-s2.0-67651184281 10.1089/ars.2009.2578
    • (2009) Antioxidants and Redox Signaling , vol.11 , Issue.10 , pp. 2481-2504
    • Sorce, S.1    Krause, K.-H.2
  • 42
    • 84861854211 scopus 로고    scopus 로고
    • NADPH oxidases: Novel therapeutic targets for neurodegenerative diseases
    • 2-s2.0-84859514311 10.1016/j.tips.2012.03.008
    • Gao H.-M., Zhou H., Hong J.-S., NADPH oxidases: novel therapeutic targets for neurodegenerative diseases. Trends in Pharmacological Sciences 2012 33 6 295 303 2-s2.0-84859514311 10.1016/j.tips.2012.03.008
    • (2012) Trends in Pharmacological Sciences , vol.33 , Issue.6 , pp. 295-303
    • Gao, H.-M.1    Zhou, H.2    Hong, J.-S.3
  • 43
    • 69449105146 scopus 로고    scopus 로고
    • Sodium channel activity modulates multiple functions in microglia
    • 2-s2.0-69449105146 10.1002/glia.20830
    • Black J. A., Liu S., Waxman S. G., Sodium channel activity modulates multiple functions in microglia. Glia 2009 57 10 1072 1081 2-s2.0-69449105146 10.1002/glia.20830
    • (2009) Glia , vol.57 , Issue.10 , pp. 1072-1081
    • Black, J.A.1    Liu, S.2    Waxman, S.G.3
  • 44
    • 0031817079 scopus 로고    scopus 로고
    • Ion channels in microglia (brain macrophages)
    • 2-s2.0-0031817079
    • Eder C., Ion channels in microglia (brain macrophages). American Journal of Physiology-Cell Physiology 1998 275 2, part 1 C327 C342 2-s2.0-0031817079
    • (1998) American Journal of Physiology - Cell Physiology , vol.275 , Issue.2 PART 1
    • Eder, C.1
  • 45
    • 25444505872 scopus 로고    scopus 로고
    • Regulation of microglial behavior by ion channel activity
    • DOI 10.1002/jnr.20476
    • Eder C., Regulation of microglial behavior by ion channel activity. Journal of Neuroscience Research 2005 81 3 314 321 2-s2.0-25444505872 10.1002/jnr.20476 (Pubitemid 41359285)
    • (2005) Journal of Neuroscience Research , vol.81 , Issue.3 , pp. 314-321
    • Eder, C.1
  • 46
    • 37649011460 scopus 로고    scopus 로고
    • Ion channel expression in resting and activated microglia of hippocampal slices from juvenile mice
    • 2-s2.0-37649011460 10.1016/j.brainres.2007.10.027
    • Schilling T., Eder C., Ion channel expression in resting and activated microglia of hippocampal slices from juvenile mice. Brain Research 2007 1186 1 21 28 2-s2.0-37649011460 10.1016/j.brainres.2007.10.027
    • (2007) Brain Research , vol.1186 , Issue.1 , pp. 21-28
    • Schilling, T.1    Eder, C.2
  • 47
    • 17844396885 scopus 로고    scopus 로고
    • Physiology of microglial cells
    • DOI 10.1016/j.brainresrev.2004.12.003, Glial-Neuron Crosstalk in Neuroinflamation, Neurodegeneration and Neuroprotection
    • Färber K., Kettenmann H., Physiology of microglial cells. Brain Research Reviews 2005 48 2 133 143 2-s2.0-17844396885 10.1016/j.brainresrev. 2004.12.003 (Pubitemid 40585744)
    • (2005) Brain Research Reviews , vol.48 , Issue.2 , pp. 133-143
    • Farber, K.1    Kettenmann, H.2
  • 48
    • 33750305578 scopus 로고    scopus 로고
    • Functional role of calcium signals for microglial function
    • DOI 10.1002/glia.20412
    • Färber K., Kettenmann H., Functional role of calcium signals for microglial function. Glia 2006 54 7 656 665 2-s2.0-33750305578 10.1002/glia.20412 (Pubitemid 44629629)
    • (2006) GLIA , vol.54 , Issue.7 , pp. 656-665
    • Farber, K.1    Kettenmann, H.2
  • 49
    • 0025043211 scopus 로고
    • Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages
    • DOI 10.1002/jnr.490260303
    • Kettenmann H., Hoppe D., Gottmann K., Banati R., Kreutzberg G., Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages. Journal of Neuroscience Research 1990 26 3 278 287 2-s2.0-0025043211 10.1002/jnr.490260303 (Pubitemid 20264020)
    • (1990) Journal of Neuroscience Research , vol.26 , Issue.3 , pp. 278-287
    • Kettenmann, H.1    Hoppe, D.2    Gottmann, K.3    Banati, R.4    Kreutzberg, G.5
  • 51
    • 23444436221 scopus 로고    scopus 로고
    • Microglia Kv1.3 channels contribute to their ability to kill neurons
    • DOI 10.1523/JNEUROSCI.1251-05.2005
    • Fordyce C. B., Jagasia R., Zhu X., Schlichter L. C., Microglia Kv1.3 channels contribute to their ability to kill neurons. Journal of Neuroscience 2005 25 31 7139 7149 2-s2.0-23444436221 10.1523/JNEUROSCI.1251-05.2005 (Pubitemid 41113930)
    • (2005) Journal of Neuroscience , vol.25 , Issue.31 , pp. 7139-7149
    • Fordyce, C.B.1    Jagasia, R.2    Zhu, X.3    Schlichter, L.C.4
  • 52
    • 79960776760 scopus 로고    scopus 로고
    • Ion channels on microglia: Therapeutic targets for neuroprotection
    • 2-s2.0-79960776760
    • Skaper S. D., Ion channels on microglia: therapeutic targets for neuroprotection. CNS & Neurological Disorders Drug Targets 2011 10 1 44 56 2-s2.0-79960776760
    • (2011) CNS & Neurological Disorders Drug Targets , vol.10 , Issue.1 , pp. 44-56
    • Skaper, S.D.1
  • 53
    • 33846122620 scopus 로고    scopus 로고
    • + channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration
    • DOI 10.1523/JNEUROSCI.3593-06.2007
    • + channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration. Journal of Neuroscience 2007 27 1 234 244 2-s2.0-33846122620 10.1523/JNEUROSCI.3593-06.2007 (Pubitemid 46089977)
    • (2007) Journal of Neuroscience , vol.27 , Issue.1 , pp. 234-244
    • Kaushal, V.1    Koeberle, P.D.2    Wang, Y.3    Schlichter, L.C.4
  • 54
    • 84870763790 scopus 로고    scopus 로고
    • Protective roles for potassium SK/KCa2 channels in microglia and neurons
    • 10.3389/fphar.2012.00196
    • Dolga A. M., Culmsee C., Protective roles for potassium SK/KCa2 channels in microglia and neurons. Frontiers in Pharmacology 2012 3 196 10.3389/fphar.2012.00196
    • (2012) Frontiers in Pharmacology , vol.3 , pp. 196
    • Dolga, A.M.1    Culmsee, C.2
  • 55
    • 84859922500 scopus 로고    scopus 로고
    • ATP-dependent potassium channel blockade strengthens microglial neuroprotection after hypoxia-ischemia in rats
    • 2-s2.0-84859922500 10.1016/j.expneurol.2012.02.010
    • Ortega F. J., Gimeno-Bayon J., Espinosa-Parrilla J. F., Carrasco J. L., Batlle M., Pugliese M., Mahy N., Rodríguez M. J., ATP-dependent potassium channel blockade strengthens microglial neuroprotection after hypoxia-ischemia in rats. Experimental Neurology 2012 235 1 282 296 2-s2.0-84859922500 10.1016/j.expneurol.2012.02.010
    • (2012) Experimental Neurology , vol.235 , Issue.1 , pp. 282-296
    • Ortega, F.J.1    Gimeno-Bayon, J.2    Espinosa-Parrilla, J.F.3    Carrasco, J.L.4    Batlle, M.5    Pugliese, M.6    Mahy, N.7    Rodríguez, M.J.8
  • 57
    • 0036847845 scopus 로고    scopus 로고
    • Calcium signaling in microglial cells
    • DOI 10.1002/glia.10152
    • Möller T., Calcium signaling in microglial cells. Glia 2002 40 2 184 194 2-s2.0-0036847845 10.1002/glia.10152 (Pubitemid 35337376)
    • (2002) GLIA , vol.40 , Issue.2 , pp. 184-194
    • Moller, T.1
  • 58
    • 84869409550 scopus 로고    scopus 로고
    • CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease
    • 10.1038/ncomms2149
    • Kang S., Cooper G., Dunne S. F., Dusel B., Luan C. H., Surmeier D. J., Silverman R. B., CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease. Nature Communications 2012 3 1146 10.1038/ncomms2149
    • (2012) Nature Communications , vol.3 , pp. 1146
    • Kang, S.1    Cooper, G.2    Dunne, S.F.3    Dusel, B.4    Luan, C.H.5    Surmeier, D.J.6    Silverman, R.B.7
  • 59
    • 79958204001 scopus 로고    scopus 로고
    • The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease
    • 2-s2.0-79958204001 10.1016/j.nbd.2011.04.007
    • Ilijic E., Guzman J. N., Surmeier D. J., The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease. Neurobiology of Disease 2011 43 2 364 371 2-s2.0-79958204001 10.1016/j.nbd.2011.04.007
    • (2011) Neurobiology of Disease , vol.43 , Issue.2 , pp. 364-371
    • Ilijic, E.1    Guzman, J.N.2    Surmeier, D.J.3
  • 60
    • 58749084091 scopus 로고    scopus 로고
    • Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation
    • 2-s2.0-58749084091 10.1016/j.neuropharm.2008.10.016
    • Li Y., Hu X., Liu Y., Bao Y., An L., Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation. Neuropharmacology 2009 56 3 580 589 2-s2.0-58749084091 10.1016/j.neuropharm.2008.10.016
    • (2009) Neuropharmacology , vol.56 , Issue.3 , pp. 580-589
    • Li, Y.1    Hu, X.2    Liu, Y.3    Bao, Y.4    An, L.5
  • 63
    • 84858158701 scopus 로고    scopus 로고
    • Sodium channels and microglial function
    • 2-s2.0-84858158701 10.1016/j.expneurol.2011.09.030
    • Black J. A., Waxman S. G., Sodium channels and microglial function. Experimental Neurology 2012 234 2 302 315 2-s2.0-84858158701 10.1016/j.expneurol.2011.09.030
    • (2012) Experimental Neurology , vol.234 , Issue.2 , pp. 302-315
    • Black, J.A.1    Waxman, S.G.2
  • 64
    • 84892596807 scopus 로고    scopus 로고
    • Coordinated role of voltage-gated sodium channels and the Na/H exchanger in sustaining microglial activation during inflammation
    • 10.1016/j.taap.2013.09.011
    • Hossain M. M., Sonsalla P. K., Richardson J. R., Coordinated role of voltage-gated sodium channels and the Na/H exchanger in sustaining microglial activation during inflammation. Toxicology and Applied Pharmacology 2013 10.1016/j.taap.2013.09.011
    • (2013) Toxicology and Applied Pharmacology
    • Hossain, M.M.1    Sonsalla, P.K.2    Richardson, J.R.3
  • 65
    • 13244258365 scopus 로고    scopus 로고
    • Sodium channels contribute to microglia/macrophage activation and function in EAE and MS
    • DOI 10.1002/glia.20112
    • Craner M. J., Damarjian T. G., Liu S., Hains B. C., Lo A. C., Black J. A., Newcombe J., Cuzner M. L., Waxman S. G., Sodium channels contribute to microglia/macrophage activation and function in EAE and MS. Glia 2005 49 2 220 229 2-s2.0-13244258365 10.1002/glia.20112 (Pubitemid 40188501)
    • (2005) GLIA , vol.49 , Issue.2 , pp. 220-229
    • Craner, M.J.1    Damarjian, T.G.2    Liu, S.3    Hains, B.C.4    Lo, A.C.5    Black, J.A.6    Newcombe, J.7    Cuzner, M.L.8    Waxman, S.G.9
  • 66
    • 34547773583 scopus 로고    scopus 로고
    • Exacerbation of experimental autoimmune encephalomyelitis after withdrawal of phenytoin and carbamazepine
    • DOI 10.1002/ana.21172
    • Black J. A., Liu S., Carrithers M., Carrithers L. M., Waxman S. G., Exacerbation of experimental autoimmune encephalomyelitis after withdrawal of phenytoin and carbamazepine. Annals of Neurology 2007 62 1 21 33 2-s2.0-34547773583 10.1002/ana.21172 (Pubitemid 47235277)
    • (2007) Annals of Neurology , vol.62 , Issue.1 , pp. 21-33
    • Black, J.A.1    Liu, S.2    Carrithers, M.3    Carrithers, L.M.4    Waxman, S.G.5
  • 69
    • 0028851256 scopus 로고
    • Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion
    • 2-s2.0-0028851256 10.1016/0008-6363(96)88579-8
    • Scholz W., Albus U., Counillon L., Gögelein H., Lang H.-J., Linz W., Weichert A., Schölkens B. A., Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion. Cardiovascular Research 1995 29 2 260 268 2-s2.0-0028851256 10.1016/0008-6363(96)88579-8
    • (1995) Cardiovascular Research , vol.29 , Issue.2 , pp. 260-268
    • Scholz, W.1    Albus, U.2    Counillon, L.3    Gögelein, H.4    Lang, H.-J.5    Linz, W.6    Weichert, A.7    Schölkens, B.A.8
  • 70
    • 30544436513 scopus 로고    scopus 로고
    • + exchanger isoform 1-null mice after In Vitro and In Vivo ischemia
    • DOI 10.1523/JNEUROSCI.3271-05.2005
    • + exchanger isoform 1-null mice after in vitro and in vivo ischemia. Journal of Neuroscience 2005 25 49 11256 11268 2-s2.0-30544436513 10.1523/JNEUROSCI.3271-05.2005 (Pubitemid 43083700)
    • (2005) Journal of Neuroscience , vol.25 , Issue.49 , pp. 11256-11268
    • Luo, J.1    Chen, H.2    Kintner, D.B.3    Shull, G.E.4    Sun, D.5
  • 71
    • 80052647286 scopus 로고    scopus 로고
    • Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains
    • 2-s2.0-80052647286 10.1111/j.1471-4159.2011.07403.x
    • Shi Y., Chanana V., Watters J. J., Ferrazzano P., Sun D., Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains. Journal of Neurochemistry 2011 119 1 124 135 2-s2.0-80052647286 10.1111/j.1471-4159.2011.07403.x
    • (2011) Journal of Neurochemistry , vol.119 , Issue.1 , pp. 124-135
    • Shi, Y.1    Chanana, V.2    Watters, J.J.3    Ferrazzano, P.4    Sun, D.5
  • 75
    • 33646358260 scopus 로고    scopus 로고
    • A voltage-gated proton-selective channel lacking the pore domain
    • 2-s2.0-33646358260 10.1038/nature04700
    • Ramsey I. S., Moran M. M., Chong J. A., Clapham D. E., A voltage-gated proton-selective channel lacking the pore domain. Nature 2006 440 7088 1213 1216 2-s2.0-33646358260 10.1038/nature04700
    • (2006) Nature , vol.440 , Issue.7088 , pp. 1213-1216
    • Ramsey, I.S.1    Moran, M.M.2    Chong, J.A.3    Clapham, D.E.4
  • 76
    • 66149104077 scopus 로고    scopus 로고
    • Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst
    • 2-s2.0-66149104077 10.1073/pnas.0902761106
    • Ramsey I. S., Ruchti E., Kaczmarek J. S., Clapham D. E., Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst. Proceedings of the National Academy of Sciences of the United States of America 2009 106 18 7642 7647 2-s2.0-66149104077 10.1073/pnas.0902761106
    • (2009) Proceedings of the National Academy of Sciences of the United States of America , vol.106 , Issue.18 , pp. 7642-7647
    • Ramsey, I.S.1    Ruchti, E.2    Kaczmarek, J.S.3    Clapham, D.E.4


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