Impact of aeration strategies on fed-batch cell culture kinetics in a single-use 24-well miniature bioreactor

Biochemical Engineering Journal

Volumn 82, Issue , 2014, Pages 105-116

  Betts, J P J ^a   Warr, S R C ^b   Finka, G B ^b   Uden, M ^b   Town, M ^a   Janda, J M ^a   Baganz, F ^a   Lye, G J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Antibody production; CHO cell culture; Engineering characterisation; Miniature shaken bioreactor

Indexed keywords

ANTIBODIES; BATCH CELL CULTURE; BIOCONVERSION;

ANTIBODY PRODUCTION; BIOPHARMACEUTICAL PRODUCTS; BIOPROCESS DEVELOPMENT; CHO CELL CULTURES; GAS-LIQUID INTERFACIAL AREAS; OXYGEN MASS TRANSFER; SHAKE-FLASK CULTURES; SHAKEN BIOREACTORS;

BIOREACTORS;

AERATION; ANIMAL CELL; ANTIBODY TITER; ARTICLE; CELL DENSITY; CELL KINETICS; CELL VIABILITY; CHO CELL; CULTURE MEDIUM; FED BATCH CULTURE; FED BATCH REACTOR; FEMALE; GAS; NONHUMAN; PH; PRIORITY JOURNAL; SPACE; SPARGING; TEMPERATURE;

EID: 84889067259     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2013.11.010     Document Type: Article

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