Development and analysis of a mathematical model for antibody-producing GS-NSO cells under normal and hyperosmotic culture conditions

Biotechnology Progress

Volumn 22, Issue 6, 2006, Pages 1560-1569

  Ho, Yingswan ^a   Varley, Julie ^a   Mantalaris, Athanasios ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; GROWTH KINETICS; MATHEMATICAL MODELS; MONOCLONAL ANTIBODIES;

GLOBAL SENSITIVITY ANALYSIS (GSA); HYPEROSMOTIC CULTURE; IMMUNOGLOBULIN; SINGLE-CELL MODEL (SCM);

CELLS;

MONOCLONAL ANTIBODY; PARAPROTEIN; PROTEOME; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; COMPUTER SIMULATION; CULTURE TECHNIQUE; GENETICS; MECHANOTRANSDUCTION; METABOLISM; METHODOLOGY; MOUSE; MULTIPLE MYELOMA; OSMOTIC PRESSURE; PHYSIOLOGY; PROTEIN ENGINEERING; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; COMPUTER SIMULATION; MECHANOTRANSDUCTION, CELLULAR; MICE; MODELS, BIOLOGICAL; MULTIPLE MYELOMA; MYELOMA PROTEINS; OSMOTIC PRESSURE; PROTEIN ENGINEERING; PROTEOME; RECOMBINANT PROTEINS;

EID: 33845483671     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp060032b     Document Type: Article

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