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Volumn 11, Issue 5, 2013, Pages 354-364

Qualitative and quantitative variables that affect the potency of Fc-mediated effector function in vitro and in vivo: Considerations for passive immunization using non-neutralizing antibodies

Author keywords

Antibody structure; Antibody dependent cell mediated cytotoxicity; Antigen structure; Fc mediated effector function

Indexed keywords

B LYMPHOCYTE ANTIGEN; FC RECEPTOR; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; PLACEBO;

EID: 84889056040     PISSN: 1570162X     EISSN: 18734251     Source Type: Journal    
DOI: 10.2174/1570162X113116660060     Document Type: Article
Times cited : (24)

References (115)
  • 1
    • 0023111153 scopus 로고
    • Sera from HTLV-III/LAV antibody-positive individuals mediate antibody-dependent cellular cytotoxicity against HTLV-III/LAV-infected T cells
    • Rook AH, Lane HC, Folks T, et al. Sera from HTLV-III/LAV antibody-positive individuals mediate antibody-dependent cellular cytotoxicity against HTLV-III/LAV-infected T cells. J Immunol 1987; 138: 1064-7.
    • (1987) J Immunol , vol.138 , pp. 1064-1067
    • Rook, A.H.1    Lane, H.C.2    Folks, T.3
  • 2
    • 0023626964 scopus 로고
    • Antibody-dependent cellular cytotoxicity-inducing antibodies against human immunodeficiency virus. Presence at different clinical stages
    • Ljunggren K, Bottiger B, Biberfeld G, et al. Antibody-dependent cellular cytotoxicity-inducing antibodies against human immunodeficiency virus. Presence at different clinical stages. J Immunol 1987; 139: 2263-7.
    • (1987) J Immunol , vol.139 , pp. 2263-2267
    • Ljunggren, K.1    Bottiger, B.2    Biberfeld, G.3
  • 3
    • 0024255806 scopus 로고
    • Biological significance of the antibody response to HIV antigens expressed on the cell surface
    • Goudsmit J, Ljunggren K, Smit L, Jondal M, Fenyo EM. Biological significance of the antibody response to HIV antigens expressed on the cell surface. Arch Virol 1988; 103: 189-206.
    • (1988) Arch Virol , vol.103 , pp. 189-206
    • Goudsmit, J.1    Ljunggren, K.2    Smit, L.3    Jondal, M.4    Fenyo, E.M.5
  • 4
    • 0025181668 scopus 로고
    • Antibodies mediating cellular cytotoxicity and neutralization correlate with a better clinical stage in children born to human immunodeficiency virus-infected mothers
    • Ljunggren K, Moschese V, Broliden PA, et al. Antibodies mediating cellular cytotoxicity and neutralization correlate with a better clinical stage in children born to human immunodeficiency virus-infected mothers. J Infect Dis 1990; 161: 198-202.
    • (1990) J Infect Dis , vol.161 , pp. 198-202
    • Ljunggren, K.1    Moschese, V.2    Broliden, P.A.3
  • 5
    • 0024788517 scopus 로고
    • Serum and effectorcell antibody-dependent cellular cytotoxicity (ADCC) activity remains high during human immunodeficiency virus (HIV) disease progression
    • Ojo-Amaize E, Nishanian PG, Heitjan DF, et al. Serum and effectorcell antibody-dependent cellular cytotoxicity (ADCC) activity remains high during human immunodeficiency virus (HIV) disease progression. J Clin Immunol 1989; 9: 454-61.
    • (1989) J Clin Immunol , vol.9 , pp. 454-461
    • Ojo-Amaize, E.1    Nishanian, P.G.2    Heitjan, D.F.3
  • 6
    • 0024998989 scopus 로고
    • Possible beneficial effects of neutralizing antibodies and antibody-dependent, cell-mediated cytotoxicity in human immunodeficiency virus infection
    • Sawyer LA, Katzenstein DA, Hendry RM, et al. Possible beneficial effects of neutralizing antibodies and antibody-dependent, cell-mediated cytotoxicity in human immunodeficiency virus infection. AIDS Res Hum Retroviruses 1990; 6: 341-56.
    • (1990) AIDS Res Hum Retroviruses , vol.6 , pp. 341-356
    • Sawyer, L.A.1    Katzenstein, D.A.2    Hendry, R.M.3
  • 7
    • 0030240623 scopus 로고    scopus 로고
    • HIV-1 gp120-specific antibodydependent cell-mediated cytotoxicity correlates with rate of disease progression
    • Baum LL, Cassutt KJ, Knigge K, et al. HIV-1 gp120-specific antibodydependent cell-mediated cytotoxicity correlates with rate of disease progression. J Immunol 1996; 157: 2168-73.
    • (1996) J Immunol , vol.157 , pp. 2168-2173
    • Baum, L.L.1    Cassutt, K.J.2    Knigge, K.3
  • 8
    • 0025369235 scopus 로고
    • Failure of ADCC to predict HIV-associated disease progression or outcome in a haemophiliac cohort
    • Dalgleish A, Sinclair A, Steel M, et al. Failure of ADCC to predict HIV-associated disease progression or outcome in a haemophiliac cohort. Clin Exp Immunol 1990; 81: 5-10.
    • (1990) Clin Exp Immunol , vol.81 , pp. 5-10
    • Dalgleish, A.1    Sinclair, A.2    Steel, M.3
  • 9
    • 0028361845 scopus 로고
    • Association between anti-human immunodeficiency virus type 1 (HIV-1) antibodydependent cellular cytotoxicity antibody titers at birth and vertical transmission of HIV-1
    • Jenkins M, Landers D, Williams-Herman D, et al. Association between anti-human immunodeficiency virus type 1 (HIV-1) antibodydependent cellular cytotoxicity antibody titers at birth and vertical transmission of HIV-1. J Infect Dis 1994; 170: 308-12.
    • (1994) J Infect Dis , vol.170 , pp. 308-312
    • Jenkins, M.1    Landers, D.2    Williams-Herman, D.3
  • 10
    • 0027286286 scopus 로고
    • Antibody-dependent cellular cytotoxicity and neutralizing activity in sera of HIV-1-infected mothers and their children
    • Broliden K, Sievers E, Tovo PA, et al. Antibody-dependent cellular cytotoxicity and neutralizing activity in sera of HIV-1-infected mothers and their children. Clin Exp Immunol 1993; 93: 56-64.
    • (1993) Clin Exp Immunol , vol.93 , pp. 56-64
    • Broliden, K.1    Sievers, E.2    Tovo, P.A.3
  • 11
    • 0028180307 scopus 로고
    • Evidence for a defect of antibody-dependent cellular cytotoxic (ADCC) effector function and anti-HIV gp120/41-specific ADCC-mediating antibody titres in HIVinfected individuals
    • Ahmad A, Morisset R, Thomas R, Menezes J. Evidence for a defect of antibody-dependent cellular cytotoxic (ADCC) effector function and anti-HIV gp120/41-specific ADCC-mediating antibody titres in HIVinfected individuals. J Acquir Immune Defic Syndr 1994; 7: 428-37.
    • (1994) J Acquir Immune Defic Syndr , vol.7 , pp. 428-437
    • Ahmad, A.1    Morisset, R.2    Thomas, R.3    Menezes, J.4
  • 12
    • 0033378499 scopus 로고    scopus 로고
    • Maternal humoral factors associated with perinatal human immunodeficiency virus type-1 transmission in a cohort from Kigali, Rwanda, 1988-1994
    • Tranchat C, Van de Perre P, Simonon-Sorel A, et al. Maternal humoral factors associated with perinatal human immunodeficiency virus type-1 transmission in a cohort from Kigali, Rwanda, 1988-1994. J Infect 1999; 39: 213-20.
    • (1999) J Infect , vol.39 , pp. 213-220
    • Tranchat, C.1    Van de Perre, P.2    Simonon-Sorel, A.3
  • 13
    • 0034915448 scopus 로고    scopus 로고
    • Relationship between antibodydependent cellular cytotoxicity, plasma HIV type 1 RNA, and CD4+ lymphocyte count
    • Forthal DN, Landucci G, Keenan B. Relationship between antibodydependent cellular cytotoxicity, plasma HIV type 1 RNA, and CD4+ lymphocyte count. AIDS Res Hum Retroviruses 2001; 17: 553-61.
    • (2001) AIDS Res Hum Retroviruses , vol.17 , pp. 553-561
    • Forthal, D.N.1    Landucci, G.2    Keenan, B.3
  • 14
    • 0035037372 scopus 로고    scopus 로고
    • Evidence for a correlation between antibody-dependent cellular cytotoxicity-mediating anti-HIV-1 antibodies and prognostic predictors of HIV infection
    • Ahmad R, Sindhu ST, Toma E, et al. Evidence for a correlation between antibody-dependent cellular cytotoxicity-mediating anti-HIV-1 antibodies and prognostic predictors of HIV infection. J Clin Immunol 2001; 21: 227-33.
    • (2001) J Clin Immunol , vol.21 , pp. 227-233
    • Ahmad, R.1    Sindhu, S.T.2    Toma, E.3
  • 15
    • 9444249960 scopus 로고    scopus 로고
    • Women with cervicovaginal antibodydependent cell-mediated cytotoxicity have lower genital HIV-1 RNA loads
    • Nag P, Kim J, Sapiega V, et al. Women with cervicovaginal antibodydependent cell-mediated cytotoxicity have lower genital HIV-1 RNA loads. J Infect Dis 2004; 190: 1970-8.
    • (2004) J Infect Dis , vol.190 , pp. 1970-1978
    • Nag, P.1    Kim, J.2    Sapiega, V.3
  • 16
    • 79956335022 scopus 로고    scopus 로고
    • Immune escape from HIVspecific antibody-dependent cellular cytotoxicity (ADCC) pressure
    • Chung AW, Isitman G, Navis M, et al. Immune escape from HIVspecific antibody-dependent cellular cytotoxicity (ADCC) pressure. Proc Natl Acad Sci USA 2011; 108: 7505-10.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 7505-7510
    • Chung, A.W.1    Isitman, G.2    Navis, M.3
  • 17
    • 80052965433 scopus 로고    scopus 로고
    • Activation of NK cells by ADCC antibodies and HIV disease progression
    • Chung AW, Navis M, Isitman G, et al. Activation of NK cells by ADCC antibodies and HIV disease progression. J Acquir Immune Defic Syndr 2011; 58: 127-31.
    • (2011) J Acquir Immune Defic Syndr , vol.58 , pp. 127-131
    • Chung, A.W.1    Navis, M.2    Isitman, G.3
  • 18
    • 79957766689 scopus 로고    scopus 로고
    • Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals
    • Dugast AS, Tonelli A, Berger CT, et al. Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals. Virology 2011; 415: 160-7.
    • (2011) Virology , vol.415 , pp. 160-167
    • Dugast, A.S.1    Tonelli, A.2    Berger, C.T.3
  • 19
    • 69249213610 scopus 로고    scopus 로고
    • Matrix metalloprotease inhibitors restore impaired NK cell-mediated antibody-dependent cellular cytotoxicity in human immunodeficiency virus type 1 infection
    • Liu Q, Sun Y, Rihn S, et al. Matrix metalloprotease inhibitors restore impaired NK cell-mediated antibody-dependent cellular cytotoxicity in human immunodeficiency virus type 1 infection. J Virol 2009; 83: 8705-12.
    • (2009) J Virol , vol.83 , pp. 8705-8712
    • Liu, Q.1    Sun, Y.2    Rihn, S.3
  • 20
    • 84870439045 scopus 로고    scopus 로고
    • Impaired natural killer cell-induced antibodydependent cell-mediated cytotoxicity is associated with human immunodeficiency virus-1 disease progression
    • Jia M, Li D, He X, et al. Impaired natural killer cell-induced antibodydependent cell-mediated cytotoxicity is associated with human immunodeficiency virus-1 disease progression. Clin Exp Immunol 2013; 171: 107-16.
    • (2013) Clin Exp Immunol , vol.171 , pp. 107-116
    • Jia, M.1    Li, D.2    He, X.3
  • 21
    • 38849130057 scopus 로고    scopus 로고
    • FcgammaRIIa genotype predicts progression of HIV infection
    • Forthal DN, Landucci G, Bream J, et al. FcgammaRIIa genotype predicts progression of HIV infection. J Immunol 2007; 179: 7916-23.
    • (2007) J Immunol , vol.179 , pp. 7916-7923
    • Forthal, D.N.1    Landucci, G.2    Bream, J.3
  • 22
    • 0036435095 scopus 로고    scopus 로고
    • Sustained antibodydependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS
    • Banks ND, Kinsey N, Clements J, Hildreth JE. Sustained antibodydependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS. AIDS Res Hum Retroviruses 2002; 18: 1197-205.
    • (2002) AIDS Res Hum Retroviruses , vol.18 , pp. 1197-1205
    • Banks, N.D.1    Kinsey, N.2    Clements, J.3    Hildreth, J.E.4
  • 23
    • 0034958413 scopus 로고    scopus 로고
    • Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cells
    • Forthal DN, Landucci G, Daar ES. Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cells. J Virol 2001; 75: 6953-61.
    • (2001) J Virol , vol.75 , pp. 6953-6961
    • Forthal, D.N.1    Landucci, G.2    Daar, E.S.3
  • 24
    • 79960423934 scopus 로고    scopus 로고
    • Antibody-Dependent Cell-Mediated Cytotoxicity in Simian Immunodeficiency Virus-Infected Rhesus Monkeys
    • Sun Y, Asmal M, Lane S, et al. Antibody-Dependent Cell-Mediated Cytotoxicity in Simian Immunodeficiency Virus-Infected Rhesus Monkeys. J Virol 2011; 85(14): 6906-12.
    • (2011) J Virol , vol.85 , Issue.14 , pp. 6906-6912
    • Sun, Y.1    Asmal, M.2    Lane, S.3
  • 25
    • 79956107362 scopus 로고    scopus 로고
    • Antibody-Dependent Cell-Mediated Viral Inhibition Emerges after Simian Immunodeficiency Virus SIVmac251 Infection of Rhesus Monkeys Coincident with gp140-Binding Antibodies and Is Effective against Neutralization-Resistant Viruses
    • Asmal M, Sun Y, Lane S, et al. Antibody-Dependent Cell-Mediated Viral Inhibition Emerges after Simian Immunodeficiency Virus SIVmac251 Infection of Rhesus Monkeys Coincident with gp140-Binding Antibodies and Is Effective against Neutralization-Resistant Viruses. J Virol 2011; 85: 5465-75.
    • (2011) J Virol , vol.85 , pp. 5465-5475
    • Asmal, M.1    Sun, Y.2    Lane, S.3
  • 26
    • 84873704484 scopus 로고    scopus 로고
    • Compromised NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity in Chronic SIV/SHIV Infection
    • He X, Li D, Luo Z, et al. Compromised NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity in Chronic SIV/SHIV Infection. PloS One 2013; 8: e56309.
    • (2013) PloS One , vol.8
    • He, X.1    Li, D.2    Luo, Z.3
  • 27
    • 13544277161 scopus 로고    scopus 로고
    • Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251
    • Gomez-Roman VR, Patterson LJ, Venzon D, et al. Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251. J Immunol 2005; 174: 2185-9.
    • (2005) J Immunol , vol.174 , pp. 2185-2189
    • Gomez-Roman, V.R.1    Patterson, L.J.2    Venzon, D.3
  • 28
    • 0028058113 scopus 로고
    • Immune responses induced by prototype vaccines for AIDS in rhesus monkeys
    • Ohkawa S, Wilson LA, Larosa G, et al. Immune responses induced by prototype vaccines for AIDS in rhesus monkeys. AIDS Res Hum Retroviruses 1994; 10: 27-38.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 27-38
    • Ohkawa, S.1    Wilson, L.A.2    Larosa, G.3
  • 29
    • 0027991988 scopus 로고
    • Broadly reactive HIV-2 and SIVmac specific antibody-dependent cellular cytotoxicity in immunized and infected cynomolgus monkeys
    • von Gegerfelt A, Nilsson C, Putkonen P, Broliden K. Broadly reactive HIV-2 and SIVmac specific antibody-dependent cellular cytotoxicity in immunized and infected cynomolgus monkeys. Vaccine 1994; 12: 1203-8.
    • (1994) Vaccine , vol.12 , pp. 1203-1208
    • von Gegerfelt, A.1    Nilsson, C.2    Putkonen, P.3    Broliden, K.4
  • 30
    • 0028379713 scopus 로고
    • Efficacy of inactivated whole HIV-2 vaccines with various adjuvants in cynomolgus monkeys
    • Putkonen P, Nilsson C, Walther L, et al. Efficacy of inactivated whole HIV-2 vaccines with various adjuvants in cynomolgus monkeys. J Med Primatol 1994; 23: 89-94.
    • (1994) J Med Primatol , vol.23 , pp. 89-94
    • Putkonen, P.1    Nilsson, C.2    Walther, L.3
  • 31
    • 42649138896 scopus 로고    scopus 로고
    • Replicating adenovirus HIV/SIV recombinant priming alone or in combination with a gp140 protein boost results in significant control of viremia following a SHIV89. 6P challenge in Mamu-A*01 negative rhesus macaques
    • Patterson LJ, Beal J, Demberg T, et al. Replicating adenovirus HIV/SIV recombinant priming alone or in combination with a gp140 protein boost results in significant control of viremia following a SHIV89. 6P challenge in Mamu-A*01 negative rhesus macaques. Virology 2008; 374: 322-37.
    • (2008) Virology , vol.374 , pp. 322-337
    • Patterson, L.J.1    Beal, J.2    Demberg, T.3
  • 32
    • 65449179917 scopus 로고    scopus 로고
    • Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with tat/env compared with multigenic vaccines
    • Florese RH, Demberg T, Xiao P, et al. Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with tat/env compared with multigenic vaccines. J Immunol 2009; 182: 3718-27.
    • (2009) J Immunol , vol.182 , pp. 3718-3727
    • Florese, R.H.1    Demberg, T.2    Xiao, P.3
  • 33
    • 77953756732 scopus 로고    scopus 로고
    • Multiple vaccine-elicited nonneutralizing antienvelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following simian/human immunodeficiency virus SHIV89. 6P challenge in rhesus macaques
    • Xiao P, Zhao J, Patterson LJ, et al. Multiple vaccine-elicited nonneutralizing antienvelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following simian/human immunodeficiency virus SHIV89. 6P challenge in rhesus macaques. J Virol 2010; 84: 7161-73.
    • (2010) J Virol , vol.84 , pp. 7161-7173
    • Xiao, P.1    Zhao, J.2    Patterson, L.J.3
  • 34
    • 84860317371 scopus 로고    scopus 로고
    • Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated lowdose rectal SIV(mac251) challenge
    • Xiao P, Patterson LJ, Kuate S, et al. Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated lowdose rectal SIV(mac251) challenge. J Virol 2012; 86: 4644-57.
    • (2012) J Virol , vol.86 , pp. 4644-4657
    • Xiao, P.1    Patterson, L.J.2    Kuate, S.3
  • 35
    • 79954627394 scopus 로고    scopus 로고
    • Vaccine-elicited SIV and HIV envelope-specific IgA and IgG memory B cells in rhesus macaque peripheral blood correlate with functional antibody responses and reduced viremia
    • Brocca-Cofano E, McKinnon K, Demberg T, et al. Vaccine-elicited SIV and HIV envelope-specific IgA and IgG memory B cells in rhesus macaque peripheral blood correlate with functional antibody responses and reduced viremia. Vaccine 2011; 29: 3310-9.
    • (2011) Vaccine , vol.29 , pp. 3310-3319
    • Brocca-Cofano, E.1    McKinnon, K.2    Demberg, T.3
  • 36
    • 84866150457 scopus 로고    scopus 로고
    • ADCC Develops Over Time during Persistent Infection with Live-Attenuated SIV and Is Associated with Complete Protection against SIV(mac)251 Challenge
    • Alpert MD, Harvey JD, Lauer WA, et al. ADCC Develops Over Time during Persistent Infection with Live-Attenuated SIV and Is Associated with Complete Protection against SIV(mac)251 Challenge. PLoS Pathog 2012; 8: e1002890.
    • (2012) PLoS Pathog , vol.8
    • Alpert, M.D.1    Harvey, J.D.2    Lauer, W.A.3
  • 37
    • 34248168722 scopus 로고    scopus 로고
    • Recombinant gp120 Vaccine-Induced Antibodies Inhibit Clinical Strains of HIV-1 in the Presence of Fc Receptor-Bearing Effector Cells and Correlate Inversely with HIV Infection Rate
    • Forthal DN, Gilbert PB, Landucci G, Phan T. Recombinant gp120 Vaccine-Induced Antibodies Inhibit Clinical Strains of HIV-1 in the Presence of Fc Receptor-Bearing Effector Cells and Correlate Inversely with HIV Infection Rate. J Immunol 2007; 178: 6596-603.
    • (2007) J Immunol , vol.178 , pp. 6596-6603
    • Forthal, D.N.1    Gilbert, P.B.2    Landucci, G.3    Phan, T.4
  • 38
    • 84859393693 scopus 로고    scopus 로고
    • Immune-correlates analysis of an HIV-1 vaccine efficacy trial
    • Haynes BF, Gilbert PB, McElrath MJ, et al. Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med 2012; 366: 1275-86.
    • (2012) N Engl J Med , vol.366 , pp. 1275-1286
    • Haynes, B.F.1    Gilbert, P.B.2    McElrath, M.J.3
  • 39
    • 13944254982 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
    • Flynn NM, Forthal DN, Harro CD, et al. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J Infect Dis 2005; 191: 654-65.
    • (2005) J Infect Dis , vol.191 , pp. 654-665
    • Flynn, N.M.1    Forthal, D.N.2    Harro, C.D.3
  • 40
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
    • Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med 2009; 361: 2209-20.
    • (2009) N Engl J Med , vol.361 , pp. 2209-2220
    • Rerks-Ngarm, S.1    Pitisuttithum, P.2    Nitayaphan, S.3
  • 41
    • 84862764447 scopus 로고    scopus 로고
    • Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVACHIV (vCP1521) and AIDSVAX B/E: A post-hoc analysis of the Thai phase 3 efficacy trial RV 144
    • Robb ML, Rerks-Ngarm S, Nitayaphan S, et al. Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVACHIV (vCP1521) and AIDSVAX B/E: a post-hoc analysis of the Thai phase 3 efficacy trial RV 144. Lancet Infect Dis 2012; 12: 531-7.
    • (2012) Lancet Infect Dis , vol.12 , pp. 531-537
    • Robb, M.L.1    Rerks-Ngarm, S.2    Nitayaphan, S.3
  • 42
    • 79960342938 scopus 로고    scopus 로고
    • An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum
    • Ferrari G, Pollara J, Kozink D, et al. An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum. J Virol 2011; 85: 7029-36.
    • (2011) J Virol , vol.85 , pp. 7029-7036
    • Ferrari, G.1    Pollara, J.2    Kozink, D.3
  • 43
    • 84871960572 scopus 로고    scopus 로고
    • Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding
    • Guan Y, Pazgier M, Sajadi MM, et al. Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding. Proc Natl Acad Sci USA 2013; 110: E69-78.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 69-78
    • Guan, Y.1    Pazgier, M.2    Sajadi, M.M.3
  • 44
    • 84867902474 scopus 로고    scopus 로고
    • ADCC-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family
    • Bonsignori M, Pollara J, Moody MA, et al. ADCC-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family. J Virol 2012; 86(21): 11521-32.
    • (2012) J Virol , vol.86 , Issue.21 , pp. 11521-11532
    • Bonsignori, M.1    Pollara, J.2    Moody, M.A.3
  • 45
    • 84878430727 scopus 로고    scopus 로고
    • Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG
    • Tomaras GD, Ferrari G, Shen X, et al. Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG. Proc Natl Acad Sci USA 2013; 110(22): 9019-24.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.22 , pp. 9019-9024
    • Tomaras, G.D.1    Ferrari, G.2    Shen, X.3
  • 46
    • 33748482187 scopus 로고    scopus 로고
    • Evaluation of passively transferred, nonneutralizing antibody-dependent cellular cytotoxicitymediating IgG in protection of neonatal rhesus macaques against oral SIVmac251 challenge
    • Florese RH, Van Rompay KK, Aldrich K, et al. Evaluation of passively transferred, nonneutralizing antibody-dependent cellular cytotoxicitymediating IgG in protection of neonatal rhesus macaques against oral SIVmac251 challenge. J Immunol 2006; 177: 4028-36.
    • (2006) J Immunol , vol.177 , pp. 4028-4036
    • Florese, R.H.1    Van Rompay, K.K.2    Aldrich, K.3
  • 47
    • 34548496893 scopus 로고    scopus 로고
    • Fc receptor but not complement binding is important in antibody protection against HIV
    • Hessell AJ, Hangartner L, Hunter M, et al. Fc receptor but not complement binding is important in antibody protection against HIV. Nature 2007; 449: 101-4.
    • (2007) Nature , vol.449 , pp. 101-104
    • Hessell, A.J.1    Hangartner, L.2    Hunter, M.3
  • 48
    • 68349160853 scopus 로고    scopus 로고
    • Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
    • Hessell AJ, Poignard P, Hunter M, et al. Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques. Nat Med 2009; 15(8): 951-4.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 951-954
    • Hessell, A.J.1    Poignard, P.2    Hunter, M.3
  • 49
    • 84863579036 scopus 로고    scopus 로고
    • A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcgammaRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques
    • Moldt B, Shibata-Koyama M, Rakasz EG, et al. A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcgammaRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques. J Virol 2012; 86: 6189-96.
    • (2012) J Virol , vol.86 , pp. 6189-6196
    • Moldt, B.1    Shibata-Koyama, M.2    Rakasz, E.G.3
  • 50
    • 0026332977 scopus 로고
    • Prevention of HIV infection by passive immunization with HIV immunoglobulin
    • Prince AM, Reesink H, Pascual D, et al. Prevention of HIV infection by passive immunization with HIV immunoglobulin. AIDS Res Hum Retroviruses 1991; 7: 971-3.
    • (1991) AIDS Res Hum Retroviruses , vol.7 , pp. 971-973
    • Prince, A.M.1    Reesink, H.2    Pascual, D.3
  • 51
    • 0025900886 scopus 로고
    • Prevention of HIV-2 and SIVsm infection by passive immunization in cynomolgus monkeys
    • Putkonen P, Thorstensson R, Ghavamzadeh L, et al. Prevention of HIV-2 and SIVsm infection by passive immunization in cynomolgus monkeys. Nature 1991; 352: 436-8.
    • (1991) Nature , vol.352 , pp. 436-438
    • Putkonen, P.1    Thorstensson, R.2    Ghavamzadeh, L.3
  • 52
    • 0027537122 scopus 로고
    • hu-PBL-SCID mice can be protected from HIV-1 infection by passive transfer of monoclonal antibody to the principal neutralizing determinant of envelope gp120
    • Safrit JT, Fung MS, Andrews CA, et al. hu-PBL-SCID mice can be protected from HIV-1 infection by passive transfer of monoclonal antibody to the principal neutralizing determinant of envelope gp120. AIDS 1993; 7: 15-21.
    • (1993) AIDS , vol.7 , pp. 15-21
    • Safrit, J.T.1    Fung, M.S.2    Andrews, C.A.3
  • 53
    • 0028950509 scopus 로고
    • Pre-and postexposure protection against human immunodeficiency virus type 1 infection mediated by a monoclonal antibody
    • Gauduin MC, Safrit JT, Weir R, Fung MS, Koup RA. Pre-and postexposure protection against human immunodeficiency virus type 1 infection mediated by a monoclonal antibody. J Infect Dis 1995; 171: 1203-9.
    • (1995) J Infect Dis , vol.171 , pp. 1203-1209
    • Gauduin, M.C.1    Safrit, J.T.2    Weir, R.3    Fung, M.S.4    Koup, R.A.5
  • 54
    • 0029058337 scopus 로고
    • Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site
    • Parren PW, Ditzel HJ, Gulizia RJ, et al. Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site. AIDS 1995; 9: F1-6.
    • (1995) AIDS , vol.9 , pp. 1-6
    • Parren, P.W.1    Ditzel, H.J.2    Gulizia, R.J.3
  • 55
    • 0031449456 scopus 로고    scopus 로고
    • Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1
    • Gauduin M-C, parren PWHI, Weir R, et al. Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1. Nat Med 1997; 3: 1389-93.
    • (1997) Nat Med , vol.3 , pp. 1389-1393
    • Gauduin, M.-C.1    Parren, P.W.H.I.2    Weir, R.3
  • 56
    • 0033951746 scopus 로고    scopus 로고
    • Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
    • Mascola JR, Stiegler G, VanCott TC, et al. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat Med 2000; 6: 207-10.
    • (2000) Nat Med , vol.6 , pp. 207-210
    • Mascola, J.R.1    Stiegler, G.2    VanCott, T.C.3
  • 57
    • 0034864776 scopus 로고    scopus 로고
    • Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
    • Parren PW, Marx PA, Hessell AJ, et al. Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. J Virol 2001; 75: 8340-7.
    • (2001) J Virol , vol.75 , pp. 8340-8347
    • Parren, P.W.1    Marx, P.A.2    Hessell, A.J.3
  • 58
    • 17944380337 scopus 로고    scopus 로고
    • Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies
    • Ruprecht RM, Hofmann-Lehmann R, Smith-Franklin BA, et al. Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies. Transfus Clin Biol 2001; 8: 350-8.
    • (2001) Transfus Clin Biol , vol.8 , pp. 350-358
    • Ruprecht, R.M.1    Hofmann-Lehmann, R.2    Smith-Franklin, B.A.3
  • 59
    • 2942534479 scopus 로고    scopus 로고
    • Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies
    • Ferrantelli F, Rasmussen RA, Buckley KA, et al. Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies. J Infect Dis 2004; 189: 2167-73.
    • (2004) J Infect Dis , vol.189 , pp. 2167-2173
    • Ferrantelli, F.1    Rasmussen, R.A.2    Buckley, K.A.3
  • 60
    • 79960585840 scopus 로고    scopus 로고
    • Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody
    • Burton DR, Hessell AJ, Keele BF, et al. Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody. Proc Natl Acad Sci USA 2011; 108(27): 11181-6.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.27 , pp. 11181-11186
    • Burton, D.R.1    Hessell, A.J.2    Keele, B.F.3
  • 61
    • 84869232528 scopus 로고    scopus 로고
    • Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
    • Moldt B, Rakasz EG, Schultz N, et al. Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo. Proc Natl Acad Sci USA 2012; 109: 18921-5.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 18921-18925
    • Moldt, B.1    Rakasz, E.G.2    Schultz, N.3
  • 62
    • 84884654418 scopus 로고    scopus 로고
    • Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques
    • Moog C, Dereuddre-Bosquet N, Teillaud JL, et al. Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques. Mucosal Immunol 2013.
    • (2013) Mucosal Immunol
    • Moog, C.1    Dereuddre-Bosquet, N.2    Teillaud, J.L.3
  • 63
    • 0027985431 scopus 로고
    • Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
    • Burton DR, Pyati J, Koduri R, et al. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 1994; 266: 1024-27.
    • (1994) Science , vol.266 , pp. 1024-1027
    • Burton, D.R.1    Pyati, J.2    Koduri, R.3
  • 64
    • 0037213247 scopus 로고    scopus 로고
    • Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120
    • Pantophlet R, Ollmann Saphire E, Poignard P, et al. Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120. J Virol 2003; 77: 642-58.
    • (2003) J Virol , vol.77 , pp. 642-658
    • Pantophlet, R.1    Ollmann Saphire, E.2    Poignard, P.3
  • 65
    • 0032552454 scopus 로고    scopus 로고
    • Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41
    • Cavacini LA, Emes CL, Wisnewski AV, et al. Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41. AIDS Res Hum Retroviruses 1998; 14: 1271-80.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , pp. 1271-1280
    • Cavacini, L.A.1    Emes, C.L.2    Wisnewski, A.V.3
  • 66
    • 80055020243 scopus 로고    scopus 로고
    • A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcgamma receptors to define the role of effector functions in protection against HIV
    • Moldt B, Schultz N, Dunlop DC, et al. A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcgamma receptors to define the role of effector functions in protection against HIV. J Virol 2011; 85: 10572-81.
    • (2011) J Virol , vol.85 , pp. 10572-10581
    • Moldt, B.1    Schultz, N.2    Dunlop, D.C.3
  • 67
    • 2342627375 scopus 로고    scopus 로고
    • Effects of antibody on viral kinetics in simian/human immunodeficiency virus infection: Implications for vaccination
    • Zhang L, Ribeiro RM, Mascola JR, et al. Effects of antibody on viral kinetics in simian/human immunodeficiency virus infection: implications for vaccination. J Virol 2004; 78: 5520-2.
    • (2004) J Virol , vol.78 , pp. 5520-5522
    • Zhang, L.1    Ribeiro, R.M.2    Mascola, J.R.3
  • 68
    • 0031761965 scopus 로고    scopus 로고
    • Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: A candidate SIV vaccine
    • Arthur LO, Bess JW, Jr., Chertova EN, et al. Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: a candidate SIV vaccine. AIDS Res Hum Retroviruses 1998; 14 Suppl 3: S311-9.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , Issue.SUPPL. 3 , pp. 311-319
    • Arthur, L.O.1    Bess Jr., J.W.2    Chertova, E.N.3
  • 69
    • 0031694872 scopus 로고    scopus 로고
    • Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins
    • Rossio JL, Esser MT, Suryanarayana K, et al. Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins. J Virol 1998; 72: 7992-8001.
    • (1998) J Virol , vol.72 , pp. 7992-8001
    • Rossio, J.L.1    Esser, M.T.2    Suryanarayana, K.3
  • 70
    • 0033780046 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
    • O'Doherty U, Swiggard WJ, Malim MH. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding. J Virol 2000; 74: 10074-80.
    • (2000) J Virol , vol.74 , pp. 10074-10080
    • O'Doherty, U.1    Swiggard, W.J.2    Malim, M.H.3
  • 71
    • 0025861673 scopus 로고
    • Two immunodominant domains of gp41 bind antibodies which enhance human immunodeficiency virus type 1 infection in vitro
    • Robinson WE, Jr., Gorny MK, Xu JY, Mitchell WM, Zolla-Pazner S. Two immunodominant domains of gp41 bind antibodies which enhance human immunodeficiency virus type 1 infection in vitro. J Virol 1991; 65: 4169-76.
    • (1991) J Virol , vol.65 , pp. 4169-4176
    • Robinson Jr., W.E.1    Gorny, M.K.2    Xu, J.Y.3    Mitchell, W.M.4    Zolla-Pazner, S.5
  • 72
    • 0026055421 scopus 로고
    • Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies
    • Xu JY, Gorny MK, Palker T, Karwowska S, Zolla-Pazner S. Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies. J Virol 1991; 65: 4832-8.
    • (1991) J Virol , vol.65 , pp. 4832-4838
    • Xu, J.Y.1    Gorny, M.K.2    Palker, T.3    Karwowska, S.4    Zolla-Pazner, S.5
  • 73
    • 0028155283 scopus 로고
    • Electrofusion and EBVtransformation for PBL-immortalization: Generation of human monoclonal antibodies against HIV-1 proteins
    • Buchacher A, Predl R, Strutzenberger W, et al. Electrofusion and EBVtransformation for PBL-immortalization: generation of human monoclonal antibodies against HIV-1 proteins. AIDS Res Hum Retroviruses 1994; 10: 359-69.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 359-369
    • Buchacher, A.1    Predl, R.2    Strutzenberger, W.3
  • 74
    • 33744916994 scopus 로고    scopus 로고
    • Nonneutralizing antibodies are able to inhibit human immunodeficiency virus type 1 replication in macrophages and immature dendritic cells
    • Holl V, Peressin M, Decoville T, et al. Nonneutralizing antibodies are able to inhibit human immunodeficiency virus type 1 replication in macrophages and immature dendritic cells. J Virol 2006; 80: 6177-81.
    • (2006) J Virol , vol.80 , pp. 6177-6181
    • Holl, V.1    Peressin, M.2    Decoville, T.3
  • 75
    • 67249131966 scopus 로고    scopus 로고
    • Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
    • Hessell AJ, Rakasz EG, Poignard P, et al. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog 2009; 5: e1000433.
    • (2009) PLoS Pathog , vol.5
    • Hessell, A.J.1    Rakasz, E.G.2    Poignard, P.3
  • 76
    • 73949154006 scopus 로고    scopus 로고
    • Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L
    • Hessell AJ, Rakasz EG, Tehrani DM, et al. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L. J Virol 2010; 84: 1302-13.
    • (2010) J Virol , vol.84 , pp. 1302-1313
    • Hessell, A.J.1    Rakasz, E.G.2    Tehrani, D.M.3
  • 77
    • 84870701546 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies against HIV-1: Templates for a vaccine
    • van Gils MJ, Sanders RW. Broadly neutralizing antibodies against HIV-1: templates for a vaccine. Virology 2013; 435: 46-56.
    • (2013) Virology , vol.435 , pp. 46-56
    • van Gils, M.J.1    Sanders, R.W.2
  • 78
    • 84862245287 scopus 로고    scopus 로고
    • Translating basic mechanisms of IgG effector activity into next generation cancer therapies
    • Nimmerjahn F, Ravetch JV. Translating basic mechanisms of IgG effector activity into next generation cancer therapies. Cancer Immun 2012; 12: 13.
    • (2012) Cancer Immun , vol.12 , pp. 13
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 80
    • 1142298744 scopus 로고    scopus 로고
    • Human antibody-Fc receptor interactions illuminated by crystal structures. Nature reviews
    • Woof JM, Burton DR. Human antibody-Fc receptor interactions illuminated by crystal structures. Nature reviews. Immunology 2004; 4: 89-99.
    • (2004) Immunology , vol.4 , pp. 89-99
    • Woof, J.M.1    Burton, D.R.2
  • 81
    • 67650671880 scopus 로고    scopus 로고
    • Functional and clinical consequences of Fc receptor polymorphic and copy number variants
    • Bournazos S, Woof JM, Hart SP, Dransfield I. Functional and clinical consequences of Fc receptor polymorphic and copy number variants. Clin Exp Immunol 2009; 157: 244-54.
    • (2009) Clin Exp Immunol , vol.157 , pp. 244-254
    • Bournazos, S.1    Woof, J.M.2    Hart, S.P.3    Dransfield, I.4
  • 82
    • 77951610700 scopus 로고    scopus 로고
    • FcgammaRIIB in autoimmunity and infection: Evolutionary and therapeutic implications
    • Smith KG, Clatworthy MR. FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications. Nat Rev Immunol 2010; 10: 328-43.
    • (2010) Nat Rev Immunol , vol.10 , pp. 328-343
    • Smith, K.G.1    Clatworthy, M.R.2
  • 83
    • 0024586657 scopus 로고
    • GP120 specific cellular cytotoxicity in HIV-1 seropositive individuals. Evidence for circulating CD16+ effector cells armed in vivo with cytophilic antibody
    • Tyler DS, Nastala CL, Stanley SD, et al. GP120 specific cellular cytotoxicity in HIV-1 seropositive individuals. Evidence for circulating CD16+ effector cells armed in vivo with cytophilic antibody. J Immunol 1989; 142: 1177-82.
    • (1989) J Immunol , vol.142 , pp. 1177-1182
    • Tyler, D.S.1    Nastala, C.L.2    Stanley, S.D.3
  • 84
    • 0025223369 scopus 로고
    • Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies
    • Tyler DS, Stanley SD, Zolla-Pazner S, et al. Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies. J Immunol 1990; 145: 3276-82.
    • (1990) J Immunol , vol.145 , pp. 3276-3282
    • Tyler, D.S.1    Stanley, S.D.2    Zolla-Pazner, S.3
  • 85
    • 0026042547 scopus 로고
    • Antibody-dependent cellmediated cytotoxicity directed by a human monoclonal antibody reactive with gp120 of HIV-1
    • Koup RA, Robinson JE, Nguyen QV, et al. Antibody-dependent cellmediated cytotoxicity directed by a human monoclonal antibody reactive with gp120 of HIV-1. AIDS 1991; 5: 1309-14.
    • (1991) AIDS , vol.5 , pp. 1309-1314
    • Koup, R.A.1    Robinson, J.E.2    Nguyen, Q.V.3
  • 86
    • 0028177874 scopus 로고
    • Studies with monoclonal antibodies to the V3 region of HIV-1 gp120 reveal limitations to the utility of solid-phase peptide binding assays
    • Moore JP, Cao Y, Conley AJ, et al. Studies with monoclonal antibodies to the V3 region of HIV-1 gp120 reveal limitations to the utility of solid-phase peptide binding assays. J Acquir Immune Defic Syndr 1994; 7: 332-9.
    • (1994) J Acquir Immune Defic Syndr , vol.7 , pp. 332-339
    • Moore, J.P.1    Cao, Y.2    Conley, A.J.3
  • 87
    • 84858602145 scopus 로고    scopus 로고
    • Vaccine induced antibodies to the first variable loop of human immunodeficiency virus type 1 gp120, mediate antibody-dependent virus inhibition in macaques
    • Bialuk I, Whitney S, Andresen V, et al. Vaccine induced antibodies to the first variable loop of human immunodeficiency virus type 1 gp120, mediate antibody-dependent virus inhibition in macaques. Vaccine 2011; 30: 78-94.
    • (2011) Vaccine , vol.30 , pp. 78-94
    • Bialuk, I.1    Whitney, S.2    Andresen, V.3
  • 88
    • 75749133275 scopus 로고    scopus 로고
    • Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility
    • Pancera M, Majeed S, Ban YE, et al. Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. Proc Natl Acad Sci USA 2010; 107: 1166-71.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 1166-1171
    • Pancera, M.1    Majeed, S.2    Ban, Y.E.3
  • 89
    • 77953657737 scopus 로고    scopus 로고
    • Alanine scanning mutagenesis of HIV-1 gp41 heptad repeat 1: Insight into the gp120-gp41 interaction
    • Sen J, Yan T, Wang J, et al. Alanine scanning mutagenesis of HIV-1 gp41 heptad repeat 1: insight into the gp120-gp41 interaction. Biochemistry 2010; 49: 5057-65.
    • (2010) Biochemistry , vol.49 , pp. 5057-5065
    • Sen, J.1    Yan, T.2    Wang, J.3
  • 90
    • 33144486096 scopus 로고    scopus 로고
    • Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1
    • Moore PL, Crooks ET, Porter L, et al. Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1. J Virol 2006; 80: 2515-28.
    • (2006) J Virol , vol.80 , pp. 2515-2528
    • Moore, P.L.1    Crooks, E.T.2    Porter, L.3
  • 91
    • 2942588906 scopus 로고    scopus 로고
    • Mathematical and computational models of immune-receptor signalling
    • Goldstein B, Faeder JR, Hlavacek WS. Mathematical and computational models of immune-receptor signalling. Nat Rev Immunol 2004; 4: 445-56.
    • (2004) Nat Rev Immunol , vol.4 , pp. 445-456
    • Goldstein, B.1    Faeder, J.R.2    Hlavacek, W.S.3
  • 92
    • 34248157158 scopus 로고    scopus 로고
    • Insights into immunoglobulin E receptor signaling from structurally defined ligands
    • Holowka D, Sil D, Torigoe C, Baird B. Insights into immunoglobulin E receptor signaling from structurally defined ligands. Immunol Rev 2007; 217: 269-79.
    • (2007) Immunol Rev , vol.217 , pp. 269-279
    • Holowka, D.1    Sil, D.2    Torigoe, C.3    Baird, B.4
  • 93
    • 0019429017 scopus 로고
    • Configurations of a polymeric antigen adsorbed to a B-cell membrane
    • Wiegel FW, Perelson AS. Configurations of a polymeric antigen adsorbed to a B-cell membrane. J Theor Biol 1981; 88: 533-68.
    • (1981) J Theor Biol , vol.88 , pp. 533-568
    • Wiegel, F.W.1    Perelson, A.S.2
  • 94
    • 30844465687 scopus 로고    scopus 로고
    • A simplified method for the rapid fluorometric assessment of antibody-dependent cell-mediated cytotoxicity
    • Gomez-Roman VR, Florese RH, Patterson LJ, et al. A simplified method for the rapid fluorometric assessment of antibody-dependent cell-mediated cytotoxicity. J Immunol Methods 2006; 308: 53-67.
    • (2006) J Immunol Methods , vol.308 , pp. 53-67
    • Gomez-Roman, V.R.1    Florese, R.H.2    Patterson, L.J.3
  • 95
    • 79960555557 scopus 로고    scopus 로고
    • High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses
    • Pollara J, Hart L, Brewer F, et al. High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses. Cytometry A 2011; 79: 603-12.
    • (2011) Cytometry A , vol.79 , pp. 603-612
    • Pollara, J.1    Hart, L.2    Brewer, F.3
  • 96
    • 0030911709 scopus 로고    scopus 로고
    • Dimeric association and segmental variability in the structure of human CD4
    • Wu H, Kwong PD, Hendrickson WA. Dimeric association and segmental variability in the structure of human CD4. Nature 1997; 387: 527-30.
    • (1997) Nature , vol.387 , pp. 527-530
    • Wu, H.1    Kwong, P.D.2    Hendrickson, W.A.3
  • 97
    • 0036885014 scopus 로고    scopus 로고
    • CD4 dimers constitute the functional component required for T cell activation
    • Moldovan MC, Yachou A, Levesque K, et al. CD4 dimers constitute the functional component required for T cell activation. J Immunol 2002; 169: 6261-8.
    • (2002) J Immunol , vol.169 , pp. 6261-6268
    • Moldovan, M.C.1    Yachou, A.2    Levesque, K.3
  • 98
    • 78649462789 scopus 로고    scopus 로고
    • Reduced monomeric CD4 is the preferred receptor for HIV
    • Matthias LJ, Azimi I, Tabrett CA, Hogg PJ. Reduced monomeric CD4 is the preferred receptor for HIV. J Biol Chem 2010; 285: 40793-9.
    • (2010) J Biol Chem , vol.285 , pp. 40793-40799
    • Matthias, L.J.1    Azimi, I.2    Tabrett, C.A.3    Hogg, P.J.4
  • 99
    • 84880344549 scopus 로고    scopus 로고
    • Antigen-antibody interactions and monoclonal antibodies
    • In: W E Paul, Ed, New York: Lipincott Williams & Wilkins
    • Berzofsky JA, Berkower IJ. Antigen-antibody interactions and monoclonal antibodies. In: W E Paul, Ed. Fundamental Immunology. New York: Lipincott Williams & Wilkins 2013; 183-214.
    • (2013) Fundamental Immunology , pp. 183-214
    • Berzofsky, J.A.1    Berkower, I.J.2
  • 100
    • 84855382987 scopus 로고    scopus 로고
    • Optimizing properties of antireceptor antibodies using kinetic computational models and experiments
    • Harms BD, Kearns JD, Su SV, et al. Optimizing properties of antireceptor antibodies using kinetic computational models and experiments. Methods Enzymol 2012; 502: 67-87.
    • (2012) Methods Enzymol , vol.502 , pp. 67-87
    • Harms, B.D.1    Kearns, J.D.2    Su, S.V.3
  • 101
    • 0015313012 scopus 로고
    • The influence of polyvalency on the binding properties of antibodies
    • Crothers DM, Metzger H. The influence of polyvalency on the binding properties of antibodies. Immunochemistry 1972; 9: 341-57.
    • (1972) Immunochemistry , vol.9 , pp. 341-357
    • Crothers, D.M.1    Metzger, H.2
  • 102
    • 0017109014 scopus 로고
    • The kinetics of aggregation phenomena. I. Minimal models for patch formation of lymphocyte membranes
    • DeLisi C, Perelson A. The kinetics of aggregation phenomena. I. Minimal models for patch formation of lymphocyte membranes. J Theor Biol 1976; 62: 159-210.
    • (1976) J Theor Biol , vol.62 , pp. 159-210
    • DeLisi, C.1    Perelson, A.2
  • 103
    • 0028931731 scopus 로고
    • The kinetics of bivalent ligandbivalent receptor aggregation: Ring formation and the breakdown of the equivalent site approximation
    • Posner RG, Wofsy C, Goldstein B. The kinetics of bivalent ligandbivalent receptor aggregation: ring formation and the breakdown of the equivalent site approximation. Math Biosci 1995; 126: 171-90.
    • (1995) Math Biosci , vol.126 , pp. 171-190
    • Posner, R.G.1    Wofsy, C.2    Goldstein, B.3
  • 104
    • 0018102209 scopus 로고
    • Histamine release due to bivalent penicilloyl haptens: Control by the basophil plasma membrane
    • Dembo M, Goldstein B, Sobotka AK, Lichtenstein LM. Histamine release due to bivalent penicilloyl haptens: control by the basophil plasma membrane. J Immunol 1978; 121: 354-8.
    • (1978) J Immunol , vol.121 , pp. 354-358
    • Dembo, M.1    Goldstein, B.2    Sobotka, A.K.3    Lichtenstein, L.M.4
  • 105
    • 0000783773 scopus 로고
    • The Protective Action of Type I Antipneumococcus Serum in Mice: I. The Quantitative Aspects of the Mouse Protection Test
    • Goodner K, Horsfall FL. The Protective Action of Type I Antipneumococcus Serum in Mice: I. The Quantitative Aspects of the Mouse Protection Test. J Exp Med 1935; 62: 359-74.
    • (1935) J Exp Med , vol.62 , pp. 359-374
    • Goodner, K.1    Horsfall, F.L.2
  • 106
    • 33747828969 scopus 로고
    • The Protective Action of Type I Antipneumococcus Serum in Mice: Iv. The Prozone
    • Goodner K, Horsfall FL. The Protective Action of Type I Antipneumococcus Serum in Mice: Iv. The Prozone. J Exp Med 1936; 64: 369-75.
    • (1936) J Exp Med , vol.64 , pp. 369-375
    • Goodner, K.1    Horsfall, F.L.2
  • 107
    • 0014837934 scopus 로고
    • Contactual lysis of antibody-coated chicken erythrocytes by purified lymphocytes
    • Perlmann P, Perlmann H. Contactual lysis of antibody-coated chicken erythrocytes by purified lymphocytes. Cell Immunol 1970; 1: 300-15.
    • (1970) Cell Immunol , vol.1 , pp. 300-315
    • Perlmann, P.1    Perlmann, H.2
  • 108
    • 70350320582 scopus 로고    scopus 로고
    • Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region
    • Gray ES, Madiga MC, Moore PL, et al. Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region. J Virol 2009; 83: 11265-74.
    • (2009) J Virol , vol.83 , pp. 11265-11274
    • Gray, E.S.1    Madiga, M.C.2    Moore, P.L.3
  • 109
    • 69249208675 scopus 로고    scopus 로고
    • Antibody specificities associated with neutralization breadth in plasma from HIV-1 subtype C infected blood donors
    • Gray ES, Taylor N, Wycuff D, et al. Antibody specificities associated with neutralization breadth in plasma from HIV-1 subtype C infected blood donors. J Virol 2009; 83(17): 8925-37.
    • (2009) J Virol , vol.83 , Issue.17 , pp. 8925-8937
    • Gray, E.S.1    Taylor, N.2    Wycuff, D.3
  • 110
    • 69249208675 scopus 로고    scopus 로고
    • Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors
    • Gray ES, Taylor N, Wycuff D, et al. Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors. J Virol 2009; 83: 8925-37.
    • (2009) J Virol , vol.83 , pp. 8925-8937
    • Gray, E.S.1    Taylor, N.2    Wycuff, D.3
  • 111
    • 0035253378 scopus 로고    scopus 로고
    • Immunoglobulin M efficacy against Cryptococcus neoformans: Mechanism, dose dependence, and prozonelike effects in passive protection experiments
    • Taborda CP, Casadevall A. Immunoglobulin M efficacy against Cryptococcus neoformans: mechanism, dose dependence, and prozonelike effects in passive protection experiments. J Immunol 2001; 166: 2100-7.
    • (2001) J Immunol , vol.166 , pp. 2100-2107
    • Taborda, C.P.1    Casadevall, A.2
  • 112
    • 0037378911 scopus 로고    scopus 로고
    • More is not necessarily better: Prozone-like effects in passive immunization with IgG
    • Taborda CP, Rivera J, Zaragoza O, Casadevall A. More is not necessarily better: prozone-like effects in passive immunization with IgG. J Immunol 2003; 170: 3621-30.
    • (2003) J Immunol , vol.170 , pp. 3621-3630
    • Taborda, C.P.1    Rivera, J.2    Zaragoza, O.3    Casadevall, A.4
  • 113
    • 0033059349 scopus 로고    scopus 로고
    • Quantifying aggregation of IgE-FcepsilonRI by multivalent antigen
    • Hlavacek WS, Perelson AS, Sulzer B, et al. Quantifying aggregation of IgE-FcepsilonRI by multivalent antigen. Biophys J 1999; 76: 2421-31.
    • (1999) Biophys J , vol.76 , pp. 2421-2431
    • Hlavacek, W.S.1    Perelson, A.S.2    Sulzer, B.3
  • 114
    • 0345471066 scopus 로고    scopus 로고
    • Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120
    • Veazey RS, Shattock RJ, Pope M, et al. Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120. Nat Med 2003; 9: 343-6.
    • (2003) Nat Med , vol.9 , pp. 343-346
    • Veazey, R.S.1    Shattock, R.J.2    Pope, M.3
  • 115
    • 84865068814 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding
    • Smalls-Mantey A, Doria-Rose N, Klein R, et al. Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding. J Virol 2012; 86: 8672-80.
    • (2012) J Virol , vol.86 , pp. 8672-8680
    • Smalls-Mantey, A.1    Doria-Rose, N.2    Klein, R.3


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