PECAM-1 and caveolae form the mechanosensing complex necessary for NOX2 activation and angiogenic signaling with stopped flow in pulmonary endothelium

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 305, Issue 11, 2013, Pages

  Noel, John ^a   Wang, Hui ^a   Hong, Nankang ^a   Tao, Jian Qin ^a   Yu, Kevin ^a   Sorokina, Elena M ^a   DeBolt, Kristine ^a   Heayn, Michelle ^a   Rizzo, Victor ^b   Delisser, Horace ^b   Fisher, Aron B ^a   Chatterjee, Shampa ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenic potential; Katp (Kir6.2) channel; Mechanotransduction; NOX2; PECAM; Pulmonary endothelium; Stop of flow

Indexed keywords

CAVEOLIN 1; CD31 ANTIGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CAVEOLA; CONTROLLED STUDY; FORCE; IN VITRO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG BLOOD FLOW; MECHANOTRANSDUCTION; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANGIOGENIC POTENTIAL; KATP (KIR6.2) CHANNEL; MECHANOTRANSDUCTION; NOX2; PECAM; PULMONARY ENDOTHELIUM; STOP OF FLOW;

ANGIOPOIETIN-2; ANIMALS; ANTIGENS, CD31; CAVEOLAE; CAVEOLIN 1; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; GENE EXPRESSION; LUNG; MALE; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROVESSELS; NADPH OXIDASE; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; REGIONAL BLOOD FLOW; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84889030864     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00123.2013     Document Type: Article

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