Genetic dissection of the polyoxin building block-carbamoylpolyoxamic acid biosynthesis revealing the " pathway redundancy" in metabolic networks

Microbial Cell Factories

Volumn 12, Issue 1, 2013, Pages

  Chen, Wenqing ^a,b,c,d   Dai, Daofeng ^c   Wang, Changchun ^a   Huang, Tingting ^c   Zhai, Lipeng ^c   Deng, Zixin ^a,c  

^a WUHAN UNIVERSITY   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c Shanghai Jiao Tong University   (China)

^d University of California   (United States)

Author keywords

Building block; Carbamoylpolyoxamic acid; Metabolic networks; Pathway redundancy; Polyoxin

Indexed keywords

ACETYLGLUTAMATE KINASE; AMINO ACID ACETYLTRANSFERASE; ANTIBIOTIC AGENT; ARGININE; CARBAMOYLPOLYOXAMIC ACID; CARBAMOYLTRANSFERASE; N ACETYLGLUTAMIC ACID; NUCLEOSIDE; OXIDOREDUCTASE; PHOSPHOTRANSFERASE; POLYOXIMIC ACID; POLYOXIN; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVITY; FRANKIA; FRANKIA ALNI; GENE MUTATION; METABOLIC PARAMETERS; METABOLISM; MUTANT; NEISSERIA MUCOSA; NONHUMAN; PROTEIN FUNCTION; PSEUDOMONAS AERUGINOSA; SINORHIZOBIUM; STREPTOMYCES; STREPTOMYCES COELICOLOR; STREPTOMYCES PRISTINAESPIRALIS; TRICHOSPORON CUTANEUM;

AMINO ACID SEQUENCE; COMPUTER SIMULATION; METABOLIC NETWORKS AND PATHWAYS; MOLECULAR SEQUENCE DATA; OXAMIC ACID; PYRIMIDINE NUCLEOSIDES;

EID: 84889025816     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-12-121     Document Type: Article

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