Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cells

Free Radical Biology and Medicine

Volumn 67, Issue , 2014, Pages 265-277

  Speckmann, Bodo ^a   Gerloff, Kirsten ^b,c   Simms, Lisa ^a   Oancea, Iulia ^b,c   Shi, Wei ^a   McGuckin, Michael A ^b,c   Radford Smith, Graham ^a,d,e   Khanna, Kum Kum ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b Immunity   (Australia)

^c TRANSLATIONAL RESEARCH INSTITUTE   (Australia)

^d UNIVERSITY OF QUEENSLAND   (Australia)

^e ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

Colitis; Crohn's disease; ER stress; Free radicals; Selenoprotein; Tunicamycin

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALNEXIN; GLUCOSE REGULATED PROTEIN 78; INTERLEUKIN 8; MESSENGER RNA; MUCIN 2; PROTEIN P97; SELENIUM; SELENOPROTEIN; SELENOPROTEIN S; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; HYDROGEN PEROXIDE; TUNICAMYCIN; BIOLOGICAL MARKER; MEMBRANE PROTEIN; VIMP PROTEIN, HUMAN;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CLINICAL ARTICLE; COLON BIOPSY; COMPARATIVE STUDY; CONTROLLED STUDY; CROHN DISEASE; ENDOPLASMIC RETICULUM STRESS; EXPERIMENTAL MOUSE; FEMALE; GENE SILENCING; GENETIC ASSOCIATION; GOBLET CELL; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INTESTINE CELL; INTESTINE EPITHELIUM; INTESTINE EPITHELIUM CELL; INTESTINE FUNCTION; INTRACELLULAR SIGNALING; LAMINA PROPRIA; LARGE INTESTINE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; REPORTER GENE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMALL INTESTINE; TISSUE SECTION; ULCERATIVE COLITIS; UNFOLDED PROTEIN RESPONSE; UPREGULATION; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; C57BL 6 MOUSE; CACO 2 CELL LINE; DIET SUPPLEMENTATION; ENTERITIS; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; INFLAMMATORY BOWEL DISEASE; INTESTINE BIOPSY; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN FUNCTION; RISK FACTOR; WESTERN BLOTTING; ANIMAL; BIOPSY; CELL LINE; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION; GENETICS; INTESTINE; METABOLISM; PATHOLOGY;

MUS;

ANIMALS; BIOLOGICAL MARKERS; BIOPSY; CALNEXIN; CELL LINE; CROHN DISEASE; ENDOPLASMIC RETICULUM STRESS; EPITHELIAL CELLS; GENE EXPRESSION; HUMANS; INTESTINES; MACROPHAGES; MEMBRANE PROTEINS; MICE; PANETH CELLS; SELENOPROTEINS; TUNICAMYCIN;

EID: 84889018593     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.11.001     Document Type: Article

References (42)

1. J.K. Hou, B. Abraham, and H. El-Serag Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature Am. J. Gastroenterol. 106 2011 563 573
2. B. Khor, A. Gardet, and R.J. Xavier Genetics and pathogenesis of inflammatory bowel disease Nature 474 2011 307 317
3. S. Krehl, M. Loewinger, S. Florian, A.P. Kipp, A. Banning, L.A. Wessjohann, M.N. Brauer, R. Iori, R.S. Esworthy, F.F. Chu, and R. Brigelius-Flohe Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply Carcinogenesis 33 2012 620 628
4. O. Tirosh, E. Levy, and R. Reifen High selenium diet protects against TNBS-induced acute inflammation, mitochondrial dysfunction, and secondary necrosis in rat colon Nutrition 23 2007 878 886 (Pubitemid 47542368)
5. C.W. Barrett, K. Singh, A.K. Motley, M.K. Lintel, E. Matafonova, A.M. Bradley, W. Ning, S.V. Poindexter, B. Parang, V.K. Reddy, R. Chaturvedi, B.M. Fingleton, M.K. Washington, K.T. Wilson, S.S. Davies, K.E. Hill, R.F. Burk, and C.S. Williams Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis PLoS One 8 2013 e67845
6. E. Schoenmakers, M. Agostini, C. Mitchell, N. Schoenmakers, L. Papp, O. Rajanayagam, R. Padidela, L. Ceron-Gutierrez, R. Doffinger, C. Prevosto, J. Luan, S. Montano, J. Lu, M. Castanet, N. Clemons, M. Groeneveld, P. Castets, M. Karbaschi, S. Aitken, A. Dixon, J. Williams, I. Campi, M. Blount, H. Burton, F. Muntoni, D. O'Donovan, A. Dean, A. Warren, C. Brierley, D. Baguley, P. Guicheney, R. Fitzgerald, A. Coles, H. Gaston, P. Todd, A. Holmgren, K.K. Khanna, M. Cooke, R. Semple, D. Halsall, N. Wareham, J. Schwabe, L. Grasso, P. Beck-Peccoz, A. Ogunko, M. Dattani, M. Gurnell, and K. Chatterjee Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans J. Clin. Invest. 120 2010 4220 4235
7. R. Irons, B.A. Carlson, D.L. Hatfield, and C.D. Davis Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression J. Nutr. 136 2006 1311 1317
8. R.S. Esworthy, R. Aranda, M.G. Martin, J.H. Doroshow, S.W. Binder, and F.F. Chu Mice with combined disruption of Gpx1 and Gpx2 genes have colitis Am. J. Physiol. Gastrointest. Liver Physiol. 281 2001 G848 G855
9. G.V. Kryukov, S. Castellano, S.V. Novoselov, A.V. Lobanov, O. Zehtab, R. Guigo, and V.N. Gladyshev Characterization of mammalian selenoproteomes Science 300 2003 1439 1443 (Pubitemid 36638165)
10. Y. Murawaki, H. Tsuchiya, T. Kanbe, K. Harada, K. Yashima, K. Nozaka, O. Tanida, M. Kohno, T. Mukoyama, E. Nishimuki, H. Kojo, T. Matsura, K. Takahashi, M. Osaki, H. Ito, J. Yodoi, and G. Shiota Aberrant expression of selenoproteins in the progression of colorectal cancer Cancer Lett. 259 2008 218 230 (Pubitemid 350258671)
11. B. Speckmann, H.J. Bidmon, A. Pinto, M. Anlauf, H. Sies, and H. Steinbrenner Induction of glutathione peroxidase 4 expression during enterocytic cell differentiation J. Biol. Chem. 286 2011 10764 10772
12. P.A. Tsuji, B.A. Carlson, S. Naranjo-Suarez, M.H. Yoo, X.M. Xu, D.E. Fomenko, V.N. Gladyshev, D.L. Hatfield, and C.D. Davis Knockout of the 15 kDa selenoprotein protects against chemically-induced aberrant crypt formation in mice PLoS One 7 2012 e50574
13. J.E. Curran, J.B. Jowett, K.S. Elliott, Y. Gao, K. Gluschenko, J. Wang, D.M. Abel Azim, G. Cai, M.C. Mahaney, A.G. Comuzzie, T.D. Dyer, K.R. Walder, P. Zimmet, J.W. MacCluer, G.R. Collier, A.H. Kissebah, and J. Blangero Genetic variation in selenoprotein S influences inflammatory response Nat. Genet. 37 2005 1234 1241 (Pubitemid 41568706)
14. M. Olsson, B. Olsson, P. Jacobson, D.S. Thelle, J. Bjorkegren, A. Walley, P. Froguel, L.M. Carlsson, and K. Sjoholm Expression of the selenoprotein S (SELS) gene in subcutaneous adipose tissue and SELS genotype are associated with metabolic risk factors Metabolism 60 2011 114 120
15. A.J. Cox, A.B. Lehtinen, J. Xu, C.D. Langefeld, B.I. Freedman, J.J. Carr, and D.W. Bowden Polymorphisms in the selenoprotein S gene and subclinical cardiovascular disease in the Diabetes Heart Study Acta Diabetol. 50 2013 391 399
16. Y. Ye, Y. Shibata, C. Yun, D. Ron, and T.A. Rapoport A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol Nature 429 2004 841 847 (Pubitemid 38843292)
17. M.A. McGuckin, R.D. Eri, I. Das, R. Lourie, and T.H. Florin ER stress and the unfolded protein response in intestinal inflammation Am. J. Physiol. Gastrointest. Liver Physiol. 298 2010 G820 G832
18. N. Fradejas, C. Serrano-Perez Mdel, P. Tranque, and S. Calvo Selenoprotein S expression in reactive astrocytes following brain injury Glia 59 2011 959 972
19. K.H. Kim, Y. Gao, K. Walder, G.R. Collier, J. Skelton, and A.H. Kissebah SEPS1 protects RAW264.7 cells from pharmacological ER stress agent-induced apoptosis Biochem. Biophys. Res. Commun. 354 2007 127 132 (Pubitemid 46123211)
20. V.M. Labunskyy, M.H. Yoo, D.L. Hatfield, and V.N. Gladyshev Sep15, a thioredoxin-like selenoprotein, is involved in the unfolded protein response and differentially regulated by adaptive and acute ER stresses Biochemistry 48 2009 8458 8465
21. A. Kaser, A.H. Lee, A. Franke, J.N. Glickman, S. Zeissig, H. Tilg, E.E. Nieuwenhuis, D.E. Higgins, S. Schreiber, L.H. Glimcher, and R.S. Blumberg XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease Cell 134 2008 743 756
22. C.K. Heazlewood, M.C. Cook, R. Eri, G.R. Price, S.B. Tauro, D. Taupin, D.J. Thornton, C.W. Png, T.L. Crockford, R.J. Cornall, R. Adams, M. Kato, K.A. Nelms, N.A. Hong, T.H. Florin, C.C. Goodnow, and M.A. McGuckin Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis PLoS Med. 5 2008 e54
23. J. Liu, F. Li, and S. Rozovsky The intrinsically disordered membrane protein selenoprotein S is a reductase in vitro Biochemistry 52 2013 3051 3061
24. L.C. Christensen, N.W. Jensen, A. Vala, J. Kamarauskaite, L. Johansson, J.R. Winther, K. Hofmann, K. Teilum, and L. Ellgaard The human selenoprotein VCP-interacting membrane protein (VIMP) is non-globular and harbors a reductase function in an intrinsically disordered region J. Biol. Chem. 287 2012 26388 26399
25. V.A. Shchedrina, Y. Zhang, V.M. Labunskyy, D.L. Hatfield, and V.N. Gladyshev Structure-function relations, physiological roles, and evolution of mammalian ER-resident selenoproteins Antioxid. Redox Signaling 12 2010 839 849
26. Y. Gao, H.C. Feng, K. Walder, K. Bolton, T. Sunderland, N. Bishara, M. Quick, L. Kantham, and G.R. Collier Regulation of the selenoprotein SelS by glucose deprivation and endoplasmic reticulum stress - SelS is a novel glucose-regulated protein FEBS Lett. 563 2004 185 190 (Pubitemid 38471596)
27. J. Zeng, S. Du, J. Zhou, and K. Huang Role of SelS in lipopolysaccharide-induced inflammatory response in hepatoma HepG2 cells Arch. Biochem. Biophys. 478 2008 1 6
28. T. Iwawaki, R. Akai, K. Kohno, and M. Miura A transgenic mouse model for monitoring endoplasmic reticulum stress Nat. Med. 10 2004 98 102 (Pubitemid 38524705)
29. M. Amarzguioui, P. Lundberg, E. Cantin, J. Hagstrom, M.A. Behlke, and J.J. Rossi Rational design and in vitro and in vivo delivery of Dicer substrate siRNA Nat. Protoc. 1 2006 508 517
30. L.A. Simms, J.D. Doecke, M.D. Walsh, N. Huang, E.V. Fowler, and G.L. Radford-Smith Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease Gut 57 2008 903 910 (Pubitemid 351919524)
31. M.W. Pfaffl A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res. 29 2001 e45
32. N. Kitsera, A. Khobta, and B. Epe Destabilized green fluorescent protein detects rapid removal of transcription blocks after genotoxic exposure Biotechniques 43 2007 222 227 (Pubitemid 47255056)
33. J.M. Mariadason, D. Arango, G.A. Corner, M.J. Aranes, K.A. Hotchkiss, W. Yang, and L.H. Augenlicht A gene expression profile that defines colon cell maturation in vitro Cancer Res. 62 2002 4791 4804
34. B. Speckmann, A. Pinto, M. Winter, I. Forster, H. Sies, and H. Steinbrenner Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction Free Radic. Biol. Med. 49 2010 777 785
35. C. Hetz, and L.H. Glimcher Fine-tuning of the unfolded protein response: assembling the IRE1alpha interactome Mol. Cell 35 2009 551 561
36. A.M. Benham, A. Cabibbo, A. Fassio, N. Bulleid, R. Sitia, and I. Braakman The CXXCXXC motif determines the folding, structure and stability of human Ero1-Lalpha EMBO J. 19 2000 4493 4502
37. S. Florian, S. Krehl, M. Loewinger, A. Kipp, A. Banning, S. Esworthy, F.F. Chu, and R. Brigelius-Flohe Loss of GPx2 increases apoptosis, mitosis, and GPx1 expression in the intestine of mice Free Radic. Biol. Med. 49 2010 1694 1702
38. A.P. Kipp, M.F. Muller, E.M. Goken, S. Deubel, and R. Brigelius-Flohe The selenoproteins GPx2, TrxR2 and TrxR3 are regulated by Wnt signalling in the intestinal epithelium Biochim. Biophys. Acta 1820 2012 1588 1596
39. K. Wingler, C. Muller, K. Schmehl, S. Florian, and R. Brigelius-Flohe Gastrointestinal glutathione peroxidase prevents transport of lipid hydroperoxides in CaCo-2 cells Gastroenterology 119 2000 420 430 (Pubitemid 30621992)
40. S. Du, H. Liu, and K. Huang Influence of SelS gene silence on beta-mercaptoethanol-mediated endoplasmic reticulum stress and cell apoptosis in HepG2 cells Biochim. Biophys. Acta 1800 2010 511 517
41. K.P. Pavlick, F.S. Laroux, J. Fuseler, R.E. Wolf, L. Gray, J. Hoffman, and M.B. Grisham Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease Free Radic. Biol. Med. 33 2002 311 322 (Pubitemid 34786271)
42. J. Seiderer, J. Dambacher, B. Kuhnlein, S. Pfennig, A. Konrad, H.P. Torok, D. Haller, B. Goke, T. Ochsenkuhn, P. Lohse, and S. Brand The role of the selenoprotein S (SELS) gene -105G>A promoter polymorphism in inflammatory bowel disease and regulation of SELS gene expression in intestinal inflammation Tissue Antigens 70 2007 238 246 (Pubitemid 47106655)