Knockout of the 15 kDa Selenoprotein Protects against Chemically-Induced Aberrant Crypt Formation in Mice

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Tsuji, Petra A ^a,b   Carlson, Bradley A ^b   Naranjo Suarez, Salvador ^b   Yoo, Min Hyuk ^b   Xu, Xue Ming ^b   Fomenko, Dmitri E ^c   Gladyshev, Vadim N ^d   Hatfield, Dolph L ^b   Davis, Cindy D ^b  

^a TOWSON UNIVERSITY   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; BETA CATENIN; GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN 1; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA; SELENIUM; SELENOPROTEIN; UNCLASSIFIED DRUG;

ABERRANT CRYPT FOCUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON MUCOSA; COLORECTAL CANCER; CONTROLLED STUDY; GENE EXPRESSION; HOMOZYGOSITY; KNOCKOUT MOUSE; MALE; MICROARRAY ANALYSIS; MOUSE; MUCOSA CELL; NONHUMAN; PROTECTION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; UPREGULATION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; BASE SEQUENCE; BETA CATENIN; BLOTTING, WESTERN; COLONIC NEOPLASMS; CYTOKINES; DNA PRIMERS; GENE EXPRESSION PROFILING; INTESTINAL MUCOSA; MALE; MICE; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; SELENOPROTEINS;

MURINAE; MUS;

EID: 84870762625     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050574     Document Type: Article

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