메뉴 건너뛰기




Volumn 34, Issue 11, 2013, Pages 1145-1150

Silibinin improves the cytotoxicity of methotrexate in chemo resistant human rhabdomyosarcoma cell lines

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE; SILIBININ; TETRAZOLIUM;

EID: 84888878711     PISSN: 03795284     EISSN: 16583175     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (41)
  • 1
    • 0025739785 scopus 로고
    • Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis
    • Weinstein RS, Jakate SM, Dominguez JM. Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis. Cancer Res 1991; 51: 2720-2726.
    • (1991) Cancer Res , vol.51 , pp. 2720-2726
    • Weinstein, R.S.1    Jakate, S.M.2    Dominguez, J.M.3
  • 2
    • 0035300589 scopus 로고    scopus 로고
    • Progression and enhancement of metastatic potential after exposure of tumor cells to chemotherapeutic agents
    • De Larco JE, Wuertz BR, Manivel JC. Progression and enhancement of metastatic potential after exposure of tumor cells to chemotherapeutic agents. Cancer Res 2001; 61: 2857-2861.
    • (2001) Cancer Res , vol.61 , pp. 2857-2861
    • De Larco, J.E.1    Wuertz, B.R.2    Manivel, J.C.3
  • 3
    • 0027351189 scopus 로고
    • Karnofsky memorial lecture: Ode to methotrexate
    • Bertino JR. Karnofsky memorial lecture: ode to methotrexate. J Clin Oncol 1993; 11: 5-14.
    • (1993) J Clin Oncol , vol.11 , pp. 5-14
    • Bertino, J.R.1
  • 4
    • 0030462249 scopus 로고    scopus 로고
    • Molecular therapeutics: Methotrexate and its mechanism of action
    • Cronstein BN. Molecular therapeutics: methotrexate and its mechanism of action. Arthritis Rheum 1996; 39: 1951-1960.
    • (1996) Arthritis Rheum , vol.39 , pp. 1951-1960
    • Cronstein, B.N.1
  • 5
    • 0021356277 scopus 로고
    • Synthesis and properties of 7-hydroxymethotrexate polyglutamyl derivatives in Ehrlich ascites tumor cells in vitro
    • Fabre G, Fabre I, Matherly LH, Cano JP, Goldman ID. Synthesis and properties of 7-hydroxymethotrexate polyglutamyl derivatives in Ehrlich ascites tumor cells in vitro. J Biol Chem 1984; 259: 5066-5072.
    • (1984) J Biol Chem , vol.259 , pp. 5066-5072
    • Fabre, G.1    Fabre, I.2    Matherly, L.H.3    Cano, J.P.4    Goldman, I.D.5
  • 6
    • 0020565471 scopus 로고
    • In vitro formation of polyglutamyl derivatives of methotrexate and 7-hydroxymethotrexate in human lymphoblastic leukemia cells
    • Fabre G, Matherly LH, Favre R, Catalin J, Cano JP. In vitro formation of polyglutamyl derivatives of methotrexate and 7-hydroxymethotrexate in human lymphoblastic leukemia cells. Cancer Res 1983; 43: 4648-4652.
    • (1983) Cancer Res , vol.43 , pp. 4648-4652
    • Fabre, G.1    Matherly, L.H.2    Favre, R.3    Catalin, J.4    Cano, J.P.5
  • 7
    • 0033754628 scopus 로고    scopus 로고
    • Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukemia
    • Rots MG, Pieters R, Kaspers GJ, Veerman AJ, Peters GJ, Jansen G. Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukemia. Br J Haematol 2000; 110: 791-800.
    • (2000) Br J Haematol , vol.110 , pp. 791-800
    • Rots, M.G.1    Pieters, R.2    Kaspers, G.J.3    Veerman, A.J.4    Peters, G.J.5    Jansen, G.6
  • 8
    • 0032807982 scopus 로고    scopus 로고
    • Carrier-mediated membrane transport of folates in mammalian cells
    • Sirotnak FM, Tolner B. Carrier-mediated membrane transport of folates in mammalian cells. Annu Rev Nutr 1999; 19: 91-122.
    • (1999) Annu Rev Nutr , vol.19 , pp. 91-122
    • Sirotnak, F.M.1    Tolner, B.2
  • 9
    • 0041842584 scopus 로고    scopus 로고
    • Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate
    • Stark M, Rothem L, Jansen G, Scheffer GL, Goldman ID, Assaraf YG. Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate. Mol Pharmacol 2003; 64: 220-227.
    • (2003) Mol Pharmacol , vol.64 , pp. 220-227
    • Stark, M.1    Rothem, L.2    Jansen, G.3    Scheffer, G.L.4    Goldman, I.D.5    Assaraf, Y.G.6
  • 10
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh YJ. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003; 3: 768-780.
    • (2003) Nat Rev Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 11
    • 0024321992 scopus 로고
    • Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver
    • Ferenci P, Dragosics B, Dittrich H, Frank H, Benda L, Lochs H, et al. Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatol 1989; 9: 105-113.
    • (1989) J Hepatol , vol.9 , pp. 105-113
    • Ferenci, P.1    Dragosics, B.2    Dittrich, H.3    Frank, H.4    Benda, L.5    Lochs, H.6
  • 12
    • 28544439164 scopus 로고    scopus 로고
    • Silibinin efficacy against human hepatocellular carcinoma
    • Varghese L, Agarwal C, Tyagi A. Silibinin efficacy against human hepatocellular carcinoma. Clin Cancer Res 2005; 11: 8441-8448.
    • (2005) Clin Cancer Res , vol.11 , pp. 8441-8448
    • Varghese, L.1    Agarwal, C.2    Tyagi, A.3
  • 13
    • 33244472101 scopus 로고    scopus 로고
    • Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: A comparison of flavanone silibinin with flavanolignan mixture silymarin
    • Deep G, Singh RP, Agarwal C, Kroll DJ, Agarwal R. Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin. Oncogene 2006; 25: 1053-1069.
    • (2006) Oncogene , vol.25 , pp. 1053-1069
    • Deep, G.1    Singh, R.P.2    Agarwal, C.3    Kroll, D.J.4    Agarwal, R.5
  • 14
    • 3242786628 scopus 로고    scopus 로고
    • Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells
    • Tyagi AK, Agarwal C, Chan DC, Agarwal R. Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells. Oncol Rep 2004; 11: 493-499.
    • (2004) Oncol Rep , vol.11 , pp. 493-499
    • Tyagi, A.K.1    Agarwal, C.2    Chan, D.C.3    Agarwal, R.4
  • 15
    • 0043025262 scopus 로고    scopus 로고
    • Silibinin sensitizes human prostate carcinoma DU145 cells to cisplatin and carboplatin-induced growth inhibition and apoptotic death
    • Dhanalakshmi S, Agarwal P, Glode LM, Agarwal R. Silibinin sensitizes human prostate carcinoma DU145 cells to cisplatin and carboplatin-induced growth inhibition and apoptotic death. Int J Cancer 2003; 106: 699-705.
    • (2003) Int J Cancer , vol.106 , pp. 699-705
    • Dhanalakshmi, S.1    Agarwal, P.2    Glode, L.M.3    Agarwal, R.4
  • 16
    • 0036847718 scopus 로고    scopus 로고
    • Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced growth inhibition, G2-M arrest, and apoptosis
    • Tyagi AK, Singh RP, Agarwal C, Chan DC, Agarwal R. Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced growth inhibition, G2-M arrest, and apoptosis. Clin Cancer Res 2002; 8: 3512-3519.
    • (2002) Clin Cancer Res , vol.8 , pp. 3512-3519
    • Tyagi, A.K.1    Singh, R.P.2    Agarwal, C.3    Chan, D.C.4    Agarwal, R.5
  • 17
    • 33947195450 scopus 로고    scopus 로고
    • Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells
    • Flaig TW, Su LJ, Harrison G, Agarwal R, Glode LM. Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells. Int J Cancer 2007; 120: 2028-2033.
    • (2007) Int J Cancer , vol.120 , pp. 2028-2033
    • Flaig, T.W.1    Su, L.J.2    Harrison, G.3    Agarwal, R.4    Glode, L.M.5
  • 18
    • 0033936288 scopus 로고    scopus 로고
    • Characterization and modulation of drug resistance of human pediatric rhabdomyosarcoma cell lines
    • Cocker HA, Pinkerton CR, Kelland LR. Characterization and modulation of drug resistance of human pediatric rhabdomyosarcoma cell lines. Br J Cancer 2000; 83: 338-345.
    • (2000) Br J Cancer , vol.83 , pp. 338-345
    • Cocker, H.A.1    Pinkerton, C.R.2    Kelland, L.R.3
  • 19
    • 37349121900 scopus 로고    scopus 로고
    • Transcriptional regulation of aldo-ketoreductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: Role in the cell cycle and apoptosis
    • Selga E, Noe V, Ciudad CJ. Transcriptional regulation of aldo-ketoreductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis. Biochem Pharmacol 2008; 75: 414-426.
    • (2008) Biochem Pharmacol , vol.75 , pp. 414-426
    • Selga, E.1    Noe, V.2    Ciudad, C.J.3
  • 20
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 21
    • 33846981552 scopus 로고    scopus 로고
    • Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: A randomized phase III trial of the European Osteosarcoma Intergroup
    • Lewis IJ, Nooij MA, Whelan J, Sydes MR, Grimer R, Hogendoorn PC, et al. Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: a randomized phase III trial of the European Osteosarcoma Intergroup. J Natl Cancer Inst 2007; 99: 112-128.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 112-128
    • Lewis, I.J.1    Nooij, M.A.2    Whelan, J.3    Sydes, M.R.4    Grimer, R.5    Hogendoorn, P.C.6
  • 23
    • 35248859158 scopus 로고    scopus 로고
    • Effects and mechanisms of Silibinin on human hepatoma cell lines
    • Lah JJ, Cui W, Hu KQ. Effects and mechanisms of Silibinin on human hepatoma cell lines. World J Gastroenterol 2007; 13: 5299-5305.
    • (2007) World J Gastroenterol , vol.13 , pp. 5299-5305
    • Lah, J.J.1    Cui, W.2    Hu, K.Q.3
  • 24
    • 33646739493 scopus 로고    scopus 로고
    • Pilot study of oral silibinin, a putative chemopreventive agent, in colorectal cancer patients: Silibinin levels in plasma, colorectum, and liver and their pharmacodynamic consequences
    • Hoh C, Boocock D, Marczylo T, Singh R, Berry DP, Dennison AR, et al. Pilot study of oral silibinin, a putative chemopreventive agent, in colorectal cancer patients: silibinin levels in plasma, colorectum, and liver and their pharmacodynamic consequences. Clin Cancer Res 2006; 12: 2944-2950.
    • (2006) Clin Cancer Res , vol.12 , pp. 2944-2950
    • Hoh, C.1    Boocock, D.2    Marczylo, T.3    Singh, R.4    Berry, D.P.5    Dennison, A.R.6
  • 25
    • 82955187812 scopus 로고    scopus 로고
    • Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells
    • Kauntz H, Bousserouel S, Gosse F, Raul F. Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells. Apoptosis 2011; 16: 1042-1053.
    • (2011) Apoptosis , vol.16 , pp. 1042-1053
    • Kauntz, H.1    Bousserouel, S.2    Gosse, F.3    Raul, F.4
  • 26
    • 4544287556 scopus 로고    scopus 로고
    • Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages
    • Tyagi A, Agarwal C, Harrison G, Glode LM, Agarwal R. Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages. Carcinogenesis 2004; 25: 1711-1720.
    • (2004) Carcinogenesis , vol.25 , pp. 1711-1720
    • Tyagi, A.1    Agarwal, C.2    Harrison, G.3    Glode, L.M.4    Agarwal, R.5
  • 27
    • 79960009760 scopus 로고    scopus 로고
    • Quercetin induces apoptosis in the methotrexate-resistant osteosarcoma cell line U2-OS/MTX300 via mitochondrial dysfunction and dephosphorylation of Akt
    • Xie X, Yin J, Jia Q, Wang J, Zou C, Brewer KJ, et al. Quercetin induces apoptosis in the methotrexate-resistant osteosarcoma cell line U2-OS/MTX300 via mitochondrial dysfunction and dephosphorylation of Akt. Oncol Rep 2011; 26: 687-693.
    • (2011) Oncol Rep , vol.26 , pp. 687-693
    • Xie, X.1    Yin, J.2    Jia, Q.3    Wang, J.4    Zou, C.5    Brewer, K.J.6
  • 28
    • 44649155314 scopus 로고    scopus 로고
    • New combination therapies with cell-cycle agents
    • Deep G, Agarwal R. New combination therapies with cell-cycle agents. Curr Opin Invest Drugs 2008; 9: 591-604.
    • (2008) Curr Opin Invest Drugs , vol.9 , pp. 591-604
    • Deep, G.1    Agarwal, R.2
  • 30
    • 77957598340 scopus 로고    scopus 로고
    • Antimetastatic efficacy of silibinin: Molecular mechanisms and therapeutic potential against cancer
    • Deep G, Agarwal R. Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer. Cancer Metastasis Rev 2010; 29: 447-463.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 447-463
    • Deep, G.1    Agarwal, R.2
  • 31
    • 0029861534 scopus 로고    scopus 로고
    • Influence of methotrexate dose intensity on outcome of patients with high-grade osteogenic osteosarcoma. Analysis of the literature
    • Delepine N, Delepine G, Bacci G, Rosen G, Desbois JC. Influence of methotrexate dose intensity on outcome of patients with high-grade osteogenic osteosarcoma. Analysis of the literature. Cancer 1996; 78: 2127-2135.
    • (1996) Cancer , vol.78 , pp. 2127-2135
    • Delepine, N.1    Delepine, G.2    Bacci, G.3    Rosen, G.4    Desbois, J.C.5
  • 32
    • 27644439523 scopus 로고    scopus 로고
    • Mechanisms and preclinical efficacy of silibinin in preventing skin cancer
    • Singh RP, Agarwal R. Mechanisms and preclinical efficacy of silibinin in preventing skin cancer. Eur J Cancer 2005; 41: 1969-1979.
    • (2005) Eur J Cancer , vol.41 , pp. 1969-1979
    • Singh, R.P.1    Agarwal, R.2
  • 35
    • 42549155669 scopus 로고    scopus 로고
    • Silibinin restores paclitaxel sensitivity to paclitaxel-resistant human ovarian carcinoma cells
    • Zhou L, Liu P, Chen B, Wang Y, Wang X, Internati MC, et al. Silibinin restores paclitaxel sensitivity to paclitaxel-resistant human ovarian carcinoma cells. Anticancer Res 2008; 28: 1119-1127.
    • (2008) Anticancer Res , vol.28 , pp. 1119-1127
    • Zhou, L.1    Liu, P.2    Chen, B.3    Wang, Y.4    Wang, X.5    Internati, M.C.6
  • 36
    • 84875344694 scopus 로고    scopus 로고
    • Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc-/+ mice
    • Karim BO, Rhee KJ, Liu G, Zheng D, Huso DL. Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc-/+ mice. BMC Cancer 2013; 13: 157-167.
    • (2013) BMC Cancer , vol.13 , pp. 157-167
    • Karim, B.O.1    Rhee, K.J.2    Liu, G.3    Zheng, D.4    Huso, D.L.5
  • 37
    • 37549017366 scopus 로고    scopus 로고
    • Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice
    • Tyagi A, Raina K, Singh RP, Gu M, Agarwal C, Harrison G, et al. Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice. Mol Cancer Ther 2007; 6: 3248-3255.
    • (2007) Mol Cancer Ther , vol.6 , pp. 3248-3255
    • Tyagi, A.1    Raina, K.2    Singh, R.P.3    Gu, M.4    Agarwal, C.5    Harrison, G.6
  • 38
    • 37549009050 scopus 로고    scopus 로고
    • Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin
    • Singh RP, Tyagi A, Sharma G, Mohan S, Agarwal R. Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin. Clin Cancer Res 2008; 14: 300-308.
    • (2008) Clin Cancer Res , vol.14 , pp. 300-308
    • Singh, R.P.1    Tyagi, A.2    Sharma, G.3    Mohan, S.4    Agarwal, R.5
  • 39
    • 78751525898 scopus 로고    scopus 로고
    • Chemopreventive and chemotherapeutic effects of intravesical silibinin against bladder cancer by acting on mitochondria
    • Zeng J, Sun Y, Wu K, Li L, Zhang G, Yang Z, et al. Chemopreventive and chemotherapeutic effects of intravesical silibinin against bladder cancer by acting on mitochondria. Mol Cancer Ther 2011; 10: 104-116.
    • (2011) Mol Cancer Ther , vol.10 , pp. 104-116
    • Zeng, J.1    Sun, Y.2    Wu, K.3    Li, L.4    Zhang, G.5    Yang, Z.6
  • 40
    • 30344487254 scopus 로고    scopus 로고
    • Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs
    • Breedveld P, Beijnen JH, Schellens JH. Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs. Trends Pharmacol Sci 2006; 27: 17-24.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 17-24
    • Breedveld, P.1    Beijnen, J.H.2    Schellens, J.H.3
  • 41
    • 69949106198 scopus 로고    scopus 로고
    • Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy
    • Bansal T, Jaggi M, Khar RK, Talegaonkar S. Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy. J Pharm Pharm Sci 2009; 12: 46-78.
    • (2009) J Pharm Pharm Sci , vol.12 , pp. 46-78
    • Bansal, T.1    Jaggi, M.2    Khar, R.K.3    Talegaonkar, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.