Carbamazepine suppresses calpain-mediated autophagy impairment after ischemia/reperfusion in mouse livers

Toxicology and Applied Pharmacology

Volumn 273, Issue 3, 2013, Pages 600-610

  Kim, Jae Sung ^a   Wang, Jin Hee ^a   Biel, Thomas G ^a   Kim, Do Sung ^a   Flores Toro, Joseph A ^a   Vijayvargiya, Richa ^a   Zendejas, Ivan ^a   Behrns, Kevin E ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Autophagy; Calcium; Hepatocytes; Ischemia reperfusion; Mitochondria; Mitochondrial permeability transition

Indexed keywords

AUTOPHAGY PROTEIN 5; BECLIN 1; CALCIUM; CALPAIN; CARBAMAZEPINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; C57BL 6 MOUSE; CALCIUM CELL LEVEL; CELL DEATH; CELL INTERACTION; CELL ISOLATION; CELL PROTECTION; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER ISCHEMIA; LIVER REPERFUSION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MOUSE; MULTIPHOTON MICROSCOPY; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DEPLETION; REPERFUSION INJURY; TISSUE INJURY; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT OUTCOME;

ATG; AUTOPHAGY; AUTOPHAGY-RELATED PROTEINS; CALCIUM; CARBAMAZEPINE; CBZ; CHLOROQUINE; CQ; FDA; FOOD & DRUG ADMINISTRATION; HEPATOCYTES; I/R; INOSITOL-1,4,5-TRIPHOSPHATE; IP(3); ISCHEMIA/REPERFUSION; KREBS-RINGER-N-2 HYDROXYETHYLPIPERAZINE-N-2 ETHANESULFONIC ACID; KRH; LC3; MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; MITOCHONDRIA; MITOCHONDRIAL PERMEABILITY TRANSITION; MPT; PI; PROPIDIUM IODIDE; TETRAMETHYLRHODAMINE METHYLESTER; TMRM;

ANIMALS; ANTICONVULSANTS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CALCIUM; CALPAIN; CARBAMAZEPINE; HEPATOCYTES; LIVER; LYSOSOMES; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; REPERFUSION INJURY;

MUS;

EID: 84888870224     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.10.006     Document Type: Article

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