High capacity nanoporous silicon carrier for systemic delivery of gene silencing therapeutics

ACS Nano

Volumn 7, Issue 11, 2013, Pages 9867-9880

  Shen, Jianliang ^a,b   Xu, Rong ^a   Mai, Junhua ^a   Kim, Han Cheon ^a   Guo, Xiaojing ^a   Qin, Guoting ^a   Yang, Yong ^a   Wolfram, Joy ^a   Mu, Chaofeng ^a   Xia, Xiaojun ^a   Gu, Jianhua ^a   Liu, Xuewu ^a   Mao, Zong Wan ^b   Ferrari, Mauro ^a,c   Shen, Haifa ^a,c  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

cancer therapy; delivery; microRNA; porous silicon; siRNA

Indexed keywords

CANCER THERAPY; COLONY-STIMULATING FACTOR; DELIVERY; HUMAN BREAST CANCER CELLS; MICRORNAS; NANO-POROUS SILICON; SIRNA; SMALL INTERFERING RNA (SIRNA);

AMINO ACIDS; DISEASES; GENE EXPRESSION; GENETIC ENGINEERING; HISTOLOGY; POROUS SILICON; SILICON; STEM CELLS; TUMORS;

RNA;

ARGININE; HEAT SHOCK PROTEIN; MICRORNA; MOLECULAR CHAPERONE GRP78; NANOPARTICLE; POLYETHYLENEIMINE; SILICON; SMALL INTERFERING RNA; STAT3 PROTEIN; STAT3 PROTEIN, HUMAN;

ANIMAL; BREAST NEOPLASMS; CHEMISTRY; FEMALE; GENE EXPRESSION PROFILING; GENE SILENCING; GENETICS; HUMAN; KINETICS; MAMMARY NEOPLASMS, EXPERIMENTAL; METABOLISM; MOUSE; NANOMEDICINE; PROCEDURES; SCANNING ELECTRON MICROSCOPY; TUMOR CELL LINE;

ANIMALS; ARGININE; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION PROFILING; GENE SILENCING; HEAT-SHOCK PROTEINS; HUMANS; KINETICS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICRORNAS; MICROSCOPY, ELECTRON, SCANNING; NANOMEDICINE; NANOPARTICLES; POLYETHYLENEIMINE; RNA, SMALL INTERFERING; SILICON; STAT3 TRANSCRIPTION FACTOR;

MLCS; MLOWN;

EID: 84888868140     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn4035316     Document Type: Article

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