Design, synthesis and evaluation of 6-(4-((substituted-1H-1,2,3-triazol-4- yl)methyl)piperazin-1-yl)phenanthridine analogues as antimycobacterial agents

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 24, 2013, Pages 6805-6810

  Nagesh, Hunsur Nagendra ^a   Naidu, Kalaga Mahalakshmi ^a   Rao, Damarla Harika ^a   Sridevi, Jonnalagadda Padma ^a   Sriram, Dharmarajan ^a   Yogeeswari, Perumal ^a   Chandra Sekhar, Kondapalli Venkata Gowri ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Anti tubercular activity; Click chemistry; Phenanthridine; Piperazine; Triazole

Indexed keywords

ANTIMYCOBACTERIAL AGENT; ISONIAZID; PHENANTHRIDINE DERIVATIVE; RIFAMPICIN;

ANIMAL CELL; ARTICLE; CLICK CHEMISTRY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SELECTIVITY; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

MYCOBACTERIUM TUBERCULOSIS;

ANTI-TUBERCULAR ACTIVITY; CLICK CHEMISTRY; PHENANTHRIDINE; PIPERAZINE; TRIAZOLE;

ANIMALS; ANTITUBERCULAR AGENTS; CELL LINE; CELL SURVIVAL; CLICK CHEMISTRY; DRUG DESIGN; MICE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PHENANTHRIDINES; PIPERAZINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84888859132     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.10.016     Document Type: Article

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