메뉴 건너뛰기




Volumn 7, Issue 11, 2013, Pages 9558-9570

Synergistic targeting of cell membrane, cytoplasm, and nucleus of cancer cells using rod-shaped nanoparticles

Author keywords

camptothecin; doxorubicin; herceptin; morphology; nanoparticle; shape; synergistic

Indexed keywords

CAMPTOTHECIN (CPT); DOXORUBICIN; HERCEPTIN; SHAPE; SYNERGISTIC;

EID: 84888858196     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn403913k     Document Type: Article
Times cited : (98)

References (79)
  • 1
    • 36148987251 scopus 로고    scopus 로고
    • Multifunctional poly(d,l-lactide-co-glycolide)/montmorillonite (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer
    • DOI 10.1016/j.biomaterials.2007.09.038, PII S0142961207007909
    • Sun, B.; Ranganathan, B.; Feng, S.-S. Multifunctional Poly(d, l-lactide-co-glycolide)/Montmorillonite (PLGA/MMT) Nanoparticles Decorated by Trastuzumab for Targeted Chemotherapy of Breast Cancer Biomaterials 2008, 29, 475-486 (Pubitemid 350110345)
    • (2008) Biomaterials , vol.29 , Issue.4 , pp. 475-486
    • Sun, B.1    Ranganathan, B.2    Feng, S.-S.3
  • 2
    • 75749088450 scopus 로고    scopus 로고
    • Mechanism of Active Targeting in Solid Tumors with Transferrin-Containing Gold Nanoparticles
    • Choi, C. H. J.; Alabi, C. A.; Webster, P.; Davis, M. E. Mechanism of Active Targeting in Solid Tumors with Transferrin-Containing Gold Nanoparticles Proc. Natl. Acad. Sci. U. S. A. 2010, 107, 1235-1240
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 1235-1240
    • Choi, C.H.J.1    Alabi, C.A.2    Webster, P.3    Davis, M.E.4
  • 3
    • 84865027076 scopus 로고    scopus 로고
    • Multimodality Treatment of Cancer with Herceptin Conjugated, Thermomagnetic Iron Oxides and Docetaxel Loaded Nanoparticles of Biodegradable Polymers
    • Mi, Y.; Liu, X.; Zhao, J.; Ding, J.; Feng, S. S. Multimodality Treatment of Cancer with Herceptin Conjugated, Thermomagnetic Iron Oxides and Docetaxel Loaded Nanoparticles of Biodegradable Polymers Biomaterials 2012, 33, 7519-7529
    • (2012) Biomaterials , vol.33 , pp. 7519-7529
    • Mi, Y.1    Liu, X.2    Zhao, J.3    Ding, J.4    Feng, S.S.5
  • 5
    • 3543022686 scopus 로고    scopus 로고
    • In vivo cancer targeting and imaging with semiconductor quantum dots
    • DOI 10.1038/nbt994
    • Gao, X.; Cui, Y.; Levenson, R. M.; Chung, L. W. K.; Nie, S. In Vivo Cancer Targeting and Imaging with Semiconductor Quantum Dots Nat. Biotechnol. 2004, 22, 969-976 (Pubitemid 39014473)
    • (2004) Nature Biotechnology , vol.22 , Issue.8 , pp. 969-976
    • Gao, X.1    Cui, Y.2    Levenson, R.M.3    Chung, L.W.K.4    Nie, S.5
  • 6
    • 33745494861 scopus 로고    scopus 로고
    • Camptothecin in sterically stabilized phospholipid micelles: A novel nanomedicine
    • DOI 10.1016/j.nano.2004.11.002, PII S1549963404000036
    • Koo, O. M.; Rubinstein, I.; Onyuksel, H. Camptothecin in Sterically Stabilized Phospholipid Micelles: A Novel Nanomedicine Nanomedicine 2005, 1, 77-84 (Pubitemid 43963604)
    • (2005) Nanomedicine: Nanotechnology, Biology, and Medicine , vol.1 , Issue.1 , pp. 77-84
    • Koo, O.M.1    Rubinstein, I.2    Onyuksel, H.3
  • 7
    • 84866148434 scopus 로고    scopus 로고
    • The Use of a Tumor Metastasis Targeting Peptide to Deliver Doxorubicin-Containing Liposomes to Highly Metastatic Cancer
    • Wang, Z.; Yu, Y.; Dai, W.; Lu, J.; Cui, J.; Wu, H.; Yuan, L.; Zhang, H.; Wang, X.; Wang, J. et al. The Use of a Tumor Metastasis Targeting Peptide To Deliver Doxorubicin-Containing Liposomes to Highly Metastatic Cancer Biomaterials 2012, 33, 8451-8460
    • (2012) Biomaterials , vol.33 , pp. 8451-8460
    • Wang, Z.1    Yu, Y.2    Dai, W.3    Lu, J.4    Cui, J.5    Wu, H.6    Yuan, L.7    Zhang, H.8    Wang, X.9    Wang, J.10
  • 8
    • 68349141561 scopus 로고    scopus 로고
    • Monoclonal Antibody-Functionalized Mesoporous Silica Nanoparticles (MSN) for Selective Targeting Breast Cancer Cells
    • Tsai, C.-P.; Chen, C.-Y.; Hung, Y.; Chang, F.-H.; Mou, C.-Y. Monoclonal Antibody-Functionalized Mesoporous Silica Nanoparticles (MSN) for Selective Targeting Breast Cancer Cells J. Mater. Chem. 2009, 19, 5737-5743
    • (2009) J. Mater. Chem. , vol.19 , pp. 5737-5743
    • Tsai, C.-P.1    Chen, C.-Y.2    Hung, Y.3    Chang, F.-H.4    Mou, C.-Y.5
  • 9
    • 34249894977 scopus 로고    scopus 로고
    • Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody
    • DOI 10.1016/j.jconrel.2007.03.012, PII S0168365907001472
    • Kocbek, P.; Obermajer, N.; Cegnar, M.; Kos, J.; Kristl, J. Targeting Cancer Cells Using PLGA Nanoparticles Surface Modified with Monoclonal Antibody J. Controlled Release 2007, 120, 18-26 (Pubitemid 46874614)
    • (2007) Journal of Controlled Release , vol.120 , Issue.1-2 , pp. 18-26
    • Kocbek, P.1    Obermajer, N.2    Cegnar, M.3    Kos, J.4    Kristl, J.5
  • 11
    • 36248973801 scopus 로고    scopus 로고
    • Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on Bi-fluorescence resonance energy transfer
    • DOI 10.1021/nl071546n
    • Bagalkot, V.; Zhang, L.; Levy-Nissenbaum, E.; Jon, S.; Kantoff, P. W.; Langer, R.; Farokhzad, O. C. Quantum Dot-Aptamer Conjugates for Synchronous Cancer Imaging, Therapy, and Sensing of Drug Delivery Based on Bi-Fluorescence Resonance Energy Transfer Nano Lett. 2007, 7, 3065-3070 (Pubitemid 350132931)
    • (2007) Nano Letters , vol.7 , Issue.10 , pp. 3065-3070
    • Bagalkot, V.1    Zhang, L.2    Levy-Nissenbaum, E.3    Jon, S.4    Kantoff, P.W.5    Langery, R.6    Farokhzad, O.C.7
  • 12
    • 84856153806 scopus 로고    scopus 로고
    • Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection
    • Xiao, Z.; Levy-Nissenbaum, E.; Alexis, F.; Lupták, A.; Teply, B. A.; Chan, J. M.; Shi, J.; Digga, E.; Cheng, J.; Langer, R. et al. Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection ACS Nano 2012, 6, 696-704
    • (2012) ACS Nano , vol.6 , pp. 696-704
    • Xiao, Z.1    Levy-Nissenbaum, E.2    Alexis, F.3    Lupták, A.4    Teply, B.A.5    Chan, J.M.6    Shi, J.7    Digga, E.8    Cheng, J.9    Langer, R.10
  • 17
    • 74349124409 scopus 로고    scopus 로고
    • Endocytosis and Intracellular Distribution of PLGA Particles in Endothelial Cells: Effect of Particle Geometry
    • Yoo, J.-W.; Doshi, N.; Mitragotri, S. Endocytosis and Intracellular Distribution of PLGA Particles in Endothelial Cells: Effect of Particle Geometry Macromol. Rapid Commun. 2010, 31, 142-148
    • (2010) Macromol. Rapid Commun. , vol.31 , pp. 142-148
    • Yoo, J.-W.1    Doshi, N.2    Mitragotri, S.3
  • 19
    • 83655190545 scopus 로고    scopus 로고
    • Receptor-Mediated Endocytosis of Nanoparticles of Various Shapes
    • Vácha, R.; Martinez-Veracoechea, F. J.; Frenkel, D. Receptor-Mediated Endocytosis of Nanoparticles of Various Shapes Nano Lett. 2011, 11, 5391-5395
    • (2011) Nano Lett. , vol.11 , pp. 5391-5395
    • Vácha, R.1    Martinez-Veracoechea, F.J.2    Frenkel, D.3
  • 23
    • 9444279605 scopus 로고    scopus 로고
    • Ligand binding and kinetics of folate receptor recycling in vivo: Impact on receptor-mediated drug delivery
    • DOI 10.1124/mol.104.003723
    • Paulos, C. M.; Reddy, J. A.; Leamon, C. P.; Turk, M. J.; Low, P. S. Ligand Binding and Kinetics of Folate Receptor Recycling in Vivo: Impact on Receptor-Mediated Drug Delivery Mol. Pharmacol. 2004, 66, 1406-1414 (Pubitemid 39564767)
    • (2004) Molecular Pharmacology , vol.66 , Issue.6 , pp. 1406-1414
    • Paulos, C.M.1    Reddy, J.A.2    Leamon, C.P.3    Turk, M.J.4    Low, P.S.5
  • 24
    • 77649121111 scopus 로고    scopus 로고
    • Functional Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Mixed Anticancer Drugs
    • Zhang, L.; Xia, J.; Zhao, Q.; Liu, L.; Zhang, Z. Functional Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Mixed Anticancer Drugs Small 2010, 6, 537-544
    • (2010) Small , vol.6 , pp. 537-544
    • Zhang, L.1    Xia, J.2    Zhao, Q.3    Liu, L.4    Zhang, Z.5
  • 25
    • 4544358907 scopus 로고    scopus 로고
    • Efficacy of transferrin-conjugated paclitaxel-loaded nanoparticles in a murine model of prostate cancer
    • DOI 10.1002/ijc.20405
    • Sahoo, S. K.; Ma, W.; Labhasetwar, V. Efficacy of Transferrin-Conjugated Paclitaxel-Loaded Nanoparticles in a Murine Model of Prostate Cancer Int. J. Cancer 2004, 112, 335-340 (Pubitemid 39244375)
    • (2004) International Journal of Cancer , vol.112 , Issue.2 , pp. 335-340
    • Sahoo, S.K.1    Ma, W.2    Labhasetwar, V.3
  • 26
    • 24144490885 scopus 로고    scopus 로고
    • Enhanced antiproliferative activity of transferrin-conjugated paclitaxel-loaded nanoparticles is mediated via sustained intracellular drug retention
    • DOI 10.1021/mp050032z
    • Sahoo, S. K.; Labhasetwar, V. Enhanced Antiproliferative Activity of Transferrin-Conjugated Paclitaxel-Loaded Nanoparticles Is Mediated via Sustained Intracellular Drug Retention Mol. Pharmaceutics 2005, 2, 373-383 (Pubitemid 41503678)
    • (2005) Molecular Pharmaceutics , vol.2 , Issue.5 , pp. 373-383
    • Sahoo, S.K.1    Labhasetwar, V.2
  • 27
    • 0025719903 scopus 로고
    • Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin
    • Jaxel, C.; Capranico, G.; Kerrigan, D.; Kohn, K. W.; Pommier, Y. Effect of Local DNA Sequence on Topoisomerase I Cleavage in the Presence or Absence of Camptothecin J. Biol. Chem. 1991, 266, 20418-20423 (Pubitemid 21908475)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.30 , pp. 20418-20423
    • Jaxel, C.1    Capranico, G.2    Kerrigan, D.3    Kohn, K.W.4    Pommier, Y.5
  • 28
    • 0024560495 scopus 로고
    • Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: Evidence for a specific receptor site and a relation to antitumor activity
    • Jaxel, C.; Kohn, K. W.; Wani, M. C.; Wall, M. E.; Pommier, Y. Structure-Activity Study of the Actions of Camptothecin Derivatives on Mammalian Topoisomerase I: Evidence for a Specific Receptor Site and a Relation to Antitumor Activity Cancer Res. 1989, 49, 1465-1469 (Pubitemid 19088683)
    • (1989) Cancer Research , vol.49 , Issue.6 , pp. 1465-1469
    • Jaxel, C.1    Kohn, K.W.2    Wani, M.C.3    Wall, M.E.4    Pommier, Y.5
  • 29
    • 17144371295 scopus 로고    scopus 로고
    • Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
    • DOI 10.1021/jm049146p
    • Staker, B. L.; Feese, M. D.; Cushman, M.; Pommier, Y.; Zembower, D.; Stewart, L.; Burgin, A. B. Structures of Three Classes of Anticancer Agents Bound to the Human Topoisomerase I-DNA Covalent Complex J. Med. Chem. 2005, 48, 2336-2345 (Pubitemid 40516428)
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.7 , pp. 2336-2345
    • Staker, B.L.1    Feese, M.D.2    Cushman, M.3    Pommier, Y.4    Zembower, D.5    Stewart, L.6    Burgin, A.B.7
  • 30
    • 79952092706 scopus 로고    scopus 로고
    • Phase II Study of the Antibody Drug Conjugate Trastuzumab-Dm1 for the Treatment of Human Epidermal Growth Factor Receptor 2 (Her2)-Positive Breast Cancer after Prior Her2-Directed Therapy
    • Burris, H. A.; Rugo, H. S.; Vukelja, S. J.; Vogel, C. L.; Borson, R. A.; Limentani, S.; Tan-Chiu, E.; Krop, I. E.; Michaelson, R. A.; Girish, S. et al. Phase II Study of the Antibody Drug Conjugate Trastuzumab-Dm1 for the Treatment of Human Epidermal Growth Factor Receptor 2 (Her2)-Positive Breast Cancer after Prior Her2-Directed Therapy J. Clin. Oncol. 2011, 29, 398-405
    • (2011) J. Clin. Oncol. , vol.29 , pp. 398-405
    • Burris, H.A.1    Rugo, H.S.2    Vukelja, S.J.3    Vogel, C.L.4    Borson, R.A.5    Limentani, S.6    Tan-Chiu, E.7    Krop, I.E.8    Michaelson, R.A.9    Girish, S.10
  • 32
    • 0032850677 scopus 로고    scopus 로고
    • Multinational Study of the Efficacy and Safety of Humanized Anti-Her2 Monoclonal Antibody in Women Who Have Her2-Overexpressing Metastatic Breast Cancer That Has Progressed after Chemotherapy for Metastatic Disease
    • Cobleigh, M. A.; Vogel, C. L.; Tripathy, D.; Robert, N. J.; Scholl, S.; Fehrenbacher, L.; Wolter, J. M.; Paton, V.; Shak, S.; Lieberman, G. et al. Multinational Study of the Efficacy and Safety of Humanized Anti-Her2 Monoclonal Antibody in Women Who Have Her2-Overexpressing Metastatic Breast Cancer That Has Progressed after Chemotherapy for Metastatic Disease J. Clin. Oncol. 1999, 17, 2639
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2639
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3    Robert, N.J.4    Scholl, S.5    Fehrenbacher, L.6    Wolter, J.M.7    Paton, V.8    Shak, S.9    Lieberman, G.10
  • 33
    • 78549272751 scopus 로고    scopus 로고
    • Trastuzumab: In Her2-Positive Metastatic Gastric Cancer
    • Croxtall, J. D.; McKeage, K. Trastuzumab: In Her2-Positive Metastatic Gastric Cancer Drugs 2010, 70, 2259-2267
    • (2010) Drugs , vol.70 , pp. 2259-2267
    • Croxtall, J.D.1    McKeage, K.2
  • 34
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in Combination with Chemotherapy versus Chemotherapy Alone for Treatment of Her2-Positive Advanced Gastric or Gastro-Oesophageal Junction Cancer (Toga): A Phase 3, Open-Label, Randomised Controlled Trial
    • Bang, Y.-J.; Van Cutsem, E.; Feyereislova, A.; Chung, H. C.; Shen, L.; Sawaki, A.; Lordick, F.; Ohtsu, A.; Omuro, Y.; Satoh, T. et al. Trastuzumab in Combination with Chemotherapy versus Chemotherapy Alone for Treatment of Her2-Positive Advanced Gastric or Gastro-Oesophageal Junction Cancer (Toga): A Phase 3, Open-Label, Randomised Controlled Trial Lancet 2010, 376, 687-697
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.-J.1    Van Cutsem, E.2    Feyereislova, A.3    Chung, H.C.4    Shen, L.5    Sawaki, A.6    Lordick, F.7    Ohtsu, A.8    Omuro, Y.9    Satoh, T.10
  • 36
    • 18744395754 scopus 로고    scopus 로고
    • Preoperative Therapy with Trastuzumab and Paclitaxel Followed by Sequential Adjuvant Doxorubicin/Cyclophosphamide for Her2 Overexpressing Stage II or III Breast Cancer: A Pilot Study
    • Burstein, H. J.; Harris, L. N.; Gelman, R.; Lester, S. C.; Nunes, R. A.; Kaelin, C. M.; Parker, L. M.; Ellisen, L. W.; Kuter, I.; Gadd, M. A. et al. Preoperative Therapy with Trastuzumab and Paclitaxel Followed by Sequential Adjuvant Doxorubicin/Cyclophosphamide for Her2 Overexpressing Stage II or III Breast Cancer: A Pilot Study J. Clin. Oncol. 2003, 21, 46-53
    • (2003) J. Clin. Oncol. , vol.21 , pp. 46-53
    • Burstein, H.J.1    Harris, L.N.2    Gelman, R.3    Lester, S.C.4    Nunes, R.A.5    Kaelin, C.M.6    Parker, L.M.7    Ellisen, L.W.8    Kuter, I.9    Gadd, M.A.10
  • 38
    • 34249342246 scopus 로고    scopus 로고
    • Her-2-Positive Metastatic Breast Cancer: Optimizing Trastuzumab-Based Therapy
    • Jackisch, C. Her-2-Positive Metastatic Breast Cancer: Optimizing Trastuzumab-Based Therapy Oncologist 2006, 11, 34-41
    • (2006) Oncologist , vol.11 , pp. 34-41
    • Jackisch, C.1
  • 42
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologie developments in antitumor activity and cardiotoxicity
    • DOI 10.1124/pr.56.2.6
    • Minotti, G.; Menna, P.; Salvatorelli, E.; Cairo, G.; Gianni, L. Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity Pharmacol. Rev. 2004, 56, 185-229 (Pubitemid 38720829)
    • (2004) Pharmacological Reviews , vol.56 , Issue.2 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 47
    • 0021118703 scopus 로고
    • Quantitative Analysis of Dose-Effect Relationships: The Combined Effects of Multiple Drugs or Enzyme Inhibitors
    • Chou, T.-C.; Talalay, P. Quantitative Analysis of Dose-Effect Relationships: The Combined Effects of Multiple Drugs or Enzyme Inhibitors Adv. Enzyme Regul. 1984, 22, 27-55
    • (1984) Adv. Enzyme Regul. , vol.22 , pp. 27-55
    • Chou, T.-C.1    Talalay, P.2
  • 48
    • 56949108012 scopus 로고    scopus 로고
    • Her2-Positive Breast Cancer: Herceptin and beyond
    • Dean-Colomb, W.; Esteva, F. J. Her2-Positive Breast Cancer: Herceptin and Beyond Eur. J. Cancer 2008, 44, 2806-2812
    • (2008) Eur. J. Cancer , vol.44 , pp. 2806-2812
    • Dean-Colomb, W.1    Esteva, F.J.2
  • 49
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • Hsiang, Y.-H.; Lihou, M. G.; Liu, L. F. Arrest of Replication Forks by Drug-Stabilized Topoisomerase I-DNA Cleavable Complexes as a Mechanism of Cell Killing by Camptothecin Cancer Res. 1989, 49, 5077-5082 (Pubitemid 19239347)
    • (1989) Cancer Research , vol.49 , Issue.18 , pp. 5077-5082
    • Hsiang, Y.-H.1    Lihou, M.G.2    Liu, L.F.3
  • 50
    • 0029892120 scopus 로고    scopus 로고
    • Cell Cycle-Dependent Cytotoxicity, G2/M Phase Arrest, and Disruption of P34cdc2/Cyclin B1 Activity Induced by Doxorubicin in Synchronized P388 Cells
    • Ling, Y. H.; el-Naggar, A. K.; Priebe, W.; Perez-Soler, R. Cell Cycle-Dependent Cytotoxicity, G2/M Phase Arrest, and Disruption of P34cdc2/Cyclin B1 Activity Induced by Doxorubicin in Synchronized P388 Cells Mol. Pharmacol. 1996, 49, 832-841
    • (1996) Mol. Pharmacol. , vol.49 , pp. 832-841
    • Ling, Y.H.1    El-Naggar, A.K.2    Priebe, W.3    Perez-Soler, R.4
  • 51
    • 73849138217 scopus 로고    scopus 로고
    • Quantitative Investigation of Compartmentalized Dynamics of Erbb2 Targeting Gold Nanorods in Live Cells by Single Molecule Spectroscopy
    • Chen, J.; Irudayaraj, J. Quantitative Investigation of Compartmentalized Dynamics of Erbb2 Targeting Gold Nanorods in Live Cells by Single Molecule Spectroscopy ACS Nano 2009, 3, 4071-4079
    • (2009) ACS Nano , vol.3 , pp. 4071-4079
    • Chen, J.1    Irudayaraj, J.2
  • 53
    • 60549097550 scopus 로고    scopus 로고
    • Multivalent Scaffolds for Affinity Maturation of Small Molecule Cell Surface Binders and Their Application to Prostate Tumor Targeting
    • Humblet, V.; Misra, P.; Bhushan, K. R.; Nasr, K.; Ko, Y.-S.; Tsukamoto, T.; Pannier, N.; Frangioni, J. V.; Maison, W. Multivalent Scaffolds for Affinity Maturation of Small Molecule Cell Surface Binders and Their Application to Prostate Tumor Targeting J. Med. Chem. 2009, 52, 544-550
    • (2009) J. Med. Chem. , vol.52 , pp. 544-550
    • Humblet, V.1    Misra, P.2    Bhushan, K.R.3    Nasr, K.4    Ko, Y.-S.5    Tsukamoto, T.6    Pannier, N.7    Frangioni, J.V.8    Maison, W.9
  • 54
    • 33746092084 scopus 로고    scopus 로고
    • The adhesive strength of non-spherical particles mediated by specific interactions
    • DOI 10.1016/j.biomaterials.2006.05.024, PII S0142961206004662
    • Decuzzi, P.; Ferrari, M. The Adhesive Strength of Non-spherical Particles Mediated by Specific Interactions Biomaterials 2006, 27, 5307-5314 (Pubitemid 44080296)
    • (2006) Biomaterials , vol.27 , Issue.30 , pp. 5307-5314
    • Decuzzi, P.1    Ferrari, M.2
  • 55
    • 43849112187 scopus 로고    scopus 로고
    • The Receptor-Mediated Endocytosis of Nonspherical Particles
    • Decuzzi, P.; Ferrari, M. The Receptor-Mediated Endocytosis of Nonspherical Particles Biophys. J. 2008, 94, 3790-3797
    • (2008) Biophys. J. , vol.94 , pp. 3790-3797
    • Decuzzi, P.1    Ferrari, M.2
  • 56
    • 48349116380 scopus 로고    scopus 로고
    • Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of Icam-1-Targeted Carriers
    • Muro, S.; Garnacho, C.; Champion, J. A.; Leferovich, J.; Gajewski, C.; Schuchman, E. H.; Mitragotri, S.; Muzykantov, V. R. Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of Icam-1-Targeted Carriers Mol. Ther. 2008, 16, 1450-1458
    • (2008) Mol. Ther. , vol.16 , pp. 1450-1458
    • Muro, S.1    Garnacho, C.2    Champion, J.A.3    Leferovich, J.4    Gajewski, C.5    Schuchman, E.H.6    Mitragotri, S.7    Muzykantov, V.R.8
  • 57
    • 61849104968 scopus 로고    scopus 로고
    • Size-Dependent Cellular Uptake and Expulsion of Single-Walled Carbon Nanotubes: Single Particle Tracking and a Generic Uptake Model for Nanoparticles
    • Jin, H.; Heller, D. A.; Sharma, R.; Strano, M. S. Size-Dependent Cellular Uptake and Expulsion of Single-Walled Carbon Nanotubes: Single Particle Tracking and a Generic Uptake Model for Nanoparticles ACS Nano 2009, 3, 149-158
    • (2009) ACS Nano , vol.3 , pp. 149-158
    • Jin, H.1    Heller, D.A.2    Sharma, R.3    Strano, M.S.4
  • 59
    • 70449088926 scopus 로고    scopus 로고
    • The Effect of the Shape of Mesoporous Silica Nanoparticles on Cellular Uptake and Cell Function
    • Huang, X.; Teng, X.; Chen, D.; Tang, F.; He, J. The Effect of the Shape of Mesoporous Silica Nanoparticles on Cellular Uptake and Cell Function Biomaterials 2010, 31, 438-448
    • (2010) Biomaterials , vol.31 , pp. 438-448
    • Huang, X.1    Teng, X.2    Chen, D.3    Tang, F.4    He, J.5
  • 60
    • 84866506234 scopus 로고    scopus 로고
    • Polymer Microparticles Exhibit Size and Shape Dependent Accumulation around the Nucleus after Endocytosis
    • Kolhar, P.; Mitragotri, S. Polymer Microparticles Exhibit Size and Shape Dependent Accumulation around the Nucleus after Endocytosis Adv. Funct. Mater. 2012, 22, 3759-3764
    • (2012) Adv. Funct. Mater. , vol.22 , pp. 3759-3764
    • Kolhar, P.1    Mitragotri, S.2
  • 62
    • 1542330612 scopus 로고    scopus 로고
    • Subcellular localization of the camptothecin analogues, topotecan and gimatecan
    • DOI 10.1016/j.bcp.2003.10.034, PII S0006295203008906
    • Croce, A. C.; Bottiroli, G.; Supino, R.; Favini, E.; Zuco, V.; Zunino, F. Subcellular Localization of the Camptothecin Analogues, Topotecan and Gimatecan Biochem. Pharmacol. 2004, 67, 1035-1045 (Pubitemid 38296783)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.6 , pp. 1035-1045
    • Croce, A.C.1    Bottiroli, G.2    Supino, R.3    Favini, E.4    Zuco, V.5    Zunino, F.6
  • 63
    • 14544272335 scopus 로고    scopus 로고
    • Regulation of nuclear transport: Central role in development and transformation?
    • DOI 10.1111/j.1600-0854.2005.00268.x
    • Poon, I. K. H.; Jans, D. A. Regulation of Nuclear Transport: Central Role in Development and Transformation? Traffic 2005, 6, 173-186 (Pubitemid 40298152)
    • (2005) Traffic , vol.6 , Issue.3 , pp. 173-186
    • Poon, I.K.H.1    Jans, D.A.2
  • 64
    • 74149089955 scopus 로고    scopus 로고
    • Intracellular Trafficking of Nuclear Localization Signal Conjugated Nanoparticles for Cancer Therapy
    • Misra, R.; Sahoo, S. K. Intracellular Trafficking of Nuclear Localization Signal Conjugated Nanoparticles for Cancer Therapy Eur. J. Pharm. Sci. 2010, 39, 152-163
    • (2010) Eur. J. Pharm. Sci. , vol.39 , pp. 152-163
    • Misra, R.1    Sahoo, S.K.2
  • 65
    • 84870341677 scopus 로고    scopus 로고
    • Fabrication and Characterization of Nuclear Localization Signal-Conjugated Glycol Chitosan Micelles for Improving the Nuclear Delivery of Doxorubicin
    • Yu, J.; Xie, X.; Zheng, M.; Yu, L.; Zhang, L.; Zhao, J.; Jiang, D.; Che, X. Fabrication and Characterization of Nuclear Localization Signal-Conjugated Glycol Chitosan Micelles for Improving the Nuclear Delivery of Doxorubicin Int. J. Nanomed. 2012, 7, 5079-5090
    • (2012) Int. J. Nanomed. , vol.7 , pp. 5079-5090
    • Yu, J.1    Xie, X.2    Zheng, M.3    Yu, L.4    Zhang, L.5    Zhao, J.6    Jiang, D.7    Che, X.8
  • 66
    • 15244345124 scopus 로고    scopus 로고
    • PH-responsive copolymer assemblies for controlled release of doxorubicin
    • DOI 10.1021/bc049851c
    • Gillies, E. R.; Fréchet, J. M. J. pH-Responsive Copolymer Assemblies for Controlled Release of Doxorubicin Bioconjugate Chem. 2005, 16, 361-368 (Pubitemid 40388212)
    • (2005) Bioconjugate Chemistry , vol.16 , Issue.2 , pp. 361-368
    • Gillies, E.R.1    Frechet, J.M.J.2
  • 67
    • 84884213664 scopus 로고    scopus 로고
    • Comparative Studies of Polyethylenimine-Doxorubicin Conjugates with pH-Sensitive and pH-Insensitive Linkers
    • Dong, D.-W.; Tong, S.-W.; Qi, X.-R. Comparative Studies of Polyethylenimine-Doxorubicin Conjugates with pH-Sensitive and pH-Insensitive Linkers J. Biomed. Mater. Res., Part A 2013, 101A, 1336-1344
    • (2013) J. Biomed. Mater. Res., Part A , vol.101 , pp. 1336-1344
    • Dong, D.-W.1    Tong, S.-W.2    Qi, X.-R.3
  • 68
    • 0019990630 scopus 로고
    • Molecular association between doxorubicin (adriamycin) and DNA-derived bases, nucleosides, nucleotides, other aromatic compounds, and proteins in aqueous solution
    • Dalmark, M.; Johansen, P. Molecular Association between Doxorubicin (Adriamycin) and DNA-Derived Bases, Nucleosides, Nucleotides, Other Aromatic Compounds, and Proteins in Aqueous Solution Mol. Pharmacol. 1982, 22, 158-165 (Pubitemid 12097277)
    • (1982) Molecular Pharmacology , vol.22 , Issue.1 , pp. 158-165
    • Dalmark, M.1    Johansen, P.2
  • 69
    • 78649934894 scopus 로고    scopus 로고
    • Doxorubicin as a Molecular Nanotheranostic Agent: Effect of Doxorubicin Encapsulation in Micelles or Nanoemulsions on the Ultrasound-Mediated Intracellular Delivery and Nuclear Trafficking
    • Mohan, P.; Rapoport, N. Doxorubicin as a Molecular Nanotheranostic Agent: Effect of Doxorubicin Encapsulation in Micelles or Nanoemulsions on the Ultrasound-Mediated Intracellular Delivery and Nuclear Trafficking Mol. Pharmaceutics 2010, 7, 1959-1973
    • (2010) Mol. Pharmaceutics , vol.7 , pp. 1959-1973
    • Mohan, P.1    Rapoport, N.2
  • 70
    • 0019985743 scopus 로고
    • Pharmacokinetics of adriamycin in patients with breast cancer: Correlation between clinical short-term response
    • DOI 10.1016/0277-5379(82)90072-4
    • Robert, J.; Illiadis, A.; Hoerni, B.; Cano, J.-P.; Durand, M.; Lagarde, C. Pharmacokinetics of Adriamycin in Patients with Breast Cancer: Correlation between Pharmacokinetic Parameters and Clinical Short-Term Response Eur. J. Cancer Clin. Oncol. 1982, 18, 739-745 (Pubitemid 12033227)
    • (1982) European Journal of Cancer and Clinical Oncology , vol.18 , Issue.8 , pp. 739-745
    • Robert, J.1    Illiadis, A.2    Hoerni, B.3
  • 71
    • 0036201885 scopus 로고    scopus 로고
    • Flow cytometric analysis of the cell cycle phase specificity of DNA damage induced by radiation, hydrogen peroxide and doxorubicin
    • Potter, A. J.; Gollahon, K. A.; Palanca, B. J. A.; Harbert, M. J.; Choi, Y. M.; Moskovitz, A. H.; Potter, J. D.; Rabinovitch, P. S. Flow Cytometric Analysis of the Cell Cycle Phase Specificity of DNA Damage Induced by Radiation, Hydrogen Peroxide and Doxorubicin Carcinogenesis 2002, 23, 389-401 (Pubitemid 34257618)
    • (2002) Carcinogenesis , vol.23 , Issue.3 , pp. 389-401
    • Potter, A.J.1    Gollahon, K.A.2    Palanca, B.J.A.3    Harbert, M.J.4    Choi, Y.M.5    Moskovitz, A.H.6    Potter, J.D.7    Rabinovitch, P.S.8
  • 72
    • 7144248725 scopus 로고
    • Plant Antitumor Agents. I. the Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca Acuminata1,2
    • Wall, M. E.; Wani, M. C.; Cook, C. E.; Palmer, K. H.; McPhail, A. T.; Sim, G. A. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca Acuminata1,2 J. Am. Chem. Soc. 1966, 88, 3888-3890
    • (1966) J. Am. Chem. Soc. , vol.88 , pp. 3888-3890
    • Wall, M.E.1    Wani, M.C.2    Cook, C.E.3    Palmer, K.H.4    McPhail, A.T.5    Sim, G.A.6
  • 74
    • 26444500499 scopus 로고    scopus 로고
    • Determination of doxorubicin levels in whole tumor and tumor nuclei in murine breast cancer tumors
    • DOI 10.1158/1078-0432.CCR-05-0343
    • Laginha, K. M.; Verwoert, S.; Charrois, G. J. R.; Allen, T. M. Determination of Doxorubicin Levels in Whole Tumor and Tumor Nuclei in Murine Breast Cancer Tumors Clin. Cancer Res. 2005, 11, 6944-6949 (Pubitemid 41428752)
    • (2005) Clinical Cancer Research , vol.11 , Issue.19 , pp. 6944-6949
    • Laginha, K.M.1    Verwoert, S.2    Charrois, G.J.R.3    Allen, T.M.4
  • 75
    • 39649115201 scopus 로고    scopus 로고
    • Particle Size-Dependent Organ Distribution of Gold Nanoparticles after Intravenous Administration
    • De Jong, W. H.; Hagens, W. I.; Krystek, P.; Burger, M. C.; Sips, A. J. A. M.; Geertsma, R. E. Particle Size-Dependent Organ Distribution of Gold Nanoparticles after Intravenous Administration Biomaterials 2008, 29, 1912-1919
    • (2008) Biomaterials , vol.29 , pp. 1912-1919
    • De Jong, W.H.1    Hagens, W.I.2    Krystek, P.3    Burger, M.C.4    Sips, A.J.A.M.5    Geertsma, R.E.6
  • 76
    • 70149110440 scopus 로고    scopus 로고
    • Evaluation of the Tolerance and Distribution of Intravenously Applied Ferrofluid Particles of 250 and 500 nm Size in an Animal Model
    • Wiegand, S.; Heinen, T.; Ramaswamy, A.; Sesterhenn, A. M.; Bergemann, C.; Werner, J. A.; Lübbe, A. S. Evaluation of the Tolerance and Distribution of Intravenously Applied Ferrofluid Particles of 250 and 500 nm Size in an Animal Model J. Drug Targeting 2009, 17, 194-199
    • (2009) J. Drug Targeting , vol.17 , pp. 194-199
    • Wiegand, S.1    Heinen, T.2    Ramaswamy, A.3    Sesterhenn, A.M.4    Bergemann, C.5    Werner, J.A.6    Lübbe, A.S.7
  • 77
    • 24044459756 scopus 로고    scopus 로고
    • Self-assembled nanoparticles based on glycol chitosan bearing hydrophobic moieties as carriers for doxorubicin: In vivo biodistribution and anti-tumor activity
    • DOI 10.1016/j.biomaterials.2005.05.028, PII S0142961205004229
    • Hyung Park, J.; Kwon, S.; Lee, M.; Chung, H.; Kim, J.-H.; Kim, Y.-S.; Park, R.-W.; Kim, I.-S.; Bong Seo, S.; Kwon, I. C. et al. Self-Assembled Nanoparticles Based on Glycol Chitosan Bearing Hydrophobic Moieties as Carriers for Doxorubicin: In Vivo Biodistribution and Anti-tumor Activity Biomaterials 2006, 27, 119-126 (Pubitemid 41225375)
    • (2006) Biomaterials , vol.27 , Issue.1 , pp. 119-126
    • Jae, H.P.1    Kwon, S.2    Lee, M.3    Chung, H.4    Kim, J.-H.5    Kim, Y.-S.6    Park, R.-W.7    Kim, I.-S.8    Sang, B.S.9    Kwon, I.C.10    Seo, Y.J.11
  • 78
    • 0029150245 scopus 로고
    • Vascular Permeability in a Human Tumor Xenograft: Molecular Size Dependence and Cutoff Size
    • Yuan, F.; Dellian, M.; Fukumura, D.; Leunig, M.; Berk, D. A.; Torchilin, V. P.; Jain, R. K. Vascular Permeability in a Human Tumor Xenograft: Molecular Size Dependence and Cutoff Size Cancer Res. 1995, 55, 3752-3756
    • (1995) Cancer Res. , vol.55 , pp. 3752-3756
    • Yuan, F.1    Dellian, M.2    Fukumura, D.3    Leunig, M.4    Berk, D.A.5    Torchilin, V.P.6    Jain, R.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.