Redox-sensitive structural change in the A-domain of HMGB1 and its implication for the binding to cisplatin modified DNA

Biochemical and Biophysical Research Communications

Volumn 441, Issue 4, 2013, Pages 701-706

  Wang, Jing ^a   Tochio, Naoya ^a   Takeuchi, Aya ^a   Uewaki, Jun ichi ^a   Kobayashi, Naohiro ^b   Tate, Shin ichi ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Cisplatinated DNA; High mobility group B1; NMR structure; Protein oxidation

Indexed keywords

CISPLATINATED DNA; CYSTEINE; DNA; HIGH MOBILITY GROUP B1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; DNA MODIFICATION; DNA PROTEIN COMPLEX; HETERONUCLEAR NUCLEAR MAGNETIC RESONANCE; HUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; CISPLATIN; CYSTEINE; DNA; HMGB1 PROTEIN; HUMANS; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84888843964     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.10.085     Document Type: Article

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