Insufficient ER-stress response causes selective mouse cerebellar granule cell degeneration resembling that seen in congenital disorders of glycosylation

Molecular Brain

Volumn 6, Issue 1, 2013, Pages

  Sun, Liangwu ^a   Zhao, Yingjun ^a,b   Zhou, Kun ^a   Freeze, Hudson H ^a   Zhang, Yun Wu ^a,b   Xu, Huaxi ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b XIAMEN UNIVERSITY   (China)

Author keywords

Cerebellar granule cells; Congenital disorders of glycosylation; Cortical neurons; Endoplasmic reticulum stress; GRP78 BiP; Neurodegeneration; Phosphomannomutase 2

Indexed keywords

ASPARAGINE LINKED OLIGOSACCHARIDE; CASPASE 3; CHAPERONIN 60; GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN 70; PHOSPHOMANNOMUTASE; PHOSPHOMANNOMUTASE 2; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN CELL; CONGENITAL DISORDER OF GLYCOSYLATION; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GLYCOSYLATION; GRANULE CELL; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PURKINJE CELL; UPREGULATION;

ANIMALS; CELL DEATH; CEREBELLUM; CEREBRAL CORTEX; CONGENITAL DISORDERS OF GLYCOSYLATION; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; GLYCOSYLATION; HEAT-SHOCK PROTEINS; MICE; MICE, INBRED C57BL; NERVE DEGENERATION; NEURONS; PHOSPHOTRANSFERASES (PHOSPHOMUTASES); TUNICAMYCIN;

EID: 84888795324     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-6-52     Document Type: Article

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