메뉴 건너뛰기




Volumn 15, Issue 1, 2005, Pages 41-45

The potential of aptamers as anticoagulants

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; APTAMER; ARC 183; ARGATROBAN; BLOOD CLOTTING FACTOR 10A INHIBITOR; BLOOD CLOTTING FACTOR 9A; BLOOD CLOTTING FACTOR IXA INHIBITOR; ENOXAPARIN; HEPARIN; HIRULOG; LEPIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; MONOCLONAL ANTIBODY; PEGAPTANIB; PROTAMINE; PROTEIN INHIBITOR; RECOMBINANT HIRUDIN; REG 1; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 15744384868     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcm.2005.01.002     Document Type: Review
Times cited : (95)

References (28)
  • 1
    • 0026575221 scopus 로고
    • Selection of single-stranded DNA molecules that bind and inhibit human thrombin
    • L.C. Bock, L.C. Griffin, J.A. Latham, E.H. Vermaas, and J.J Toole Selection of single-stranded DNA molecules that bind and inhibit human thrombin Nature 355 1992 564 566
    • (1992) Nature , vol.355 , pp. 564-566
    • Bock, L.C.1    Griffin, L.C.2    Latham, J.A.3    Vermaas, E.H.4    Toole, J.J.5
  • 2
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • S.R. Coughlin Thrombin signalling and protease-activated receptors Nature 407 2000 258 264
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 3
    • 0027956461 scopus 로고
    • Pilot study of the efficacy of a thrombin inhibitor for use during cardiopulmonary bypass
    • A. DeAnda Jr., S.E. Coutre, and M.R. Moon Pilot study of the efficacy of a thrombin inhibitor for use during cardiopulmonary bypass Ann Thor Surg 58 1994 344 350
    • (1994) Ann Thor Surg , vol.58 , pp. 344-350
    • DeAnda Jr., A.1    Coutre, S.E.2    Moon, M.R.3
  • 4
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • A.D. Ellington, and J.W. Szostak In vitro selection of RNA molecules that bind specific ligands Nature 346 1990 818 822
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 5
    • 0036959644 scopus 로고    scopus 로고
    • Preclinical and Phase 1A clinical evaluation of an anti-VEGF pegylated aptamer (EYE001) for the treatment of exudative age-related macular degeneration
    • Eyetech Study Group
    • Eyetech Study Group Preclinical and Phase 1A clinical evaluation of an anti-VEGF pegylated aptamer (EYE001) for the treatment of exudative age-related macular degeneration Retina 22 2002 143 152
    • (2002) Retina , vol.22 , pp. 143-152
  • 6
    • 0037880734 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor therapy for subfoveal choroidal neovascularization secondary to age-related macular degeneration: Phase II study results
    • Eyetech Study Group
    • Eyetech Study Group Anti-vascular endothelial growth factor therapy for subfoveal choroidal neovascularization secondary to age-related macular degeneration: phase II study results [comment] Ophthalmology 110 2003 979 986
    • (2003) Ophthalmology , vol.110 , pp. 979-986
  • 10
    • 0029938993 scopus 로고    scopus 로고
    • Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infarction: Results from the GUSTO-I trial
    • C.B. Granger, J. Hirsch, and R.M. Califf Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infarction: results from the GUSTO-I trial Circulation 93 1996 870 878
    • (1996) Circulation , vol.93 , pp. 870-878
    • Granger, C.B.1    Hirsch, J.2    Califf, R.M.3
  • 11
    • 0027163099 scopus 로고
    • In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits
    • L.C. Griffin, G.F. Tidmarsh, L.C. Bock, J.J. Toole, and L.L. Leung In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits Blood 81 1993 3271 3276
    • (1993) Blood , vol.81 , pp. 3271-3276
    • Griffin, L.C.1    Tidmarsh, G.F.2    Bock, L.C.3    Toole, J.J.4    Leung, L.L.5
  • 12
    • 15744367522 scopus 로고    scopus 로고
    • Developing drugs to prevent and treat arterial thrombosis
    • R.A. Harrington Developing drugs to prevent and treat arterial thrombosis Cardiol Rounds 7 2003 7
    • (2003) Cardiol Rounds , vol.7 , pp. 7
    • Harrington, R.A.1
  • 13
    • 4644327859 scopus 로고    scopus 로고
    • Antithrombotic therapy for coronary artery disease: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • R.A. Harrington, R.C. Becker, and M. Ezekowitz Antithrombotic therapy for coronary artery disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Chest 126 Suppl. 3 2004 513S 548S
    • (2004) Chest , vol.126 , Issue.3 SUPPL.
    • Harrington, R.A.1    Becker, R.C.2    Ezekowitz, M.3
  • 14
    • 0035912864 scopus 로고    scopus 로고
    • Guide to anticoagulant therapy: Heparin: A statement for healthcare professionals from the American Heart Association
    • J. Hirsh, S.S. Anand, and J.L. Halperin Guide to anticoagulant therapy: heparin: a statement for healthcare professionals from the American Heart Association Circulation 103 2001 2994 3018
    • (2001) Circulation , vol.103 , pp. 2994-3018
    • Hirsh, J.1    Anand, S.S.2    Halperin, J.L.3
  • 15
    • 0029114788 scopus 로고
    • Potent 2′-amino-2′-deoxypyrimidine RNA inhibitors of basic fibroblast growth factor
    • D. Jellinek, L.S. Green, and C. Bell Potent 2′-amino-2′- deoxypyrimidine RNA inhibitors of basic fibroblast growth factor Biochemistry 34 1995 11,363 11,372
    • (1995) Biochemistry , vol.34 , pp. 11
    • Jellinek, D.1    Green, L.S.2    Bell, C.3
  • 16
    • 0037167687 scopus 로고    scopus 로고
    • Preoperative use of enoxaparin compared with unfractionated heparin increases the incidence of re-exploration for postoperative bleeding after open-heart surgery in patients who present with an acute coronary syndrome: Clinical investigation and reports
    • H.U. Jones, J.B. Muhlestein, and K.W. Jones Preoperative use of enoxaparin compared with unfractionated heparin increases the incidence of re-exploration for postoperative bleeding after open-heart surgery in patients who present with an acute coronary syndrome: clinical investigation and reports Circulation 106 Suppl. 1 2002 I19 I22
    • (2002) Circulation , vol.106 , Issue.1 SUPPL.
    • Jones, H.U.1    Muhlestein, J.B.2    Jones, K.W.3
  • 17
    • 0037453968 scopus 로고    scopus 로고
    • Bivalirudin and provisional glycoprotein IIb/IIIa blockade compared with heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial
    • A.M. Lincoff, J.A. Bittl, and R.A. Harrington Bivalirudin and provisional glycoprotein IIb/IIIa blockade compared with heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial [see comment] [published erratum appears in JAMA 289:1638 (2003)] JAMA 289 2003 853 863
    • (2003) JAMA , vol.289 , pp. 853-863
    • Lincoff, A.M.1    Bittl, J.A.2    Harrington, R.A.3
  • 18
    • 0035992701 scopus 로고    scopus 로고
    • Overview of anticoagulant drugs for the future
    • S. Moll, and H.R. Roberts Overview of anticoagulant drugs for the future Semin Hematol 39 2002 145 157
    • (2002) Semin Hematol , vol.39 , pp. 145-157
    • Moll, S.1    Roberts, H.R.2
  • 19
    • 4644295940 scopus 로고    scopus 로고
    • Antithrombotic therapy during percutaneous coronary intervention: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • J.J. Popma, P. Berger, and E.M. Ohman Antithrombotic therapy during percutaneous coronary intervention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Chest 126 Suppl. 3 2004 576S 599S
    • (2004) Chest , vol.126 , Issue.3 SUPPL.
    • Popma, J.J.1    Berger, P.2    Ohman, E.M.3
  • 20
    • 4644350897 scopus 로고    scopus 로고
    • Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes
    • S.V. Rao, J.G. Jollis, and R.A. Harrington Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes [see comment] JAMA 292 2004 1555 1562
    • (2004) JAMA , vol.292 , pp. 1555-1562
    • Rao, S.V.1    Jollis, J.G.2    Harrington, R.A.3
  • 21
    • 0032493654 scopus 로고    scopus 로고
    • 2′-fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
    • J. Ruckman, L.S. Green, and J. Beeson 2′-fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain J Biol Chem 273 1998 20,556 20,567
    • (1998) J Biol Chem , vol.273 , pp. 20
    • Ruckman, J.1    Green, L.S.2    Beeson, J.3
  • 22
    • 0033694243 scopus 로고    scopus 로고
    • Blocking the initiation of coagulation by RNA aptamers to factor VIIa
    • C.P. Rusconi, A. Yeh, and H.K. Lyerly Blocking the initiation of coagulation by RNA aptamers to factor VIIa Thromb Haemost 84 2000 841 848
    • (2000) Thromb Haemost , vol.84 , pp. 841-848
    • Rusconi, C.P.1    Yeh, A.2    Lyerly, H.K.3
  • 23
    • 0037026484 scopus 로고    scopus 로고
    • RNA aptamers as reversible antagonists of coagulation factor IXa
    • C.P. Rusconi, E. Scardino, and J. Layzer RNA aptamers as reversible antagonists of coagulation factor IXa [see comment] Nature 419 2002 90 94
    • (2002) Nature , vol.419 , pp. 90-94
    • Rusconi, C.P.1    Scardino, E.2    Layzer, J.3
  • 24
    • 8344221992 scopus 로고    scopus 로고
    • Antidote-mediated control of an anticoagulant aptamer in vivo
    • C.P. Rusconi, J.D. Roberts, and G.A. Pitoc Antidote-mediated control of an anticoagulant aptamer in vivo Nat Biotechnol 22 2004 1423 1428
    • (2004) Nat Biotechnol , vol.22 , pp. 1423-1428
    • Rusconi, C.P.1    Roberts, J.D.2    Pitoc, G.A.3
  • 25
    • 0037241152 scopus 로고    scopus 로고
    • Structure-function relationships in Factor IX and Factor IXa
    • A.E. Schmidt, and S.P. Bajaj Structure-function relationships in Factor IX and Factor IXa Trends Cardiovasc Med 13 2003 39 45
    • (2003) Trends Cardiovasc Med , vol.13 , pp. 39-45
    • Schmidt, A.E.1    Bajaj, S.P.2
  • 26
    • 0032876515 scopus 로고    scopus 로고
    • Detection and plasma pharmacokinetics of an anti-vascular endothelial growth factor oligonucleotide-aptamer (NX1838) in rhesus monkeys
    • C.E. Tucker, L.S. Chen, and M.B. Judkins Detection and plasma pharmacokinetics of an anti-vascular endothelial growth factor oligonucleotide-aptamer (NX1838) in rhesus monkeys Chromatogr B Biomed Sci Appl 732 1999 203 212
    • (1999) Chromatogr B Biomed Sci Appl , vol.732 , pp. 203-212
    • Tucker, C.E.1    Chen, L.S.2    Judkins, M.B.3
  • 27
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • C. Tuerk, and L. Gold Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase Science 249 1990 505 510
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 28
    • 4644242157 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Recognition, treatment, and prevention: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • T.E. Warkentin, and A. Greinacher Heparin-induced thrombocytopenia: recognition, treatment, and prevention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Chest 126 Suppl. 3 2004 311S 337S
    • (2004) Chest , vol.126 , Issue.3 SUPPL.
    • Warkentin, T.E.1    Greinacher, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.