-
1
-
-
70349705617
-
The inability to disrupt the immunological synapse between infected human Tcells and APCs distinguishes HIV-1 from most other primate lentiviruses
-
Arhel N., Lehmann M., Clauss K., Nienhaus G.U., Piguet V., Kirchhoff F. The inability to disrupt the immunological synapse between infected human Tcells and APCs distinguishes HIV-1 from most other primate lentiviruses. J.Clin. Invest. 2009, 119:2965-2975.
-
(2009)
J.Clin. Invest.
, vol.119
, pp. 2965-2975
-
-
Arhel, N.1
Lehmann, M.2
Clauss, K.3
Nienhaus, G.U.4
Piguet, V.5
Kirchhoff, F.6
-
2
-
-
77949591605
-
A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells
-
Banning C., Votteler J., Hoffmann D., Koppensteiner H., Warmer M., Reimer R., Kirchhoff F., Schubert U., Hauber J., Schindler M. A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells. PLoS ONE 2010, 5:e9344.
-
(2010)
PLoS ONE
, vol.5
-
-
Banning, C.1
Votteler, J.2
Hoffmann, D.3
Koppensteiner, H.4
Warmer, M.5
Reimer, R.6
Kirchhoff, F.7
Schubert, U.8
Hauber, J.9
Schindler, M.10
-
3
-
-
72849132344
-
Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys
-
Bosinger S.E., Li Q., Gordon S.N., Klatt N.R., Duan L., Xu L., Francella N., Sidahmed A., Smith A.J., Cramer E.M., et al. Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. J.Clin. Invest. 2009, 119:3556-3572.
-
(2009)
J.Clin. Invest.
, vol.119
, pp. 3556-3572
-
-
Bosinger, S.E.1
Li, Q.2
Gordon, S.N.3
Klatt, N.R.4
Duan, L.5
Xu, L.6
Francella, N.7
Sidahmed, A.8
Smith, A.J.9
Cramer, E.M.10
-
4
-
-
78149410393
-
Coreceptor usage by HIV-1 and HIV-2 primary isolates: the relevance ofCCR8 chemokine receptor as an alternative coreceptor
-
Calado M., Matoso P., Santos-Costa Q., Espirito-Santo M., Machado J., Rosado L., Antunes F., Mansinho K., Lopes M.M., Maltez F., et al. Coreceptor usage by HIV-1 and HIV-2 primary isolates: the relevance ofCCR8 chemokine receptor as an alternative coreceptor. Virology 2010, 408:174-182.
-
(2010)
Virology
, vol.408
, pp. 174-182
-
-
Calado, M.1
Matoso, P.2
Santos-Costa, Q.3
Espirito-Santo, M.4
Machado, J.5
Rosado, L.6
Antunes, F.7
Mansinho, K.8
Lopes, M.M.9
Maltez, F.10
-
5
-
-
84858060040
-
Natural SIV hosts: showing AIDS the door
-
Chahroudi A., Bosinger S.E., Vanderford T.H., Paiardini M., Silvestri G. Natural SIV hosts: showing AIDS the door. Science 2012, 335:1188-1193.
-
(2012)
Science
, vol.335
, pp. 1188-1193
-
-
Chahroudi, A.1
Bosinger, S.E.2
Vanderford, T.H.3
Paiardini, M.4
Silvestri, G.5
-
6
-
-
0031575431
-
Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
-
Connor R.I., Sheridan K.E., Ceradini D., Choe S., Landau N.R. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J.Exp. Med. 1997, 185:621-628.
-
(1997)
J.Exp. Med.
, vol.185
, pp. 621-628
-
-
Connor, R.I.1
Sheridan, K.E.2
Ceradini, D.3
Choe, S.4
Landau, N.R.5
-
7
-
-
4544288671
-
Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ Tcells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction
-
Fortin J.F., Barat C., Beauséjour Y., Barbeau B., Tremblay M.J. Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ Tcells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction. J.Biol. Chem. 2004, 279:39520-39531.
-
(2004)
J.Biol. Chem.
, vol.279
, pp. 39520-39531
-
-
Fortin, J.F.1
Barat, C.2
Beauséjour, Y.3
Barbeau, B.4
Tremblay, M.J.5
-
8
-
-
41149083421
-
Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis
-
Gordon S.N., Dunham R.M., Engram J.C., Estes J., Wang Z., Klatt N.R., Paiardini M., Pandrea I.V., Apetrei C., Sodora D.L., et al. Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis. J.Virol. 2008, 82:3725-3735.
-
(2008)
J.Virol.
, vol.82
, pp. 3725-3735
-
-
Gordon, S.N.1
Dunham, R.M.2
Engram, J.C.3
Estes, J.4
Wang, Z.5
Klatt, N.R.6
Paiardini, M.7
Pandrea, I.V.8
Apetrei, C.9
Sodora, D.L.10
-
9
-
-
0029795040
-
The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR
-
Grzesiek S., Stahl S.J., Wingfield P.T., Bax A. The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR. Biochemistry 1996, 35:10256-10261.
-
(1996)
Biochemistry
, vol.35
, pp. 10256-10261
-
-
Grzesiek, S.1
Stahl, S.J.2
Wingfield, P.T.3
Bax, A.4
-
10
-
-
0031777694
-
Coreceptor usage of human immunodeficiency virus type 2 primary isolates and biological clones is broad and does not correlate with their syncytium-inducing capacities
-
Guillon C., van der Ende M.E., Boers P.H., Gruters R.A., Schutten M., Osterhaus A.D. Coreceptor usage of human immunodeficiency virus type 2 primary isolates and biological clones is broad and does not correlate with their syncytium-inducing capacities. J.Virol. 1998, 72:6260-6263.
-
(1998)
J.Virol.
, vol.72
, pp. 6260-6263
-
-
Guillon, C.1
van der Ende, M.E.2
Boers, P.H.3
Gruters, R.A.4
Schutten, M.5
Osterhaus, A.D.6
-
11
-
-
79958770579
-
Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly
-
Horenkamp F.A., Breuer S., Schulte A., Lülf S., Weyand M., Saksela K., Geyer M. Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly. Traffic 2011, 12:867-877.
-
(2011)
Traffic
, vol.12
, pp. 867-877
-
-
Horenkamp, F.A.1
Breuer, S.2
Schulte, A.3
Lülf, S.4
Weyand, M.5
Saksela, K.6
Geyer, M.7
-
12
-
-
84861325356
-
Efficient Nef-mediated downmodulation of TCR-CD3 and CD28 is associated with high CD4+ Tcell counts in viremic HIV-2 infection
-
Khalid M., Yu H., Sauter D., Usmani S.M., Schmokel J., Feldman J., Gruters R.A., van der Ende M.E., Geyer M., Rowland-Jones S., et al. Efficient Nef-mediated downmodulation of TCR-CD3 and CD28 is associated with high CD4+ Tcell counts in viremic HIV-2 infection. J.Virol. 2012, 86:4906-4920.
-
(2012)
J.Virol.
, vol.86
, pp. 4906-4920
-
-
Khalid, M.1
Yu, H.2
Sauter, D.3
Usmani, S.M.4
Schmokel, J.5
Feldman, J.6
Gruters, R.A.7
van der Ende, M.E.8
Geyer, M.9
Rowland-Jones, S.10
-
13
-
-
76449090849
-
Pseudo-merohedral twinning and noncrystallographic symmetry in orthorhombic crystals of SIVmac239 Nefcore domain bound to different-length TCRzeta fragments
-
Kim W.M., Sigalov A.B., Stern L.J. Pseudo-merohedral twinning and noncrystallographic symmetry in orthorhombic crystals of SIVmac239 Nefcore domain bound to different-length TCRzeta fragments. Acta Crystallogr. D Biol. Crystallogr. 2010, 66:163-175.
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 163-175
-
-
Kim, W.M.1
Sigalov, A.B.2
Stern, L.J.3
-
14
-
-
51349141354
-
Role of Nef in primate lentiviral immunopathogenesis
-
Kirchhoff F., Schindler M., Specht A., Arhel N., Münch J. Role of Nef in primate lentiviral immunopathogenesis. Cell. Mol. Life Sci. 2008, 65:2621-2636.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 2621-2636
-
-
Kirchhoff, F.1
Schindler, M.2
Specht, A.3
Arhel, N.4
Münch, J.5
-
15
-
-
84856425445
-
Nef surfaces: where to interfere with function
-
Lülf S., Horenkamp F.A., Breuer S., Geyer M. Nef surfaces: where to interfere with function. Curr. HIV Res. 2011, 9:543-551.
-
(2011)
Curr. HIV Res.
, vol.9
, pp. 543-551
-
-
Lülf, S.1
Horenkamp, F.A.2
Breuer, S.3
Geyer, M.4
-
16
-
-
36048989674
-
Virally induced CD4+ Tcell depletion is not sufficient to induce AIDS in a natural host
-
Milush J.M., Reeves J.D., Gordon S.N., Zhou D., Muthukumar A., Kosub D.A., Chacko E., Giavedoni L.D., Ibegbu C.C., Cole K.S., et al. Virally induced CD4+ Tcell depletion is not sufficient to induce AIDS in a natural host. J.Immunol. 2007, 179:3047-3056.
-
(2007)
J.Immunol.
, vol.179
, pp. 3047-3056
-
-
Milush, J.M.1
Reeves, J.D.2
Gordon, S.N.3
Zhou, D.4
Muthukumar, A.5
Kosub, D.A.6
Chacko, E.7
Giavedoni, L.D.8
Ibegbu, C.C.9
Cole, K.S.10
-
17
-
-
79952236823
-
Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ Tcell loss is associated with double-negative Tcells
-
Milush J.M., Mir K.D., Sundaravaradan V., Gordon S.N., Engram J., Cano C.A., Reeves J.D., Anton E., O'Neill E., Butler E., et al. Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ Tcell loss is associated with double-negative Tcells. J.Clin. Invest. 2011, 121:1102-1110.
-
(2011)
J.Clin. Invest.
, vol.121
, pp. 1102-1110
-
-
Milush, J.M.1
Mir, K.D.2
Sundaravaradan, V.3
Gordon, S.N.4
Engram, J.5
Cano, C.A.6
Reeves, J.D.7
Anton, E.8
O'Neill, E.9
Butler, E.10
-
18
-
-
78650623074
-
SIV infection in natural hosts: resolution of immune activation during the acute-to-chronic transition phase
-
Mir K.D., Gasper M.A., Sundaravaradan V., Sodora D.L. SIV infection in natural hosts: resolution of immune activation during the acute-to-chronic transition phase. Microbes Infect. 2011, 13:14-24.
-
(2011)
Microbes Infect.
, vol.13
, pp. 14-24
-
-
Mir, K.D.1
Gasper, M.A.2
Sundaravaradan, V.3
Sodora, D.L.4
-
19
-
-
0742325043
-
The CCR5 and CXCR4 coreceptors-central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection
-
Moore J.P., Kitchen S.G., Pugach P., Zack J.A. The CCR5 and CXCR4 coreceptors-central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res. Hum. Retroviruses 2004, 20:111-126.
-
(2004)
AIDS Res. Hum. Retroviruses
, vol.20
, pp. 111-126
-
-
Moore, J.P.1
Kitchen, S.G.2
Pugach, P.3
Zack, J.A.4
-
20
-
-
0344766077
-
Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage
-
Mörner A., Björndal A., Albert J., Kewalramani V.N., Littman D.R., Inoue R., Thorstensson R., Fenyö E.M., Björling E. Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage. J.Virol. 1999, 73:2343-2349.
-
(1999)
J.Virol.
, vol.73
, pp. 2343-2349
-
-
Mörner, A.1
Björndal, A.2
Albert, J.3
Kewalramani, V.N.4
Littman, D.R.5
Inoue, R.6
Thorstensson, R.7
Fenyö, E.M.8
Björling, E.9
-
21
-
-
79960131812
-
4+ Tcells are associated with limited CCR5 expression
-
4+ Tcells are associated with limited CCR5 expression. Nat. Med. 2011, 17:830-836.
-
(2011)
Nat. Med.
, vol.17
, pp. 830-836
-
-
Paiardini, M.1
Cervasi, B.2
Reyes-Aviles, E.3
Micci, L.4
Ortiz, A.M.5
Chahroudi, A.6
Vinton, C.7
Gordon, S.N.8
Bosinger, S.E.9
Francella, N.10
-
22
-
-
33745070227
-
Nef-mediated suppression of Tcell activation was lost in a lentiviral lineage that gave rise to HIV-1
-
Schindler M., Münch J., Kutsch O., Li H., Santiago M.L., Bibollet-Ruche F., Müller-Trutwin M.C., Novembre F.J., Peeters M., Courgnaud V., et al. Nef-mediated suppression of Tcell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell 2006, 125:1055-1067.
-
(2006)
Cell
, vol.125
, pp. 1055-1067
-
-
Schindler, M.1
Münch, J.2
Kutsch, O.3
Li, H.4
Santiago, M.L.5
Bibollet-Ruche, F.6
Müller-Trutwin, M.C.7
Novembre, F.J.8
Peeters, M.9
Courgnaud, V.10
-
23
-
-
48249157009
-
Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection
-
Schindler M., Schmökel J., Specht A., Li H., Münch J., Khalid M., Sodora D.L., Hahn B.H., Silvestri G., Kirchhoff F. Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection. PLoS Pathog. 2008, 4:e1000107.
-
(2008)
PLoS Pathog.
, vol.4
-
-
Schindler, M.1
Schmökel, J.2
Specht, A.3
Li, H.4
Münch, J.5
Khalid, M.6
Sodora, D.L.7
Hahn, B.H.8
Silvestri, G.9
Kirchhoff, F.10
-
24
-
-
65549084288
-
Conservation of Nef function across highly diverse lineages of SIVsmm
-
Schmökel J., Li H., Bailes E., Schindler M., Silvestri G., Hahn B.H., Apetrei C., Kirchhoff F. Conservation of Nef function across highly diverse lineages of SIVsmm. Retrovirology 2009, 6:36.
-
(2009)
Retrovirology
, vol.6
, pp. 36
-
-
Schmökel, J.1
Li, H.2
Bailes, E.3
Schindler, M.4
Silvestri, G.5
Hahn, B.H.6
Apetrei, C.7
Kirchhoff, F.8
-
25
-
-
15244351478
-
Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts
-
Silvestri G., Fedanov A., Germon S., Kozyr N., Kaiser W.J., Garber D.A., McClure H., Feinberg M.B., Staprans S.I. Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts. J.Virol. 2005, 79:4043-4054.
-
(2005)
J.Virol.
, vol.79
, pp. 4043-4054
-
-
Silvestri, G.1
Fedanov, A.2
Germon, S.3
Kozyr, N.4
Kaiser, W.J.5
Garber, D.A.6
McClure, H.7
Feinberg, M.B.8
Staprans, S.I.9
-
26
-
-
33846514830
-
Correlates of preserved CD4(+) Tcell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis
-
Sumpter B., Dunham R., Gordon S., Engram J., Hennessy M., Kinter A., Paiardini M., Cervasi B., Klatt N., McClure H., et al. Correlates of preserved CD4(+) Tcell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis. J.Immunol. 2007, 178:1680-1691.
-
(2007)
J.Immunol.
, vol.178
, pp. 1680-1691
-
-
Sumpter, B.1
Dunham, R.2
Gordon, S.3
Engram, J.4
Hennessy, M.5
Kinter, A.6
Paiardini, M.7
Cervasi, B.8
Klatt, N.9
McClure, H.10
-
27
-
-
84879519659
-
Multifunctional double-negative Tcells in sooty mangabeys mediate T-helper functions irrespective of SIV infection
-
Sundaravaradan V., Saleem R., Micci L., Gasper M.A., Ortiz A.M., Else J., Silvestri G., Paiardini M., Aitchison J.D., Sodora D.L. Multifunctional double-negative Tcells in sooty mangabeys mediate T-helper functions irrespective of SIV infection. PLoS Pathog. 2013, 9:e1003441.
-
(2013)
PLoS Pathog.
, vol.9
-
-
Sundaravaradan, V.1
Saleem, R.2
Micci, L.3
Gasper, M.A.4
Ortiz, A.M.5
Else, J.6
Silvestri, G.7
Paiardini, M.8
Aitchison, J.D.9
Sodora, D.L.10
-
28
-
-
0038758782
-
Cooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis
-
Swigut T., Greenberg M., Skowronski J. Cooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis. J.Virol. 2003, 77:8116-8126.
-
(2003)
J.Virol.
, vol.77
, pp. 8116-8126
-
-
Swigut, T.1
Greenberg, M.2
Skowronski, J.3
-
29
-
-
77951990027
-
A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation
-
Taaffe J., Chahroudi A., Engram J., Sumpter B., Meeker T., Ratcliffe S., Paiardini M., Else J., Silvestri G. A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation. J.Virol. 2010, 84:5476-5484.
-
(2010)
J.Virol.
, vol.84
, pp. 5476-5484
-
-
Taaffe, J.1
Chahroudi, A.2
Engram, J.3
Sumpter, B.4
Meeker, T.5
Ratcliffe, S.6
Paiardini, M.7
Else, J.8
Silvestri, G.9
-
30
-
-
79955037084
-
Persistence and emergence of X4virus in HIV infection
-
Weinberger A.D., Perelson A.S. Persistence and emergence of X4virus in HIV infection. Math. Biosci. Eng. 2011, 8:605-626.
-
(2011)
Math. Biosci. Eng.
, vol.8
, pp. 605-626
-
-
Weinberger, A.D.1
Perelson, A.S.2
-
31
-
-
0032505013
-
Adaptation to promiscuous usage of CC and CXC-chemokine coreceptors invivo correlates with HIV-1 disease progression
-
Xiao L., Rudolph D.L., Owen S.M., Spira T.J., Lal R.B. Adaptation to promiscuous usage of CC and CXC-chemokine coreceptors invivo correlates with HIV-1 disease progression. AIDS 1998, 12:F137-F143.
-
(1998)
AIDS
, vol.12
-
-
Xiao, L.1
Rudolph, D.L.2
Owen, S.M.3
Spira, T.J.4
Lal, R.B.5
|