Sesamin ameliorates doxorubicin-induced cardiotoxicity: Involvement of Sirt1 and Mn-SOD pathway

Toxicology Letters

Volumn 224, Issue 2, 2014, Pages 257-263

  Su, Suwen ^a   Li, Qian ^a   liu, Yi ^a   Xiong, Chen ^a   Li, Junxia ^a   Zhang, Rong ^a   Niu, Yujie ^a   Zhao, Lijuan ^a   Wang, Yongli ^a   Guo, Huicai ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Cardiotoxicity; Doxorubicin; Mn SOD; Sesamin; Sirt1

Indexed keywords

CREATINE KINASE MB; DOXORUBICIN; EX 527; HYDROLASE INHIBITOR; MANGANESE SUPEROXIDE DISMUTASE; NICOTINAMIDE; SESAMIN; SIRTUIN 1; SIRTUIN 1 SPECIFIC INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOTOXICITY; CELL DAMAGE; CONTROLLED STUDY; HEART; HEART MUSCLE CELL; HEART PROTECTION; MALE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE; CARDIOTOXICITY; DOX; DOXORUBICIN; MALONDIALDEHYDE; MANGANESE SOD; MDA; MN-SOD; MTT; REACTIVE OXYGEN SPECIES; ROS; SES; SESAMIN; SIRT1; SIRTUIN 1;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIOXIDANTS; DIOXOLES; DOXORUBICIN; HEART; LIGNANS; MALE; MYOCYTES, CARDIAC; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SIRTUIN 1; SUPEROXIDE DISMUTASE;

EID: 84888418518     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.10.034     Document Type: Article

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