Hypercapnic acidosis confers antioxidant and anti-apoptosis effects against ventilator-induced lung injury

Laboratory Investigation

Volumn 93, Issue 12, 2013, Pages 1339-1349

  Yang, Wan Chao ^a   Song, Chun Yu ^a   Wang, Nan ^a   Zhang, Li Li ^a   Yue, Zi Yong ^a,b   Cui, Xiao Guang ^a,b   Zhou, Hua Cheng ^a,b  

^a THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

autophagy; endoplasmic reticulum stress; HFE; iron overload; unfolded protein response

Indexed keywords

ANTIOXIDANT; APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE 3; CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE;

ACIDOSIS; AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; ENZYME ACTIVATION; GAS EXCHANGE; HYPERCAPNIA; HYPERCAPNIC ACIDOSIS; LUNG; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; MALE; NONHUMAN; OXIDATIVE STRESS; OXYGENATION; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; VENTILATOR INDUCED LUNG INJURY; ANIMAL; HEMODYNAMICS; MECHANICAL STRESS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VENTILATOR-INDUCED LUNG INJURY;

ACIDOSIS; ANIMALS; APOPTOSIS; HEMODYNAMICS; HYPERCAPNIA; MALE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RESPIRATION, ARTIFICIAL; STRESS, MECHANICAL; VENTILATOR-INDUCED LUNG INJURY;

EID: 84888344964     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2013.118     Document Type: Article

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