The fate of CD4 + T cells under tolerance-inducing stimulation: A modeling perspective

Immunology and Cell Biology

Volumn 91, Issue 10, 2013, Pages 652-660

  Caridade, Marta ^a,b   Oliveira, Vanessa G ^a,b   Agua Doce, Ana ^a,b   Graca, Luis ^a,b   Ribeiro, Ruy M ^a,c  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^c LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

anti CD4; Foxp3; immune tolerance; mathematical modeling; proliferation kinetics

Indexed keywords

OKT 4; PROTEIN BCL XL; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; CD4+ T LYMPHOCYTE; CELL COUNT; CONTROLLED STUDY; GRAFT REJECTION; HALF LIFE TIME; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MATHEMATICAL MODEL; MOUSE; NONHUMAN; REGULATORY T LYMPHOCYTE; REVIEW; SKIN GRAFT; SPLEEN CELL; T CELL CULTURE; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE; TRANSPLANTATION TOLERANCE; ULTRAVIOLET RADIATION; UPREGULATION;

ANIMALIA; MUS MUSCULUS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; APOPTOSIS; BCL-X PROTEIN; CD4-POSITIVE T-LYMPHOCYTES; CELL LINEAGE; CELL PROLIFERATION; CELLS, CULTURED; CONFIDENCE INTERVALS; FORKHEAD TRANSCRIPTION FACTORS; IMMUNE TOLERANCE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MICE; MODELS, IMMUNOLOGICAL; SKIN TRANSPLANTATION; TIME FACTORS;

EID: 84888342216     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2013.63     Document Type: Review

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