Inhibition of checkpoint kinase 2 (CHK2) enhances sensitivity of pancreatic adenocarcinoma cells to gemcitabine

Journal of Cellular and Molecular Medicine

Volumn 17, Issue 10, 2013, Pages 1261-1270

  Duong, Hong Quan ^a,b   Hong, Young Bin ^a,e   Kim, Jung Soon ^b   Lee, Hee Seok ^b   Yi, Yong Weon ^a,b   Kim, Yeon Jeong ^b   Wang, Antai ^c   Zhao, Wenjing ^c   Cho, Chi Heum ^d   Seong, Yeon Sun ^b   Bae, Insoo ^a,b  

^a GEORGETOWN UNIVERSITY   (United States)

^b Dankook University   (South Korea)

^c Howard Hughes Medical Institute   (United States)

^d Keimyung University School of Medicine   (South Korea)

^e Ewha Womans University School of Medicine   (South Korea)

Author keywords

Checkpoint kinase 2 (CHK2) inhibitor; Combination; Gemcitabine; NSC109555; Pancreatic adenocarcinoma; Synergism

Indexed keywords

AGOUTI PACA;

ANTINEOPLASTIC ANTIMETABOLITE; CHECKPOINT KINASE 2; DEOXYCYTIDINE; DRUG DERIVATIVE; GEMCITABINE; REACTIVE OXYGEN METABOLITE;

ADENOCARCINOMA; APOPTOSIS; ARTICLE; CHECKPOINT KINASE 2 (CHK2) INHIBITOR; COMBINATION; DRUG ANTAGONISM; HUMAN; METABOLISM; NSC109555; PANCREAS ADENOCARCINOMA; PANCREAS TUMOR; PATHOLOGY; PHOSPHORYLATION; SYNERGISM; TUMOR CELL LINE; WESTERN BLOTTING;

CHECKPOINT KINASE 2 (CHK2) INHIBITOR; COMBINATION; GEMCITABINE; NSC109555; PANCREATIC ADENOCARCINOMA; SYNERGISM;

ADENOCARCINOMA; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CHECKPOINT KINASE 2; DEOXYCYTIDINE; HUMANS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES;

EID: 84888342168     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12101     Document Type: Article

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