Structural determinants of drug partitioning in surrogates of phosphatidylcholine bilayer strata

Molecular Pharmaceutics

Volumn 10, Issue 10, 2013, Pages 3684-3696

  Lukacova, Viera ^a,d   Natesan, Senthil ^b   Peng, Ming ^a   Tandlich, Roman ^c   Wang, Zhanbin ^b   Lynch, Sandra ^b   Subramaniam, Rajesh ^b   Balaz, Stefan ^b  

^a NORTH DAKOTA STATE UNIVERSITY   (United States)

^b ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

^c RHODES UNIVERSITY   (South Africa)

^d Simulations Plus Inc   (United States)

Author keywords

Bilayer; Core; Diacetyl phosphatidylcholine (DAcPC); Headgroups; Hexadecane; Interface; Partition coefficient; Phosphatidylcholine; Phospholipid; Transfer energy

Indexed keywords

AROMATIC COMPOUND; DIACETYL PHOSPHATIDYLCHOLINE; DRUG; HEXADECANE; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG BINDING; DRUG TRANSPORT; HYDROGEN BOND; PARTITION COEFFICIENT; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; SOLVATION; STRUCTURE ANALYSIS;

ALKANES; LIPID BILAYERS; MODELS, THEORETICAL; PHOSPHATIDYLCHOLINES; PHOSPHOLIPIDS;

EID: 84888334273     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400204y     Document Type: Article

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