The structure of Irisin reveals a novel intersubunit β-sheet fibronectin type III (FNIII) dimer: Implications for receptor activation

Journal of Biological Chemistry

Volumn 288, Issue 47, 2013, Pages 33738-33744

  Schumacher, Maria A ^a   Chinnam, Nagababu ^a   Ohashi, Tomoo ^a   Shah, Riddhi Sanjay ^a   Erickson, Harold P ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; DIMERIZATION; DIMERS; ENERGY DISSIPATION; PROTEINS;

BIOCHEMICAL CHARACTERIZATION; FIBRONECTIN DOMAINS; FIBRONECTIN TYPE III; METABOLIC DISORDERS; MOLECULAR MECHANISM; NEURONAL DEVELOPMENT; POSSIBLE MECHANISMS; RECEPTOR ACTIVATION;

CRYSTAL STRUCTURE;

DIMER; FIBRONECTIN; FIBRONECTIN 3; FNDC5 PROTEIN; IRISIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DIMERIZATION; EMBRYO; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTEIN SUBUNIT;

EXERCISE; HORMONES; MUSCLE; RECEPTORS; X-RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; FIBRONECTINS; GLYCOSYLATION; HUMANS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84888323854     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.516641     Document Type: Article

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