-
1
-
-
50149086108
-
Diversity of degradation signals in the ubiquitin-proteasome system
-
Ravid, T., and Hochstrasser, M. (2008) Diversity of degradation signals in the ubiquitin-proteasome system. Nat. Rev. Mol. Cell Biol. 9, 679-690
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 679-690
-
-
Ravid, T.1
Hochstrasser, M.2
-
2
-
-
0034602845
-
Recognition of the polyubiquitin proteolytic signal
-
Thrower, J. S., Hoffman, L., Rechsteiner, M., and Pickart, C. M. (2000) Recognition of the polyubiquitin proteolytic signal. EMBO J. 19, 94-102
-
(2000)
EMBO J.
, vol.19
, pp. 94-102
-
-
Thrower, J.S.1
Hoffman, L.2
Rechsteiner, M.3
Pickart, C.M.4
-
3
-
-
0028234770
-
Distinct 19 S and20Ssubcomplexes ofthe26Sproteasome and their distribution inthe nucleus and the cytoplasm
-
Peters, J. M., Franke, W. W., and Kleinschmidt, J. A. (1994) Distinct 19 S and20Ssubcomplexes ofthe26Sproteasome and their distribution inthe nucleus and the cytoplasm. J. Biol. Chem. 269, 7709-7718
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7709-7718
-
-
Peters, J.M.1
Franke, W.W.2
Kleinschmidt, J.A.3
-
4
-
-
84878942836
-
Molecular architecture and assembly of the eukaryotic proteasome
-
Tomko, R. J., Jr., and Hochstrasser, M. (2013) Molecular architecture and assembly of the eukaryotic proteasome. Annu. Rev. Biochem. 82, 415-445
-
(2013)
Annu. Rev. Biochem.
, vol.82
, pp. 415-445
-
-
Tomko Jr., R.J.1
Hochstrasser, M.2
-
5
-
-
26844433577
-
Proteasome-associated proteins. Regulation of a proteolytic machine
-
Schmidt, M., Hanna, J., Elsasser, S., and Finley, D. (2005) Proteasome-associated proteins. Regulation of a proteolytic machine. Biol. Chem. 386, 725-737
-
(2005)
Biol. Chem.
, vol.386
, pp. 725-737
-
-
Schmidt, M.1
Hanna, J.2
Elsasser, S.3
Finley, D.4
-
6
-
-
0025913947
-
Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression
-
Fröhlich, K. U., Fries, H. W., Rüdiger, M., Erdmann, R., Botstein, D., and Mecke, D. (1991) Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression. J. Cell Biol. 114, 443-453
-
(1991)
J. Cell Biol.
, vol.114
, pp. 443-453
-
-
Fröhlich, K.U.1
Fries, H.W.2
Rüdiger, M.3
Erdmann, R.4
Botstein, D.5
Mecke, D.6
-
7
-
-
0025314878
-
An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF
-
Peters, J. M., Walsh, M. J., and Franke, W. W. (1990) An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF. EMBO J. 9, 1757-1767
-
(1990)
EMBO J.
, vol.9
, pp. 1757-1767
-
-
Peters, J.M.1
Walsh, M.J.2
Franke, W.W.3
-
8
-
-
0035818999
-
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
-
Ye, Y., Meyer, H. H., and Rapoport, T. A. (2001) The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 414, 652-656
-
(2001)
Nature
, vol.414
, pp. 652-656
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
-
9
-
-
0036136901
-
AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation
-
Rabinovich, E., Kerem, A., Fröhlich, K. U., Diamant, N., and Bar-Nun, S. (2002) AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation. Mol. Cell. Biol. 22, 626-634
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 626-634
-
-
Rabinovich, E.1
Kerem, A.2
Fröhlich, K.U.3
Diamant, N.4
Bar-Nun, S.5
-
10
-
-
0035658442
-
HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins
-
Bays, N. W., Wilhovsky, S. K., Goradia, A., Hodgkiss-Harlow, K., and Hampton, R. Y. (2001) HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol. Biol. Cell 12, 4114-4128
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 4114-4128
-
-
Bays, N.W.1
Wilhovsky, S.K.2
Goradia, A.3
Hodgkiss-Harlow, K.4
Hampton, R.Y.5
-
11
-
-
0029814693
-
Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae
-
Ghislain, M., Dohmen, R. J., Levy, F., and Varshavsky, A. (1996) Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae. EMBO J. 15, 4884-4899
-
(1996)
EMBO J.
, vol.15
, pp. 4884-4899
-
-
Ghislain, M.1
Dohmen, R.J.2
Levy, F.3
Varshavsky, A.4
-
12
-
-
0035977095
-
Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48 (UFD1/NPL4), a ubiquitin-selective chaperone
-
Rape, M., Hoppe, T., Gorr, I., Kalocay, M., Richly, H., and Jentsch, S. (2001) Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48 (UFD1/NPL4), a ubiquitin-selective chaperone. Cell 107, 667-677
-
(2001)
Cell
, vol.107
, pp. 667-677
-
-
Rape, M.1
Hoppe, T.2
Gorr, I.3
Kalocay, M.4
Richly, H.5
Jentsch, S.6
-
13
-
-
0037084028
-
Role of the ubiquitin-selective CDC48 (UFD1/NPL4) chaperone (segregase) in ERAD of OLE1 and other substrates
-
Braun, S., Matuschewski, K., Rape, M., Thoms, S., and Jentsch, S. (2002) Role of the ubiquitin-selective CDC48 (UFD1/NPL4) chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J. 21, 615-621
-
(2002)
EMBO J.
, vol.21
, pp. 615-621
-
-
Braun, S.1
Matuschewski, K.2
Rape, M.3
Thoms, S.4
Jentsch, S.5
-
14
-
-
0141507032
-
Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains
-
De La Barre, B., and Brunger, A. T. (2003) Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains. Nat. Struct. Biol. 10, 856-863
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 856-863
-
-
De La Barre, B.1
Brunger, A.T.2
-
15
-
-
0344983310
-
The crystal structure of murine p97/VCP at 3. 6 Å
-
Huyton, T., Pye, V. E., Briggs, L. C., Flynn, T. C., Beuron, F., Kondo, H., Ma, J., Zhang, X., and Freemont, P. S. (2003) The crystal structure of murine p97/VCP at 3. 6 Å. J. Struct. Biol. 144, 337-348
-
(2003)
J. Struct. Biol.
, vol.144
, pp. 337-348
-
-
Huyton, T.1
Pye, V.E.2
Briggs, L.C.3
Flynn, T.C.4
Beuron, F.5
Kondo, H.6
Ma, J.7
Zhang, X.8
Freemont, P.S.9
-
16
-
-
1842576796
-
Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47
-
Dreveny, I., Kondo, H., Uchiyama, K., Shaw, A., Zhang, X., and Freemont, P. S. (2004) Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. EMBO J. 23, 1030-1039
-
(2004)
EMBO J.
, vol.23
, pp. 1030-1039
-
-
Dreveny, I.1
Kondo, H.2
Uchiyama, K.3
Shaw, A.4
Zhang, X.5
Freemont, P.S.6
-
17
-
-
0035896011
-
The UBX domain. A widespread ubiquitin-like module
-
Buchberger, A., Howard, M. J., Proctor, M., and Bycroft, M. (2001) The UBX domain. A widespread ubiquitin-like module. J. Mol. Biol. 307, 17-24
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 17-24
-
-
Buchberger, A.1
Howard, M.J.2
Proctor, M.3
Bycroft, M.4
-
18
-
-
0030790695
-
P47 is a cofactor for p97-mediated membrane fusion
-
Kondo, H., Rabouille, C., Newman, R., Levine, T. P., Pappin, D., Freemont, P., and Warren, G. (1997) p47 is a cofactor for p97-mediated membrane fusion. Nature 388, 75-78
-
(1997)
Nature
, vol.388
, pp. 75-78
-
-
Kondo, H.1
Rabouille, C.2
Newman, R.3
Levine, T.P.4
Pappin, D.5
Freemont, P.6
Warren, G.7
-
19
-
-
0037049466
-
VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo
-
Uchiyama, K., Jokitalo, E., Kano, F., Murata, M., Zhang, X., Canas, B., Newman, R., Rabouille, C., Pappin, D., Freemont, P., and Kondo, H. (2002) VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. J. Cell Biol. 159, 855-866
-
(2002)
J. Cell Biol.
, vol.159
, pp. 855-866
-
-
Uchiyama, K.1
Jokitalo, E.2
Kano, F.3
Murata, M.4
Zhang, X.5
Canas, B.6
Newman, R.7
Rabouille, C.8
Pappin, D.9
Freemont, P.10
Kondo, H.11
-
20
-
-
27144535945
-
Ubx2 links the Cdc48 complex to ER-associated protein degradation
-
Neuber, O., Jarosch, E., Volkwein, C., Walter, J., and Sommer, T. (2005) Ubx2 links the Cdc48 complex to ER-associated protein degradation. Nat. Cell. Biol. 7, 993-998
-
(2005)
Nat. Cell. Biol.
, vol.7
, pp. 993-998
-
-
Neuber, O.1
Jarosch, E.2
Volkwein, C.3
Walter, J.4
Sommer, T.5
-
21
-
-
78650733298
-
Cdc48/p97 mediates UV-dependent turnover of RNA Pol II
-
Verma, R., Oania, R., Fang, R., Smith, G. T., and Deshaies, R. J. (2011) Cdc48/p97 mediates UV-dependent turnover of RNA Pol II. Mol. Cell 41, 82-92
-
(2011)
Mol. Cell
, vol.41
, pp. 82-92
-
-
Verma, R.1
Oania, R.2
Fang, R.3
Smith, G.T.4
Deshaies, R.J.5
-
22
-
-
0034658270
-
A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways
-
Meyer, H. H., Shorter, J. G., Seemann, J., Pappin, D., and Warren, G. (2000) A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways. EMBO J. 19, 2181-2192
-
(2000)
EMBO J.
, vol.19
, pp. 2181-2192
-
-
Meyer, H.H.1
Shorter, J.G.2
Seemann, J.3
Pappin, D.4
Warren, G.5
-
23
-
-
0034746779
-
The conserved npl4 protein complex mediates proteasomedependent membrane-bound transcription factor activation
-
Hitchcock, A. L., Krebber, H., Frietze, S., Lin, A., Latterich, M., and Silver, P. A. (2001) The conserved npl4 protein complex mediates proteasomedependent membrane-bound transcription factor activation. Mol. Biol. Cell 12, 3226-3241
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 3226-3241
-
-
Hitchcock, A.L.1
Krebber, H.2
Frietze, S.3
Lin, A.4
Latterich, M.5
Silver, P.A.6
-
24
-
-
9644255751
-
The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism
-
Bruderer, R. M., Brasseur, C., and Meyer, H. H. (2004) The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism. J. Biol. Chem. 279, 49609-49616
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49609-49616
-
-
Bruderer, R.M.1
Brasseur, C.2
Meyer, H.H.3
-
25
-
-
0036173013
-
Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48
-
Jarosch, E., Taxis, C., Volkwein, C., Bordallo, J., Finley, D., Wolf, D. H., and Sommer, T. (2002) Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat. Cell Biol. 4, 134-139
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 134-139
-
-
Jarosch, E.1
Taxis, C.2
Volkwein, C.3
Bordallo, J.4
Finley, D.5
Wolf, D.H.6
Sommer, T.7
-
26
-
-
78149429951
-
A stress-responsive system for mitochondrial protein degradation
-
Heo, J. M., Livnat-Levanon, N., Taylor, E. B., Jones, K. T., Dephoure, N., Ring, J., Xie, J., Brodsky, J. L., Madeo, F., Gygi, S. P., Ashrafi, K., Glickman, M. H., and Rutter, J. (2010) A stress-responsive system for mitochondrial protein degradation. Mol. Cell 40, 465-480
-
(2010)
Mol. Cell
, vol.40
, pp. 465-480
-
-
Heo, J.M.1
Livnat-Levanon, N.2
Taylor, E.B.3
Jones, K.T.4
Dephoure, N.5
Ring, J.6
Xie, J.7
Brodsky, J.L.8
Madeo, F.9
Gygi, S.P.10
Ashrafi, K.11
Glickman, M.H.12
Rutter, J.13
-
27
-
-
79953152149
-
A Cdc48p-associated factor modulates endoplasmic reticulum-associated degradation, cell stress, and ubiquitinated protein homeostasis
-
Tran, J. R., Tomsic, L. R., and Brodsky, J. L. (2011) A Cdc48p-associated factor modulates endoplasmic reticulum-associated degradation, cell stress, and ubiquitinated protein homeostasis. J. Biol. Chem. 286, 5744-5755
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 5744-5755
-
-
Tran, J.R.1
Tomsic, L.R.2
Brodsky, J.L.3
-
28
-
-
0025994140
-
Guide to yeast genetics and molecular biology
-
Guthrie, C., and Fink, G. R. (eds) (1991) Guide to yeast genetics and molecular biology. Methods Enzymol. 194, 1-863
-
(1991)
Methods Enzymol.
, vol.194
, pp. 1-863
-
-
Guthrie, C.1
Fink, G.R.2
-
29
-
-
16544395270
-
Site-directed, ligaseindependent mutagenesis (SLIM). A single-tube methodology approaching 100% efficiency in 4 h
-
Chiu, J., March, P. E., Lee, R., and Tillett, D. (2004) Site-directed, ligaseindependent mutagenesis (SLIM). A single-tube methodology approaching 100% efficiency in 4 h. Nucleic Acids Res. 32, e174
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Chiu, J.1
March, P.E.2
Lee, R.3
Tillett, D.4
-
30
-
-
33745225170
-
The delitto perfetto approach to in vivo site-directed mutagenesis and chromosome rearrangements with synthetic oligonucleotides in yeast
-
Storici, F., and Resnick, M. A. (2006) The delitto perfetto approach to in vivo site-directed mutagenesis and chromosome rearrangements with synthetic oligonucleotides in yeast. Methods Enzymol. 409, 329-345
-
(2006)
Methods Enzymol.
, vol.409
, pp. 329-345
-
-
Storici, F.1
Resnick, M.A.2
-
31
-
-
84858246318
-
Disulfide engineering to map subunit interactions in the proteasome and other macromolecular complexes
-
Hochstrasser, M., and Funakoshi, M. (2012) Disulfide engineering to map subunit interactions in the proteasome and other macromolecular complexes. Methods Mol. Biol. 832, 349-362
-
(2012)
Methods Mol. Biol.
, vol.832
, pp. 349-362
-
-
Hochstrasser, M.1
Funakoshi, M.2
-
32
-
-
68549127159
-
Systematical optimization of reverse-phase chromatography for shotgun proteomics
-
Xu, P., Duong, D. M., and Peng, J. (2009) Systematical optimization of reverse-phase chromatography for shotgun proteomics. J. Proteome Res. 8, 3944-3950
-
(2009)
J. Proteome Res.
, vol.8
, pp. 3944-3950
-
-
Xu, P.1
Duong, D.M.2
Peng, J.3
-
33
-
-
0037277179
-
Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis. The yeast proteome
-
Peng, J., Elias, J. E., Thoreen, C. C., Licklider, L. J., and Gygi, S. P. (2003) Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis. The yeast proteome. J. Proteome Res. 2, 43-50
-
(2003)
J. Proteome Res.
, vol.2
, pp. 43-50
-
-
Peng, J.1
Elias, J.E.2
Thoreen, C.C.3
Licklider, L.J.4
Gygi, S.P.5
-
34
-
-
0025853324
-
The short-lived MAT a2 transcriptional regulator is ubiquitinated in vivo
-
Hochstrasser, M., Ellison, M. J., Chau, V., and Varshavsky, A. (1991) The short-lived MAT a2 transcriptional regulator is ubiquitinated in vivo. Proc. Natl. Acad. Sci. U. S. A. 88, 4606-4610
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 4606-4610
-
-
Hochstrasser, M.1
Ellison, M.J.2
Chau, V.3
Varshavsky, A.4
-
35
-
-
84255162055
-
Incorporation of the Rpn12 subunit couples completion of proteasome regulatory particle lid assembly to lid-base joining
-
Tomko, R. J., Jr., and Hochstrasser, M. (2011) Incorporation of the Rpn12 subunit couples completion of proteasome regulatory particle lid assembly to lid-base joining. Mol. Cell 44, 907-917
-
(2011)
Mol. Cell
, vol.44
, pp. 907-917
-
-
Tomko Jr., R.J.1
Hochstrasser, M.2
-
36
-
-
0027198563
-
Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT a2 repressor
-
Chen, P., Johnson, P., Sommer, T., Jentsch, S., and Hochstrasser, M. (1993) Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT a2 repressor. Cell 74, 357-369
-
(1993)
Cell
, vol.74
, pp. 357-369
-
-
Chen, P.1
Johnson, P.2
Sommer, T.3
Jentsch, S.4
Hochstrasser, M.5
-
37
-
-
0033004441
-
Rpn4p acts as a transcription factor by binding to PACE, a nonamer box found upstream of 26S proteasomal and other genes in yeast
-
Mannhaupt, G., Schnall, R., Karpov, V., Vetter, I., and Feldmann, H. (1999) Rpn4p acts as a transcription factor by binding to PACE, a nonamer box found upstream of 26S proteasomal and other genes in yeast. FEBS Lett. 450, 27-34
-
(1999)
FEBS Lett.
, vol.450
, pp. 27-34
-
-
Mannhaupt, G.1
Schnall, R.2
Karpov, V.3
Vetter, I.4
Feldmann, H.5
-
38
-
-
0035853037
-
RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome. A negative feedback circuit
-
Xie, Y., and Varshavsky, A. (2001) RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome. A negative feedback circuit. Proc. Natl. Acad. Sci. U. S. A. 98, 3056-3061
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 3056-3061
-
-
Xie, Y.1
Varshavsky, A.2
-
39
-
-
79959214387
-
Functional diversification of the RING finger and other binuclear treble clef domains in prokaryotes and the early evolution of the ubiquitin system
-
Burroughs, A. M., Iyer, L. M., and Aravind, L. (2011) Functional diversification of the RING finger and other binuclear treble clef domains in prokaryotes and the early evolution of the ubiquitin system. Mol. Biosyst. 7, 2261-2277
-
(2011)
Mol. Biosyst.
, vol.7
, pp. 2261-2277
-
-
Burroughs, A.M.1
Iyer, L.M.2
Aravind, L.3
-
40
-
-
44349160257
-
Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans
-
Yun, C, Stanhill, A., Yang, Y., Zhang, Y., Haynes, C. M., Xu, C. F., Neubert, T. A., Mor, A., Philips, M. R., and Ron, D. (2008) Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 105, 7094-7099
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 7094-7099
-
-
Yun, C.S.A.1
Yang, Y.2
Zhang, Y.3
Haynes, C.M.4
Xu, C.F.5
Neubert, T.A.6
Mor, A.7
Philips, M.R.8
Ron, D.9
-
41
-
-
33748439489
-
An arseniteinducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity
-
Stanhill, A., Haynes, C M., Zhang, Y., Min, G., Steele, M. C, Kalinina, J., Martinez, E., Pickart, C. M., Kong, X. P., and Ron, D. (2006) An arseniteinducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity. Mol. Cell 23, 875-885
-
(2006)
Mol. Cell
, vol.23
, pp. 875-885
-
-
Stanhill, A.1
Haynes, C.M.2
Zhang, Y.3
Min, G.4
Steele, M.C.5
Kalinina, J.6
Martinez, E.7
Pickart, C.M.8
Kong, X.P.9
Ron, D.10
-
42
-
-
84875707717
-
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
-
Australian Cancer Study, Australian Ovarian Cancer Study Group, 370e1-2
-
Pharoah, P. D., Tsai, Y. Y., Ramus, S. J., Phelan, C. M., Goode, E. L., Lawrenson, K., Buckley, M., Fridley, B. L., Tyrer, J. P., Shen, H, Weber, R., Karevan, R., Larson, M. C, Song, H, Tessier, D. C, Bacot, F., Vincent, D., Cunningham, J. M., Dennis, J., Dicks, E., Australian Cancer Study, Australian Ovarian Cancer Study Group, Aben, K. K., Anton-Culver, H., Antonenkova, N., Armasu, S. M., Baglietto, L., Bandera, E. V., Beckmann, M. W., Birrer, M. J., Bloom, G., Bogdanova, N., Brenton, J. D., Brinton, L. A., Brooks-Wilson, A., Brown, R., Butzow, R., Campbell, I., Carney, M. E., Carvalho, R. S., Chang-Claude, J., Chen, Y. A., Chen, Z., Chow, W. H., Cicek, M. S., Coetzee, G., Cook, L. S., Cramer, D. W., Cybulski, C, Dansonka-Mieszkowska, A., Despierre, E., et al. (2013) GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet. 45, 362-370, 370e1-2
-
(2013)
Nat Genet.
, vol.45
, pp. 362-370
-
-
Pharoah, P.D.1
Tsai, Y.Y.2
Ramus, S.J.3
Phelan, C.M.4
Goode, E.L.5
Lawrenson, K.6
Buckley, M.7
Fridley, B.L.8
Tyrer, J.P.9
Shen, H.W.R.10
Karevan, R.11
Larson, M.C.12
Song, H.13
Tessier, D.C.14
Bacot, F.15
Vincent, D.16
Cunningham, J.M.17
Dennis, J.18
Dicks, E.19
Aben, K.K.20
Anton-Culver, H.21
Antonenkova, N.22
Armasu, S.M.23
Baglietto, L.24
Bandera, E.V.25
Beckmann, M.W.26
Birrer, M.J.27
Bloom, G.28
Bogdanova, N.29
Brenton, J.D.30
Brinton, L.A.31
Brooks-Wilson, A.32
Brown, R.33
Butzow, R.34
Campbell, I.35
Carney, M.E.36
Carvalho, R.S.37
Chang-Claude, J.38
Chen, Y.A.39
Chen, Z.40
Chow, W.H.41
Cicek, M.S.42
Coetzee, G.43
Cook, L.S.44
Cramer, D.W.45
Cybulski, C.46
Dansonka-Mieszkowska, A.47
Despierre, E.48
more..
-
43
-
-
63849246525
-
Protein structure prediction on the Web. A case study using the Phyre server
-
Kelley, L. A., and Sternberg, M. J. (2009) Protein structure prediction on the Web. A case study using the Phyre server. Nat. Protoc. 4, 363-371
-
(2009)
Nat. Protoc.
, vol.4
, pp. 363-371
-
-
Kelley, L.A.1
Sternberg, M.J.2
-
44
-
-
84855188325
-
The Cdc48 machine in endoplasmic reticulum associated protein degradation
-
Wolf, D. H, and Stolz, A. (2012) The Cdc48 machine in endoplasmic reticulum associated protein degradation. Biochim. Biophys. Acta 1823, 117-124
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 117-124
-
-
Wolf, D.H.1
Stolz, A.2
-
45
-
-
80053299005
-
Cdc48. Apower machine in protein degradation
-
Stolz, A., Hilt, W., Buchberger, A., and Wolf, D. H. (2011) Cdc48. Apower machine in protein degradation. Trends Biochem. Sci. 36, 515-523
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 515-523
-
-
Stolz, A.1
Hilt, W.2
Buchberger, A.3
Wolf, D.H.4
-
46
-
-
0029119522
-
A proteolytic pathway that recognizes ubiquitin as a degradation signal
-
Johnson, E. S., Ma, P. C, Ota, I. M., and Varshavsky, A. (1995) A proteolytic pathway that recognizes ubiquitin as a degradation signal. J. Biol. Chem. 270, 17442-17456
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17442-17456
-
-
Johnson, E.S.1
Ma, P.C.2
Ota, I.M.3
Varshavsky, A.4
-
47
-
-
0029838640
-
ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway
-
Hiller, M. M., Finger, A., Schweiger, M., and Wolf, D. H. (1996) ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway. Science 273, 1725-1728
-
(1996)
Science
, vol.273
, pp. 1725-1728
-
-
Hiller, M.M.1
Finger, A.2
Schweiger, M.3
Wolf, D.H.4
-
48
-
-
79953768271
-
Control of ubiquitin conjugation by cdc48 and its cofactors
-
Buchberger, A. (2010) Control of ubiquitin conjugation by cdc48 and its cofactors. Subcell. Biochem. 54, 17-30
-
(2010)
Subcell. Biochem.
, vol.54
, pp. 17-30
-
-
Buchberger, A.1
-
49
-
-
51749093587
-
Characterization of the proteasome interaction network using a QTAX-based tag-team strategy and protein interaction network analysis
-
Guerrero, C, Milenkovic, T., Przulj, N., Kaiser, P., and Huang, L. (2008) Characterization of the proteasome interaction network using a QTAX-based tag-team strategy and protein interaction network analysis. Proc. Natl. Acad. Sci. U. S. A. 105, 13333-13338
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 13333-13338
-
-
Guerrero, C.1
Milenkovic, T.2
Przulj, N.3
Kaiser, P.4
Huang, L.5
-
50
-
-
0033791447
-
Proteasomal proteomics. Identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes
-
Verma, R., Chen, S., Feldman, R., Schieltz, D., Yates, J., Dohmen, J., and Deshaies, R. J. (2000) Proteasomal proteomics. Identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol. Biol. Cell 11, 3425-3439
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 3425-3439
-
-
Verma, R.1
Chen, S.2
Feldman, R.3
Schieltz, D.4
Yates, J.5
Dohmen, J.6
Deshaies, R.J.7
-
51
-
-
0033618256
-
Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast
-
Russell, S. J., Steger, K. A., and Johnston, S. A. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J. Biol. Chem. 274, 21943-21952
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21943-21952
-
-
Russell, S.J.1
Steger, K.A.2
Johnston, S.A.3
-
52
-
-
0142215475
-
Global analysis of protein expression in yeast
-
Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., and Weissman, J. S. (2003) Global analysis of protein expression in yeast. Nature 425, 737-741
-
(2003)
Nature
, vol.425
, pp. 737-741
-
-
Ghaemmaghami, S.1
Huh, W.K.2
Bower, K.3
Howson, R.W.4
Belle, A.5
Dephoure, N.6
O'Shea, E.K.7
Weissman, J.S.8
-
53
-
-
0037438021
-
Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK293 cells
-
Kirkpatrick, D. S., Dale, K. V., Catania, J. M., and Gandolfi, A. J. (2003) Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK293 cells. Toxicol. Appl. Pharmacol. 186, 101-109
-
(2003)
Toxicol. Appl. Pharmacol.
, vol.186
, pp. 101-109
-
-
Kirkpatrick, D.S.1
Dale, K.V.2
Catania, J.M.3
Gandolfi, A.J.4
-
54
-
-
18944372150
-
Integrating phenotypic and expression profiles to map arsenic-response networks
-
Haugen, A. C, Kelley, R., Collins, J. B., Tucker, C J., Deng, C, Afshari, C. A., Brown, J. M., Ideker, T., and Van Houten, B. (2004) Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol. 5, R95
-
(2004)
Genome Biol.
, vol.5
-
-
Haugen, A.C.1
Kelley, R.2
Collins, J.B.3
Tucker, C.J.4
Deng, C.5
Afshari, C.A.6
Brown, J.M.7
Ideker, T.8
Van Houten, B.9
-
55
-
-
80052212289
-
Stalled proteasomes are directly relieved by P97 recruitment
-
Isakov, E., and Stanhill, A. (2011) Stalled proteasomes are directly relieved by P97 recruitment. J. Biol. Chem. 286, 30274-30283
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 30274-30283
-
-
Isakov, E.1
Stanhill, A.2
-
56
-
-
58549108805
-
Rhomboid proteases and their biological functions
-
Freeman, M. (2008) Rhomboid proteases and their biological functions. Annu. Rev. Genet. 42, 191-210
-
(2008)
Annu. Rev. Genet.
, vol.42
, pp. 191-210
-
-
Freeman, M.1
-
57
-
-
79953269767
-
Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling
-
Zettl, M., Adrain, C, Strisovsky, K., Lastun, V., and Freeman, M. (2011) Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling. Cell 145, 79-91
-
(2011)
Cell
, vol.145
, pp. 79-91
-
-
Zettl, M.1
Adrain, C.2
Strisovsky, K.3
Lastun, V.4
Freeman, M.5
-
58
-
-
80455164551
-
Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant a-1 antitrypsin from the endoplasmic reticulum
-
Greenblatt, E. J., Olzmann, J. A., and Kopito, R. R. (2011) Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant a-1 antitrypsin from the endoplasmic reticulum. Nat. Struct. Mol. Biol. 18, 1147-1152
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 1147-1152
-
-
Greenblatt, E.J.1
Olzmann, J.A.2
Kopito, R.R.3
-
59
-
-
45449098051
-
A20/AN1 zinc-finger domain-containing proteins in plants and animals represent common elements in stress response
-
Vij, S., and Tyagi, A. K. (2008) A20/AN1 zinc-finger domain-containing proteins in plants and animals represent common elements in stress response. Funct. Integr. Genomics 8, 301-307
-
(2008)
Funct. Integr. Genomics
, vol.8
, pp. 301-307
-
-
Vij, S.1
Tyagi, A.K.2
-
60
-
-
1942501590
-
Overexpression of a zinc-finger protein gene from rice confers tolerance to cold, dehydration, and salt stress in transgenic tobacco
-
Mukhopadhyay, A., Vij, S., and Tyagi, A. K. (2004) Overexpression of a zinc-finger protein gene from rice confers tolerance to cold, dehydration, and salt stress in transgenic tobacco. Proc. Natl. Acad. Sci. U. S. A. 101, 6309-6314
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 6309-6314
-
-
Mukhopadhyay, A.1
Vij, S.2
Tyagi, A.K.3
-
61
-
-
11844251985
-
A20 inhibits NF-κB activation by dual ubiquitin-editing functions
-
Heyninck, K., and Beyaert, R. (2005) A20 inhibits NF-κB activation by dual ubiquitin-editing functions. Trends Biochem. Sci. 30, 1-4
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 1-4
-
-
Heyninck, K.1
Beyaert, R.2
-
62
-
-
1942425971
-
ZNF216 is an A20-like and IκB kinase 7-interacting inhibitor of NFκB activation
-
Huang, J., Teng, L., Li, L., Liu, T., Li, L., Chen, D., Xu, L. G., Zhai, Z., and Shu, H. B. (2004) ZNF216 is an A20-like and IκB kinase 7-interacting inhibitor of NFκB activation. J. Biol. Chem. 279, 16847-16853
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16847-16853
-
-
Huang, J.1
Teng, L.2
Li, L.3
Liu, T.4
Li, L.5
Chen, D.6
Xu, L.G.7
Zhai, Z.8
Shu, H.B.9
-
63
-
-
67650240053
-
Ubx4 modulates cdc48 activity and influences degradation of misfolded proteins of the endoplasmic reticulum
-
Alberts, S. M., Sonntag, C, Schäfer, A., and Wolf, D. H. (2009) Ubx4 modulates cdc48 activity and influences degradation of misfolded proteins of the endoplasmic reticulum. J. Biol. Chem. 284, 16082-16089
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16082-16089
-
-
Alberts, S.M.1
Sonntag, C.2
Schäfer, A.3
Wolf, D.H.4
-
64
-
-
27144539523
-
Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation
-
Schuberth, C, and Buchberger, A. (2005) Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation. Nat Cell Biol. 7, 999-1006
-
(2005)
Nat Cell Biol.
, vol.7
, pp. 999-1006
-
-
Schuberth, C.1
Buchberger, A.2
-
65
-
-
30744451400
-
Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone
-
Rumpf, S., and Jentsch, S. (2006) Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone. Mol. Cell 21, 261-269
-
(2006)
Mol. Cell
, vol.21
, pp. 261-269
-
-
Rumpf, S.1
Jentsch, S.2
-
66
-
-
0142184341
-
Global analysis of protein localization in budding yeast
-
Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., and O'Shea, E. K. (2003) Global analysis of protein localization in budding yeast. Nature 425, 686-691
-
(2003)
Nature
, vol.425
, pp. 686-691
-
-
Huh, W.K.1
Falvo, J.V.2
Gerke, L.C.3
Carroll, A.S.4
Howson, R.W.5
Weissman, J.S.6
O'Shea, E.K.7
-
67
-
-
84870704332
-
ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain
-
Chia, W. S., Chia, D. X., Rao, F., Bar Nun, S., and Geifman Shochat, S. (2012) ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain. PLoS One 7, e50490
-
(2012)
PLoS One
, vol.7
-
-
Chia, W.S.1
Chia, D.X.2
Rao, F.3
Bar Nun, S.4
Geifman Shochat, S.5
-
68
-
-
80051998695
-
The Cdc48 ATPase modulates the interaction between two proteolytic factors Ufd2 and Rad23
-
Baek, G. H., Kim, I., and Rao, H. (2011) The Cdc48 ATPase modulates the interaction between two proteolytic factors Ufd2 and Rad23. Proc. Natl. Acad. Sci. U. S. A. 108, 13558-13563
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 13558-13563
-
-
Baek, G.H.1
Kim, I.2
Rao, H.3
-
69
-
-
33746985070
-
Sel1p/Ubx2p participates in a distinct Cdc48p-dependent endoplasmic reticulum-associated degradation pathway
-
Wilson, J. D., Liu, Y., Bentivoglio, C. M., and Barlowe, C. (2006) Sel1p/Ubx2p participates in a distinct Cdc48p-dependent endoplasmic reticulum-associated degradation pathway. Traffic 7, 1213-1223
-
(2006)
Traffic
, vol.7
, pp. 1213-1223
-
-
Wilson, J.D.1
Liu, Y.2
Bentivoglio, C.M.3
Barlowe, C.4
-
70
-
-
84874452437
-
Bipartite determinants mediate an evolutionarily conserved interaction between Cdc48 and the 20S peptidase
-
Barthelme, D., and Sauer, R. T. (2013) Bipartite determinants mediate an evolutionarily conserved interaction between Cdc48 and the 20S peptidase. Proc. Natl. Acad. Sci. U. S. A. 110, 3327-3332
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 3327-3332
-
-
Barthelme, D.1
Sauer, R.T.2
-
71
-
-
4444284299
-
Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation
-
Schuberth, C, Richly, H, Rumpf, S., and Buchberger, A. (2004) Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation. EMBORep. 5, 818-824
-
(2004)
EMBORep.
, vol.5
, pp. 818-824
-
-
Schuberth, C.1
Richly, H.2
Rumpf, S.3
Buchberger, A.4
-
72
-
-
0038036801
-
Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4
-
Wang, B., Alam, S. L., Meyer, H. H., Payne, M., Stemmler, T. L., Davis, D. R., and Sundquist, W. I. (2003) Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4. J. Biol. Chem. 278, 20225-20234
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20225-20234
-
-
Wang, B.1
Alam, S.L.2
Meyer, H.H.3
Payne, M.4
Stemmler, T.L.5
Davis, D.R.6
Sundquist, W.I.7
-
73
-
-
0038487228
-
Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol. Dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains
-
Ye, Y., Meyer, H. H., and Rapoport, T. A. (2003) Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol. Dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J. Cell Biol. 162, 71-84
-
(2003)
J. Cell Biol.
, vol.162
, pp. 71-84
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
|