Retinitis pigmentosa mutants provide insight into the role of the N-terminal cap in rhodopsin folding, structure, and function

Journal of Biological Chemistry

Volumn 288, Issue 47, 2013, Pages 33912-33926

  Opefi, Chikwado A ^a   South, Kieron ^a   Reynolds, Christopher A ^a   Smith, Steven O ^b   Reeves, Philip J ^a  

^a UNIVERSITY OF ESSEX   (United Kingdom)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOSOMAL DOMINANT RETINITIS PIGMENTOSA; DISULFIDE BONDS; ENHANCED STABILITY; EXTRACELLULAR LOOPS; G PROTEIN ACTIVATION; GAIN INSIGHT; MAMMALIAN CELLS; RETINITIS PIGMENTOSA;

AMINO ACIDS; BIOCHEMISTRY; COVALENT BONDS; PHOTOBLEACHING; RESTORATION; SIGNAL TRANSDUCTION;

PROTEINS;

CHAPERONE; DISULFIDE; G PROTEIN COUPLED RECEPTOR; MUTANT PROTEIN; RHODOPSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEACHING; CONTROLLED STUDY; DISULFIDE BOND; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; RETINITIS PIGMENTOSA; SIGNAL TRANSDUCTION;

G-PROTEIN-COUPLED RECEPTOR (GPCR); MEMBRANE PROTEINS; PHOTOTRANSDUCTION; PROTEIN MISFOLDING; PROTEIN STABILITY; RETINAL DEGENERATION; RETINOID; RHODOPSIN;

AMINO ACID SUBSTITUTION; ANIMALS; CATTLE; HEK293 CELLS; HUMANS; MUTATION, MISSENSE; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RETINALDEHYDE; RETINITIS PIGMENTOSA; RHODOPSIN;

EID: 84888309942     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.483032     Document Type: Article

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