A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice

Gastroenterology

Volumn 145, Issue 6, 2013, Pages 1449-1458

  Philip, Bincy ^a   Roland, Christina L ^a   Daniluk, Jaroslaw ^b   Liu, Yan ^a   Chatterjee, Deyali ^a   Gomez, Sobeyda B ^a   Ji, Baoan ^c   Huang, Haojie ^a   Wang, Huamin ^a   Fleming, Jason B ^a   Logsdon, Craig D ^a   Cruz Monserrate, Zobeida ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^c MAYO CLINIC   (United States)

Author keywords

Oncogene; Pancreatic Cancer; Prostaglandin; Signal Transduction

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR;

ACINAR CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; CYCLOOXYGENASE 2 GENE; CYSTIC FIBROSIS; GENE ACTIVATION; LIPID DIET; MOUSE; NONHUMAN; OBESITY; ONCOGENE; ONCOGENE K RAS; PANCREAS ADENOCARCINOMA; PANCREAS ADENOMA; PANCREATITIS; PRIORITY JOURNAL; SURVIVAL TIME; TUMOR GROWTH; UPREGULATION;

EID: 84888267890     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.08.018     Document Type: Article

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