메뉴 건너뛰기




Volumn 122, Issue 22, 2013, Pages 3642-3650

Platelet-derived ERp57 mediates platelet incorporation into a growing thrombus by regulation of the αIIbβ3 integrin

Author keywords

[No Author keywords available]

Indexed keywords

ALEXA 488; ALPHA2BETA3 INTEGRIN; ERP57 PROTEIN; FLUORESCENT DYE; INTEGRIN; MANGANESE; MUTANT PROTEIN; PROTEIN DISULFIDE ISOMERASE; THROMBIN; UNCLASSIFIED DRUG; FIBRINOGEN RECEPTOR; PDIA3 PROTEIN, HUMAN; PDIA3 PROTEIN, MOUSE; RECOMBINANT PROTEIN;

EID: 84888229791     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-06-506691     Document Type: Article
Times cited : (83)

References (48)
  • 1
    • 71549132149 scopus 로고    scopus 로고
    • Protein disulfide isomerase: A critical evaluation of its function in disulfide bond formation
    • Hatahet F, Ruddock LW. Protein disulfide isomerase: a critical evaluation of its function in disulfide bond formation. Antioxid Redox Signal. 2009;11(11):2807-2850.
    • (2009) Antioxid Redox Signal , vol.11 , Issue.11 , pp. 2807-2850
    • Hatahet, F.1    Ruddock, L.W.2
  • 2
    • 64549119138 scopus 로고    scopus 로고
    • Redox control of platelet function
    • Essex DW. Redox control of platelet function. Antioxid Redox Signal. 2009;11(5):1191-1225.
    • (2009) Antioxid Redox Signal , vol.11 , Issue.5 , pp. 1191-1225
    • Essex, D.W.1
  • 3
    • 0032985071 scopus 로고    scopus 로고
    • Protein disulphide isomerase mediates platelet aggregation and secretion
    • Essex DW, Li M. Protein disulphide isomerase mediates platelet aggregation and secretion. Br J Haematol. 1999;104(3):448-454.
    • (1999) Br J Haematol. , vol.104 , Issue.3 , pp. 448-454
    • Essex, D.W.1    Li, M.2
  • 4
    • 0034674762 scopus 로고    scopus 로고
    • Protein disulfide isomerase mediates integrin-dependent adhesion
    • Lahav J, Gofer-Dadosh N, Luboshitz J, Hess O, Shaklai M. Protein disulfide isomerase mediates integrin-dependent adhesion. FEBS Lett. 2000; 475(2):89-92.
    • (2000) FEBS Lett. , vol.475 , Issue.2 , pp. 89-92
    • Lahav, J.1    Gofer-Dadosh, N.2    Luboshitz, J.3    Hess, O.4    Shaklai, M.5
  • 5
    • 0036786353 scopus 로고    scopus 로고
    • Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange
    • Lahav J, Jurk K, Hess O, et al. Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange. Blood. 2002;100(7): 2472-2478.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2472-2478
    • Lahav, J.1    Jurk, K.2    Hess, O.3
  • 6
    • 0141567629 scopus 로고    scopus 로고
    • Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1
    • Lahav J, Wijnen EM, Hess O, et al. Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1. Blood. 2003;102(6): 2085-2092.
    • (2003) Blood , vol.102 , Issue.6 , pp. 2085-2092
    • Lahav, J.1    Wijnen, E.M.2    Hess, O.3
  • 7
    • 4544381890 scopus 로고    scopus 로고
    • Platelet cell-surface protein disulphide-isomerase mediated Snitrosoglutathione consumption
    • Root P, Sliskovic I, Mutus B. Platelet cell-surface protein disulphide-isomerase mediated Snitrosoglutathione consumption. Biochem J. 2004; 382(Pt 2):575-580.
    • (2004) Biochem J. , vol.382 , pp. 575-580
    • Root, P.1    Sliskovic, I.2    Mutus, B.3
  • 8
    • 13544260505 scopus 로고    scopus 로고
    • A role for the thiol isomerase protein ERP5 in platelet function
    • Jordan PA, Stevens JM, Hubbard GP, et al. A role for the thiol isomerase protein ERP5 in platelet function. Blood. 2005;105(4):1500-1507.
    • (2005) Blood , vol.105 , Issue.4 , pp. 1500-1507
    • Jordan, P.A.1    Stevens, J.M.2    Hubbard, G.P.3
  • 9
    • 40549084318 scopus 로고    scopus 로고
    • A critical role for extracellular protein disulfide isomerase during thrombus formation in mice
    • Cho J, Furie BC, Coughlin SR, Furie B. A critical role for extracellular protein disulfide isomerase during thrombus formation in mice. J Clin Invest. 2008;118(3):1123-1131.
    • (2008) J Clin Invest. , vol.118 , Issue.3 , pp. 1123-1131
    • Cho, J.1    Furie, B.C.2    Coughlin, S.R.3    Furie, B.4
  • 10
    • 40549121595 scopus 로고    scopus 로고
    • Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation
    • Reinhardt C, von Brühl ML, Manukyan D, et al. Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation. J Clin Invest. 2008; 118(3):1110-1122.
    • (2008) J Clin Invest. , vol.118 , Issue.3 , pp. 1110-1122
    • Reinhardt, C.1    Von Brühl, M.L.2    Manukyan, D.3
  • 12
    • 84863139700 scopus 로고    scopus 로고
    • The disulfide isomerase ERp57 mediates platelet aggregation, hemostasis, and thrombosis
    • Wu Y, Ahmad SS, Zhou J, Wang L, Cully MP, Essex DW. The disulfide isomerase ERp57 mediates platelet aggregation, hemostasis, and thrombosis. Blood. 2012;119(7):1737-1746.
    • (2012) Blood , vol.119 , Issue.7 , pp. 1737-1746
    • Wu, Y.1    Ahmad, S.S.2    Zhou, J.3    Wang, L.4    Cully, M.P.5    Essex, D.W.6
  • 13
    • 78649466923 scopus 로고    scopus 로고
    • Endotheliumderived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo
    • Jasuja R, Furie B, Furie BC. Endotheliumderived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo. Blood. 2010;116(22):4665-4674.
    • (2010) Blood , vol.116 , Issue.22 , pp. 4665-4674
    • Jasuja, R.1    Furie, B.2    Furie, B.C.3
  • 14
    • 84886930949 scopus 로고    scopus 로고
    • Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice
    • Kim K, Hahm E, Li J, et al. Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice. Blood. 2013;122(6):1052-1061.
    • (2013) Blood , vol.122 , Issue.6 , pp. 1052-1061
    • Kim, K.1    Hahm, E.2    Li, J.3
  • 15
    • 77953809347 scopus 로고    scopus 로고
    • ERp57, a multifunctional endoplasmic reticulum resident oxidoreductase
    • Coe H, Michalak M. ERp57, a multifunctional endoplasmic reticulum resident oxidoreductase. Int J Biochem Cell Biol. 2010;42(6):796-799.
    • (2010) Int J Biochem Cell Biol. , vol.42 , Issue.6 , pp. 796-799
    • Coe, H.1    Michalak, M.2
  • 17
    • 63449127686 scopus 로고    scopus 로고
    • G-proteincoupled receptors as signaling targets for antiplatelet therapy
    • Smyth SS, Woulfe DS, Weitz JI, et al; 2008 Platelet Colloquium Participants. G-proteincoupled receptors as signaling targets for antiplatelet therapy. Arterioscler Thromb Vasc Biol. 2009;29(4):449-457.
    • (2009) Arterioscler Thromb Vasc Biol. , vol.29 , Issue.4 , pp. 449-457
    • Smyth, S.S.1    Woulfe, D.S.2    Weitz, J.I.3
  • 18
    • 77949862490 scopus 로고    scopus 로고
    • The final steps of integrin activation: The end game
    • Shattil SJ, Kim C, Ginsberg MH. The final steps of integrin activation: the end game. Nat Rev Mol Cell Biol. 2010;11(4):288-300.
    • (2010) Nat Rev Mol Cell Biol. , vol.11 , Issue.4 , pp. 288-300
    • Shattil, S.J.1    Kim, C.2    Ginsberg, M.H.3
  • 19
    • 29244474572 scopus 로고    scopus 로고
    • Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57
    • Garbi N, Tanaka S, Momburg F, Hämmerling GJ. Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57. Nat Immunol. 2006;7(1):93-102.
    • (2006) Nat Immunol. , vol.7 , Issue.1 , pp. 93-102
    • Garbi, N.1    Tanaka, S.2    Momburg, F.3    Hämmerling, G.J.4
  • 20
    • 33846911975 scopus 로고    scopus 로고
    • Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo
    • Tiedt R, Schomber T, Hao-Shen H, Skoda RC. Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo. Blood. 2007;109(4):1503-1506.
    • (2007) Blood , vol.109 , Issue.4 , pp. 1503-1506
    • Tiedt, R.1    Schomber, T.2    Hao-Shen, H.3    Skoda, R.C.4
  • 21
    • 0032590042 scopus 로고    scopus 로고
    • Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival
    • Hodivala-Dilke KM, McHugh KP, Tsakiris DA, et al. Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. J Clin Invest. 1999; 103(2):229-238.
    • (1999) J Clin Invest. , vol.103 , Issue.2 , pp. 229-238
    • Hodivala-Dilke, K.M.1    McHugh, K.P.2    Tsakiris, D.A.3
  • 22
    • 32444439995 scopus 로고    scopus 로고
    • Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt
    • Mukai Y, Rikitake Y, Shiojima I, et al. Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt. J Clin Invest. 2006;116(2):334-343.
    • (2006) J Clin Invest. , vol.116 , Issue.2 , pp. 334-343
    • Mukai, Y.1    Rikitake, Y.2    Shiojima, I.3
  • 23
    • 0035877994 scopus 로고    scopus 로고
    • Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling
    • Wu Y, Suzuki-Inoue K, Satoh K, et al. Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling. Blood. 2001;97(12): 3836-3845.
    • (2001) Blood , vol.97 , Issue.12 , pp. 3836-3845
    • Wu, Y.1    Suzuki-Inoue, K.2    Satoh, K.3
  • 24
    • 0038542920 scopus 로고    scopus 로고
    • Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: Role of phosphoinositide 3-kinase
    • Wu Y, Asazuma N, Satoh K, et al. Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase. Blood. 2003;101(9): 3469-3476.
    • (2003) Blood , vol.101 , Issue.9 , pp. 3469-3476
    • Wu, Y.1    Asazuma, N.2    Satoh, K.3
  • 25
    • 0035918587 scopus 로고    scopus 로고
    • Protein disulfide isomerase and sulfhydryl-dependent pathways in platelet activation
    • Essex DW, Li M, Miller A, Feinman RD. Protein disulfide isomerase and sulfhydryl-dependent pathways in platelet activation. Biochemistry. 2001;40(20):6070-6075.
    • (2001) Biochemistry , vol.40 , Issue.20 , pp. 6070-6075
    • Essex, D.W.1    Li, M.2    Miller, A.3    Feinman, R.D.4
  • 26
    • 34249903638 scopus 로고    scopus 로고
    • Characterization of redox state and reductase activity of protein disulfide isomerase under different redox environments using a sensitive fluorescent assay
    • Raturi A, Mutus B. Characterization of redox state and reductase activity of protein disulfide isomerase under different redox environments using a sensitive fluorescent assay. Free Radic Biol Med. 2007;43(1):62-70.
    • (2007) Free Radic Biol Med. , vol.43 , Issue.1 , pp. 62-70
    • Raturi, A.1    Mutus, B.2
  • 27
    • 84879701801 scopus 로고    scopus 로고
    • Red blood cells mediate the onset of thrombosis in the ferric chloride murine model
    • Barr JD, Chauhan AK, Schaeffer GV, Hansen JK, Motto DG. Red blood cells mediate the onset of thrombosis in the ferric chloride murine model. Blood. 2013;121(18):3733-3741.
    • (2013) Blood , vol.121 , Issue.18 , pp. 3733-3741
    • Barr, J.D.1    Chauhan, A.K.2    Schaeffer, G.V.3    Hansen, J.K.4    Motto, D.G.5
  • 28
    • 78751696504 scopus 로고    scopus 로고
    • The kinetics of αiIbβ3 activation determines the size and stability of thrombi in mice: Implications for antiplatelet therapy
    • Stolla M, Stefanini L, Roden RC, et al. The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy. Blood. 2011;117(3): 1005-1013.
    • (2011) Blood , vol.117 , Issue.3 , pp. 1005-1013
    • Stolla, M.1    Stefanini, L.2    Roden, R.C.3
  • 29
    • 36148955807 scopus 로고    scopus 로고
    • Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion
    • Léon C, Eckly A, Hechler B, et al. Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion. Blood. 2007;110(9):3183-3191.
    • (2007) Blood , vol.110 , Issue.9 , pp. 3183-3191
    • Léon, C.1    Eckly, A.2    Hechler, B.3
  • 30
    • 38349102225 scopus 로고    scopus 로고
    • Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: Studies using a megakaryocyte lineage specific FAK knockout
    • Hitchcock IS, Fox NE, Prévost N, Sear K, Shattil SJ, Kaushansky K. Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout. Blood. 2008;111(2):596-604.
    • (2008) Blood , vol.111 , Issue.2 , pp. 596-604
    • Hitchcock, I.S.1    Fox, N.E.2    Prévost, N.3    Sear, K.4    Shattil, S.J.5    Kaushansky, K.6
  • 32
    • 37549064277 scopus 로고    scopus 로고
    • Talin is required for integrin-mediated platelet function in hemostasis and thrombosis
    • Petrich BG, Marchese P, Ruggeri ZM, et al. Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med. 2007; 204(13):3103-3111.
    • (2007) J Exp Med. , vol.204 , Issue.13 , pp. 3103-3111
    • Petrich, B.G.1    Marchese, P.2    Ruggeri, Z.M.3
  • 33
    • 33646594461 scopus 로고    scopus 로고
    • Consequences of ERp57 deletion on oxidative folding of obligate and facultative clients of the calnexin cycle
    • Soldà T, Garbi N, Hämmerling GJ, Molinari M. Consequences of ERp57 deletion on oxidative folding of obligate and facultative clients of the calnexin cycle. J Biol Chem. 2006;281(10): 6219-6226.
    • (2006) J Biol Chem. , vol.281 , Issue.10 , pp. 6219-6226
    • Soldà, T.1    Garbi, N.2    Hämmerling, G.J.3    Molinari, M.4
  • 34
    • 84920285926 scopus 로고    scopus 로고
    • Endothelium but not platelet derived thiol isomerase ERp57 is required for thrombosis in vivo
    • Jasuja R, Sharda AV, Kim SH, Furie B, Furie BC. Endothelium but not platelet derived thiol isomerase ERp57 is required for thrombosis in vivo. J Thromb Haemost. 2013;11(suppl 2):202.
    • (2013) J Thromb Haemost. , vol.11 , pp. 202
    • Jasuja, R.1    Sharda, A.V.2    Kim, S.H.3    Furie, B.4    Furie, B.C.5
  • 35
    • 77956903176 scopus 로고    scopus 로고
    • Naturally occurring free thiols within beta 2-glycoprotein I in vivo: Nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress-induced cell injury
    • Ioannou Y, Zhang JY, Passam FH, et al. Naturally occurring free thiols within beta 2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress-induced cell injury. Blood. 2010;116(11): 1961-1970.
    • (2010) Blood , vol.116 , Issue.11 , pp. 1961-1970
    • Ioannou, Y.1    Zhang, J.Y.2    Passam, F.H.3
  • 36
    • 0032506098 scopus 로고    scopus 로고
    • Exposure of the cryptic Arg-Gly-Asp sequence in thrombospondin-1 by protein disulfide isomerase
    • Hotchkiss KA, Matthias LJ, Hogg PJ. Exposure of the cryptic Arg-Gly-Asp sequence in thrombospondin-1 by protein disulfide isomerase. Biochim Biophys Acta. 1998;1388(2):478-488.
    • (1998) Biochim Biophys Acta. , vol.1388 , Issue.2 , pp. 478-488
    • Hotchkiss, K.A.1    Matthias, L.J.2    Hogg, P.J.3
  • 37
    • 77956906154 scopus 로고    scopus 로고
    • Endothelial cell thiol isomerase: Potential role in thrombus formation [abstract]
    • Abstract 3709
    • Jasuja R, Furie B, Furie BC. Endothelial cell thiol isomerase: potential role in thrombus formation [abstract]. Blood. 2007;110(111). Abstract 3709.
    • (2007) Blood , vol.110 , Issue.111
    • Jasuja, R.1    Furie, B.2    Furie, B.C.3
  • 38
    • 10244224019 scopus 로고    scopus 로고
    • Functional and structural correlations of individual alphaIIbbeta3 molecules
    • Litvinov RI, Nagaswami C, Vilaire G, Shuman H, Bennett JS, Weisel JW. Functional and structural correlations of individual alphaIIbbeta3 molecules. Blood. 2004;104(13):3979-3985.
    • (2004) Blood , vol.104 , Issue.13 , pp. 3979-3985
    • Litvinov, R.I.1    Nagaswami, C.2    Vilaire, G.3    Shuman, H.4    Bennett, J.S.5    Weisel, J.W.6
  • 39
    • 8544259562 scopus 로고    scopus 로고
    • Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics
    • Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 2004;432(7013):59-67.
    • (2004) Nature , vol.432 , Issue.7013 , pp. 59-67
    • Xiao, T.1    Takagi, J.2    Coller, B.S.3    Wang, J.H.4    Springer, T.A.5
  • 40
    • 75149147568 scopus 로고    scopus 로고
    • Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation
    • Holbrook LM, Watkins NA, Simmonds AD, Jones CI, Ouwehand WH, Gibbins JM. Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation. Br J Haematol. 2010;148(4):627-637.
    • (2010) Br J Haematol. , vol.148 , Issue.4 , pp. 627-637
    • Holbrook, L.M.1    Watkins, N.A.2    Simmonds, A.D.3    Jones, C.I.4    Ouwehand, W.H.5    Gibbins, J.M.6
  • 41
    • 0018547288 scopus 로고
    • Exposure of platelet fibrinogen receptors by ADP and epinephrine
    • Bennett JS, Vilaire G. Exposure of platelet fibrinogen receptors by ADP and epinephrine. J Clin Invest. 1979;64(5):1393-1401.
    • (1979) J Clin Invest. , vol.64 , Issue.5 , pp. 1393-1401
    • Bennett, J.S.1    Vilaire, G.2
  • 42
    • 55749091808 scopus 로고    scopus 로고
    • Platelet microparticle-associated protein disulfide isomerase promotes platelet aggregation and inactivates insulin
    • Raturi A, Miersch S, Hudson JW, Mutus B. Platelet microparticle-associated protein disulfide isomerase promotes platelet aggregation and inactivates insulin. Biochim Biophys Acta. 2008; 1778(12):2790-2796.
    • (2008) Biochim Biophys Acta. , vol.1778 , Issue.12 , pp. 2790-2796
    • Raturi, A.1    Miersch, S.2    Hudson, J.W.3    Mutus, B.4
  • 43
    • 80055109602 scopus 로고    scopus 로고
    • Extracellular protein disulfide isomerase regulates feedback activation of platelet thrombin generation via modulation of coagulation factor binding
    • Jurk K, Lahav J, VAN Aken H, Brodde MF, Nofer JR, Kehrel BE. Extracellular protein disulfide isomerase regulates feedback activation of platelet thrombin generation via modulation of coagulation factor binding. J Thromb Haemost. 2011;9(11):2278-2290.
    • (2011) J Thromb Haemost. , vol.9 , Issue.11 , pp. 2278-2290
    • Jurk, K.1    Lahav, J.2    Van Aken, H.3    Brodde, M.F.4    Nofer, J.R.5    Kehrel, B.E.6
  • 44
    • 0034629281 scopus 로고    scopus 로고
    • Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3)
    • Yan B, Hu DD, Knowles SK, Smith JW. Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3). J Biol Chem. 2000;275(10): 7249-7260.
    • (2000) J Biol Chem. , vol.275 , Issue.10 , pp. 7249-7260
    • Yan, B.1    Hu, D.D.2    Knowles, S.K.3    Smith, J.W.4
  • 45
  • 46
    • 1642504824 scopus 로고    scopus 로고
    • Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit
    • Kamata T, Ambo H, Puzon-McLaughlin W, et al. Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit. Biochem J. 2004;378(Pt 3):1079-1082.
    • (2004) Biochem J. , vol.378 , pp. 1079-1082
    • Kamata, T.1    Ambo, H.2    Puzon-McLaughlin, W.3
  • 47
    • 50349098094 scopus 로고    scopus 로고
    • Specific cysteines in beta3 are involved in disulfide bond exchange-dependent and -independent activation of alphaIIbbeta3
    • Mor-Cohen R, Rosenberg N, Landau M, Lahav J, Seligsohn U. Specific cysteines in beta3 are involved in disulfide bond exchange-dependent and -independent activation of alphaIIbbeta3. J Biol Chem. 2008;283(28):19235-19244.
    • (2008) J Biol Chem. , vol.283 , Issue.28 , pp. 19235-19244
    • Mor-Cohen, R.1    Rosenberg, N.2    Landau, M.3    Lahav, J.4    Seligsohn, U.5
  • 48
    • 84858606733 scopus 로고    scopus 로고
    • Unique disulfide bonds in epidermal growth factor (EGF) domains of β3 affect structure and function of αiIbβ3 and αvβ3 integrins in different manner
    • Mor-Cohen R, Rosenberg N, Einav Y, et al. Unique disulfide bonds in epidermal growth factor (EGF) domains of β3 affect structure and function of αIIbβ3 and αvβ3 integrins in different manner. J Biol Chem. 2012;287(12):8879-8891.
    • (2012) J Biol Chem. , vol.287 , Issue.12 , pp. 8879-8891
    • Mor-Cohen, R.1    Rosenberg, N.2    Einav, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.