Platelet microparticle-associated protein disulfide isomerase promotes platelet aggregation and inactivates insulin

Biochimica et Biophysica Acta - Biomembranes

Volumn 1778, Issue 12, 2008, Pages 2790-2796

  Raturi, Arun ^a   Miersch, Shane ^b   Hudson, John W ^c   Mutus, Bulent ^c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF WINDSOR   (Canada)

Author keywords

Microparticle; Platelet; Pro coagulant activity; Protein disulfide isomerase; Type II diabetes

Indexed keywords

INSULIN; PROCOAGULANT; PROTEIN DISULFIDE ISOMERASE; PROTEIN KINASE B;

ADULT; AGED; ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOLOGY; INSULIN DEGRADATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PLATELET MICROPARTICLE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; THROMBOCYTE AGGREGATION;

ADULT; AGED; BIOLOGICAL PROCESSES; BLOOD PLATELETS; DIABETES MELLITUS, TYPE 2; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MIDDLE AGED; PARTICLE SIZE; PLATELET AGGREGATION; PROTEIN DISULFIDE-ISOMERASES; TIME FACTORS;

EID: 55749091808     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2008.07.003     Document Type: Article

References (39)

1. Goldberger R.F., Epstein C.J., and Anfinsen C.B. Acceleration of reactivation of reduced bovine pancreatic ribonuclease by a microsomal system from rat liver. J. Biol. Chem. 238 (1963) 628
2. Wilkinson B., and Gilbert H.F. Protein disulfide isomerase. Biochim. Biophys. Acta 1699 (2004) 35
3. Turano C., Coppari S., Altieri F., and Ferraro A. Proteins of the PDI family: unpredicted non-ER locations and functions. J. Cell Physiol. 193 (2002) 154
4. Terada K., Manchikalapudi P., Noiva R., Jauregui H.O., Stockert R.J., and Schilsky M.L. Secretion, surface localization, turnover, and steady state expression of protein disulfide isomerase in rat hepatocytes. J. Biol. Chem. 270 (1995) 20410
5. Essex D.W., Chen K., and Swiatkowska M. Localization of protein disulfide isomerase to the external surface of the platelet plasma membrane. Blood 86 (1995) 2168
6. Essex D.W., and Li M. Protein disulphide isomerase mediates platelet aggregation and secretion. Br. J. Haematol. 104 (1999) 448
7. Lahav J., Jurk K., Hess O., Barnes M.J., Farndale R.W., Luboshitz J., and Kehrel B.E. Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange. Blood 100 (2002) 2472
8. Raturi A., and Mutus B. Characterization of redox state and reductase activity of protein disulfide isomerase under different redox environments using a sensitive fluorescent assay. Free Radic. Biol. Med. 43 (2007) 62
9. Wolf P. The nature and significance of platelet products in human plasma. Br. J. Haematol. 13 (1967) 269
10. Crawford N. The presence of contractile proteins in platelet microparticles isolated from human and animal platelet-free plasma. Br. J. Haematol. 21 (1971) 53
11. Morel O., Toti F., Hugel B., Bakouboula B., Camoin-Jau L., gnat-George F., and Freyssinet J.M. Procoagulant microparticles: disrupting the vascular homeostasis equation?. Arterioscler. Thromb. Vasc. Biol. 26 (2006) 2594
12. Sinauridze E.I., Kireev D.A., Popenko N.Y., Pichugin A.V., Panteleev M.A., Krymskaya O.V., and Ataullakhanov F.I. Platelet microparticle membranes have 50-to 100-fold higher specific procoagulant activity than activated platelets. Thromb. Haemost. 97 (2007) 425
13. Nomura S., Suzuki M., Katsura K., Xie G.L., Miyazaki Y., Miyake T., Kido H., Kagawa H., and Fukuhara S. Platelet-derived microparticles may influence the development of atherosclerosis in diabetes mellitus. Atherosclerosis 116 (1995) 235
14. Ahamed J., Versteeg H.H., Kerver M., Chen V.M., Mueller B.M., Hogg P.J., and Ruf W. Disulfide isomerization switches tissue factor from coagulation to cell signaling. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 13932
15. Chen V.M., Ahamed J., Versteeg H.H., Berndt M.C., Ruf W., and Hogg P.J. Evidence for activation of tissue factor by an allosteric disulfide bond. Biochemistry 45 (2006) 12020
16. Versteeg H.H., and Ruf W. Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity. J. Biol. Chem. 282 (2007) 25416
17. Lundstrom J., and Holmgren A. Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity. J. Biol. Chem. 265 (1990) 9114
18. Chang L., Chiang S.H., and Saltiel A.R. Insulin signaling and the regulation of glucose transport. Mol. Med. 10 (2004) 65
19. Sen P., Mukherjee S., Ray D., and Raha S. Involvement of the Akt/PKB signaling pathway with disease processes. Mol. Cell Biochem. 253 (2003) 241
20. Whiteman E.L., Cho H., and Birnbaum M.J. Role of Akt/protein kinase B in metabolism. Trends Endocrinol. Metab. 13 (2002) 444
21. Cheng J.Q., Lindsley C.W., Cheng G.Z., Yang H., and Nicosia S.V. The Akt/PKB pathway: molecular target for cancer drug discovery. Oncogene 24 (2005) 7482
22. Meltzer S., Leiter L., Daneman D., Gerstein H.C., Lau D., Ludwig S., Yale J.F., Zinman B., and Lillie D. 1998 clinical practice guidelines for the management of diabetes in Canada. Canadian Diabetes Association. CMAJ. 159 Suppl 8 (1998) S1
23. George J.N., Thoi L.L., McManus L.M., and Reimann T.A. Isolation of human platelet membrane microparticles from plasma and serum. Blood 60 (1982) 834
24. Bode A.P., Orton S.M., Frye M.J., and Udis B.J. Vesiculation of platelets during in vitro aging. Blood 77 (1991) 887
25. Jordan P.A., Stevens J.M., Hubbard G.P., Barrett N.E., Sage T., Authi K.S., and Gibbins J.M. A role for the thiol isomerase protein ERP5 in platelet function. Blood 105 (2005) 1500
26. Diamant M., Tushuizen M.E., Sturk A., and Nieuwland R. Cellular microparticles: new players in the field of vascular disease?. Eur. J. Clin. Invest. 34 (2004) 392
27. Berckmans R.J., Neiuwland R., Boing A.N., Romijn F.P., Hack C.E., and Sturk A. Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation. Thromb. Haemost. 85 (2001) 639
28. Nomura S. Function and clinical significance of platelet-derived microparticles. Int. J. Hematol. 74 (2001) 397
29. Koga H., Sugiyama S., Kugiyama K., Fukushima H., Watanabe K., Sakamoto T., Yoshimura M., Jinnouchi H., and Ogawa H. Elevated levels of remnant lipoproteins are associated with plasma platelet microparticles in patients with type-2 diabetes mellitus without obstructive coronary artery disease. Eur. Heart J. 27 (2006) 817
30. Castaman G., Yu-Feng L., Battistin E., and Rodeghiero F. Characterization of a novel bleeding disorder with isolated prolonged bleeding time and deficiency of platelet microvesicle generation. Br. J. Haematol. 96 (1997) 458
31. Toti F., Satta N., Fressinaud E., Meyer D., and Freyssinet J.M. Scott syndrome, characterized by impaired transmembrane migration of procoagulant phosphatidylserine and hemorrhagic complications, is an inherited disorder. Blood 87 (1996) 1409
32. Khan I., Zucker-Franklin D., and Karpatkin S. Microthrombocytosis and platelet fragmentation associated with idiopathic/autoimmune thrombocytopenic purpura. Br. J. Haematol. 31 (1975) 449
33. VanWijk M.J., VanBavel E., Sturk A., and Nieuwland R. Microparticles in cardiovascular diseases. Cardiovasc. Res. 59 (2003) 277
34. Diamant M., Nieuwland R., Pablo R.F., Sturk A., Smit J.W., and Radder J.K. Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus. Circulation 106 (2002) 2442
35. Cho J., Furie B.C., Coughlin S.R., and Furie B. A critical role for extracellular protein disulfide isomerase during thrombus formation in mice. J. Clin. Invest. 118 (2008) 1123
36. Reinhardt C., von Bruhl M.L., Manukyan D., Grahl L., Lorenz M., Altmann B., Dlugai S., Hess S., Konrad I., Orschiedt L., Mackman N., Ruddock L., Massberg S., and Engelmann B. Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation. J. Clin. Invest. 118 (2008) 1110
37. Bhattacharya S., Dey D., and Roy S.S. Molecular mechanism of insulin resistance. J. Biosci. 32 (2007) 405
38. Petersen K.F., and Shulman G.I. Etiology of insulin resistance. Am. J. Med. 119 (2006) S10-S16
39. Farris W., Mansourian S., Chang Y., Lindsley L., Eckman E.A., Frosch M.P., Eckman C.B., Tanzi R.E., Selkoe D.J., and Guenette S. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 4162