CD4 blockade directly inhibits mouse and human CD4+ T cell functions independent of Foxp3+ Tregs

Journal of Autoimmunity

Volumn 47, Issue , 2013, Pages 73-82

  Mayer, C T ^a   Huntenburg, J ^a   Nandan, A ^a   Schmitt, E ^b   Czeloth, N ^a   Sparwasser, T ^a  

^a INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Anti CD4; Autoimmunity; DEREG; Foxp3; Tolerance; YTS177.9

Indexed keywords

CD30 LIGAND; CD4 ANTIBODY; CD4 ANTIGEN; DIPHTHERIA TOXIN; INTERLEUKIN 2; OX40 LIGAND; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL FUNCTION; CELL INTERACTION; CELL MATURATION; CHROMOSOME; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HELPER CELL; INTERNALIZATION; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANTI-CD4; AUTOIMMUNITY; DEREG; FOXP3; TOLERANCE; YTS177.9;

ANIMALS; ANTIGENS, CD30; ANTIGENS, CD4; ANTILYMPHOCYTE SERUM; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; DENDRITIC CELLS; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RECEPTORS, OX40; T-LYMPHOCYTES, REGULATORY;

EID: 84888202689     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2013.08.008     Document Type: Article

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