Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses

European Journal of Medicinal Chemistry

Volumn 71, Issue , 2014, Pages 81-90

  Barman, Sanmitra ^a,b   You, Lei ^a,b   Chen, Ran ^a,b   Codrea, Vlad ^a,b   Kago, Grace ^a,b   Edupuganti, Ramakrishna ^a,b   Robertus, Jon ^a,b   Krug, Robert M ^b   Anslyn, Eric V ^a  

^a University of Texas at Austin   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Carbohydrazide; Hemagglutinin; Influenza; Plaque; Real time PCR

Indexed keywords

2 HYDROXY N' (1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL) ETHYLIDENE)BENZOHYDRAZIDE; 3 HYDROXY N [(Z) 1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL)ETHYLIDENEAMINO]NAPHTHALENE 2 CARBOXAMIDE; 3 HYDROXY N' ((5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL) METHYLENE) 2 NAPHTHOHYDRAZIDE; 3 HYDROXY N' (1 (3 HYDROXY 5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL)ETHYLIDENE) 2 NAPHTHOHYDRAZIDE; 3 HYDROXY N' (1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL) BUTYLIDENE) 2 NAPHTHOHYDRAZIDE; 3 HYDROXY N' (1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL) ETHYLIDENE) 2 NAPHTHOHYDRAZIDE; 3 HYDROXY N' (1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL) PROPYLIDENE) 2 NAPHTHOHYDRAZIDE; 3 HYDROXY N' (1 (NAPHTHALENE 2 YL)ETHYLIDENE) 2 NAPHTHOHYDRAZIDE; 3 HYDROXY N' (1 PHENYLETHYLIDENE) 2 NAPHTHOHYDRAZIDE; 3 HYDROXY N' (2 METHYL 1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL)PROPYLIDENE) 2 NAPHTHOHYDRAZIDE; 3 HYDROXY N' (PHENYL(5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL)METHYLENE) 2 NAPHTHOHYDRAZIDE; 6 BROMO 3 HYDROXY N' (1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2YL)ETHYLIDENE) 2 NAPHTHOHYDRAZIDE; HYDRAZIDE DERIVATIVE; N' (1 (2,3 DIHYDRO 1H INDEN 5 YL)ETHYLIDENE) 3 HYDROXY 2 NAPHTHOHYDRAZIDE; N' (1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL)ETHYLIDENE) 2 NAPHTHOHYDRAZIDE; N' (4 (DIMETHYLAMINO) 1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL)BUTYLIDENE) 3 HYDROXY 2 NAPHTHOHYDRAZIDE; N' (4 CHLORO 1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL) BUTYLIDENE) 3 HYDROXY 2 NAPHTHOHYDRAZIDE; N' (CYCLOPENTYL(5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL) METHYLENE) 3 HYDROXY 2 NAPHTHOHYDRAZIDE; N' (CYCLOPROPYL(5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL) METHYLENE) 3 HYDROXY 2 NAPHTHOHYDRAZIDE; N' (CYCLOPROPYL(PHENYL)METHYLENE) 3 HYDROXY 2 NAPHTHOHYDRAZIDE; N' CYCLOHEXYL(5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL) METHYLENE 3 HYDROXY 2 NAPHTHOHYDRAZIDE; NONSTRUCTURAL PROTEIN 1; OSELTAMIVIR; UNCLASSIFIED DRUG; 3 HYDROXY N [1 (5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL)ETHYLIDENEAMINO]NAPHTHALENE 2 CARBOXAMIDE; AMIDE; ANTIVIRUS AGENT; IMINE; NAPHTHYL GROUP;

ANTIVIRAL ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG SYNTHESIS; FLUOROMETRY; INFLUENZA VIRUS A; MDCK CELL; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; VIRUS REPLICATION; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG SOLUBILITY; DRUG TARGETING; MDCK CELL LINE; MELTING POINT; NONHUMAN;

CARBOHYDRAZIDE; HEMAGGLUTININ; INFLUENZA; PLAQUE; REAL TIME PCR;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; HYDRAZINES; INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE INFECTIONS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84888172558     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.10.063     Document Type: Article

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