Skin permeation of d-limonene-based nanoemulsions as a transdermal carrier prepared by ultrasonic emulsification

Ultrasonics Sonochemistry

Volumn 21, Issue 2, 2014, Pages 826-832

  Lu, Wen Chien ^a   Chiang, Been Huang ^b   Huang, Da Wei ^c   Li, Po Hsien ^a  

^a DA YEH UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

d Limonene; Franz diffusion cell; Mixed surfactant; Nanoemulsions; Rat abdominal skin; Transdermal delivery

Indexed keywords

CONTROLLED DRUG DELIVERY; DERMATITIS; DROPS; EMULSIFICATION; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; MONOTERPENES; POLYETHYLENE OXIDES; RATS; SURFACE ACTIVE AGENTS; TARGETED DRUG DELIVERY; TRANSMISSION ELECTRON MICROSCOPY;

ABDOMINAL SKIN; D-LIMONENE; FRANZ DIFFUSION CELLS; MIXED SURFACTANT; NANO-EMULSIONS; TRANSDERMAL DELIVERY;

SKIN CARE PRODUCTS;

LIMONENE; POLYOXYETHYLENE; SORBITANE TRIOLEATE; SURFACTANT; UNCLASSIFIED DRUG;

ABDOMEN; ANIMAL TISSUE; ARTICLE; DIFFUSION; DRUG DELIVERY SYSTEM; EMULSION; ENCAPSULATION; GAS CHROMATOGRAPHY; HISTOPATHOLOGY; HYDROPHILICITY; IN VITRO STUDY; LIPOPHILICITY; MORPHOLOGY; NANOEMULSION; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; RAT; SKIN; SKIN CARE; SKIN PENETRATION; TRANSMISSION ELECTRON MICROSCOPY; ULTRASOUND;

D-LIMONENE; FRANZ DIFFUSION CELL; MIXED SURFACTANT; NANOEMULSIONS; RAT ABDOMINAL SKIN; TRANSDERMAL DELIVERY;

ADMINISTRATION, CUTANEOUS; ANIMALS; CYCLOHEXENES; DIFFUSION; DRUG CARRIERS; EMULSIONS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; NANOSTRUCTURES; PERMEABILITY; RATS; SKIN; TERPENES; ULTRASONICS;

EID: 84888137828     PISSN: 13504177     EISSN: 18732828     Source Type: Journal    
DOI: 10.1016/j.ultsonch.2013.10.013     Document Type: Article

References (44)

1. A. Kogan, and N. Garti Microemulsions as transdermal drug delivery vehicles Adv. Colloid Interface Sci. 123-126 16 2006 369 385
2. C.S. Asbill, A.F. El-Kattan, and B. Michniak Enhancement of transdermal drug delivery: chemical and physical approaches Crit. Rev. Ther. Drug Carrier Syst. 17 6 2000 621 658
3. B. Sapra, S. Jain, and A.K. Tiwary Percutaneous permeation enhancement by terpenes: mechanistic view AAPS PharmSciTech. 10 1 2008 120 132
4. A. Williams, and B.W. Barry Terpenes and the lipid-protein-partitioning theory of skin penetration enhancement Pharm. Res. 8 1 1991 17 24
5. M. Rizwan, M. Aqil, A. Ahad, Y. Sultana, and M.M. Ali Transdermal delivery of valsartan: I. Effect of various terpenes Drug Dev. Ind. Pharm. 34 6 2008 618 626
6. C. Solans, P. Izquierdo, J. Nolla, N. Azemar, and M.J. Garcia-Celma Nano-emulsions Curr. Opin. Colloid Interface Sci. 10 3-4 2005 102 110
7. Q. Huang, H. Yu, and Q. Ru Bioavailability and delivery of nutraceuticals using nanotechnology J. Food Sci. 75 1 2010 50 57
8. A. Soottitantawat, F. Bigeard, H. Yoshii, T. Furuta, M. Ohgawara, and P. Linko Influence of emulsion and power size on the stability of encapsulated d-limonene by spray drying Innov. Food Sci. Emerg. Technol. 6 2 2005 107 114
9. M.P. Youenang Piemi, D. Korner, S. Benita, and J.P. Marty Positively and negatively charged submicron emulsions for enhanced topical delivery of antifungal drugs J. Controlled Release 58 1999 177 187
10. Y. Yuan, S.M. Li, F.K. Mo, and D.F. Zhong Investigation of microemulsion system for transdermal delivery of meloxicam Int. J. Pharm. 321 1-2 2006 117 123
11. S. Hoeller, A. Sperger, and C. Valenta Lecithin based nanoemulsions: a comparative study of the influence of non-ionic surfactants and the cationic phytosphingosine on physicochemical behavior and skin permeation Int. J. Pharm. 370 1 2009 181 186
12. M.H.F. Sakeena, S.M. Elrashid, F.A. Muthanna, Z.A. Ghassan, M.M. Kanakal, L. Laila, A.S. Munavvar, and M.N. Azmin Effect of limonene on permeation enhancement of ketoprofen in palm oil esters nanoemulsions J. Oleo Sci. 59 7 2010 395 400
13. H. Zhou, Y. Yue, G. Liu, Y. Li, J. Zhang, Q. Gong, Z. Yan, and M. Duan Preparation and characterization of a lecithin nanoemulsion as a topical delivery system Nanoscale Res. Lett. 5 1 2010 224 230
14. W.W. Zheng, L. Zhao, Y.M. Wei, Y. Ye, and S.H. Xiao Preparation and in vitro evaluation of nanoemulsion system for the transdermal delivery of granisetron hydrochloride Chem. Pharm. Bull. 58 8 2010 1015 1019
15. G. Sonavane, K. Tomoda, A. Sano, H. Ohshima, H. Terada, and K. Makino In vitro permeation of gold nanoparticles through rat skin and rat intestine: effect of particle size Colloids Surf. B 65 1 2008 1 10
16. K. Zhao, and J. Singh Mechanisms of percutaneous absorption of tamoxifen by terpenes: eugenol, d-limonene and menthone J. Controlled Release 55 2-3 1998 253 260
17. P.F.C. Lim, X.Y. Liu, L. Kang, P.C.L. Ho, Y.W. Chan, and S.Y. Chan Limonene GP1/PG organogel as a vehicle in transdermal delivery of haloperidol Int. J. Pharm. 311 1-2 2006 157 164
18. Y. Koyama, H. Bando, F. Yamashita, Y. Takakura, H. Sezaki, and H. Hashida Comparative analysis of percutaneous absorption enhancement by d-limonene and oleic acid based on a skin diffusion model Pharm. Res. 11 3 1994 377 383
19. Y.S.R. Krishnaiah, V. Satyanarayana, and P. Bhaskar Influence of limonene on the bioavailability of nicardipine hydrochloride from membrane-moderated transdermal therapeutic systems in human volunteers Int. J. Pharm. 247 1-2 2002 91 102
20. A. Femenía-Fonta, C. Balaguer-Fernández, V. Merino, V. Rodilla, and A. Lópaz-Castellano Effect of chemical enhancers on the in vitro percutaneous absorption of sumatriptan succinate Eur. J. Pharm. Biopharm. 61 1-2 2005 50 55
21. P.H. Li, and B.H. Chiang Process optimization and stability of d-limonene-in-water nanoemulsions prepared by ultrasonic emulsification using response surface methodology Ultrason. Sonochem. 19 1 2012 192 197
22. V. Kaushik, and Y.H. Roos Limonene encapsulation in freeze-drying of gum arabic-sucrose-gelatin systems LWT - Food Sci. Technol. 40 8 2007 1381 1391
23. A. Soottitantawat, H. Yoshii, T. Furuta, M. Ohgawara, P. Forssell, R. Partanen, K. Poutanen, and P. Linko Effect of water activity on the release characteristics and oxidative stability of d-limonene encapsulated by spray drying J. Agric. Food Chem. 52 5 2004 1269 1276
24. S. Kentish, T.J. Wooster, M. Ashokkumar, S. Balachandran, R. Mawson, and L. Simons The use of ultrasonics for nanoemulsion preparation Innov. Food Sci. Emerg. 9 2 2008 170 175
25. T. Tadros, P. Izquierdo, J. Esquena, and C. Solans Formation and stability of nanoemulsions Adv. Colloid Interface 108-109 2004 303 318
26. S.M.H. Jafari, Y. He, and B. Bhandari Nano-emulsion production by sonication and microfluidization - a comparison Int. J. Food Prop. 9 3 2006 475 485
27. S. Jena, and H. Das Modeling of particle size distribution of sonicated coconut milk emulsion: effect of emulsifiers and sonication time Food Res. Int. 39 5 2006 606 611
28. C.Y. Lin, and L.W. Chen Emulsification characteristics of three- and two-phase emulsions prepared by the ultrasonic emulsification method Fuel Process. Technol. 87 4 2006 309 317
29. M. Bergström, and J.C. Eriksson A theoretical analysis of synergistic effects in mixed surfactant systems Langmuir 16 18 2000 7173 7181
30. P. Izquirerdo, J. Feng, J. Esquena, T.F. Tadros, J.C. Dederen, M.J. Garcia, N. Azemar, and C. Solans The influence of surfactant mixing ratio on nano-emulsion formation by the pit method J. Colloid Interface Sci. 285 1 2005 388 394
31. J.V.L. Henry, P.J. Fryer, W.J. Frith, and I.T. Norton Emulsification mechanism and storage instabilities of hydrocarbon-in-water sub-micron emulsions stabilized with Tweens (20 and 80), Brij 96v and sucrose monoesters J. Colloid Interface Sci. 338 1 2009 201 206
32. Z. Fu, M. Liu, J. Xu, Q. Wang, and Z. Fan Stabilization of water-in-octane nano-emulsion. Part I: stabilized by mixed surfactant systems Fuel 89 10 2010 2838 2843
33. A. Soottitantawat, H. Yoshii, T. Furuta, M. Ohkawara, and P. Linko Microencapsulation by spray drying: influence of emulsion size on the retention of volatile compounds J. Food Sci. 68 7 2003 2256 2262
34. A. Meynier, C. Lecoq, and C. Genot Emulsification enhances the retention of esters and aldehydes to a greater extent than changes in the droplet size distribution of the emulsion Food Chem. 93 1 2005 153 159
35. S.M. Jafari, Y. He, and B. Bhandari Nano-emulsion production by sonication and microfluidization - a comparison Int. J. Food Prop. 9 3 2006 475 485
36. I. Capek Degradation of kinetically-stable o/w emulsions Adv. Colloid Interface Sci. 107 2-3 2004 125 155
37. R.S. Juang, and K.H. Lin Ultrasound-assisted production of W/O emulsions in liquid surfactant membrane processes Colloids Surf. A 238 1-3 2004 43 49
38. J. Akimoto, K. Takayama, K. Isowa, and T. Nagai Evaluation of skin irritation of percutanceous absorption promoters by means of fractual dimension of rat skin structure Int. J. Pharm. 128 1-2 1996 251 260
39. N. Kanikkannan, and M. Singh Skin permeation enhancement effect and skin irritation of saturated fatty alcohols Int. J. Pharm. 248 1-2 2002 219 228
40. N. Nokhodchi, J. Shokri, A. Dashbolaghi, D. Hassan-Zadeh, T. Ghafourian, and M. Barzegar-Jalali The enhancement effect of surfactants on the penetration of lorazepam through rat skin Int. J. Pharm. 250 2 2003 359 369
41. J. Shim, H.S. Kang, W.S. Park, S.H. Han, J. Kim, and I.S. Chang Transdermal delivery of mixnoxidil with block copolymer nanoparticles J. Controlled Release 97 3 2004 477 484
42. K.A. Walters, M. Walker, and O. Olejnik Non-ionic surfactant effects on hairless mouse skin permeability characteristics J. Pharm. Pharmacol. 40 8 1988 525 529
43. D. Mou, H. Chen, D. Du, C. Mao, J. Wan, H. Xu, and X. Yang Hydrogel-thickened nanoemulsion system for topical delivery of lipophilic drugs Int. J. Pharm. 353 1-2 2008 270 276
44. M.J. Alvarez-Figueroa, and J. Blanco-Méndez Transdermal delivery of methotrexate: iontophoretic delivery from hydrogels and passive delivery from microemulsions Int. J. Pharm. 215 1-2 2001 57 65