Protective effects of Vaccinium arctostaphylos L., Berberis thunbergii var. atropurpurea chenault, Elaeagnus angustifolia L. and Launaea acanthodes (Boiss.) O. Kuntze against indomethacin-induced gastric ulcers in rats

Journal of Medicinal Plants

Volumn 12, Issue 47, 2013, Pages 62-69

  Fallah Huseini, H ^a   Kianbakht, S ^a   Hoormand, M ^a  

^a AVICENNA RESEARCH INSTITUTE   (Iran)

Author keywords

Anti ulcer; Herbal; Medicine; Rat; Traditional

Indexed keywords

ANTIULCER AGENT; BERBERIS THUNBERGII EXTRACT; ELAEAGNUS ANGUSTIFOLIA EXTRACT; INDOMETACIN; LAUNAEA ACANTHODES EXTRACT; OMEPRAZOLE; PLANT EXTRACT; UNCLASSIFIED DRUG; VACCINIUM ARCTOSTAPHYLOS EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIULCER ACTIVITY; ARTICLE; BERBERIS; BERBERIS THUNBERGII; COMPARATIVE STUDY; CONTROLLED STUDY; ELAEAGNUS ANGUSTIFOLIA; HERB; LAUNAEA ACANTHODES; MALE; NONHUMAN; RAT; STOMACH PROTECTION; STOMACH ULCER; VACCINIUM; VACCINIUM ARCTOSTAPHYLOS;

ACANTHODES; ANIMALIA; BERBERIS THUNBERGII; ELAEAGNUS ANGUSTIFOLIA; LAUNAEA; RATTUS; VACCINIUM ARCTOSTAPHYLOS;

EID: 84888071772     PISSN: 2717204X     EISSN: 27172058     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Roubille C, Martel-Pelletier J, Davy JM, Haraoui B and Pelletier JP. Cardiovascular adverse effects of anti-inflammatory drugs. Antiinflamm. Antiallergy Agents Med. Chem. 2013; 12: 55-67.
2. Gargallo CJ and Lanas A. Is NSAIDs-related gastrointestinal damage preventable? J. Dig. Dis. 2013; 14: 55-61.
3. Lee I and Cryer B. Epidemiology and role of nonsteroidal antiinflammatory drugs in causing gastrointestinal bleeding. Gastrointest. Endosc. Clin. N. Am. 2011; 21: 597-612.
4. Day RO and Graham GG. Non-steroidal anti-inflammatory drugs (NSAIDs). BMJ. 2013 Jun 11; 346: f3195. doi: 10.1136/bmj.f3195.
5. Abdulla A, Adams N, Bone M, Elliott AM, Gaffin J, Jones D, Knaggs R, Martin D, Sampson L and Schofield P. Guidance on the management of pain in older people. Age Ageing. 2013; 42 (Suppl. 1): i1-57.
6. Chan FK. NSAID-associated lower gastrointestinal bleeding: where do we stand? Clin. Gastroenterol. Hepatol. 2012; 10: 1060-1.
7. Ahmed A and Stanley AJ. Acute upper gastrointestinal bleeding in the elderly: aetiology, diagnosis and treatment. Drugs Aging. 2012; 29: 933-40.
8. Sinha M, Gautam L, Shukla PK, Kaur P, Sharma S and Singh TP. Current perspectives in NSAID-induced gastropathy. Mediators Inflamm. 2013; doi: 10.1155/2013/258209. Epub 2013 Mar 12.
9. Fogleman CD. Analgesics for osteoarthritis. Am. Fam. Physician. 2013; 87: 354-6.
10. Zhang S, Qing Q, Bai Y, Mao H, Zhu W, Chen Q, Zhang Y and Chen Y. Rebamipide helps defend against nonsteroidal anti-inflammatory drugs induced gastroenteropathy: a systematic review and meta-analysis. Dig. Dis. Sci. 2013; 58: 1991-2000.
11. Zhu LL, Xu LC, Chen Y, Zhou Q and Zeng S. Poor awareness of preventing aspirin-induced gastrointestinal injury with combined protective medications. World J. Gastroenterol. 2012; 18: 3167-72.
12. Scheiman JM. Prevention of damage induced by aspirin in the GI tract. Best Pract. Res. Clin. Gastroenetrol. 2012; 26: 153-62.
13. Wallace JL. Mechanisms, prevention and clinical implications of nonsteroidal anti-inflammatory drug-enteropathy. World J. Gastroenterol. 2013; 19: 1861-76.
14. Von Rahden BH, Scheurlen M, Filser J, Stein HJ and Germer CT. Newly recognized side-effects of proton pump inhibitors: arguments in favour of fundoplication for GERD? Chirurg. 2012; 83: 38-44.
15. Silverstein FE, Faich G, Goldstein JL, Simon LS, Pincus T, Whelton A, Makuch R, Eisen G, Agrawal NM, Stenson WF, Burr AM, Zhao WW, Kent JD, Lefkowith JB, Verburg KM and Geis GS. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: a randomized controlled trial. JAMA. 2000; 284: 1247-55.
16. Patricio JP, Barbosa JP, Ramos RM, Antunes NF and de Melo PC. Relative cardiovascular and gastrointestinal safety of non-selective non-steroidal anti-inflammatory drugs versus cyclo-oxygenase-2 inhibitors: implications for clinical practice. Clin. Drug Investig. 2013; 33: 167-83.
17. Nicoletti M. Nutraceuticals and botanicals: overview and perspectives. Int. J. Food Sci. Nutr. 2012; 63 (Suppl. 1): 2-6.
18. Latti AK, Kainulainen PS, Hayirlioglu-Ayaz S, Ayaz FA and Riihinen KR. Characterization of anthocyanins in Caucasian blueberries (Vaccinium arctostaphylos L.) native to Turkey. J. Agric. Food Chem. 2009. 57: 5244-9.
19. Kianbakht S and Hajiaghaee R. Antihyperglycemic effects of Vaccinium arctostaphylos L. fruit and leaf extracts in alloxan-induced diabetic rats. J. Med. Plants. 2013; 12: 53-60.
20. Wallace TC. Anthocyanins in cardiovascular disease. Adv. Nutr. 2011; 2: 1-7.
21. Zhang CR, Schutzki RE and Nair MG. Antioxidant and anti-inflammatory compounds in the popular landscape plant Berberis thunbergii var. atropurpurea. Nat. Prod. Commun. 2013; 8: 165-8.
22. Mozaffarian V. Identification of medicinal and aromatic plants of Iran. Farhang Moaser Publications. Iran. 2013, pp: 385-6.
23. Piazza L, Bertini S and Milany J. Extraction and structural characterization of the polysaccharide fraction of Launaea acanthodes gum. Carbohydrate Polymers. 2010; 79: 449-54.
24. Mozaffarian V. Identification of medicinal and aromatic plants of Iran. Farhang Moaser Publications. Iran. 2013, pp: 391-2.
25. Bhardwaj D and Kaushik N. Phytochemical and pharmacological studies in genus Berberis. Phytochem. Rev. 2012; 11: 523-42.
26. Chattopadhyay I, Bandyopadhyay U, Biswas K, Maity P and Banerjee RK. Indomethacin inactivates gastric peroxidase to induce reactive-oxygen-mediated gastric mucosal injury and curcumin protects it by preventing peroxidase inactivation and scavenging reactive oxygen. Free Radic. Biol. Med. 2006; 40: 1397-408.
27. D'Amelio, Sr. FS. Botanicals. CRC Press LLC. USA. 1999, pp: 39-41.
28. Rahman A, Iqbal Choudhary M and Thomson WJ. Bioassay techniques for drug development. Harwood Academic Publishers. The Netherlands. 2001, pp: 101-3.
29. Parmar NS and Prakash S. Screening methods in pharmacology. Alpha Science International Ltd. India. 2006, pp: 265-6.
30. Gurbuz I, Ustun O, Yesilada E, Sezik E and Kutsal O. Anti-ulcerogenic activity of some plants used as folk remedy in Turkey. J. Ethnopharmacol. 2003; 88: 93-7.
31. Magistretti MJ, Conti M and Cristoni A. Antiulcer activity of an anthocyanidin from Vaccinium myrtillus. Arzneimittelforschung. 1988; 38: 686-90.
32. Ogawa K, Oyagi A, Tanaka J, Kobayashi S and Hara H. The protective effect and action mechanism of vaccinium myrtillus L. on gastric ulcer in mice. Phytother. Res. 2011; 25: 1160-5.
33. Takeuchi K. Pathogenesis of NSAID-induced gastric damage: importance of cyclooxygenase inhibition and gastric hypermotility. World J. Gastroenterol. 2012; 18: 2147-60.
34. Lapenna D, de Gioia S, Ciofani G, Festi D and Cuccurullo F. Antioxidant properties of omeprazole. FEBS Lett. 1996; 382: 189-92.
35. Simon WA, Sturm E, Hartmann HJ and Weser U. Hydroxyl radical scavenging reactivity of proton pump inhibitors. Biochem. Pharmacol. 2006; 71: 1337-41.
36. Dembinska-Migas W and Gill S. Flavonoids in leaves of Elaeagnus angustifolia L. Pol. J. Pharmacol. Pharm. 1973; 25: 599-606.
37. Mahmudi Y and Yasa N. Structural investigation of Launaea acanthodes flavonoids. Ph.D. thesis, University of Tehran, Iran. 1995.