Therapeutics: Non-steroidal anti-inflammatory drugs (NSAIDs)

BMJ (Online)

Volumn 347, Issue 7917, 2013, Pages

  Day, Richard O ^a,b   Graham, Garry G ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b ST VINCENT S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANALGESIC AGENT; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTICOAGULANT AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CELECOXIB; COLCHICINE; CORTICOSTEROID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ETORICOXIB; IBUPROFEN; METFORMIN; METHOTREXATE; MISOPROSTOL; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE DERIVATIVE; PARACETAMOL; PLACEBO; PROSTAGLANDIN DERIVATIVE; PROTON PUMP INHIBITOR; SEROTONIN UPTAKE INHIBITOR; ANTIINFLAMMATORY AGENT;

ARTICLE; ASEPTIC MENINGITIS; ASPIRIN EXACERBATED RESPIRATORY DISEASE; BACKACHE; CARDIOVASCULAR DISEASE; CEREBROVASCULAR ACCIDENT; COGNITIVE DEFECT; CONSTIPATION; CROHN DISEASE; DIARRHEA; DIGESTIVE SYSTEM ULCER; DROWSINESS; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG MECHANISM; DRUG MILK LEVEL; DRUG MONITORING; DRUG RESPONSE; DRUG SAFETY; DYSMENORRHEA; DYSPEPSIA; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL TOXICITY; GOUT; HEART FAILURE; HEART INFARCTION; HUMAN; HYPERTENSION; INFLAMMATION; KIDNEY DISEASE; LACTATION; LIVER TOXICITY; LOW DRUG DOSE; NAUSEA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OSTEOARTHRITIS; PAIN; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SPONTANEOUS ABORTION; STEVENS JOHNSON SYNDROME; ULCER; ULCERATIVE COLITIS; AGED; CHEMICALLY INDUCED DISORDER; COMORBIDITY; DRUG COMBINATION; DRUG INTERACTION; FEMALE; GASTROINTESTINAL DISEASE; LOW BACK PAIN; MALE; MIDDLE AGED; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; AGED; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CARDIOVASCULAR DISEASES; COMORBIDITY; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; FEMALE; GASTROINTESTINAL DISEASES; HUMANS; INFLAMMATION; LOW BACK PAIN; MALE; MIDDLE AGED; OSTEOARTHRITIS;

EID: 84880579534     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Moore RA, Derry S, McQuay HJ, Wiffen PJ. Single dose oral analgesics for acute postoperative pain in adults. Cochrane Database Syst Rev 2011;(9):CD008659.
2. Massey T, Derry S, Moore RA, McQuay HJ. Topical NSAIDs for acute pain in adults. Cochrane Database Syst Rev 2010;(6):CD007402.
3. Marjoribanks J, Proctor M, Farquhar C, Derks RS. Nonsteroidal anti-inflammatory drugs for dysmenorrhoea. Cochrane Database Syst Rev 2010;(1):CD001751.
4. Zhang W, Nuki G, Moskowitz RW, Abramson S, Altman RD, Arden NK, et al. OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009. Osteoarthritis Cartilage 2010;18:476-99.
5. Derry S, Moore RA, Rabbie R. Topical NSAIDs for chronic musculoskeletal pain in adults. Cochrane Database Syst Rev 2012;(9):CD007400.
6. Roelofs PD, Deyo RA, Koes BW, Scholten RJ, van Tulder MW. Non-steroidal anti-inflammatory drugs for low back pain. Cochrane Database Syst Rev 2008;(1):CD000396.
7. Brooks P, Day R. Nonsteroidal antiinflammatory drugs-differences and similarities. N Engl J Med 1991;324:1716-25.
8. Zhang W, Doherty M, Bardin T, Pascual E, Barskova V, Conaghan P, et al. EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee For International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 2006;65:1312-24. (Pubitemid 44620440)
9. Terkeltaub RA, Furst DE, Bennett K, Kook KA, Crockett RS, Davis MW. High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study. Arthritis Rheum 2010;62:1060-8.
10. Strand V, Simon LS, Dougados M, Sands GH, Bhadra P, Breazna A, et al. Treatment with osteoarthritis with continuous versus intermittent celecoxib. J Rheumatol 2011;38:2625-34.
11. Roddy E, Zhang W, Doherty M. Aerobic walking or strengthening exercise for osteoarthritis of the knee? A systematic review. Ann Rheum Dis 2005;64:544-8. (Pubitemid 40469082)
12. National Institute for Health and Clinical Excellence. Osteoarthritis: the care and management of osteoarthritis in adults. (Clinical guideline 59.) 2008. www.nice.org.uk/CG059.
13. Laine L, White WB, Rostom A, Hochberg M. COX-2 selective inhibitors in the treatment of osteoarthritis. Semin Arthritis Rheum 2008;38:165-87.
14. Coxib and traditional NSAID Trialists' (CNT) Collaboration. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet 2013; doi:10.1016/S0140-6736(13)60900-9. [Epub ahead of print.]
15. Latimer N, Lord J, Grant RL, O'Mahony R, Dickson J, Conaghan PG, et al. Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis. BMJ 2009;339:b2538.
16. Adebajo A. Non-steroidal anti-inflammatory drugs for the treatment of pain and immobility-associated osteoarthritis: consensus guidance for primary care. BMC Fam Pract 2012;13:23.
17. Strand V. Are COX-2 inhibitors preferable to non-selective non-steroidal anti-inflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin? Lancet 2007;370:2138-51. (Pubitemid 350296305)
18. Hunt RH, Lanas A, Stichtenoth DO, Scarpignato C. Myths and facts in the use of anti-inflammatory drugs. Ann Med 2009;41:423-37.
19. Fortun P, Hawkey C. Nonsteroidal antiinflammatory drugs and the small intestine. Curr Opin Gastroenterol 2005;21:169-75. (Pubitemid 40316198)
20. Trelle S, Reichenbach S, Wandel S, Hildebrand P, Tschannen B, Villiger PM, et al. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ 2011;342:c7086.
21. McGettigan P, Henry D. Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies. PloS Med 2011;8:1-18.
22. Solomon DH, Goodson NJ. The cardiovascular system in rheumatic disease: the newest "extraarticular" manifestation? J Rheumatol 2005;32:1415-7. (Pubitemid 41113958)
23. Hao C, Breyer M. Physiological regulation of prostaglandins in the kidney. Annu Rev Physiol 2008;70:357-77. (Pubitemid 351738184)
24. Wilson S, Poulter N. The effect of non-steroidal anti-inflammatory drugs and other commonly used non-narcotic analgesics on blood pressure level in adults. J Hypertens 2006;24:1457-69. (Pubitemid 44162444)
25. Graham GG, Davies MJ, Day RO, Mohamudally A, Scott KF. The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings. Inflammopharmacology 2013; DOI 10.1007.
26. Stevenson D. Aspirin and NSAID sensitivity. Immunol Allergy Clin N Am 2004;24:495-505.
27. Nakhai-Pour HR, Broy P, Sheehy O, Bérard A. Use of nonaspirin nonsteroidal anti-inflammatory drugs during pregnancy and the risk of spontaneous abortion. CMAJ 2011;183:1713-20.
28. Risser A, Donovan D, Heintzman J, Page T. NSAID prescribing precautions. Am Fam Physician 2009;80:1371-8.
29. Hoppmann R, Peden J, Ober S. Central nervous system side effects of nonsteroidal anti-inflammatory drugs. Aseptic meningitis, psychosis, and cognitive dysfunction. Arch Intern Med 1991;151:1309-13.
30. Rostom A, Dube C, Wells G, Tugwell P, Welch V, Jolicoeur E, et al. Prevention of NSAID-induced gastroduodenal ulcers. Cochrane Database Syst Rev 2002;(4):CD002296.
31. Gardiner SJ, Doogue MP, Zhang M, Begg EJ. Quantification of infant exposure to celecoxib through breast milk. Br J Clin Pharmacol 2006;61:101-4. (Pubitemid 43381243)
32. Townsend RJ, Benedetti TJ, Erickson SH, Cengiz C, Gillespie WR, Gschwend J, et al. Excretion of ibuprofen into breast milk. Am J Obstet Gynecol 1984;149:184-6. (Pubitemid 14103914)
33. Solomon DH, Rassen JA, Glynn RJ, Garneau K, Levin R, Lee J, et al. The comparative safety of opioids for nonmalignant pain in older adults. Arch Intern Med 2010;170:1979-86.
34. Clin Risk. Welcome to the QRISK2-2013 risk calculator. http://qrisk.org.