-
1
-
-
20844463069
-
Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses
-
Abordo-Adesida, E., Follenzi, A., Barcia, C., Sciascia, S., Castro, M. G., Naldini, L., et al. (2005). Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses. Hum. Gene Ther. 16, 741-751.
-
(2005)
Hum. Gene Ther.
, vol.16
, pp. 741-751
-
-
Abordo-Adesida, E.1
Follenzi, A.2
Barcia, C.3
Sciascia, S.4
Castro, M.G.5
Naldini, L.6
-
2
-
-
80052406372
-
Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma
-
Ahmed, A. U., Thaci, B., Alexiades, N. G., Han, Y., Qian, S., Liu, F., et al. (2011a). Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma. Mol. Ther. 19, 1714-1726.
-
(2011)
Mol. Ther.
, vol.19
, pp. 1714-1726
-
-
Ahmed, A.U.1
Thaci, B.2
Alexiades, N.G.3
Han, Y.4
Qian, S.5
Liu, F.6
-
3
-
-
80053480063
-
A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma
-
Ahmed, A. U., Tyler, M. A., Thaci, B., Alexiades, N. G., Han, Y., Ulasov, I. V., et al. (2011b). A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma. Mol. Pharm. 8, 1559-1572.
-
(2011)
Mol. Pharm.
, vol.8
, pp. 1559-1572
-
-
Ahmed, A.U.1
Tyler, M.A.2
Thaci, B.3
Alexiades, N.G.4
Han, Y.5
Ulasov, I.V.6
-
4
-
-
80555127418
-
Targeting brain tumor stem cells with oncolytic adenoviruses
-
Alonso, M. M., Jiang, H., Gomez-Manzano, C., and Fueyo, J. (2012). Targeting brain tumor stem cells with oncolytic adenoviruses. Methods Mol. Biol. 797, 111-125.
-
(2012)
Methods Mol. Biol.
, vol.797
, pp. 111-125
-
-
Alonso, M.M.1
Jiang, H.2
Gomez-Manzano, C.3
Fueyo, J.4
-
5
-
-
0031963349
-
Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins
-
Andreansky, S., He, B., van Cott, J., McGhee, J., Markert, J. M., Gillespie, G. Y., et al. (1998). Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins. Gene Ther. 5, 121-130.
-
(1998)
Gene Ther.
, vol.5
, pp. 121-130
-
-
Andreansky, S.1
He, B.2
van Cott, J.3
McGhee, J.4
Markert, J.M.5
Gillespie, G.Y.6
-
6
-
-
1642553650
-
Defective translational control facilitates vesicular stomatitis virus oncolysis
-
Balachandran, S., and Barber, G. N. (2004). Defective translational control facilitates vesicular stomatitis virus oncolysis. Cancer Cell 5, 51-65.
-
(2004)
Cancer Cell
, vol.5
, pp. 51-65
-
-
Balachandran, S.1
Barber, G.N.2
-
8
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao, S., Wu, Q., McLendon, R. E., Hao, Y., Shi, Q., Hjelmeland, A. B., et al. (2006). Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444, 756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
-
9
-
-
0036118404
-
Replication-selective viruses for cancer therapy
-
Biederer, C., Ries, S., Brandts, C. H., and McCormick, F. (2002). Replication-selective viruses for cancer therapy. J. Mol. Med. (Berl.) 80, 163-175.
-
(2002)
J. Mol. Med. (Berl.)
, vol.80
, pp. 163-175
-
-
Biederer, C.1
Ries, S.2
Brandts, C.H.3
McCormick, F.4
-
10
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff, J. R., Kirn, D. H., Williams, A., Heise, C., Horn, S., Muna, M., et al. (1996). An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 274, 373-376.
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
Heise, C.4
Horn, S.5
Muna, M.6
-
11
-
-
23444437213
-
Convection-enhanced delivery of macromolecules in the brain
-
Bobo, R. H., Laske, D. W., Akbasak, A., Morrison, P. F., Dedrick, R. L., and Oldfield, E. H. (1994). Convection-enhanced delivery of macromolecules in the brain. Proc. Natl. Acad. Sci. U.S.A. 91, 2076-2080.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 2076-2080
-
-
Bobo, R.H.1
Laske, D.W.2
Akbasak, A.3
Morrison, P.F.4
Dedrick, R.L.5
Oldfield, E.H.6
-
12
-
-
0036516460
-
Matrix metalloproteinases: a tail of a frog that became a prince
-
Brinckerhoff, C. E., and Matrisian, L. M. (2002). Matrix metalloproteinases: a tail of a frog that became a prince. Nat. Rev. Mol. Cell Biol. 3, 207-214.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 207-214
-
-
Brinckerhoff, C.E.1
Matrisian, L.M.2
-
13
-
-
0347517726
-
Intravascular delivery of neural stem cell lines to target intracranial and extracranial tumors of neural and non-neural origin
-
Brown, A. B., Yang, W., Schmidt, N. O., Carroll, R., Leishear, K. K., Rainov, N. G., et al. (2003). Intravascular delivery of neural stem cell lines to target intracranial and extracranial tumors of neural and non-neural origin. Hum. Gene Ther. 14, 1777-1785.
-
(2003)
Hum. Gene Ther.
, vol.14
, pp. 1777-1785
-
-
Brown, A.B.1
Yang, W.2
Schmidt, N.O.3
Carroll, R.4
Leishear, K.K.5
Rainov, N.G.6
-
14
-
-
35449004503
-
Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression
-
Candolfi, M., Curtin, J. F., Nichols, W. S., Muhammad, A. G., King, G. D., Pluhar, G. E., et al. (2007). Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression. J. Neurooncol. 85, 133-148.
-
(2007)
J. Neurooncol.
, vol.85
, pp. 133-148
-
-
Candolfi, M.1
Curtin, J.F.2
Nichols, W.S.3
Muhammad, A.G.4
King, G.D.5
Pluhar, G.E.6
-
15
-
-
82555189374
-
Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts
-
Cheema, T. A., Kanai, R., Kim, G. W., Wakimoto, H., Passer, B., Rabkin, S. D., et al. (2011). Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts. Clin. Cancer Res. 17, 7383-7393.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 7383-7393
-
-
Cheema, T.A.1
Kanai, R.2
Kim, G.W.3
Wakimoto, H.4
Passer, B.5
Rabkin, S.D.6
-
16
-
-
0028856844
-
Effect of herpes simplex virus thymidine kinase expression levels on ganciclovir-mediated cytotoxicity and the bystander effect
-
Chen, C. Y., Chang, Y. N., Ryan, P., Linscott, M., McGarrity, G. J., and Chiang, Y. L. (1995). Effect of herpes simplex virus thymidine kinase expression levels on ganciclovir-mediated cytotoxicity and the bystander effect. Hum. Gene Ther. 6, 1467-1476.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1467-1476
-
-
Chen, C.Y.1
Chang, Y.N.2
Ryan, P.3
Linscott, M.4
McGarrity, G.J.5
Chiang, Y.L.6
-
17
-
-
7044228126
-
A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting
-
Chiocca, E. A., Abbed, K. M., Tatter, S., Louis, D. N., Hochberg, F. H., Barker, F., et al. (2004). A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Mol. Ther. 10, 958-966.
-
(2004)
Mol. Ther.
, vol.10
, pp. 958-966
-
-
Chiocca, E.A.1
Abbed, K.M.2
Tatter, S.3
Louis, D.N.4
Hochberg, F.H.5
Barker, F.6
-
18
-
-
80053061789
-
Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma
-
Chiocca, E. A., Aguilar, L. K., Bell, S. D., Kaur, B., Hardcastle, J., Cavaliere, R., et al. (2011). Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma. J. Clin. Oncol. 29, 3611-3619.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 3611-3619
-
-
Chiocca, E.A.1
Aguilar, L.K.2
Bell, S.D.3
Kaur, B.4
Hardcastle, J.5
Cavaliere, R.6
-
19
-
-
0025688373
-
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture
-
Chou, J., Kern, E. R., Whitley, R. J., and Roizman, B. (1990). Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science 250, 1262-1266.
-
(1990)
Science
, vol.250
, pp. 1262-1266
-
-
Chou, J.1
Kern, E.R.2
Whitley, R.J.3
Roizman, B.4
-
20
-
-
0032515141
-
Reovirus therapy of tumors with activated Ras pathway
-
Coffey, M. C., Strong, J. E., Forsyth, P. A., and Lee, P. W. (1998). Reovirus therapy of tumors with activated Ras pathway. Science 282, 1332-1334.
-
(1998)
Science
, vol.282
, pp. 1332-1334
-
-
Coffey, M.C.1
Strong, J.E.2
Forsyth, P.A.3
Lee, P.W.4
-
21
-
-
70349982431
-
HMGB1 mediates endogenous TLR2 activation and brain tumor regression
-
doi: 10.1371/journal.pmed.1000010
-
Curtin, J. F., Liu, N., Candolfi, M., Xiong, W., Assi, H., Yagiz, K., et al. (2009). HMGB1 mediates endogenous TLR2 activation and brain tumor regression. PLoS Med. 6:e10. doi: 10.1371/journal.pmed.1000010
-
(2009)
PLoS Med.
, vol.6
-
-
Curtin, J.F.1
Liu, N.2
Candolfi, M.3
Xiong, W.4
Assi, H.5
Yagiz, K.6
-
22
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean, M., Fojo, T., and Bates, S. (2005). Tumour stem cells and drug resistance. Nat. Rev. Cancer 5, 275-284.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
23
-
-
78751649494
-
Cancer stem cells: the final frontier for glioma virotherapy
-
Dey, M., Ulasov, I. V., Tyler, M. A., Sonabend, A. M., and Lesniak, M. S. (2011). Cancer stem cells: the final frontier for glioma virotherapy. Stem. Cell Rev. 7, 119-129.
-
(2011)
Stem. Cell Rev.
, vol.7
, pp. 119-129
-
-
Dey, M.1
Ulasov, I.V.2
Tyler, M.A.3
Sonabend, A.M.4
Lesniak, M.S.5
-
24
-
-
34547610960
-
AAV vector integration sites in mouse hepatocellular carcinoma
-
Donsante, A., Miller, D. G., Li, Y., Vogler, C., Brunt, E. M., Russell, D. W., et al. (2007). AAV vector integration sites in mouse hepatocellular carcinoma. Science 317, 477.
-
(2007)
Science
, vol.317
, pp. 477
-
-
Donsante, A.1
Miller, D.G.2
Li, Y.3
Vogler, C.4
Brunt, E.M.5
Russell, D.W.6
-
25
-
-
0028055043
-
Histological characteristics and expression of acidic and basic fibroblast growth factor genes in intracerebral xenogeneic transplants of human glioma cells
-
Finkelstein, S. D., Black, P., Nowak, T. P., Hand, C. M., Christensen, S., and Finch, P. W. (1994). Histological characteristics and expression of acidic and basic fibroblast growth factor genes in intracerebral xenogeneic transplants of human glioma cells. Neurosurgery 34, 136-143.
-
(1994)
Neurosurgery
, vol.34
, pp. 136-143
-
-
Finkelstein, S.D.1
Black, P.2
Nowak, T.P.3
Hand, C.M.4
Christensen, S.5
Finch, P.W.6
-
26
-
-
33749333727
-
Mouse models of brain tumors and their applications in preclinical trials
-
Fomchenko, E. I., and Holland, E. C. (2006). Mouse models of brain tumors and their applications in preclinical trials. Clin. Cancer Res. 12, 5288-5297.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5288-5297
-
-
Fomchenko, E.I.1
Holland, E.C.2
-
27
-
-
39849099798
-
A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas
-
Forsyth, P., Roldan, G., George, D., Wallace, C., Palmer, C. A., Morris, D., et al. (2008). A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas. Mol. Ther. 16, 627-632.
-
(2008)
Mol. Ther.
, vol.16
, pp. 627-632
-
-
Forsyth, P.1
Roldan, G.2
George, D.3
Wallace, C.4
Palmer, C.A.5
Morris, D.6
-
28
-
-
33644547005
-
Glioma virotherapy: effects of innate immune suppression and increased viral replication capacity
-
Friedman, A., Tian, J. P., Fulci, G., Chiocca, E. A., and Wang, J. (2006). Glioma virotherapy: effects of innate immune suppression and increased viral replication capacity. Cancer Res. 66, 2314-2319.
-
(2006)
Cancer Res.
, vol.66
, pp. 2314-2319
-
-
Friedman, A.1
Tian, J.P.2
Fulci, G.3
Chiocca, E.A.4
Wang, J.5
-
29
-
-
0038288854
-
Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway
-
Fueyo, J., Alemany, R., Gomez-Manzano, C., Fuller, G. N., Khan, A., Conrad, C. A., et al. (2003). Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway. J. Natl. Cancer Inst. 95, 652-660.
-
(2003)
J. Natl. Cancer Inst.
, vol.95
, pp. 652-660
-
-
Fueyo, J.1
Alemany, R.2
Gomez-Manzano, C.3
Fuller, G.N.4
Khan, A.5
Conrad, C.A.6
-
30
-
-
0034610723
-
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo
-
Fueyo, J., Gomez-Manzano, C., Alemany, R., Lee, P. S., McDonnell, T. J., Mitlianga, P., et al. (2000). A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene 19, 2-12.
-
(2000)
Oncogene
, vol.19
, pp. 2-12
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Alemany, R.3
Lee, P.S.4
McDonnell, T.J.5
Mitlianga, P.6
-
31
-
-
0032893489
-
Targeting in gene therapy for gliomas
-
Fueyo, J., Gomez-Manzano, C., Yung, W. K., and Kyritsis, A. P. (1999). Targeting in gene therapy for gliomas. Arch. Neurol. 56, 445-448.
-
(1999)
Arch. Neurol.
, vol.56
, pp. 445-448
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Yung, W.K.3
Kyritsis, A.P.4
-
32
-
-
33748088164
-
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses
-
Fulci, G., Breymann, L., Gianni, D., Kurozomi, K., Rhee, S. S., Yu, J., et al. (2006). Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses. Proc. Natl. Acad. Sci. U.S.A. 103, 12873-12878.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 12873-12878
-
-
Fulci, G.1
Breymann, L.2
Gianni, D.3
Kurozomi, K.4
Rhee, S.S.5
Yu, J.6
-
33
-
-
35148871720
-
Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses
-
Fulci, G., Dmitrieva, N., Gianni, D., Fontana, E. J., Pan, X., Lu, Y., et al. (2007). Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res. 67, 9398-9406.
-
(2007)
Cancer Res.
, vol.67
, pp. 9398-9406
-
-
Fulci, G.1
Dmitrieva, N.2
Gianni, D.3
Fontana, E.J.4
Pan, X.5
Lu, Y.6
-
34
-
-
0030138111
-
Novel costimulators in the immune gene therapy of cancer
-
Galea-Lauri, J., Farzaneh, F., and Gaken, J. (1996). Novel costimulators in the immune gene therapy of cancer. Cancer Gene Ther. 3, 202-214.
-
(1996)
Cancer Gene Ther.
, vol.3
, pp. 202-214
-
-
Galea-Lauri, J.1
Farzaneh, F.2
Gaken, J.3
-
35
-
-
52449091656
-
Intratumoral coadministration of hyaluronidase enzyme and oncolytic adenoviruses enhances virus potency in metastatic tumor models
-
Ganesh, S., Gonzalez-Edick, M., Gibbons, D., Van Roey, M., and Jooss, K. (2008). Intratumoral coadministration of hyaluronidase enzyme and oncolytic adenoviruses enhances virus potency in metastatic tumor models. Clin. Cancer Res. 14, 3933-3941.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3933-3941
-
-
Ganesh, S.1
Gonzalez-Edick, M.2
Gibbons, D.3
Van Roey, M.4
Jooss, K.5
-
36
-
-
34249316871
-
Relaxin-expressing, fiber chimeric oncolytic adenovirus prolongs survival of tumor-bearing mice
-
Ganesh, S., Gonzalez Edick, M., Idamakanti, N., Abramova, M., Vanroey, M., Robinson, M., et al. (2007). Relaxin-expressing, fiber chimeric oncolytic adenovirus prolongs survival of tumor-bearing mice. Cancer Res. 67, 4399-4407.
-
(2007)
Cancer Res.
, vol.67
, pp. 4399-4407
-
-
Ganesh, S.1
Gonzalez Edick, M.2
Idamakanti, N.3
Abramova, M.4
Vanroey, M.5
Robinson, M.6
-
37
-
-
0036468548
-
Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts
-
Geoerger, B., Grill, J., Opolon, P., Morizet, J., Aubert, G., Terrier-Lacombe, M. J., et al. (2002). Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts. Cancer Res. 62, 764-772.
-
(2002)
Cancer Res.
, vol.62
, pp. 764-772
-
-
Geoerger, B.1
Grill, J.2
Opolon, P.3
Morizet, J.4
Aubert, G.5
Terrier-Lacombe, M.J.6
-
38
-
-
11144356850
-
A novel E1A-E1B mutant adenovirus induces glioma regression in vivo
-
Gomez-Manzano, C., Balague, C., Alemany, R., Lemoine, M. G., Mitlianga, P., Jiang, H., et al. (2004). A novel E1A-E1B mutant adenovirus induces glioma regression in vivo. Oncogene 23, 1821-1828.
-
(2004)
Oncogene
, vol.23
, pp. 1821-1828
-
-
Gomez-Manzano, C.1
Balague, C.2
Alemany, R.3
Lemoine, M.G.4
Mitlianga, P.5
Jiang, H.6
-
39
-
-
84855559315
-
Gene therapy
-
Gomez-Manzano, C., Jiang, H., Alonso, M., Yung, W. K., and Fueyo, J. (2012). Gene therapy. Handb. Clin. Neurol. 104, 331-338.
-
(2012)
Handb. Clin. Neurol.
, vol.104
, pp. 331-338
-
-
Gomez-Manzano, C.1
Jiang, H.2
Alonso, M.3
Yung, W.K.4
Fueyo, J.5
-
40
-
-
77951003656
-
Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States
-
Grossman, S. A., Ye, X., Piantadosi, S., Desideri, S., Nabors, L. B., Rosenfeld, M., et al. (2010). Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States. Clin. Cancer Res. 16, 2443-2449.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 2443-2449
-
-
Grossman, S.A.1
Ye, X.2
Piantadosi, S.3
Desideri, S.4
Nabors, L.B.5
Rosenfeld, M.6
-
41
-
-
0017785769
-
Primary bioassay of human tumor stem cells
-
Hamburger, A. W., and Salmon, S. E. (1977). Primary bioassay of human tumor stem cells. Science 197, 461-463.
-
(1977)
Science
, vol.197
, pp. 461-463
-
-
Hamburger, A.W.1
Salmon, S.E.2
-
42
-
-
0033782862
-
An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy
-
Heise, C., Hermiston, T., Johnson, L., Brooks, G., Sampson-Johannes, A., Williams, A., et al. (2000). An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy. Nat. Med. 6, 1134-1139.
-
(2000)
Nat. Med.
, vol.6
, pp. 1134-1139
-
-
Heise, C.1
Hermiston, T.2
Johnson, L.3
Brooks, G.4
Sampson-Johannes, A.5
Williams, A.6
-
43
-
-
23144439443
-
Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model
-
Hellums, E. K., Markert, J. M., Parker, J. N., He, B., Perbal, B., Roizman, B., et al. (2005). Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro. Oncol. 7, 213-224.
-
(2005)
Neuro. Oncol.
, vol.7
, pp. 213-224
-
-
Hellums, E.K.1
Markert, J.M.2
Parker, J.N.3
He, B.4
Perbal, B.5
Roizman, B.6
-
44
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
Hermann, P. C., Huber, S. L., Herrler, T., Aicher, A., Ellwart, J. W., Guba, M., et al. (2007). Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1, 313-323.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
Guba, M.6
-
45
-
-
22144476218
-
Applications of mouse glioma models in preclinical trials
-
Hu, X., and Holland, E. C. (2005). Applications of mouse glioma models in preclinical trials. Mutat. Res. 576, 54-65.
-
(2005)
Mutat. Res.
, vol.576
, pp. 54-65
-
-
Hu, X.1
Holland, E.C.2
-
46
-
-
0037135078
-
Tech.Sight. Gene therapy. Hurdles and hopes for cancer treatment
-
Hunt, K. K., and Vorburger, S. A. (2002). Tech.Sight. Gene therapy. Hurdles and hopes for cancer treatment. Science 297, 415-416.
-
(2002)
Science
, vol.297
, pp. 415-416
-
-
Hunt, K.K.1
Vorburger, S.A.2
-
47
-
-
33846015067
-
Infected cell carriers: a new strategy for systemic delivery of oncolytic measles viruses in cancer virotherapy
-
Iankov, I. D., Blechacz, B., Liu, C., Schmeckpeper, J. D., Tarara, J. E., Federspiel, M. J., et al. (2007). Infected cell carriers: a new strategy for systemic delivery of oncolytic measles viruses in cancer virotherapy. Mol. Ther. 15, 114-122.
-
(2007)
Mol. Ther.
, vol.15
, pp. 114-122
-
-
Iankov, I.D.1
Blechacz, B.2
Liu, C.3
Schmeckpeper, J.D.4
Tarara, J.E.5
Federspiel, M.J.6
-
48
-
-
67349239329
-
Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity
-
Ilett, E. J., Prestwich, R. J., Kottke, T., Errington, F., Thompson, J. M., Harrington, K. J., et al. (2009). Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity. Gene Ther. 16, 689-699.
-
(2009)
Gene Ther.
, vol.16
, pp. 689-699
-
-
Ilett, E.J.1
Prestwich, R.J.2
Kottke, T.3
Errington, F.4
Thompson, J.M.5
Harrington, K.J.6
-
49
-
-
7044235842
-
AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study
-
Immonen, A., Vapalahti, M., Tyynela, K., Hurskainen, H., Sandmair, A., Vanninen, R., et al. (2004). AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study. Mol. Ther. 10, 967-972.
-
(2004)
Mol. Ther.
, vol.10
, pp. 967-972
-
-
Immonen, A.1
Vapalahti, M.2
Tyynela, K.3
Hurskainen, H.4
Sandmair, A.5
Vanninen, R.6
-
50
-
-
3242686373
-
Oncolytic adenoviruses for malignant glioma therapy
-
Jiang, H., Conrad, C., Fueyo, J., Gomez-Manzano, C., and Liu, T. J. (2003). Oncolytic adenoviruses for malignant glioma therapy. Front. Biosci. 8, d577-d588.
-
(2003)
Front. Biosci.
, vol.8
-
-
Jiang, H.1
Conrad, C.2
Fueyo, J.3
Gomez-Manzano, C.4
Liu, T.J.5
-
51
-
-
13444292787
-
Comparative effect of oncolytic adenoviruses with E1A-55 kDa or E1B-55 kDa deletions in malignant gliomas
-
Jiang, H., Gomez-Manzano, C., Alemany, R., Medrano, D., Alonso, M., Bekele, B. N., et al. (2005). Comparative effect of oncolytic adenoviruses with E1A-55 kDa or E1B-55 kDa deletions in malignant gliomas. Neoplasia 7, 48-56.
-
(2005)
Neoplasia
, vol.7
, pp. 48-56
-
-
Jiang, H.1
Gomez-Manzano, C.2
Alemany, R.3
Medrano, D.4
Alonso, M.5
Bekele, B.N.6
-
52
-
-
34748880650
-
Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death
-
Jiang, H., Gomez-Manzano, C., Aoki, H., Alonso, M. M., Kondo, S., McCormick, F., et al. (2007). Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death. J. Natl. Cancer Inst. 99, 1410-1414.
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 1410-1414
-
-
Jiang, H.1
Gomez-Manzano, C.2
Aoki, H.3
Alonso, M.M.4
Kondo, S.5
McCormick, F.6
-
53
-
-
0033831080
-
a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri, F. R., Nemunaitis, J., Ganly, I., Arseneau, J., Tannock, I. F., Romel, L., et al. (2000). a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat. Med. 6, 879-885.
-
(2000)
Nat. Med.
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
Arseneau, J.4
Tannock, I.F.5
Romel, L.6
-
54
-
-
33750207622
-
Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy
-
Kim, J. H., Lee, Y. S., Kim, H., Huang, J. H., Yoon, A. R., and Yun, C. O. (2006). Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy. J. Natl. Cancer Inst. 98, 1482-1493.
-
(2006)
J. Natl. Cancer Inst.
, vol.98
, pp. 1482-1493
-
-
Kim, J.H.1
Lee, Y.S.2
Kim, H.3
Huang, J.H.4
Yoon, A.R.5
Yun, C.O.6
-
55
-
-
34447132877
-
Reovirus and tumor oncolysis
-
Kim, M., Chung, Y. H., and Johnston, R. N. (2007). Reovirus and tumor oncolysis. J. Microbiol. 45, 187-192.
-
(2007)
J. Microbiol.
, vol.45
, pp. 187-192
-
-
Kim, M.1
Chung, Y.H.2
Johnston, R.N.3
-
56
-
-
21644457579
-
Midkine promoter-based conditionally replicative adenovirus for malignant glioma therapy
-
Kohno, S., Nakagawa, K., Hamada, K., Harada, H., Yamasaki, K., Hashimoto, K., et al. (2004). Midkine promoter-based conditionally replicative adenovirus for malignant glioma therapy. Oncol. Rep. 12, 73-78.
-
(2004)
Oncol. Rep.
, vol.12
, pp. 73-78
-
-
Kohno, S.1
Nakagawa, K.2
Hamada, K.3
Harada, H.4
Yamasaki, K.5
Hashimoto, K.6
-
57
-
-
0035422652
-
Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter
-
Komata, T., Kondo, Y., Kanzawa, T., Hirohata, S., Koga, S., Sumiyoshi, H., et al. (2001). Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter. Cancer Res. 61, 5796-5802.
-
(2001)
Cancer Res.
, vol.61
, pp. 5796-5802
-
-
Komata, T.1
Kondo, Y.2
Kanzawa, T.3
Hirohata, S.4
Koga, S.5
Sumiyoshi, H.6
-
58
-
-
77951838524
-
Antiangiogenic cancer therapy combined with oncolytic virotherapy leads to regression of established tumors in mice
-
Kottke, T., Hall, G., Pulido, J., Diaz, R. M., Thompson, J., Chong, H., et al. (2010). Antiangiogenic cancer therapy combined with oncolytic virotherapy leads to regression of established tumors in mice. J. Clin. Invest. 120, 1551-1560.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1551-1560
-
-
Kottke, T.1
Hall, G.2
Pulido, J.3
Diaz, R.M.4
Thompson, J.5
Chong, H.6
-
59
-
-
0034331161
-
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy
-
Kuriyama, N., Kuriyama, H., Julin, C. M., Lamborn, K., and Israel, M. A. (2000). Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy. Hum. Gene Ther. 11, 2219-2230.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 2219-2230
-
-
Kuriyama, N.1
Kuriyama, H.2
Julin, C.M.3
Lamborn, K.4
Israel, M.A.5
-
60
-
-
38449114010
-
Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy
-
Kurozumi, K., Hardcastle, J., Thakur, R., Yang, M., Christoforidis, G., Fulci, G., et al. (2007). Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy. J. Natl. Cancer Inst. 99, 1768-1781.
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 1768-1781
-
-
Kurozumi, K.1
Hardcastle, J.2
Thakur, R.3
Yang, M.4
Christoforidis, G.5
Fulci, G.6
-
61
-
-
0037109013
-
Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy
-
Lamfers, M. L., Grill, J., Dirven, C. M., Van Beusechem, V. W., Geoerger, B., Van Den Berg, J., et al. (2002). Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy. Cancer Res. 62, 5736-5742.
-
(2002)
Cancer Res.
, vol.62
, pp. 5736-5742
-
-
Lamfers, M.L.1
Grill, J.2
Dirven, C.M.3
Van Beusechem, V.W.4
Geoerger, B.5
Van Den Berg, J.6
-
62
-
-
85047697641
-
Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results
-
Lang, F. F., Bruner, J. M., Fuller, G. N., Aldape, K., Prados, M. D., Chang, S., et al. (2003). Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results. J. Clin. Oncol. 21, 2508-2518.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2508-2518
-
-
Lang, F.F.1
Bruner, J.M.2
Fuller, G.N.3
Aldape, K.4
Prados, M.D.5
Chang, S.6
-
63
-
-
4644289015
-
Oncolytic viral therapies
-
Lin, E., and Nemunaitis, J. (2004). Oncolytic viral therapies. Cancer Gene Ther. 11, 643-664.
-
(2004)
Cancer Gene Ther.
, vol.11
, pp. 643-664
-
-
Lin, E.1
Nemunaitis, J.2
-
64
-
-
0031666608
-
Pre-treatment with elastase improves the efficiency of percutaneous adenovirus-mediated gene transfer to the arterial media
-
Maillard, L., Ziol, M., Tahlil, O., Le Feuvre, C., Feldman, L. J., Branellec, D., et al. (1998). Pre-treatment with elastase improves the efficiency of percutaneous adenovirus-mediated gene transfer to the arterial media. Gene Ther. 5, 1023-1030.
-
(1998)
Gene Ther.
, vol.5
, pp. 1023-1030
-
-
Maillard, L.1
Ziol, M.2
Tahlil, O.3
Le Feuvre, C.4
Feldman, L.J.5
Branellec, D.6
-
65
-
-
23044462079
-
Convection-enhanced drug delivery: increased efficacy and magnetic resonance image monitoring
-
Mardor, Y., Rahav, O., Zauberman, Y., Lidar, Z., Ocherashvilli, A., Daniels, D., et al. (2005). Convection-enhanced drug delivery: increased efficacy and magnetic resonance image monitoring. Cancer Res. 65, 6858-6863.
-
(2005)
Cancer Res.
, vol.65
, pp. 6858-6863
-
-
Mardor, Y.1
Rahav, O.2
Zauberman, Y.3
Lidar, Z.4
Ocherashvilli, A.5
Daniels, D.6
-
66
-
-
58149237728
-
Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM
-
Markert, J. M., Liechty, P. G., Wang, W., Gaston, S., Braz, E., Karrasch, M., et al. (2009). Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM. Mol. Ther. 17, 199-207.
-
(2009)
Mol. Ther.
, vol.17
, pp. 199-207
-
-
Markert, J.M.1
Liechty, P.G.2
Wang, W.3
Gaston, S.4
Braz, E.5
Karrasch, M.6
-
67
-
-
12944315014
-
Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial
-
Markert, J. M., Medlock, M. D., Rabkin, S. D., Gillespie, G. Y., Todo, T., Hunter, W. D., et al. (2000). Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Ther. 7, 867-874.
-
(2000)
Gene Ther.
, vol.7
, pp. 867-874
-
-
Markert, J.M.1
Medlock, M.D.2
Rabkin, S.D.3
Gillespie, G.Y.4
Todo, T.5
Hunter, W.D.6
-
68
-
-
33645066093
-
Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector
-
McKee, T. D., Grandi, P., Mok, W., Alexandrakis, G., Insin, N., Zimmer, J. P., et al. (2006). Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector. Cancer Res. 66, 2509-2513.
-
(2006)
Cancer Res.
, vol.66
, pp. 2509-2513
-
-
McKee, T.D.1
Grandi, P.2
Mok, W.3
Alexandrakis, G.4
Insin, N.5
Zimmer, J.P.6
-
69
-
-
0029023868
-
Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
-
Mineta, T., Rabkin, S. D., Yazaki, T., Hunter, W. D., and Martuza, R. L. (1995). Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat. Med. 1, 938-943.
-
(1995)
Nat. Med.
, vol.1
, pp. 938-943
-
-
Mineta, T.1
Rabkin, S.D.2
Yazaki, T.3
Hunter, W.D.4
Martuza, R.L.5
-
70
-
-
0034194841
-
Therapeutic efficiency of IL-2 gene transduced tumor vaccine for head and neck carcinoma
-
Mizuno, H., Yanoma, S., Nishimura, G., Hattori, S., Ito, T., Okudera, K., et al. (2000). Therapeutic efficiency of IL-2 gene transduced tumor vaccine for head and neck carcinoma. Cancer Lett. 152, 175-185.
-
(2000)
Cancer Lett.
, vol.152
, pp. 175-185
-
-
Mizuno, H.1
Yanoma, S.2
Nishimura, G.3
Hattori, S.4
Ito, T.5
Okudera, K.6
-
71
-
-
36348930079
-
Matrix metalloproteinases-1 and-8 improve the distribution and efficacy of an oncolytic virus
-
Mok, W., Boucher, Y., and Jain, R. K. (2007). Matrix metalloproteinases-1 and-8 improve the distribution and efficacy of an oncolytic virus. Cancer Res. 67, 10664-10668.
-
(2007)
Cancer Res.
, vol.67
, pp. 10664-10668
-
-
Mok, W.1
Boucher, Y.2
Jain, R.K.3
-
72
-
-
48649100068
-
Low-dose radiation enhances survivin-mediated virotherapy against malignant glioma stem cells
-
Nandi, S., Ulasov, I. V., Tyler, M. A., Sugihara, A. Q., Molinero, L., Han, Y., et al. (2008). Low-dose radiation enhances survivin-mediated virotherapy against malignant glioma stem cells. Cancer Res. 68, 5778-5784.
-
(2008)
Cancer Res.
, vol.68
, pp. 5778-5784
-
-
Nandi, S.1
Ulasov, I.V.2
Tyler, M.A.3
Sugihara, A.Q.4
Molinero, L.5
Han, Y.6
-
73
-
-
0019048265
-
Reversible osmotic blood-brain barrier disruption in humans: implications for the chemotherapy of malignant brain tumors
-
Neuwelt, E. A. (1980). Reversible osmotic blood-brain barrier disruption in humans: implications for the chemotherapy of malignant brain tumors. Neurosurgery 7, 204.
-
(1980)
Neurosurgery
, vol.7
, pp. 204
-
-
Neuwelt, E.A.1
-
74
-
-
50549097330
-
Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses
-
Otsuki, A., Patel, A., Kasai, K., Suzuki, M., Kurozumi, K., Chiocca, E. A., et al. (2008). Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses. Mol. Ther. 16, 1546-1555.
-
(2008)
Mol. Ther.
, vol.16
, pp. 1546-1555
-
-
Otsuki, A.1
Patel, A.2
Kasai, K.3
Suzuki, M.4
Kurozumi, K.5
Chiocca, E.A.6
-
75
-
-
67649097421
-
Oncolytic viral therapy of malignant glioma
-
Parker, J. N., Bauer, D. F., Cody, J. J., and Markert, J. M. (2009). Oncolytic viral therapy of malignant glioma. Neurotherapeutics 6, 558-569.
-
(2009)
Neurotherapeutics
, vol.6
, pp. 558-569
-
-
Parker, J.N.1
Bauer, D.F.2
Cody, J.J.3
Markert, J.M.4
-
76
-
-
0034050884
-
Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors
-
Parker, J. N., Gillespie, G. Y., Love, C. E., Randall, S., Whitley, R. J., and Markert, J. M. (2000). Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. Proc. Natl. Acad. Sci. U.S.A. 97, 2208-2213.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 2208-2213
-
-
Parker, J.N.1
Gillespie, G.Y.2
Love, C.E.3
Randall, S.4
Whitley, R.J.5
Markert, J.M.6
-
77
-
-
0033001621
-
Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion
-
Pelengaris, S., Littlewood, T., Khan, M., Elia, G., and Evan, G. (1999). Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Mol. Cell 3, 565-577.
-
(1999)
Mol. Cell
, vol.3
, pp. 565-577
-
-
Pelengaris, S.1
Littlewood, T.2
Khan, M.3
Elia, G.4
Evan, G.5
-
78
-
-
34547092699
-
Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4
-
Post, D. E., Sandberg, E. M., Kyle, M. M., Devi, N. S., Brat, D. J., Xu, Z., et al. (2007). Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4. Cancer Res. 67, 6872-6881.
-
(2007)
Cancer Res.
, vol.67
, pp. 6872-6881
-
-
Post, D.E.1
Sandberg, E.M.2
Kyle, M.M.3
Devi, N.S.4
Brat, D.J.5
Xu, Z.6
-
79
-
-
0037509944
-
A novel hypoxia-inducible factor (HIF) activated oncolytic adenovirus for cancer therapy
-
Post, D. E., and Van Meir, E. G. (2003). A novel hypoxia-inducible factor (HIF) activated oncolytic adenovirus for cancer therapy. Oncogene 22, 2065-2072.
-
(2003)
Oncogene
, vol.22
, pp. 2065-2072
-
-
Post, D.E.1
Van Meir, E.G.2
-
80
-
-
33845994768
-
Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity
-
Power, A. T., Wang, J., Falls, T. J., Paterson, J. M., Parato, K. A., Lichty, B. D., et al. (2007). Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity. Mol. Ther. 15, 123-130.
-
(2007)
Mol. Ther.
, vol.15
, pp. 123-130
-
-
Power, A.T.1
Wang, J.2
Falls, T.J.3
Paterson, J.M.4
Parato, K.A.5
Lichty, B.D.6
-
81
-
-
38049051428
-
Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy
-
Qiao, J., Kottke, T., Willmon, C., Galivo, F., Wongthida, P., Diaz, R. M., et al. (2008). Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy. Nat. Med. 14, 37-44.
-
(2008)
Nat. Med.
, vol.14
, pp. 37-44
-
-
Qiao, J.1
Kottke, T.2
Willmon, C.3
Galivo, F.4
Wongthida, P.5
Diaz, R.M.6
-
82
-
-
42149192000
-
Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansion
-
Quinlan, M. P., Quatela, S. E., Philips, M. R., and Settleman, J. (2008). Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansion. Mol. Cell. Biol. 28, 2659-2674.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 2659-2674
-
-
Quinlan, M.P.1
Quatela, S.E.2
Philips, M.R.3
Settleman, J.4
-
83
-
-
1242324630
-
Carrier cell-mediated delivery of oncolytic parvoviruses for targeting metastases
-
Raykov, Z., Balboni, G., Aprahamian, M., and Rommelaere, J. (2004). Carrier cell-mediated delivery of oncolytic parvoviruses for targeting metastases. Int. J. Cancer 109, 742-749.
-
(2004)
Int. J. Cancer
, vol.109
, pp. 742-749
-
-
Raykov, Z.1
Balboni, G.2
Aprahamian, M.3
Rommelaere, J.4
-
84
-
-
0042063604
-
Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene-a phase I/II clinical protocol
-
Ren, H., Boulikas, T., Lundstrom, K., Soling, A., Warnke, P. C., and Rainov, N. G. (2003). Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene-a phase I/II clinical protocol. J. Neurooncol. 64, 147-154.
-
(2003)
J. Neurooncol.
, vol.64
, pp. 147-154
-
-
Ren, H.1
Boulikas, T.2
Lundstrom, K.3
Soling, A.4
Warnke, P.C.5
Rainov, N.G.6
-
85
-
-
4644324025
-
Cancer immunotherapy: moving beyond current vaccines
-
Rosenberg, S. A., Yang, J. C., and Restifo, N. P. (2004). Cancer immunotherapy: moving beyond current vaccines. Nat. Med. 10, 909-915.
-
(2004)
Nat. Med.
, vol.10
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
86
-
-
0034329438
-
Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses
-
Sandmair, A. M., Loimas, S., Puranen, P., Immonen, A., Kossila, M., Puranen, M., et al. (2000). Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses. Hum. Gene Ther. 11, 2197-2205.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 2197-2205
-
-
Sandmair, A.M.1
Loimas, S.2
Puranen, P.3
Immonen, A.4
Kossila, M.5
Puranen, M.6
-
87
-
-
0018742048
-
Human brain tumor transplantation into nude mice
-
Shapiro, W. R., Basler, G. A., Chernik, N. L., and Posner, J. B. (1979). Human brain tumor transplantation into nude mice. J. Natl. Cancer Inst. 62, 447-453.
-
(1979)
J. Natl. Cancer Inst.
, vol.62
, pp. 447-453
-
-
Shapiro, W.R.1
Basler, G.A.2
Chernik, N.L.3
Posner, J.B.4
-
88
-
-
62549149856
-
Biodistribution of an oncolytic adenovirus after intracranial injection in permissive animals: a comparative study of Syrian hamsters and cotton rats
-
Sonabend, A. M., Ulasov, I. V., Han, Y., Rolle, C. E., Nandi, S., Cao, D., et al. (2009). Biodistribution of an oncolytic adenovirus after intracranial injection in permissive animals: a comparative study of Syrian hamsters and cotton rats. Cancer Gene Ther. 16, 362-372.
-
(2009)
Cancer Gene Ther.
, vol.16
, pp. 362-372
-
-
Sonabend, A.M.1
Ulasov, I.V.2
Han, Y.3
Rolle, C.E.4
Nandi, S.5
Cao, D.6
-
89
-
-
43049095411
-
Mesenchymal stem cells effectively deliver an oncolytic adenovirus to intracranial glioma
-
Sonabend, A. M., Ulasov, I. V., Tyler, M. A., Rivera, A. A., Mathis, J. M., and Lesniak, M. S. (2008). Mesenchymal stem cells effectively deliver an oncolytic adenovirus to intracranial glioma. Stem Cells 26, 831-841.
-
(2008)
Stem Cells
, vol.26
, pp. 831-841
-
-
Sonabend, A.M.1
Ulasov, I.V.2
Tyler, M.A.3
Rivera, A.A.4
Mathis, J.M.5
Lesniak, M.S.6
-
90
-
-
36048971746
-
Myxoma virus expressing human interleukin-12 does not induce myxomatosis in European rabbits
-
Stanford, M. M., Barrett, J. W., Gilbert, P. A., Bankert, R., and McFadden, G. (2007). Myxoma virus expressing human interleukin-12 does not induce myxomatosis in European rabbits. J. Virol. 81, 12704-12708.
-
(2007)
J. Virol.
, vol.81
, pp. 12704-12708
-
-
Stanford, M.M.1
Barrett, J.W.2
Gilbert, P.A.3
Bankert, R.4
McFadden, G.5
-
91
-
-
33947603295
-
Design of randomized controlled trials
-
Stanley, K. (2007). Design of randomized controlled trials. Circulation 115, 1164-1169.
-
(2007)
Circulation
, vol.115
, pp. 1164-1169
-
-
Stanley, K.1
-
92
-
-
29144520504
-
Antitumor efficacy of AAV-mediated systemic delivery of interferon-beta
-
Streck, C. J., Dickson, P. V., Ng, C. Y., Zhou, J., Hall, M. M., Gray, J. T., et al. (2006). Antitumor efficacy of AAV-mediated systemic delivery of interferon-beta. Cancer Gene Ther. 13, 99-106.
-
(2006)
Cancer Gene Ther.
, vol.13
, pp. 99-106
-
-
Streck, C.J.1
Dickson, P.V.2
Ng, C.Y.3
Zhou, J.4
Hall, M.M.5
Gray, J.T.6
-
93
-
-
0032526693
-
The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus
-
Strong, J. E., Coffey, M. C., Tang, D., Sabinin, P., and Lee, P. W. (1998). The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus. EMBO J. 17, 3351-3362.
-
(1998)
EMBO J.
, vol.17
, pp. 3351-3362
-
-
Strong, J.E.1
Coffey, M.C.2
Tang, D.3
Sabinin, P.4
Lee, P.W.5
-
94
-
-
33846876273
-
Targeting brain-tumor stem cells
-
Stupp, R., and Hegi, M. E. (2007). Targeting brain-tumor stem cells. Nat. Biotechnol. 25, 193-194.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 193-194
-
-
Stupp, R.1
Hegi, M.E.2
-
95
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp, R., Mason, W. P., van den Bent, M. J., Weller, M., Fisher, B., Taphoorn, M. J., et al. (2005). Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352, 987-996.
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
-
96
-
-
66549083540
-
Malignant glioma: ESMO clinical recommendations for diagnosis, treatment and follow-up
-
Stupp, R., and Roila, F. (2009). Malignant glioma: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann. Oncol. 20(Suppl. 4), 126-128.
-
(2009)
Ann. Oncol.
, vol.20
, Issue.SUPPL. 4
, pp. 126-128
-
-
Stupp, R.1
Roila, F.2
-
97
-
-
0035138689
-
A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency
-
Suzuki, K., Fueyo, J., Krasnykh, V., Reynolds, P. N., Curiel, D. T., and Alemany, R. (2001). A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency. Clin. Cancer Res. 7, 120-126.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 120-126
-
-
Suzuki, K.1
Fueyo, J.2
Krasnykh, V.3
Reynolds, P.N.4
Curiel, D.T.5
Alemany, R.6
-
98
-
-
0142213122
-
HSV-1 therapy of primary tumors reduces the number of metastases in an immune-competent model of metastatic breast cancer
-
Thomas, D. L., and Fraser, N. W. (2003). HSV-1 therapy of primary tumors reduces the number of metastases in an immune-competent model of metastatic breast cancer. Mol. Ther. 8, 543-551.
-
(2003)
Mol. Ther.
, vol.8
, pp. 543-551
-
-
Thomas, D.L.1
Fraser, N.W.2
-
99
-
-
33645239282
-
Synergistic antitumor effects of immune cell-viral biotherapy
-
Thorne, S. H., Negrin, R. S., and Contag, C. H. (2006). Synergistic antitumor effects of immune cell-viral biotherapy. Science 311, 1780-1784.
-
(2006)
Science
, vol.311
, pp. 1780-1784
-
-
Thorne, S.H.1
Negrin, R.S.2
Contag, C.H.3
-
100
-
-
84862976494
-
Active immunotherapy: oncolytic virus therapy using HSV-1
-
Todo, T. (2012). Active immunotherapy: oncolytic virus therapy using HSV-1. Adv. Exp. Med. Biol. 746, 178-186.
-
(2012)
Adv. Exp. Med. Biol.
, vol.746
, pp. 178-186
-
-
Todo, T.1
-
101
-
-
0035138174
-
In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity
-
Todo, T., Martuza, R. L., Dallman, M. J., and Rabkin, S. D. (2001a). In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity. Cancer Res. 61, 153-161.
-
(2001)
Cancer Res.
, vol.61
, pp. 153-161
-
-
Todo, T.1
Martuza, R.L.2
Dallman, M.J.3
Rabkin, S.D.4
-
102
-
-
0035933088
-
Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing
-
Todo, T., Martuza, R. L., Rabkin, S. D., and Johnson, P. A. (2001b). Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing. Proc. Natl. Acad. Sci. U.S.A. 98, 6396-6401.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 6396-6401
-
-
Todo, T.1
Martuza, R.L.2
Rabkin, S.D.3
Johnson, P.A.4
-
103
-
-
0033589694
-
Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus
-
Todo, T., Rabkin, S. D., Sundaresan, P., Wu, A., Meehan, K. R., Herscowitz, H. B., et al. (1999). Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. Hum. Gene Ther. 10, 2741-2755.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 2741-2755
-
-
Todo, T.1
Rabkin, S.D.2
Sundaresan, P.3
Wu, A.4
Meehan, K.R.5
Herscowitz, H.B.6
-
104
-
-
60449099546
-
Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo
-
Tyler, M. A., Ulasov, I. V., Sonabend, A. M., Nandi, S., Han, Y., Marler, S., et al. (2009). Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo. Gene Ther. 16, 262-278.
-
(2009)
Gene Ther.
, vol.16
, pp. 262-278
-
-
Tyler, M.A.1
Ulasov, I.V.2
Sonabend, A.M.3
Nandi, S.4
Han, Y.5
Marler, S.6
-
105
-
-
34848897229
-
An oncolytic adenoviral vector carrying the tyrosinase promoter for glioma gene therapy
-
Ulasov, I. V., Rivera, A. A., Nettelbeck, D. M., Rivera, L. B., Mathis, J. M., Sonabend, A. M., et al. (2007a). An oncolytic adenoviral vector carrying the tyrosinase promoter for glioma gene therapy. Int. J. Oncol. 31, 1177-1185.
-
(2007)
Int. J. Oncol.
, vol.31
, pp. 1177-1185
-
-
Ulasov, I.V.1
Rivera, A.A.2
Nettelbeck, D.M.3
Rivera, L.B.4
Mathis, J.M.5
Sonabend, A.M.6
-
106
-
-
34547515098
-
Comparative evaluation of survivin, midkine and CXCR4 promoters for transcriptional targeting of glioma gene therapy
-
Ulasov, I. V., Rivera, A. A., Sonabend, A. M., Rivera, L. B., Wang, M., Zhu, Z. B., et al. (2007b). Comparative evaluation of survivin, midkine and CXCR4 promoters for transcriptional targeting of glioma gene therapy. Cancer Biol. Ther. 6, 679-685.
-
(2007)
Cancer Biol. Ther.
, vol.6
, pp. 679-685
-
-
Ulasov, I.V.1
Rivera, A.A.2
Sonabend, A.M.3
Rivera, L.B.4
Wang, M.5
Zhu, Z.B.6
-
107
-
-
34547523121
-
Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma
-
Ulasov, I. V., Zhu, Z. B., Tyler, M. A., Han, Y., Rivera, A. A., Khramtsov, A., et al. (2007c). Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma. Hum. Gene Ther. 18, 589-602.
-
(2007)
Hum. Gene Ther.
, vol.18
, pp. 589-602
-
-
Ulasov, I.V.1
Zhu, Z.B.2
Tyler, M.A.3
Han, Y.4
Rivera, A.A.5
Khramtsov, A.6
-
108
-
-
48249085659
-
Evaluation of E1A double mutant oncolytic adenovectors in anti-glioma gene therapy
-
Ulasov, I. V., Tyler, M. A., Rivera, A. A., Nettlebeck, D. M., Douglas, J. T., and Lesniak, M. S. (2008). Evaluation of E1A double mutant oncolytic adenovectors in anti-glioma gene therapy. J. Med. Virol. 80, 1595-1603.
-
(2008)
J. Med. Virol.
, vol.80
, pp. 1595-1603
-
-
Ulasov, I.V.1
Tyler, M.A.2
Rivera, A.A.3
Nettlebeck, D.M.4
Douglas, J.T.5
Lesniak, M.S.6
-
109
-
-
0036187968
-
Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolished
-
van Beusechem, V. W., Grill, J., Mastenbroek, D. C., Wickham, T. J., Roelvink, P. W., Haisma, H. J., et al. (2002). Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolished. J. Virol. 76, 2753-2762.
-
(2002)
J. Virol.
, vol.76
, pp. 2753-2762
-
-
van Beusechem, V.W.1
Grill, J.2
Mastenbroek, D.C.3
Wickham, T.J.4
Roelvink, P.W.5
Haisma, H.J.6
-
110
-
-
33645552398
-
The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma
-
Van Houdt, W. J., Haviv, Y. S., Lu, B., Wang, M., Rivera, A. A., Ulasov, I. V., et al. (2006). The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma. J. Neurosurg. 104, 583-592.
-
(2006)
J. Neurosurg.
, vol.104
, pp. 583-592
-
-
Van Houdt, W.J.1
Haviv, Y.S.2
Lu, B.3
Wang, M.4
Rivera, A.A.5
Ulasov, I.V.6
-
111
-
-
0033841598
-
Inhibition of glioma cells in vitro and in vivo using a recombinant adenoviral vector containing an astrocyte-specific promoter
-
Vandier, D., Rixe, O., Besnard, F., Kim, M., Rikiyama, T., Goldsmith, M., et al. (2000). Inhibition of glioma cells in vitro and in vivo using a recombinant adenoviral vector containing an astrocyte-specific promoter. Cancer Gene Ther. 7, 1120-1126.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1120-1126
-
-
Vandier, D.1
Rixe, O.2
Besnard, F.3
Kim, M.4
Rikiyama, T.5
Goldsmith, M.6
-
112
-
-
0038467368
-
Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells
-
Wakimoto, H., Johnson, P. R., Knipe, D. M., and Chiocca, E. A. (2003). Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells. Gene Ther. 10, 983-990.
-
(2003)
Gene Ther.
, vol.10
, pp. 983-990
-
-
Wakimoto, H.1
Johnson, P.R.2
Knipe, D.M.3
Chiocca, E.A.4
-
113
-
-
63849225752
-
Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors
-
Wakimoto, H., Kesari, S., Farrell, C. J., Curry, W. T. Jr., Zaupa, C., Aghi, M., et al. (2009). Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res. 69, 3472-3481.
-
(2009)
Cancer Res.
, vol.69
, pp. 3472-3481
-
-
Wakimoto, H.1
Kesari, S.2
Farrell, C.J.3
Curry Jr., W.T.4
Zaupa, C.5
Aghi, M.6
-
114
-
-
32044446998
-
Retargeting of adenoviral vector using basic fibroblast growth factor ligand for malignant glioma gene therapy
-
Wang, W., Zhu, N. L., Chua, J., Swenson, S., Costa, F. K., Schmitmeier, S., et al. (2005). Retargeting of adenoviral vector using basic fibroblast growth factor ligand for malignant glioma gene therapy. J. Neurosurg. 103, 1058-1066.
-
(2005)
J. Neurosurg.
, vol.103
, pp. 1058-1066
-
-
Wang, W.1
Zhu, N.L.2
Chua, J.3
Swenson, S.4
Costa, F.K.5
Schmitmeier, S.6
-
115
-
-
48249125791
-
Malignant gliomas in adults
-
Wen, P. Y., and Kesari, S. (2008). Malignant gliomas in adults. N. Engl. J. Med. 359, 492-507.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
116
-
-
19944427873
-
Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates
-
Yang, W. Q., Lun, X., Palmer, C. A., Wilcox, M. E., Muzik, H., Shi, Z. Q., et al. (2004). Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates. Clin. Cancer Res. 10, 8561-8576.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 8561-8576
-
-
Yang, W.Q.1
Lun, X.2
Palmer, C.A.3
Wilcox, M.E.4
Muzik, H.5
Shi, Z.Q.6
-
117
-
-
0038069255
-
Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma
-
Yang, W. Q., Senger, D., Muzik, H., Shi, Z. Q., Johnson, D., Brasher, P. M., et al. (2003). Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma. Cancer Res. 63, 3162-3172.
-
(2003)
Cancer Res.
, vol.63
, pp. 3162-3172
-
-
Yang, W.Q.1
Senger, D.2
Muzik, H.3
Shi, Z.Q.4
Johnson, D.5
Brasher, P.M.6
-
118
-
-
71549150594
-
Human bone marrow-derived mesenchymal stem cells for intravascular delivery of oncolytic adenovirus Delta24-RGD to human gliomas
-
Yong, R. L., Shinojima, N., Fueyo, J., Gumin, J., Vecil, G. G., Marini, F. C., et al. (2009). Human bone marrow-derived mesenchymal stem cells for intravascular delivery of oncolytic adenovirus Delta24-RGD to human gliomas. Cancer Res. 69, 8932-8940.
-
(2009)
Cancer Res.
, vol.69
, pp. 8932-8940
-
-
Yong, R.L.1
Shinojima, N.2
Fueyo, J.3
Gumin, J.4
Vecil, G.G.5
Marini, F.C.6
-
119
-
-
52049099166
-
Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus
-
Zhang, X., Komaki, R., Wang, L., Fang, B., and Chang, J. Y. (2008). Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus. Clin. Cancer Res. 14, 2813-2823.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 2813-2823
-
-
Zhang, X.1
Komaki, R.2
Wang, L.3
Fang, B.4
Chang, J.Y.5
-
120
-
-
24644441665
-
Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo
-
Zhu, Z. B., Makhija, S. K., Lu, B., Wang, M., Rivera, A. A., Kim-Park, S., et al. (2005). Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo. Int. J. Oncol. 27, 237-246.
-
(2005)
Int. J. Oncol.
, vol.27
, pp. 237-246
-
-
Zhu, Z.B.1
Makhija, S.K.2
Lu, B.3
Wang, M.4
Rivera, A.A.5
Kim-Park, S.6
|